monocrotaline and Hypertrophy, Right Ventricular

monocrotaline has been researched along with Hypertrophy, Right Ventricular in 326 studies

Research

Studies (326)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	35 (10.74)	18.2507
2000's	101 (30.98)	29.6817
2010's	150 (46.01)	24.3611
2020's	40 (12.27)	2.80

Authors

Authors	Studies
Araujo, AS; Baldo, G; Belló-Klein, A; Campos-Carraro, C; Constantin, RL; Fernandes-Piedras, TRG; Schenkel, PC; Teixeira, RB; Türck, P; Visioli, F; Zimmer, A	1
Brodaczewska, K; Kieda, C; Mackiewicz, U; Mączewski, M; Oknińska, M; Paterek, A; Szczylik, C; Torbicki, A; Zajda, K; Zambrowska, Z	1
Crossman, DJ; Han, JC; Howe, K; Loiselle, DS; Ross, JM	1
Ding, D; He, Y; Jiang, H; Li, X; Liu, X; Xu, Y	1
Eklund, M; Khoruts, A; Moutsoglou, DM; Prins, KW; Prisco, AR; Prisco, SZ; Thenappan, T; Weir, EK	1
Agulham, AP; Bertoldi, AS; Gewehr, DM; Giovanini, AF; Kubrusly, FB; Kubrusly, LF; Mattar, BA; Nagashima, S	1
Goshima, Y; Goto, T; Hashimoto, T; Koga, M; Masukawa, D; Matsushita, N; Miyazaki, T; Mizuno, Y; Nakamura, F; Nakano, M; Niikura, R; Saito, M; Shimizu, T; Tamura, K; Uchimura, H; Zou, S	1
Jasińska-Stroschein, M	1
He, X; Hu, L; Li, L; Li, Q; Li, X; Shen, J; Tang, S; Tettey, AT; Wang, Y; Wang, Z; Wu, C; Yin, M; Zhao, C	1
Al-Qazazi, R; Archer, SL; Bentley, RET; Bonnet, S; Chen, KH; Dasgupta, A; Jones, O; Lima, PDA; Martin, AY; Maurice, DH; Mewburn, J; Potus, F; Prins, KW; Prisco, SZ; Provencher, S; Tian, L; Wu, D	1
Bai, X; Bi, YW; Bing, WD; Jiang, DT; Qu, QX; Song, GM; Sun, WY; Tuo, L; Zhao, X	1
Chen, S; Cui, H; Du, GQ; Li, Y; Shen, W; Sun, P; Wang, C; Xue, JY; Zhao, P	1
Cao, M; Li, S; Liu, H; Luan, J; Wang, J; Xue, Y; Zhai, C; Zhang, N; Zhang, Q; Zhu, Y	1
Balakin, AA; Gerzen, OP; Kuznetsov, DA; Lisin, RV; Mukhlynina, EA; Nikitina, LV; Protsenko, YL	1
Beserra, SS; de Lima Conceição, MR; Joviano-Santos, JV; Leal-Silva, P; Marques, LP; Roman-Campos, D; Souza, DS; Teixeira-Fonseca, JL	1
Araujo, ASDR; Belló-Klein, A; Campos-Carraro, C; de Lima-Seolin, BG; Teixeira, RB; Turck, P; Zimmer, A	1
Hanif, K; Jagavelu, K; Shafiq, M; Singh, N	1
Affatato, R; Cantoni, S; Ceriani, S; De Giorgio, D; De Logu, F; Facchinetti, F; Fumagalli, F; Latini, R; Letizia, T; Masson, S; Milioli, M; Nassini, R; Novelli, D; Olivari, D; Ristagno, G; Russo, I; Salio, M; Staszewsky, L; Trevisani, M	1
Cai, C; Lin, W; Wu, Y; Xiang, Y; Xu, J; Zeng, C; Zhao, H; Zhu, N	1
Cook, T; Daniell, H; Fisher, A; Gonnella, PA; Habibi, P; Kawut, SM; Lahm, T; Mangu, V; Park, J; Shi, Y; Yakubov, B; Zeng, L	1
An, N; Feng, W; Feng, Z; Guan, H; Hu, T; Hu, Y; Liu, J; Mao, Y; Mou, J; Zhang, D	1
Huang, J; Iacobas, DA; Iacobas, S; Mathew, R	1
Al-Omran, M; Bhatt, DL; Chowdhury, B; Connelly, KA; Hess, DA; Kabir, MG; Luu, AZ; Luu, VZ; Mazer, CD; Pan, Y; Quan, A; Sabongui, S; Teoh, H; Verma, S	1
Chen, H; Gao, X; He, K; Li, C; Li, H; Li, X; Liu, C; Wei, Q; Zhang, Z	1
Frede, W; Freichel, M; Gorenflo, M; Medert, R; Poth, T; Uhl, S; Vennekens, R	1
Chen, X; Dong, F; Guo, Z; Peng, Y; Zhang, J; Zhang, S; Zhu, L	1
Bialesova, L; Bouchard, A; Kinsella, BT; Mulvaney, EP; Reid, HM; Salvail, D	1
Dianat, M; Mard, SA; Radan, M; Saryazdi, SSN; Sohrabi, F	1
Jankowski, Z; Kocić, I; Sztormowska-Achranowicz, K	1
Beik, A; Iranpour, M; Jafarinejad Farsangi, S; Joukar, S; Kordestani, Z; Najafipour, H; Rajabi, S	1
Abe, K; Aoki, M; Aoki-Shoi, N; Bo, Z; Go, T; Hiraishi, K; Hirano, K; Inoue, R; Ishikawa, K; Kishi, H; Kobayashi, S; Koga, K; Kurahara, LH; Toru, S; Yahiro, E; Yamamura, A; Yokomise, H; Zhang, Y	1
Al-Qazazi, R; Archer, SL; Eklund, M; Hartweck, L; Hsu, S; Neuber-Hess, M; Potus, F; Prins, KW; Prisco, SZ; Rose, L; Thenappan, T; Tian, L; Wu, D	1
Bertoldi, AS; Coltro, GA; Gewehr, DM; Kubrusly, FB; Kubrusly, LF; Noronha, L; Preto, PC; Salgueiro, GR; Vieira, HI	1
Aparicio Cordero, EA; Araujo, AS; Bahr, AC; Baldo, G; Belló-Klein, A; Campos-Carraro, C; Constantin, RL; Donatti, L; Gonzalez, E; Luz de Castro, A; Ortiz, VD; Teixeira, RB; Visioli, F; Zimmer, A	1
Abdul-Salam, VB; Alvarez-Laviada, A; Dries, E; Faggian, G; Gorelik, J; Medvedev, R; Miragoli, M; Rossi, S; Sanchez-Alonso, JL; Schorn, T; Trayanova, N; Wojciak-Stothard, B	1
Huang, B; Li, L; Li, S; Luo, Y; Tang, C; Xu, S	1
Higuchi, T; Inagaki, T; Masaki, T; Nakaoka, Y; Pearson, JT; Saito, S; Schwenke, DO; Shirai, M; Tsuchimochi, H; Umetani, K	1
Guo, J; Huo, S; Li, S; Lin, L; Luo, P; Lv, J; Peng, L; Shi, W; Wang, M; Yan, D; Zhang, C	1
Borges, RS; Duarte, GP; Gonzaga-Costa, K; Lahlou, S; Magalhães, PJC; Rebouça, CDSM; Rodrigues-Silva, MJ; Vasconcelos-Silva, AA	1
Cao, Y; Chen, F; Chu, C; Ding, J; Fulton, D; Hu, L; Huang, H; Li, K; Li, Y; Xu, P; Yu, Y	1
Askaripour, M; Beik, A; Jafari, E; Jafarinejad-Farsangi, S; Joukar, S; Najafipour, H; Rajabi, S; Safi, Z	1
Blackhurst, D; Cour, M; Diaba-Nuhoho, P; Hadebe, N; Lecour, S; Marais, D	1
Choi, SJ; Hong, YM; Kim, KC; Lee, H	1
Imoto, K; Okada, M; Yamawaki, H	1
Chen, W; Dong, J; Gao, D; Guo, H; Lu, Y; Pan, X; Sun, Y; Xu, D; Xu, Y	1
Cai, X; Huang, X; Jiang, Z; Lin, Z; Wang, H; Xie, L	1
Bergmeister, H; Bonderman, D; Eilenberg, M; Kiss, A; Mascherbauer, J; Podesser, B; Schreiber, C	1
Ji, W; Lin, C; Mi, L; Yu, W	1
Ciambarella, BT; Fragoso, IT; Gomes, FODS; Oliveira, AC; Peixoto, CA; Ramos, IPR; Ribeiro, EL; Silva, AKSE; Silva, PME	1
Li, Q; Wang, J; Wu, X; Xie, J; Xu, Y; Yu, J; Zeng, Z; Zhu, X	1
Higuchi, M; Hikasa, Y; Leong, ZP; Okida, A; Yamano, Y	1
Fu, N; Liang, Y; Shi, R; Wang, C; Wang, X; Wang, Y; Wei, Z; Xing, J; Yin, S; Zhu, D	1
Crossman, DJ; Hickey, AJ; Loiselle, DS; Power, AS; Ward, ML	1
Abdelmonsif, DA; ElAchy, SN; Hassaan, PS; Nassar, SZ	1
Tan, HR; Yang, JM; Yu, JQ; Zhang, M; Zhou, R	1
Bueno-Beti, C; Hadri, L; Hajjar, RJ; Sassi, Y	1
Chai, L; Feng, W; Li, C; Li, M; Li, S; Liu, P; Shi, W; Wang, J; Wang, Q; Yan, X; Zhai, C; Zhang, Q; Zhu, Y	1
Hikasa, Y; Leong, ZP	1
Cheng, Y; He, M; Kong, H; Wang, H; Xie, W; Xu, J; Yu, M	1
Du, A; Gong, J; Huang, B; Lian, G; Wang, H; Xiao, G; Xie, L; Xu, C; Zhuang, W	1
Belló-Klein, A; Campos-Carraro, C; Corssac, GB; da Rosa Araujo, AS; de Lima-Seolin, BG; Dos Santos Lacerda, D; Hickmann, A; Llesuy, S; Tavares, AMV; Teixeira, RB; Turck, P	1
Iesaki, K; Matsumura, Y; Murata, Y; Nakagawa, K; Ohkita, M; Sawano, T; Tanaka, R; Tawa, M; Yamanaka, M; Yano, Y	1
Ding, XY; Guo, DC; Li, C; Li, YD; Lu, XZ; Shi, YP; Wang, YD; Wu, XP	1
Abe, K; Hirano, K; Hirano, M; Hirooka, Y; Kuwabara, Y; Sunagawa, K; Tanaka-Ishikawa, M; Tsutsui, H	1
Adthapanyawanich, K; Chootip, K; Demougeot, C; Ingkaninan, K; Temkitthawon, P; Totoson, P; Wisutthathum, S	1
Chen, X; Hu, Q; Huang, L; Zhou, W	1
Gao, P; Li, Y; Si, J; Yang, B; Yu, J	1
Huang, CH; Huang, H; Li, YY; Liu, JC; Liu, ZB; Wu, QC; Xu, H; Xu, QR; Zeng, L; Zhou, XL; Zhu, RR	1
Cai, KF; Chen, HQ	1
Adams, V; Boekschoten, MV; Bowen, TS; van Norren, K; Vinke, P; Witkamp, RF	1
Akers, S; Ambrosini, R; Champion, HC; Glickman, S; Haight, D; Lachant, DJ; Meoli, DF; Staicu, S; White, RJ	1
Bendjelloul, F; Courtman, DW; Deng, Y; Ormiston, ML; Parker, TG; Rundle, N; Stewart, DJ; Tsoporis, JN	1
Barrier, M; Biardel, S; Bisserier, M; Bonnet, P; Bonnet, S; Breuils-Bonnet, S; Carter, S; Courchesne, A; Courture, C; Deshaies, Y; Lauzon-Joset, JF; Majka, SM; Meloche, J; Paulin, R; Picard, F; Provencher, S; Racine, C; Tremblay, É	1
Alencar, AK; Barreiro, EJ; Caruso-Neves, C; de Sant'Anna, CM; Ferraz, EB; Fraga, CA; Kümmerle, AE; Landgraf, SS; Maia, RC; Montagnoli, TL; Nascimento, JH; Pereira, SL; Sudo, RT; Tesch, R; Zapata-Sudo, G	1
Comunoglu, C; Macit, A; Silan, C; Uzun, O; Yavuz, O; Yavuz, T; Yildirim, HA; Yuksel, H	1
Li, G; Li, X; Li, Z; Liu, A; Liu, Y; Su, J; Sun, L; Xu, Y; Zhu, Y	1
Eguchi, A; Hao, H; Hirota, S; Hirotani, S; Hosokawa, M; Iwasaku, T; Masuyama, T; Naito, Y; Ohyanagi, M; Okuhara, Y; Sawada, H; Tsujino, T	1
Bartelds, B; Berger, RM; Borgdorff, MA; de Vroomen, M; Dickinson, MG; Steendijk, P	1
Chen, GY; Hu, Y; Lin, MJ; Liu, Q; Liu, XR; Sham, JS	1
Hayashi, T; Maruyama, J; Maruyama, K; Mitani, Y; Okada, A; Sawada, H; Suzuki, K; Yamada, Y; Yokochi, A; Zhang, E	1
Atli, O; Bal, E; Ergun, B; Ilgin, S; Sirmagul, B	1
Chen, Z; Dixon, RA; Ruan, KH; So, SP; Vanderslice, P; Willerson, JT; Zhou, L	1
Aliotta, JM; Amaral, A; El-Bizri, R; Hasslinger, A; Igbinoba, Z; Klinger, JR; Pereira, M; Quesenberry, PJ; Rounds, SI; Sorokina, A	1
He, B; Kang, B; Wang, Z; Xiao, J; Xie, B; Zhang, Y	1
Baber, S; Kadowitz, PJ; Lasker, GF; Lasky, JA; Pankey, EA; Thammasiboon, S	1
Fernandez, R; Guo, Q; Huang, JA; Yamamura, A; Yamamura, H; Yuan, JX; Zimnicka, AM	1
Gu, WW; Li, HT; Liao, HX; Liu, BH; Liu, R; Qian, YX; Wu, QH; Zeng, GQ; Zhang, XF; Zhao, J	1
Du, TX; Qin, N; Wei, LW	1
Gupta, S; Janssen-Heininger, Y; Kim, IK; Li, L; Wei, C	1
Alencar, AK; Barreiro, EJ; Caruso-Neves, C; Cunha, Vdo M; da Silva, FE; Ferraz, EB; Fraga, CA; Lima, LM; Mendes, LV; Montagnoli, TL; Nascimento, JH; Pereira, SL; Sant'anna, CM; Sudo, RT; Tesch, R; Zapata-Sudo, G	1
Jasińska-Stroschein, M; Orszulak-Michalak, D; Owczarek, J; Plichta, P	1
Chen, YF; Creighton, JR; Fu, J; Guo, Y; Hage, FG; Oparil, S; Xing, DD; Zhao, X	1
Brinckmann, J; Herold, S; Mayer, K; Mižíková, I; Morty, RE; Nave, AH; Niess, G; Reichenberger, F; Seeger, W; Steenbock, H; Talavera, ML; Vadász, I; Veit, F; Weissmann, N	1
Chen, IJ; Dai, ZK; Huang, CH; Liu, CP; Wu, BN; Wu, JR; Yeh, JL	1
Goto, T; Kawakami, H; Koga, M; Mizuno, Y; Watanabe, I	1
Asmis, R; Barabutis, N; Barman, SA; Black, SM; Catravas, JD; Chen, F; Dimitropoulou, C; Fulton, DJ; Giannis, A; Han, W; Jonigk, D; Keri, G; Orfi, L; Rafikov, R; Rafikova, O; Ramesh, G; Stepp, DW; Su, Y; Szabadkai, I; Szantai-Kis, C; Wang, Y	1
Inoue, H; Ito, T; Kawahara, K; Maruyama, I; Noma, S; Oyama, Y; Sadamura-Takenaka, Y; Yamada, S	1
Alemanni, M; Altomare, C; Barile, L; Cornaghi, L; Gobbi, M; Latini, R; Lucchetti, J; Mostacciuolo, G; Rizzetto, R; Rocchetti, M; Ronchi, C; Russo, I; Sala, L; Staszewsky, LI; Zambelli, V; Zaza, A	1
Arvapalli, R; Blough, ER; Dornon, L; Hamlekhan, A; He, K; Kolli, MB; Ma, JY; Manne, NDPK; Nalabotu, SK; Nandyala, G; Para, R; Rice, KM; Shokuhfar, T; Wehner, PS	1
Haga, S; Hamano, T; Hirai, T; Ishizaka, Y; Mimori, A; Tsuchiya, H	1
Jasińska-Stroschein, M; Orszulak-Michalak, D; Owczarek, J; Wesołowska, A	1
Chun, HJ; Comhair, SA; Erzurum, SC; Hu, X; Hwangbo, C; Ju, H; Kang, Y; Kim, J; McLean, DL; Mehrotra, D; Papangeli, I; Park, H	1
Kuznetsov, D; Lookin, O; Protsenko, Y	1
Gupta, S; Kim, IK; Li, L; Wei, C; Wu, L	1
Chang, HJ; Kang, WJ; Kim, DH; Lee, SE; Lee, YJ; Shin, JS; Yang, PS	1
Hanif, K; Kaur, G; Lingeshwar, P; Siddiqui, HH; Singh, N	1
Bruce, E; Espejo, A; Francis, J; Horowitz, A; Katovich, MJ; Nair, A; Oswalt, A; Raizada, MK; Rathinasabapathy, A; Shenoy, V; Steckelings, UM; Sumners, C; Unger, T	1
Jasińska-Stroschein, M; Kącikowska, J; Orszulak-Michalak, D; Owczarek, J; Surowiecka, A	1
Dias-Neto, M; Eloy, C; Ferreira-Pinto, M; Gonçalves, D; Gonçalves, N; Henriques-Coelho, T; Leite-Moreira, AF; Lopes, JM; Luísa-Neves, A; Mendes, M; Pinho, S	1
Qiu, M; Zhang, R; Zhang, W; Zheng, Y	1
Furutani, Y; Hayama, E; Kawaguchi, N; Lan, B; Nakanishi, T	1
Ding, M; Fu, E; Jin, F; Lei, J; Li, Z; Liu, S; Ma, F; Qu, Y; Xin, W; Zhang, H	1
Balestra, GM; Eerbeek, O; Mik, EG; Specht, PA; van der Laarse, WJ; Zuurbier, CJ	1
Huang, XN; Qin, N; Wei, LW	1
Fukayama, T; Fukushima, R; Goya, S; Nakata, TM; Tanaka, R; Yoshiyuki, R	1
Brown, MB; Chingombe, TJ; Cooney, SA; Fisher, AJ; Lahm, T; Novack, RA; Petrache, I; Presson, RG; Reddy, JG; Zinn, AB	1
Araújo, AS; Belló-Klein, A; Colombo, R; Conzatti, A; Fernandes, TR; Siqueira, R; Tavares, AM	1
Cho, MS; Choi, SJ; Hong, YM; Kim, KC; Kwon, JH; Lee, H; Lee, JC; Lee, SJ; Oh, W; Seo, ES; Wang, TJ; Yang, YS	1
Antigny, F; Bonnet, S; Breuils-Bonnet, S; Johnson, I; Le Guen, M; Meloche, J; Perros, F; Potus, F; Provencher, S; Ranchoux, B; Tremblay, E; Vinck, J	1
Eddahibi, S; Fadel, E; Humbert, M; Jacquin, S; Londoño-Vallejo, A; Mercier, O; Mignotte, B; Richard, S; Rincheval, V	1
Blackhurst, D; Blauwet, L; Butrous, G; Davies, N; Lecour, S; Maarman, G; Sliwa, K; Thienemann, F	1
Fan, F; Fan, Y; Feng, W; Ke, R; Li, F; Li, M; Li, S; Liu, L; Pan, Y; Song, Y; Wang, X; Xie, X; Zhai, C; Zhang, Y; Zhu, Y	1
Cicha, K; Jasińska-Stroschein, M; Orszulak-Michalak, D; Owczarek, J	1
Jiang, Y; Ye, L; Zuo, X	1
Centala, A; Eghbali, M; Sharma, S; Umar, S	1
Chen, C; Dong, W; Lin, X; Lv, S; Tong, G; Wang, X; Yang, D; Yang, Y	1
Bhatta, RS; Hanif, K; Kaur, G; Laxman, TS; Lingeshwar, P; Mishra, A; Ramakrishna, R; Shukla, S; Siddiqui, HH; Singh, N; Singh, S	1
Hara, Y; Hashizume, K; Ishiguro-Oonuma, T; Kizaki, K; Okada, M; Suemoto, M; Yoshioka, K	1
Higano, S; Ishiyama, A; Kajimura, I; Minamisawa, S; Ono, Y; Yasuda, S	1
Baldus, S; Behringer, A; Berghausen, EM; Blaschke, F; Caglayan, E; Er, F; Gassanov, N; Kappert, K; Odenthal, M; Rosenkranz, S; Ten Freyhaus, H; Trappiel, M; Wellnhofer, E	1
Akagi, S; Egashira, K; Ito, H; Kondo, M; Matoba, T; Matsubara, H; Miura, D; Nakamura, K	1
Ahmed, A; Gu, J; Gu, Y; Guo, D; Jiang, H; Zhang, Z	1
Cheng, CC; Chiou, KR; Chiou, SH; Huang, WC; Ke, MW; Liu, CP; Mar, GY; Pan, HW; Shu, CW; Tseng, CJ; Wann, SR	1
Gong, K; Hu, F; Mu, X; Sun, X; Wang, Y; Wu, F; Yang, D; Zhang, Z; Zheng, G	1
Antigny, F; Belacel-Ouari, M; Bonnet, S; Bourgeois, A; Breuils-Bonnet, S; Dorfmüller, P; Fadel, E; Girerd, B; Hautefort, A; Humbert, M; Jourdon, P; Manoury, B; Meloche, J; Montani, D; Nadeau, V; Péchoux, C; Perros, F; Potus, F; Provencher, S; Ranchoux, B; Rucker-Martin, C; Ruffenach, G; Simonneau, G; Tremblay, E	1
Black, SM; Desai, AA; Fineman, JR; Garcia, JG; Kinchen, JM; Maltepe, E; Meadows, ML; Mohney, RP; Rafikov, R; Rafikova, O; Yuan, JX	1
Aliotta, JM; Baird, GL; Del Tatto, M; Dooner, MS; Goldberg, LR; Klinger, JR; Papa, E; Pereira, M; Quesenberry, PJ; Ventetuolo, CE; Wen, S	1
Heo, J; Kim, IG; Kim, K; Kim, KH; Kim, Y; Lee, S; Lee, SW; Lim, J; Shin, DM	1
Imoto, K; Kumatani, S; Okada, M; Yamawaki, H	1
Han, X; Long, Y; Zhang, X; Zhang, Y; Zhou, Z	1
Campos, DH; Carvalho, RF; Cicogna, AC; de Almeida Sabela, AK; Mariano, TB; Okoshi, K; Pacagnelli, FL; Vanderlei, LC	1
Chen, Y; Duan, X; Jiang, Q; Li, M; Lu, W; Sun, D; Tang, H; Wang, J; Wang, Z; Xu, L; Yang, K; Zhang, J	1
Hu, W; Huang, J; Lv, L; Xiang, Y; Ye, S; Zeng, C; Zhao, X; Zhu, N	1
Adorini, L; Cellai, I; Comeglio, P; Filippi, S; Maggi, M; Maneschi, E; Morelli, A; Sarchielli, E; Vannelli, GB; Vignozzi, L	1
Chlopicki, S; Fedorowicz, A; Jakubowski, A; Kopec, G; Kutryb-Zając, B; Mateuszuk, Ł; Skórka, T; Słomińska, E; Walczak, M; Zakrzewska, A; Łomnicka, M	1
Lee, BH; Lee, JH; Lim, CJ; Oh, KS; Park, BK; Seo, HW; Yi, KY	1
Ali, Q; Sun, Z; Varshney, R; Wu, C	1
Roshchevskaya, IM; Smirnova, SL; Suslonova, OV	1
Cheng, Y; Gao, H; Gong, B; Hu, J; Huang, L; Li, W; Liu, H; Qiao, C; Wang, X; Zhao, C; Zong, L	1
Ahsan, F; Gupta, N; McMurtry, IF; Nozik-Grayck, E; Rashid, J; Stenmark, KR	1
Cheng, G; He, L; Li, Y; Wang, X	1
Cai, ZY; He, B; Li, J; Pu, J; Shen, JY; Sun, LY; Yang, CD	1
Hao, Y; Niu, Y; Sun, T; Wu, F; Xu, Y; Yan, L; Yang, J; Yao, W; Yu, J; Zhou, R	1
Cao, Y; Luo, H; Qin, G; Wang, E; Wang, L; Ye, Z; Yin, X; Zhang, J; Zhang, Z	1
Bardou, M; Dumas, M; Goirand, F; Guerard, P; Lirussi, F; Rakotoniaina, Z; Rochette, L	2
Brandão-Nogueira, A; Correia-Pinto, J; Henriques-Coelho, T; Leite-Moreira, AF; Moreira-Gonçalves, D	1
Gong, QH; Huang, XN; Qin, N; Wei, LW; Wu, Q	1
Amano, S; Arai, Y; Chandra, BI; Hirose, K; Ikeda, T; Kimura, Y; Komeda, M; Kushibiki, T; Marui, A; Sakaguchi, H; Tabata, Y; Yuang, H	1
Hara, Y; Harada, T; Hori, Y; Kikuzuki, R; Okada, M; Yamawaki, H	1
Iino, K; Ito, H; Koyama, T; Murakami, M; Ohba, T; Ono, K; Watanabe, H	1
Beach, S; Budd, DC; Crosby, A; Davies, RJ; Docx, C; Duggan, N; England, K; Holmes, AM; Leblanc, C; Lebret, C; Morrell, NW; Raza, F; Schindler, F; Thomas, M; Walker, C	1
Ellinghaus, P; Janssen, W; Kast, R; Klein, M; Kramer, F; Lustig, K; Milting, H; Schäfer, S	1
He, JG; Tan, XY	1
Gao, YH; Hao, XQ; Li, XH; Su, M; Wang, XQ; Xu, YL; Yang, DL; Yang, XJ; Zhang, HG	1
Falcão-Pires, I; Gonçalves, N; Henriques-Coelho, T; Leite-Moreira, AF; Moreira-Gonçalves, D; Roncon-Albuquerque, R	1
Hasegawa, Y; Inaji, H; Matsumura, Y; Nakagawa, E; Nishida, M; Ohkita, M; Tanida, I	1
Gao, YH; Hao, XQ; Li, XH; Xu, YL; Yang, DL; Yang, XJ; Zhang, HG	1
Chang, LT; Chua, S; Kao, YH; Ko, SF; Sheu, JJ; Sun, CK; Yen, CH; Yip, HK; Yuen, CM	1
Abe, Y; Daicho, T; Marunouchi, T; Ohara, M; Takano, S; Takeo, S; Tanonaka, K; Yagi, T	1
den Adel, B; Hessel, M; Schutte, C; Steendijk, P; van der Laarse, A	1
Atsma, DE; Bax, WH; de Visser, YP; Laghmani, el H; Mantikou, E; Pijnappels, DA; Schalij, MJ; Schutte, CI; Steendijk, P; Umar, S; van der Laarse, A; van der Wall, EE; Wagenaar, GT	1
Hara, Y; Harada, T; Kikuzuki, R; Okada, M; Yamawaki, H	1
Asai, K; Ishikawa, M; Mizuno, K; Sato, N; Takano, T	1
Liu, B; Liu, HM; Wang, XM; Wang, XQ; Yu, L; Zhou, TF	1
Daicho, T; Daisho, Y; Kojima, S; Marunouchi, T; Takagi, N; Takano, S; Takeo, S; Tanonaka, K; Tejima, Y	1
Musters, RJ; Paulus, WJ; Redout, EM; Simonides, WS; van de Kolk, CW; van der Toorn, A; van Echteld, CJ; van Hardeveld, C; Zuidwijk, MJ	1
Jiang, W; Jiang, Z; Li, B; Li, Y; Wang, C; Zeng, Z	1
Aoki, S; Boveda-Ruiz, D; D'Alessandro-Gabazza, CN; Gabazza, EC; Gil-Bernabe, P; Miyake, Y; Morser, J; Qin, L; Ramirez Marmol, AY; San Martin Montenegro, VT; Taguchi, O; Takagi, T; Takei, Y; Toda, M; Yano, Y	1
Dackor, RT; Li, R; Ma, B; Tu, L; Wang, DW; Wang, L; Xu, X; Zeldin, DC; Zheng, C	1
Cho, YK; Choi, WY; Eom, GH; Kee, HJ; Kim, HS; Kook, H; Ma, JS; Nam, KI	1
de Boer, MA; Mouchaers, KT; Postmus, PE; Schalij, I; van der Laarse, WJ; van Hinsbergh, VW; van Nieuw Amerongen, GP; Vonk Noordegraaf, A	1
Al-Mousily, F; Byrne, BJ; Embury, J; Gannon, KS; Germain, S; Jacques, V; Murray, J; Porvasnik, SL; Shacham, S	1
Campian, ME; de Bakker, JM; de Bruin, K; Hardziyenka, M; Tan, HL; van Eck-Smit, BL; Verberne, HJ	1
Archer, SL; Fang, YH; Haber, I; Thenappan, T; Urboniene, D	1
Chung, MJ; Gao, S; Kim, SH; Lee, YH; Oh, YB; Park, WH; Shah, A	1
Chen, JZ; Du, CQ; Hu, H; Hu, XS; Li, N; Wang, K; Yao, L; Zeng, CL; Zhang, FR	1
Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Wu, YP; Xia, ZL; Zhao, XM	1
Angeli, FS; Bernstein, HS; Boyle, AJ; De Marco, T; Jahn, S; Koskenvuo, JW; Mirsky, R; Ritner, C; Sievers, RE; Yeghiazarians, Y; Yim, SM	1
Benoist, D; Bernus, O; Drinkhill, M; Stones, R; White, E	1
Endoh, H; Fukuda, K; Hirose, M; Miura, M; Nakano, M; Shimokawa, H; Shindoh, C; Shirato, K; Sugai, Y; Wakayama, Y	1
Cornitescu, T; Dahal, BK; Ghofrani, HA; Grimminger, F; Hoffmann, J; Kaulen, C; Kosanovic, D; Kuebler, WM; Reiss, I; Savai, R; Schermuly, RT; Seeger, W; Weissmann, N	1
Wang, HL; Wang, Y; Zhang, XH	1
Delbeck, M; Ellinghaus, P; Kast, R; Laux, V; Nickel, KF; Perzborn, E; Schäfer, S; Schermuly, RT; Strassburger, J; von Degenfeld, G	1
Brandes, RP; Cornitescu, T; Dahal, BK; Davie, N; Ghofrani, HA; Grimminger, F; Janssen, W; Kojonazarov, B; Kosanovic, D; Luitel, H; Schermuly, RT; Seeger, W; Sydykov, A; Weissmann, N	1
Bache, RJ; Chen, Y; Fassett, J; Geurts, AM; Guo, H; Hu, D; Hu, X; Lu, Z; Ostertag, E; Somani, A; Tang, Q; Weir, EK; Xu, D; Xu, X; Xu, Y	1
Eghbali, M; Li, J; Maltese, F; Nadadur, RD; Partownavid, P; Umar, S; van der Laarse, A	1
Liu, CP; Lu, WX; Yu, BX; Zhang, WH; Zhang, YJ	1
Anderson, ME; Chen, B; Grumbach, IM; Guo, A; Li, Y; Sanders, P; Song, LS; Wang, LC; Weiss, RM; Xie, YP; Zimmerman, K	1
Baker, KM; Gupta, S; Jones, WK; Kim, IK; Kumar, R; Kumar, S; Seqqat, R; Thomas, CM; Wei, C	1
Lu, Y; Luan, Y; Wang, YB; Wei, DE; Zhang, ZH	1
Clozel, M; Hess, P; Rey, M	1
Campen, MJ; Channell, MM; Lucas, SN; Naik, JS; Paffett, ML	1
Badejo, AM; Casey, DB; Kadowitz, PJ; Lasker, GF; Murthy, SN; Nossaman, BD; Pankey, EA; Riehl, RA	1
Berghausen, EM; Brandes, RP; Butrous, E; Butrous, G; Dabral, S; Dahal, BK; Ghofrani, HA; Grimminger, F; Pullamsetti, SS; Rosenkranz, S; Savai, R; Schermuly, RT; Seeger, W; Tretyn, A; Weissmann, N	1
Guan, RJ; Li, JJ; Li, XL	1
Dong, H; Fernandez, RA; Guo, Q; Makino, A; Pohl, NM; Smith, KA; Yamamura, A; Yamamura, H; Yuan, JX; Zeifman, A; Zimnicka, AM	1
Blaudszun, G; Morel, DR	1
Cui, W; Li, J; Long, C; Wang, H	1
Ji, YQ; Liu, CP; Lu, WX; Zeng, Q; Zhang, WH; Zhang, YJ	1
Ayon, RJ; Davis, AJ; Duan, DD; Forrest, AS; Freitas, N; Greenwood, IA; Huebner, ML; Joyce, J; Joyce, TC; Leblanc, N; Singer, CA; Valencik, ML; Wiwchar, M; Ye, L	1
Ceribasi, AO; Demir, T; Kaplan, DS; Kisacik, B; Onat, AM; Orkmez, M; Pehlivan, Y; Sayarlioglu, M; Taysi, S; Turkbeyler, IH; Tutar, E	1
Adamy, C; Chassagne, C; Eddahibi, S; Oliviero, P; Rappaport, L; Samuel, JL; Teiger, E	1
Brindley, DN; DeAlmeida, J; Mitani, Y; Mutlu, A; Rabinovitch, M; Russell, JC	1
Egashira, K; Ikeda, Y; Kataoka, C; Kitamoto, S; Nishida, K; Sueishi, K; Takeshita, A; Yamaoka, T; Yonemitsu, Y	1
Berry, GJ; Faul, JL; Kao, PN; Nishimura, T; Pearl, RG; Qiu, D; Vaszar, LT	1
Beilfuss, A; Brandt, K; Brodde, OE; Heinroth-Hoffmann, I; Leineweber, K; Pönicke, K; Wludyka, B	1
Bernocchi, P; Boraso, A; Cargnoni, A; Ceconi, C; Dalla Libera, L; Ferrari, R; Parrinello, G; Vescovo, G	1
Chen, MJ; Lai, YL	1
Berry, GJ; Faul, JL; Kao, PN; Nishimura, T; Pearl, RG	1
Cernacek, P; Dupuis, J; Jasmin, JF	1
Brodde, OE; Hartmann, O; Hasenfuss, G; Kögler, H; Leineweber, K; Nguyen van, P; Schott, P	1
Heslinga, JW; Sipkema, P; Versluis, JP; Westerhof, N	1
Ahn, BH; Cho, HG; Lee, HA; Lee, WJ; Lee, YM; Park, HK; Yang, EK	1
Hashimoto, K; Iwase, M; Kanazawa, H; Kato, Y; Kawata, N; Koike, Y; Nishimura, M; Nishizawa, T; Noda, A; Takagi, K; Yokoi, T; Yokota, M; Yoshimori, Y	1
Bongrani, S; Cargnioni, A; Ferrari, R; Gitti, GL; Pasini, E; Pastore, F; Razzetti, R	1
Abe, K; Hattori, T; Kaibuchi, K; Matsumoto, Y; Morikawa, K; Nakashima, Y; Oi, K; Shimokawa, H; Sueishi, K; Takeshit, A; Uwatoku, T	1
Brunner, F; Stessel, H	1
Austin, DJ; Elefteriades, JA; Goldstein, L; Keane, J; Kopf, GS; Lovoulos, C; Rocco, E; Singh, S; Tang, P; Tittle, S	1
Cui, B; Dai, DZ; Zhang, TT	1
Ermert, L; Ghofrani, HA; Grimminger, F; Kreisselmeier, KP; Pullamsetti, S; Samidurai, A; Schermuly, RT; Schudt, C; Seeger, W; Weissmann, N	1
Eshiro, K; Matsumura, Y; Nishida, M; Okada, Y; Takaoka, M	1
Baptista, MJ; Brandão-Nogueira, A; Correia-Pinto, J; Fortunato, JM; Henriques-Coelho, T; Leite-Moreira, AF; Lourenço, AP; Oliveira, SM; Roncon-Albuquerque, R; Teles, A	1
Gewitz, M; Huang, J; Mathew, R; Patel, K; Sehgal, PB; Shah, M	1
Bonnet, S; Dyck, JR; Haromy, A; Hashimoto, K; McMurtry, MS; Michelakis, ED; Wu, X	1
Bonartsev, AP; Medvedeva, NA; Postnikov, AB; Slavutskaia, Av	1
Fukushima, N; Matsuda, H; Nakamura, T; Ono, M; Sawa, Y; Suhara, H; Tanabe, T; Yokoyama, C	1
Chong, AJ; Hampton, CR; Lu, J; Onoda, K; Pohlman, TH; Shimamoto, A; Shimpo, H; Spring, DJ; Takao, M; Verrier, ED; Yada, I; Yada, M	1
Imaizumi, T; Kai, H; Matsui, H; Mori, T; Niiyama, H; Numaguchi, Y; Okumura, K; Sugi, Y; Tahara, N; Takayama, N; Yasukawa, H	1
Brodde, OE; Dihazi, H; Hasenfuss, G; Kögler, H; Leineweber, K; Neddermeier, D; Regitz-Zagrosek, V; Schmidt, B; Schott, P; Singer, SS	1
Colvin, K; Gebb, S; Imamura, M; Ivy, DD; Jones, PL; Lee, DS; McMurtry, IF; Oka, M	1
Jackson, EK; Mady, HH; Melhem, MF; Salah, EM; Tofovic, SP	1
Ku, DD; Sun, X	3
Dai, ZK; Huang, XN; Jiang, QS; Shi, JS; Wu, Q; Yang, GZ; Zhou, QX	2
Castro-Chaves, P; Henriques-Coelho, T; Leite-Moreira, AF; Rocha-Sousa, A; Soares, JB	1
Fukuchi, Y; Homma, N; Morio, Y; Muramatsu, M; Sato, K; Suzuki, T; Takahashi, H; Yamamoto, A	1
Bongalon, S; Dai, YP; Mutafova-Yambolieva, VN; Parks, SD; Tian, H; Yamboliev, IA	1
Jin, D; Katayama, H; Kishi, K; Miyazaki, M; Muramatsu, M; Takai, S; Tamai, H	1
Hadama, T; Hashimoto, Y; Inagaki, S; Kaku, T; Kimura, K; Li, Y; Miyamoto, S; Ono, K; Takebayashi, S	1
den Adel, B; Hessel, MH; Schutte, CI; Steendijk, P; van der Laarse, A	1
Dacic, S; Jackson, EK; Petrusevska, G; Tofovic, SP; Zhang, X	1
Dupuis, J; Jasmin, JF; Lisanti, MP; Mercier, I; Tanowitz, HB	1
Lamberts, RR; Stienen, GJ; Vaessen, RJ; Westerhof, N	1
Hongo, M; Hoshikawa, Y; Ikeda, U; Ise, H; Ito, T; Izawa, A; Kobayashi, E; Miyashita, H; Morimoto, H; Shimada, K; Suzuki, C; Takahashi, M	1
Baber, SR; Bunnell, BA; Deng, W; Hyman, AL; Kadowitz, PJ; Master, RG; Murthy, SN; Taylor, BK	1
Endo, K; Hirota, M; Inai, Y; Iwasaki, T; Kajiya, F; Kajiya, M; Kiyooka, T; Mohri, S; Morimoto, T; Naruse, K; Ogasawara, Y; Ohe, T; Shimizu, J; Yada, T	1
Azuma, H; Doi, S; Mizutani, S; Sasaki, A	1
Fukuchi, Y; Homma, N; Morio, Y; Muramatsu, M; Nagaoka, T; Sato, K; Takahashi, H; Yamamoto, A	1
Fukuda, K; Ieda, M; Kanazawa, H; Kimura, K; Kurosawa, H; Mochizuki, H; Ninomiya, S; Ogawa, S; Tsunoda, M; Yagi, T; Yamazaki, K; Yoshimi, K	1
Draisma, HH; Henkens, IR; Maan, AC; Mouchaers, KT; Schalij, I; Schalij, MJ; Swenne, CA; van der Laarse, WJ; van der Wall, EE; Vliegen, HW; Vonk-Noordegraaf, A	1
Blaxall, BC; Cool, CD; Galaria, II; Hall, CM; Harvey, JL; Kallop, DY; Meoli, DF; Miller, CM; Pierce, RA; Swarthout, RF; Taubman, MB; White, RJ	1
Caldenhoven, E; Lamberts, RR; Lansink, M; St Cyr, JA; Stienen, GJ; Vaessen, RJ; Witte, G	1
Ikeda, U; Ito, T; Kume, A; Mimuro, J; Miyashita, H; Mizukami, H; Okada, T; Ozawa, K; Sakata, Y; Shimada, K; Takahashi, M; Uchibori, R; Urabe, M	1
Guan, Q; Liu, H; Liu, ZY	1
Fukumoto, Y; Shimokawa, H; Tawara, S	1
Atsma, D; Bax, W; Hessel, M; Schalij, M; Schutte, C; Steendijk, P; Umar, S; van der Laarse, A; van der Wall, E	1
Liu, B; Liu, T; Wang, XM; Wei, L; Zhao, L; Zhou, TF	1
Dony, E; Dumitrascu, R; Flockerzi, D; Ghofrani, HA; Grimminger, F; Lai, YJ; Pullamsetti, SS; Savai, R; Schermuly, RT; Schudt, C; Seeger, W; Weissmann, N	1
Ikeda, M; Ito, K; Ito, KM; Kato, T; Nasu, T; Sonoda, H	1
Edwards, JG; Frishman, WH; Gewitz, MH; Huang, J; Kaminski, PM; Mathew, R; Wolin, MS; Yeh, A	1
Auzani, JA; Belló-Klein, A; Khaper, N; Picoral, M; Silva, LF; Souza-Rabbo, MP	1
Enomoto, K; Hashimoto, M; Honda, M; Kuramochi, T; Morioka, S; Tanaka, K	1
Onodera, S; Tobise, K; Yoshie, H	1
Agnoletti, G; Albertini, A; Comini, L; Ferrari, R; Gaia, G; Mantero, G; Panzali, A; Pasini, E	1
Arend, WP; Bridges, J; Tuder, RM; Voelkel, NF	1
Enomoto, K; Hashimoto, M; Honda, M; Kuramochi, T; Mansoor, AM; Morioka, S; Tanaka, K	1
Tuder, R; Voelkel, NF	1
Doyle, MP; Martinez, JM; Resta, TC; Russ, RD; Walker, BR	1
Arcot, SS; Gillespie, MN; Lipke, DW; Olson, JW	1
Bhatti, T; Cathapermal, S; Chen, MF; Farhat, MY; Iqbal, A; Ramwell, PW	1
Kikuchi, K; Mori, C; Ohie, T; Watanabe, K	1
Goto, K; Miyauchi, T; Nishikibe, M; Okada, M; Sakai, S; Sakurai, T; Sugishita, Y; Yamaguchi, I; Yano, M; Yorikane, R	1
Pan, LC; Segall, HJ; Wilson, DW	1
Gewitz, MH; Mathew, R; Tun, H; Zeballos, GA	1
Bachetti, T; Benigno, M; Ceconi, C; Comini, L; Curello, S; Ferrari, R; Gaia, G; Pasini, E	1
Ashino, Y; Fujimura, S; Hoshikawa, Y; Koike, K; Nishimura, T; Noda, M; Ono, S; Tabata, T; Tanita, T; Ueda, S	1
Eguchi, S; Miyamura, H; Sugawara, M; Tatebe, S; Watanabe, H	1
Gewitz, MH; Gloster, ES; Mathew, R; Sundararajan, T; Thompson, CI; Zeballos, GA	1
Anno, T; Honjo, H; Kamiya, K; Kodama, I; Lee, JK; Toyama, J	1
Cernacek, P; Dupuis, J; Leung, TK; Prié, S; Ryan, JW	1
Bernstein, M; Botney, MD; Okada, K; Patterson, GA; Tanaka, Y; Zhang, W	1
Hill, NS; Klinger, JR; Pietras, L; Warburton, RR	1
Brown, L; Dagger, A; Miller, J; Sernia, C	1
Inoue, M; Iwamoto, A; Kanda, T; Kobayashi, I; Nagai, R; Sumino, H; Takahashi, T	1
Horio, T; Kangawa, K; Matsuo, H; Nishikimi, T; Ohe, T; Takishita, S; Yoshihara, F; Yutani, C	1
Jin, X; Liu, K; Wang, H; Xing, J; Zhang, X	1
Abman, SH; Bloch, KD; McMurtry, IF; Muramatsu, M; Rodman, DM; Stelzner, TJ; Tyler, RC	1
Frasch, HF; Marshall, BE; Marshall, C	1
Jin, X; Wang, HL; Xing, J; Zhang, DR; Zhang, XH	1
Basaraba, RJ; Baybutt, RC; Swamidas, GP	1
Gout, B; Khandoudi, N; Le Dantec, C; Quiniou, MJ; Saïag, B	1
Baybutt, RC; Molteni, A	1
Ambrosio, GB; Libera, LD; Sandri, M; Vescovo, G; Zennaro, R	1
Enomoto, M; Fukuta, Y; Iida, M; Ishii, K; Ishikawa, T; Iwata, H; Iwatsuki, Y; Kiyoshi, A; Nakayama, K	1
Brunner, F	1
Emdad, L; Honjo, H; Kodama, I; Magee, AI; Severs, NJ; Takagishi, Y; Uzzaman, M	1
Chen, LC; Gordon, T; Nadziejko, C; Schlesinger, R	1
Brunner, F; Strömer, H; Wölkart, G	1
Bernocchi, P; Ceconi, C; de Jong, JW; de Jonge, R; Harrison, R; Keijzer, E; Schoemaker, RG; Sharma, HS	1
Irukayama-Tomobe, Y; Miyauchi, T; Sakai, S	1
Goto, K; Miyauchi, T; Sakai, S; Ueno, M; Yamaguchi, I	1
Katzman, NJ; Lai, YL	1
Angelini, A; Battista Ambrosio, G; Dalla Libera, L; Ravara, B; Rossini, K; Sandri, M; Thiene, G; Vescovo, G	1
Kim, CS; Lee, JU; Lee, WJ; Paek, YW; Park, HK; Park, SJ	1
Chakrabarti, S; Chen, L; Feng, Q; Gan, XT; Haist, JV; Karmazyn, M; Lu, X	1
Billiar, TR; Ho, C; Kanno, S; Lee, PC; Wu, YJ	1
Fukui, E; Hatano, S; Hayami, N; Miyake, F; Murakawa, Y; Murayama, M; Nakazawa, K; Nobuoka, S; Omata, M; Yamashita, T	1
Brunner, F; Haleen, S; Wölkart, G	1
Brodde, OE; Dhein, S; Giessler, C; Heinroth-Hoffmann, I; Leineweber, K; Seyfarth, T	1
Chang, D; Gunaydin, S; Hagino, I; Imai, Y; Seo, K; Shinoka, T; Takanashi, Y	1
Cao, C; Cho, KW; Han, JH; Kim, SH; Kim, SZ	1
Baybutt, RC; Brady, H; Molteni, A; Rosales, C	1
Che, DY; Li, WY	1

Reviews

1 review(s) available for monocrotaline and Hypertrophy, Right Ventricular

Article	Year
A review of genetically-driven rodent models of pulmonary hypertension. Vascular pharmacology, 2022, Volume: 144 Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Pulmonary Artery; Rodentia	2022

Other Studies

325 other study(ies) available for monocrotaline and Hypertrophy, Right Ventricular

Article	Year
Thioredoxin system activation is associated with the progression of experimental pulmonary arterial hypertension. Life sciences, 2021, Nov-01, Volume: 284 Topics: Animals; Antioxidants; Apoptosis; Cell Survival; Collagen; Disease Progression; Electrocardiography; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Rats, Wistar; Thioredoxins	2021
Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate. Scientific reports, 2021, 09-09, Volume: 11, Issue:1 Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Hemoglobins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Inositol Phosphates; Male; Monocrotaline; Myocardial Contraction; Rats; Rats, Wistar; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Function, Right	2021
Right-sided heart failure is also associated with transverse tubule remodeling in the left ventricle. American journal of physiology. Heart and circulatory physiology, 2021, 11-01, Volume: 321, Issue:5 Topics: Animals; Calcium Signaling; Disease Models, Animal; Heart Failure; Heart Ventricles; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Male; Membrane Proteins; Monocrotaline; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Sarcomeres; Ventricular Function, Left; Ventricular Function, Right; Ventricular Remodeling	2021
Xbp1s-Ddit3 promotes MCT-induced pulmonary hypertension. Clinical science (London, England : 1979), 2021, 11-12, Volume: 135, Issue:21 Topics: Animals; Apoptosis; Arterial Pressure; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor CHOP; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; X-Box Binding Protein 1	2021
Intermittent Fasting Enhances Right Ventricular Function in Preclinical Pulmonary Arterial Hypertension. Journal of the American Heart Association, 2021, 11-16, Volume: 10, Issue:22 Topics: Animals; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fasting; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right; Ventricular Function, Right	2021
Congestive Hepatopathy Secondary to Right Ventricular Hypertrophy Related to Monocrotaline-Induced Pulmonary Arterial Hypertension. International journal of molecular sciences, 2021, Nov-02, Volume: 22, Issue:21 Topics: Animals; Disease Models, Animal; Hypertrophy, Right Ventricular; Liver Diseases; Male; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Rats, Wistar	2021
Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor. Journal of pharmacological sciences, 2022, Volume: 148, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Pulmonary Artery; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Systole; Vasoconstriction; Ventricular Dysfunction, Right; Ventricular Function, Right	2022
TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats. Vascular pharmacology, 2022, Volume: 145 Topics: Animals; Anti-Inflammatory Agents; Cathepsin B; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Inflammasomes; Inflammation; Monocrotaline; NLR Family, Pyrin Domain-Containing 3 Protein; Phosphodiesterase 5 Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Vascular Remodeling	2022
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension. American journal of respiratory and critical care medicine, 2022, 09-01, Volume: 206, Issue:5 Topics: Animals; Atrial Natriuretic Factor; Cytokine Receptor gp130; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fibrosis; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammasomes; Macrophage Activation; Macrophages; Monocrotaline; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Arterial Hypertension; Rats; Ventricular Dysfunction, Right	2022
Prostaglandin E1 reduces apoptosis and improves the homing of mesenchymal stem cells in pulmonary arterial hypertension by regulating hypoxia-inducible factor 1 alpha. Stem cell research & therapy, 2022, 07-16, Volume: 13, Issue:1 Topics: Alprostadil; Animals; Apoptosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Vascular Endothelial Growth Factor A	2022
Melatonin activates the Mst1-Nrf2 signaling to alleviate cardiac hypertrophy in pulmonary arterial hypertension. European journal of pharmacology, 2022, Oct-15, Volume: 933 Topics: Animals; Antioxidants; Arginine Vasopressin; Cysteine; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Hepatocyte Growth Factor; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Malondialdehyde; Melatonin; Monocrotaline; NF-E2-Related Factor 2; Proto-Oncogene Proteins; Pulmonary Arterial Hypertension; Rats; RNA, Small Interfering; Ventricular Remodeling	2022
Activation of Autophagy Induces Monocrotaline-Induced Pulmonary Arterial Hypertension by FOXM1-Mediated FAK Phosphorylation. Lung, 2022, Volume: 200, Issue:5 Topics: Actins; Animals; Autophagy; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Forkhead Box Protein M1; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Ki-67 Antigen; Monocrotaline; Phosphorylation; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Sprague-Dawley	2022
Characteristics of the right atrial and right ventricular contractility in a model of monocrotaline-induced pulmonary arterial hypertension. Journal of muscle research and cell motility, 2023, Volume: 44, Issue:4 Topics: Animals; Atrial Fibrillation; Disease Models, Animal; Heart Atria; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Arterial Hypertension; Rats	2023
Exploring the involvement of TASK-1 in the control of isolated rat right atrium function from healthy animals and an experimental model of monocrotaline-induced pulmonary hypertension. Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:12 Topics: Animals; Atrial Fibrillation; Heart Atria; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Models, Theoretical; Monocrotaline; Rats; Rats, Wistar	2023
Copaiba oil improves pulmonary nitric oxide bioavailability in monocrotaline-treated rats. Canadian journal of physiology and pharmacology, 2023, Sep-01, Volume: 101, Issue:9 Topics: Animals; Antioxidants; Biological Availability; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Nitric Oxide; Oils, Volatile; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Wistar	2023
Involvement of fatty acid synthase in right ventricle dysfunction in pulmonary hypertension. Experimental cell research, 2019, 10-15, Volume: 383, Issue:2 Topics: 4-Butyrolactone; Animals; Animals, Newborn; Cells, Cultured; Fatty Acid Synthase, Type I; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Ventricular Remodeling	2019
Monocrotaline-induced pulmonary arterial hypertension: Time-course of injury and comparative evaluation of macitentan and Y-27632, a Rho kinase inhibitor. European journal of pharmacology, 2019, Dec-15, Volume: 865 Topics: Amides; Animals; Endothelin Receptor Antagonists; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Male; Monocrotaline; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyridines; Pyrimidines; Rats, Wistar; rho-Associated Kinases; Sulfonamides	2019
Formononetin attenuates monocrotaline‑induced pulmonary arterial hypertension via inhibiting pulmonary vascular remodeling in rats. Molecular medicine reports, 2019, Volume: 20, Issue:6 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Proliferation; Disease Models, Animal; Hemodynamics; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Isoflavones; Lung; Male; MAP Kinase Signaling System; Monocrotaline; Phosphatidylinositol 3-Kinases; Proliferating Cell Nuclear Antigen; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Survival Rate; Vascular Remodeling	2019
Investigational new drug enabling angiotensin oral-delivery studies to attenuate pulmonary hypertension. Biomaterials, 2020, Volume: 233 Topics: Animals; Drugs, Investigational; Female; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptide Fragments; Rats; Rats, Sprague-Dawley	2020
Alginate Oligosaccharide Alleviates Monocrotaline-Induced Pulmonary Hypertension via Anti-Oxidant and Anti-Inflammation Pathways in Rats. International heart journal, 2020, Jan-31, Volume: 61, Issue:1 Topics: Alginates; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertrophy, Right Ventricular; Injections, Intraperitoneal; Male; Malondialdehyde; Monocrotaline; Pulmonary Arterial Hypertension; Random Allocation; Rats; Vascular Remodeling	2020
Pulmonary Hypertension Remodels the Genomic Fabrics of Major Functional Pathways. Genes, 2020, 01-23, Volume: 11, Issue:2 Topics: Animals; Genomics; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction	2020
The SGLT2 inhibitor empagliflozin reduces mortality and prevents progression in experimental pulmonary hypertension. Biochemical and biophysical research communications, 2020, 03-26, Volume: 524, Issue:1 Topics: Animals; Benzhydryl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Fibrosis; Glucosides; Heart Ventricles; Hemodynamics; Humans; Hypertrophy, Right Ventricular; Lung; Male; Models, Animal; Monocrotaline; Mortality; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Risk Assessment; Sodium-Glucose Transporter 2 Inhibitors; Vascular Remodeling	2020
Ursolic Acid Improves Monocrotaline-Induced Right Ventricular Remodeling by Regulating Metabolism. Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:6 Topics: Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Fatty Acids; Fibrosis; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; PPAR alpha; Pulmonary Arterial Hypertension; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid; Ventricular Function, Right; Ventricular Remodeling	2020
TRPM4 Modulates Right Ventricular Remodeling Under Pressure Load Accompanied With Decreased Expression Level. Journal of cardiac failure, 2020, Volume: 26, Issue:7 Topics: Animals; Child; Heart Failure; Humans; Hypertrophy, Right Ventricular; Mice; Monocrotaline; Rats; Rats, Wistar; TRPM Cation Channels; Ventricular Function, Right; Ventricular Remodeling	2020
Chrysin Alleviates Monocrotaline-Induced Pulmonary Hypertension in Rats Through Regulation of Intracellular Calcium Homeostasis in Pulmonary Arterial Smooth Muscle Cells. Journal of cardiovascular pharmacology, 2020, Volume: 75, Issue:6 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Calcium Signaling; Disease Models, Animal; Flavonoids; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Muscle, Smooth, Vascular; Pulmonary Artery; Rats, Sprague-Dawley; TRPC Cation Channels; Vascular Remodeling; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling	2020
NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension. BMC pulmonary medicine, 2020, Apr-06, Volume: 20, Issue:1 Topics: Acetamides; Animals; Antihypertensive Agents; Disease Models, Animal; Heart Ventricles; Hemodynamics; Humans; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrazines; Rats; Rats, Inbred WKY; Receptors, Thromboxane; Sildenafil Citrate; Vascular Remodeling	2020
Contribution of reactive oxygen species via the OXR1 signaling pathway in the pathogenesis of monocrotaline-induced pulmonary arterial hypertension: The protective role of Crocin. Life sciences, 2020, Sep-01, Volume: 256 Topics: Animals; Antioxidants; Carotenoids; Disease Models, Animal; Gene Expression Regulation; Hypertrophy, Right Ventricular; Lipid Peroxidation; Male; Mitochondrial Proteins; Monocrotaline; Oxidative Stress; Pulmonary Arterial Hypertension; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction	2020
Protective effect of nicotinamide and L-arginine against monocrotaline-induced pulmonary hypertension in rats: gender dependence. Pharmacological reports : PR, 2020, Volume: 72, Issue:5 Topics: Animals; Arginine; Female; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Niacinamide; Protective Agents; Pulmonary Artery; Rats; Rats, Wistar	2020
Perillyle alcohol and Quercetin ameliorate monocrotaline-induced pulmonary artery hypertension in rats through PARP1-mediated miR-204 down-regulation and its downstream pathway. BMC complementary medicine and therapies, 2020, Jul-13, Volume: 20, Issue:1 Topics: Animals; Disease Models, Animal; Down-Regulation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Male; MicroRNAs; Monocrotaline; Monoterpenes; NFATC Transcription Factors; Poly (ADP-Ribose) Polymerase-1; Pulmonary Artery; Quercetin; Rats; Rats, Wistar	2020
Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn. Journal of molecular and cellular cardiology, 2020, Volume: 148 Topics: Animals; Cell Proliferation; Eicosapentaenoic Acid; Endothelial Cells; Endothelium, Vascular; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-6; Male; Mesoderm; Monocrotaline; Myocardial Contraction; Myocytes, Smooth Muscle; Phosphorylation; Proto-Oncogene Proteins c-fyn; Pulmonary Artery; Rats, Sprague-Dawley; src-Family Kinases; STAT3 Transcription Factor; Survival Analysis; Transforming Growth Factor beta2; Vasodilation; Ventricular Remodeling	2020
Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. International journal of molecular sciences, 2020, Oct-01, Volume: 21, Issue:19 Topics: Acylation; Adult; Aged; AMP-Activated Protein Kinases; Animals; Cell Line; Cohort Studies; Colchicine; Diabetes Mellitus; Disease Models, Animal; Echocardiography; Gene Expression Regulation; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Hexosamines; Humans; Hypertrophy, Right Ventricular; Male; Metabolome; Middle Aged; Mitochondria; Monocrotaline; Myocytes, Cardiac; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction, Right	2020
Plexiform Lesions in an Experimental Model of Monocrotalin-Induced Pulmonary Arterial Hypertension. Arquivos brasileiros de cardiologia, 2020, Volume: 115, Issue:3 Topics: Animals; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Rats, Wistar	2020
The progression of pulmonary arterial hypertension induced by monocrotaline is characterized by lung nitrosative and oxidative stress, and impaired pulmonary artery reactivity. European journal of pharmacology, 2021, Jan-15, Volume: 891 Topics: Animals; Arterial Pressure; Disease Models, Animal; Disease Progression; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Nitrosative Stress; Oxidative Stress; Pulmonary Arterial Hypertension; Pulmonary Artery; Pulmonary Edema; Rats, Wistar; Receptor, Endothelin A; Time Factors; Vascular Remodeling; Vasodilation	2021
Nanoscale Study of Calcium Handling Remodeling in Right Ventricular Cardiomyocytes Following Pulmonary Hypertension. Hypertension (Dallas, Tex. : 1979), 2021, Volume: 77, Issue:2 Topics: Animals; Calcium; Calcium Signaling; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Vascular Remodeling	2021
Characteristics of inflammation process in monocrotaline-induced pulmonary arterial hypertension in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 133 Topics: Animals; Arterial Pressure; Cytokines; Disease Models, Animal; Hypertrophy, Right Ventricular; Inflammation; Inflammation Mediators; Macrophages; Male; Monocrotaline; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Vascular Remodeling	2021
Evaluation of right coronary vascular dysfunction in severe pulmonary hypertensive rats using synchrotron radiation microangiography. American journal of physiology. Heart and circulatory physiology, 2021, 03-01, Volume: 320, Issue:3 Topics: Animals; Antihypertensive Agents; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Monocrotaline; Predictive Value of Tests; Pulmonary Arterial Hypertension; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Synchrotrons; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling	2021
S-Nitroso-L-Cysteine Ameliorated Pulmonary Hypertension in the MCT-Induced Rats through Anti-ROS and Anti-Inflammatory Pathways. Oxidative medicine and cellular longevity, 2021, Volume: 2021 Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cell Movement; Collagen; Cysteine; Endoplasmic Reticulum Stress; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mitophagy; Monocrotaline; Muscle Contraction; Muscle, Smooth; Oxidative Stress; Phosphorylation; Rats, Sprague-Dawley; Reactive Oxygen Species; S-Nitrosothiols; STAT3 Transcription Factor; Vascular Remodeling; Wound Healing	2021
Soluble guanylate cyclase stimulator, trans-4-methoxy-β-nitrostyrene, has a beneficial effect in monocrotaline-induced pulmonary arterial hypertension in rats. European journal of pharmacology, 2021, Apr-15, Volume: 897 Topics: Animals; Arterioles; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Signal Transduction; Soluble Guanylyl Cyclase; Styrenes; Vascular Remodeling; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling	2021
Bmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension. BMC pulmonary medicine, 2021, Mar-05, Volume: 21, Issue:1 Topics: Adventitia; Animals; Cell Line; Cell Proliferation; Cellular Senescence; Disease Models, Animal; Fibroblasts; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Monocrotaline; Polycomb Repressive Complex 1; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction	2021
Quercetin, Perillyl Alcohol, and Berberine Ameliorate Right Ventricular Disorders in Experimental Pulmonary Arterial Hypertension: Effects on miR-204, miR-27a, Fibrotic, Apoptotic, and Inflammatory Factors. Journal of cardiovascular pharmacology, 2021, 06-01, Volume: 77, Issue:6 Topics: Animals; Antioxidants; Apoptosis; Berberine; Disease Models, Animal; Fibrosis; Hypertrophy, Right Ventricular; Male; MicroRNAs; Monocrotaline; Monoterpenes; Pulmonary Arterial Hypertension; Quercetin; Rats; Rats, Wistar; Ventricular Function, Right	2021
Chronic and moderate consumption of reduced-alcohol wine confers cardiac benefits in a rat model of pulmonary arterial hypertension. BMC research notes, 2021, Aug-23, Volume: 14, Issue:1 Topics: Animals; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Wine	2021
Optimal Dose and Timing of Umbilical Stem Cells Treatment in Pulmonary Arterial Hypertensive Rats. Yonsei medical journal, 2017, Volume: 58, Issue:3 Topics: Animals; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Time Factors	2017
Expression profile of matricellular proteins in hypertrophied right ventricle of monocrotaline-induced pulmonary hypertensive rats. The Journal of veterinary medical science, 2017, Jun-29, Volume: 79, Issue:6 Topics: Animals; CCN Intercellular Signaling Proteins; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Transcriptome	2017
Valsartan attenuates pulmonary hypertension via suppression of mitogen activated protein kinase signaling and matrix metalloproteinase expression in rodents. Molecular medicine reports, 2017, Volume: 16, Issue:2 Topics: Animals; Blood Pressure; Cell Proliferation; Extracellular Matrix; Fibrosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Monocrotaline; Phosphorylation; Rats, Sprague-Dawley; Systole; Transforming Growth Factor beta1; Valsartan; Vascular Remodeling	2017
Preventive treatment with atorvastatin ameliorates endothelial dysfunction of small pulmonary arteries in monocrotaline-induced pulmonary hypertensive rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:6 Topics: Animals; Atorvastatin; Endothelium; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Sprague-Dawley; Vasodilation	2017
Preserved right ventricular integrity in a new telemetric rat model of severe pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology, 2017, Nov-01, Volume: 313, Issue:5 Topics: Animals; Disease Models, Animal; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Pulmonary Artery; Rats, Sprague-Dawley; Ventricular Function, Right	2017
Mechanisms of N‑acetylcysteine in reducing monocrotaline‑induced pulmonary hypertension in rats: Inhibiting the expression of Nox1 in pulmonary vascular smooth muscle cells. Molecular medicine reports, 2017, Volume: 16, Issue:5 Topics: Acetylcysteine; Animals; Apoptosis; Cell Proliferation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidase 1; Pulmonary Artery; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Vascular Remodeling	2017
Diethylcarbamazine: A potential treatment drug for pulmonary hypertension? Toxicology and applied pharmacology, 2017, 10-15, Volume: 333 Topics: Actins; Animals; Apoptosis; Apoptosis Regulatory Proteins; Bone Morphogenetic Protein Receptors, Type II; Collagen Type I; Diethylcarbamazine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mice, Inbred C57BL; Monocrotaline; Pulmonary Artery; Ventricular Function, Left	2017
Dihydromyricetin prevents monocrotaline-induced pulmonary arterial hypertension in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 96 Topics: Animals; Disease Models, Animal; Flavonols; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Vascular Remodeling	2017
Reversal effects of low-dose imatinib compared with sunitinib on monocrotaline-induced pulmonary and right ventricular remodeling in rats. Vascular pharmacology, 2018, Volume: 100 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Indoles; Male; Monocrotaline; Nestin; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Pulmonary Artery; Pyrroles; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling	2018
Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting vascular remodeling in rats. Pulmonary pharmacology & therapeutics, 2018, Volume: 48 Topics: Animals; Antioxidants; Apoptosis; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Flavanones; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Male; MAP Kinase Signaling System; Monocrotaline; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vascular Remodeling	2018
Calcium mishandling impairs contraction in right ventricular hypertrophy prior to overt heart failure. Pflugers Archiv : European journal of physiology, 2018, Volume: 470, Issue:7 Topics: Animals; Calcium; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isoproterenol; Male; Monocrotaline; Myocardial Contraction; Rats; Rats, Wistar; Sarcoplasmic Reticulum	2018
Cardioprotective effect of cerium oxide nanoparticles in monocrotaline rat model of pulmonary hypertension: A possible implication of endothelin-1. Life sciences, 2018, May-15, Volume: 201 Topics: Animals; Apoptosis; Cardiotonic Agents; Cerium; Electrocardiography; Endothelin-1; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nanoparticles; Nucleosides; Organ Size; Oxidative Stress; Poisons; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Triazoles	2018
Betaine Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibiting Inflammatory Response. Molecules (Basel, Switzerland), 2018, May-26, Volume: 23, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betaine; Biomarkers; Chemokine CCL2; Cytokines; Disease Models, Animal; Endothelin-1; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Inflammation Mediators; Male; Monocrotaline; Myocardium; NF-kappa B; Pulmonary Artery; Rats	2018
Pulmonary Artery Hypertension Model in Rats by Monocrotaline Administration. Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1816 Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Dysfunction, Right	2018
Activation of AMPK prevents monocrotaline-induced pulmonary arterial hypertension by suppression of NF-κB-mediated autophagy activation. Life sciences, 2018, Sep-01, Volume: 208 Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Disease Models, Animal; Enzyme Activation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; NF-kappa B; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling	2018
Effects of toceranib compared with sorafenib on monocrotaline-induced pulmonary arterial hypertension and cardiopulmonary remodeling in rats. Vascular pharmacology, 2018, Volume: 110 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Autophagy; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Monocrotaline; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pulmonary Artery; Pyrroles; Rats, Wistar; Signal Transduction; Sorafenib; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling	2018
Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats. BMC pulmonary medicine, 2018, Aug-07, Volume: 18, Issue:1 Topics: Animals; Cell Proliferation; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction	2018
Pulmonary arterial hypertension induced by a novel method: Twice-intraperitoneal injection of monocrotaline. Experimental biology and medicine (Maywood, N.J.), 2018, Volume: 243, Issue:12 Topics: Animals; Cardiac Output; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Injections, Intraperitoneal; Interleukin-6; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha	2018
Copaiba Oil Attenuates Right Ventricular Remodeling by Decreasing Myocardial Apoptotic Signaling in Monocrotaline-Induced Rats. Journal of cardiovascular pharmacology, 2018, Volume: 72, Issue:5 Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cardiovascular Agents; Disease Models, Animal; Fabaceae; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; JNK Mitogen-Activated Protein Kinases; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Oils; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar; Signal Transduction; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling	2018
Effects of Beet Juice Supplementation on Monocrotaline-Induced Pulmonary Hypertension in Rats. American journal of hypertension, 2019, 01-15, Volume: 32, Issue:2 Topics: Animals; Arterial Pressure; Beta vulgaris; Dietary Supplements; Disease Models, Animal; Fruit and Vegetable Juices; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide; Plant Roots; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right	2019
17β-estradiol preserves right ventricular function in rats with pulmonary arterial hypertension: an echocardiographic and histochemical study. The international journal of cardiovascular imaging, 2019, Volume: 35, Issue:3 Topics: Animals; Biomarkers; Disease Models, Animal; Echocardiography; Estradiol; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Natriuretic Peptide, Brain; Rats, Sprague-Dawley; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling	2019
Proteinase-activated receptor 1 antagonism ameliorates experimental pulmonary hypertension. Cardiovascular research, 2019, 07-01, Volume: 115, Issue:8 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imines; Male; Mice, Knockout; Monocrotaline; Pulmonary Artery; Pyridines; Rats, Sprague-Dawley; Receptor, PAR-1; Thrombin; Vascular Remodeling; Ventricular Function, Left; Ventricular Remodeling	2019
Eulophia macrobulbon extract relaxes rat isolated pulmonary artery and protects against monocrotaline-induced pulmonary arterial hypertension. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Nov-15, Volume: 50 Topics: Animals; Calcium; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Orchidaceae; Plant Extracts; Plant Tubers; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Thailand; Vasodilation	2018
Exploration of the Notch3-HES5 signal pathway in monocrotaline-induced pulmonary hypertension using rat model. Congenital heart disease, 2019, Volume: 14, Issue:3 Topics: Animals; Arterial Pressure; Arterioles; Basic Helix-Loop-Helix Transcription Factors; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats, Sprague-Dawley; Receptor, Notch3; Repressor Proteins; Signal Transduction; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling	2019
Effect of MiR-21 on pulmonary arterial hypertension via the TGF-β1/Smad2 signal pathway. Minerva medica, 2020, Volume: 111, Issue:2 Topics: Animals; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Hypertension; Hypertrophy, Right Ventricular; Interleukin-1beta; Interleukin-6; Lung; MicroRNAs; Monocrotaline; Myocytes, Smooth Muscle; Pulmonary Arterial Hypertension; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1	2020
NSD2 silencing alleviates pulmonary arterial hypertension by inhibiting trehalose metabolism and autophagy. Clinical science (London, England : 1979), 2019, 05-31, Volume: 133, Issue:9 Topics: Animals; Autophagy; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Hemodynamics; Histone-Lysine N-Methyltransferase; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Vascular Remodeling	2019
[The intervention of ginkgo biloba extract on monocrotaline-induced right ventricular hypertrophy in rats and its mechanism]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2019, Volume: 35, Issue:2 Topics: Animals; Ginkgo biloba; Hypertrophy, Right Ventricular; Male; Monocrotaline; Plant Extracts; Random Allocation; Rats; Rats, Sprague-Dawley	2019
Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model. Scientific reports, 2019, 07-15, Volume: 9, Issue:1 Topics: Animals; Cardiomegaly; Disease Models, Animal; Female; Fibrosis; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Mice; Mice, Inbred C57BL; Monocrotaline; Muscle, Skeletal; Pulmonary Arterial Hypertension; Pulmonary Artery; Vascular Remodeling; Ventricular Function, Right	2019
Combination therapy improves vascular volume in female rats with pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology, 2019, 10-01, Volume: 317, Issue:4 Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Female; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Phenylpropionates; Pneumonectomy; Pulmonary Artery; Pyridazines; Rats; Rats, Sprague-Dawley; Tadalafil; Vascular Remodeling; Vasoconstriction; Ventricular Dysfunction, Right; X-Ray Microtomography	2019
A lymphocyte-dependent mode of action for imatinib mesylate in experimental pulmonary hypertension. The American journal of pathology, 2013, Volume: 182, Issue:5 Topics: Animals; Apoptosis; Benzamides; Cytokines; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Immunomodulation; Leukocyte Count; Lymphocyte Depletion; Lymphocytes; Male; Monocrotaline; Myocytes, Cardiac; Piperazines; Pyrimidines; Rats; Rats, Inbred F344; Rats, Nude	2013
Critical role for the advanced glycation end-products receptor in pulmonary arterial hypertension etiology. Journal of the American Heart Association, 2013, Jan-16, Volume: 2, Issue:1 Topics: Adult; Aged; Animals; Apoptosis; Arterial Pressure; Bone Morphogenetic Protein Receptors, Type II; Case-Control Studies; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Female; Glycation End Products, Advanced; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Middle Aged; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA Interference; S100 Proteins; Signal Transduction; STAT3 Transcription Factor; Transfection; Up-Regulation	2013
Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline-induced pulmonary hypertension in rats. British journal of pharmacology, 2013, Volume: 169, Issue:5 Topics: Adenosine A2 Receptor Agonists; Administration, Oral; Animals; Benzamides; Collagen; Endothelium, Vascular; Hemodynamics; Hydrazones; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Molecular Docking Simulation; Monocrotaline; Pulmonary Artery; Rats, Wistar; Receptors, Adenosine A2	2013
Pyrrolidine dithiocarbamate attenuates the development of monocrotaline-induced pulmonary arterial hypertension. Pathology, research and practice, 2013, Volume: 209, Issue:5 Topics: Animals; Antioxidants; Disease Models, Animal; Endothelium, Vascular; Erythrocytes; Familial Primary Pulmonary Hypertension; Hematocrit; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Malondialdehyde; Monocrotaline; Pyrrolidines; Rats; Rats, Sprague-Dawley; Thiocarbamates	2013
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats. Lung, 2013, Volume: 191, Issue:4 Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Cytoprotection; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Naphthalenes; Neointima; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Resorcinols; Severity of Illness Index; Time Factors; Vasodilation	2013
Impact of dietary iron restriction on the development of monocrotaline-induced pulmonary vascular remodeling and right ventricular failure in rats. Biochemical and biophysical research communications, 2013, Jun-28, Volume: 436, Issue:2 Topics: Animals; Antimicrobial Cationic Peptides; Gene Expression; Hepcidins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Iron, Dietary; Kaplan-Meier Estimate; Lung; Male; Monocrotaline; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Transferrin; Reverse Transcriptase Polymerase Chain Reaction; Ventricular Dysfunction, Right; Ventricular Function, Right	2013
Distinct loading conditions reveal various patterns of right ventricular adaptation. American journal of physiology. Heart and circulatory physiology, 2013, Aug-01, Volume: 305, Issue:3 Topics: Adaptation, Physiological; Animals; Arteriovenous Shunt, Surgical; Constriction; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Models, Cardiovascular; Monocrotaline; Myocardial Contraction; Physical Exertion; Pulmonary Artery; Rats; Rats, Wistar; Stroke Volume; Time Factors; Ultrasonography; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure	2013
Down-regulation of TRPM8 in pulmonary arteries of pulmonary hypertensive rats. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 31, Issue:6 Topics: Animals; Cations; Down-Regulation; Fura-2; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Manganese; Menthol; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; TRPM Cation Channels; Vasodilation	2013
Effect of thrombomodulin on the development of monocrotaline-induced pulmonary hypertension. Journal of anesthesia, 2014, Volume: 28, Issue:1 Topics: Animals; Antithrombin III; Blotting, Western; Chemokine CCL2; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kaplan-Meier Estimate; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Peptide Hydrolases; Rats; Rats, Sprague-Dawley; Thrombomodulin	2014
The effects of gender difference on monocrotaline-induced pulmonary hypertension in rats. Human & experimental toxicology, 2013, Volume: 32, Issue:7 Topics: Animals; Catalase; Female; Glutathione; Glutathione Transferase; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Liver; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sex Characteristics; Superoxide Dismutase; Ventricular Pressure	2013
Endothelial-like progenitor cells engineered to produce prostacyclin rescue monocrotaline-induced pulmonary arterial hypertension and provide right ventricle benefits. Circulation, 2013, Aug-27, Volume: 128, Issue:9 Topics: Animals; Cyclooxygenase 1; Cytochrome P-450 Enzyme System; Disease Models, Animal; Endothelial Cells; Epoprostenol; Familial Primary Pulmonary Hypertension; Genetic Therapy; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infusions, Intravenous; Intramolecular Oxidoreductases; Male; Monocrotaline; Rats; Rats, Inbred F344; Stem Cell Transplantation; Survival Rate; Tissue Engineering; Transfection; Treatment Outcome	2013
Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice. Cardiovascular research, 2013, Dec-01, Volume: 100, Issue:3 Topics: Animals; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiation; Cell Lineage; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Mice; Mice, Inbred C57BL; MicroRNAs; Monocrotaline; Phenotype; RNA, Messenger; Stem Cells; Time Factors; Transport Vesicles	2013
Protection of oral hydrogen water as an antioxidant on pulmonary hypertension. Molecular biology reports, 2013, Volume: 40, Issue:9 Topics: Administration, Oral; Analysis of Variance; Animals; Antioxidants; Atrial Natriuretic Factor; Blood Pressure; Blotting, Western; Hydrogen; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Intercellular Adhesion Molecule-1; Models, Animal; Monocrotaline; Rats	2013
Imatinib attenuates monocrotaline pulmonary hypertension and has potent vasodilator activity in pulmonary and systemic vascular beds in the rat. American journal of physiology. Heart and circulatory physiology, 2013, Nov-01, Volume: 305, Issue:9 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Benzamides; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Muscle, Smooth, Vascular; Phosphodiesterase 4 Inhibitors; Piperazines; Potassium Channel Blockers; Protein Kinase Inhibitors; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Vasoconstriction; Vasodilation; Vasodilator Agents	2013
Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice. Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:2 Topics: Animals; Blotting, Western; Calcium; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mice; Mice, Inbred C57BL; Monocrotaline; Myocardium; Poisons; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Calcium-Sensing	2014
Single intraperitoneal injection of monocrotaline as a novel large animal model of chronic pulmonary hypertension in Tibet minipigs. PloS one, 2013, Volume: 8, Issue:11 Topics: Animals; Disease Models, Animal; Echocardiography; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Pulmonary Artery; Swine; Swine, Miniature	2013
[Inhibitory effect of nitric oxide-induced total ginsenosides on right ventricular hypertrophy in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2013, Volume: 38, Issue:19 Topics: Animals; Ginsenosides; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley	2013
Inhibition of nuclear factor-κB in the lungs prevents monocrotaline-induced pulmonary hypertension in mice. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:6 Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Cell Nucleus; Cytokines; Endothelial Cells; Gene Expression; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; I-kappa B Proteins; Lung; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Monocrotaline; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Receptor, Notch3; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factor RelA	2014
N-acylhydrazone derivative ameliorates monocrotaline-induced pulmonary hypertension through the modulation of adenosine AA2R activity. International journal of cardiology, 2014, May-01, Volume: 173, Issue:2 Topics: Adenosine A2 Receptor Agonists; Animals; Benzamides; Exercise Tolerance; Hydrazones; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats, Wistar; Receptor, Adenosine A2A; Ultrasonography; Vasodilation	2014
Concurrent rho-kinase and tyrosine kinase platelet-derived growth factor inhibition in experimental pulmonary hypertension. Pharmacology, 2014, Volume: 93, Issue:3-4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Becaplermin; Benzamides; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Rats, Wistar; Receptors, Platelet-Derived Growth Factor; rho-Associated Kinases; Ventricular Pressure	2014
Targeted delivery of pulmonary arterial endothelial cells overexpressing interleukin-8 receptors attenuates monocrotaline-induced pulmonary vascular remodeling. Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:7 Topics: Adenoviridae; Animals; Arterial Pressure; Cells, Cultured; Chemokine CCL2; Chemokines, CXC; Disease Models, Animal; Endothelial Cells; Familial Primary Pulmonary Hypertension; Female; Genetic Therapy; Genetic Vectors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Macrophages; Monocrotaline; Neutrophil Infiltration; Neutrophils; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovariectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-8; Transduction, Genetic; Up-Regulation; Ventricular Function, Right; Ventricular Remodeling	2014
Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension. Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:7 Topics: Adult; Aged, 80 and over; Animals; Antihypertensive Agents; Case-Control Studies; Cell Hypoxia; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Enzyme Inhibitors; Familial Primary Pulmonary Hypertension; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Isoenzymes; Male; Mice; Middle Aged; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein-Lysine 6-Oxidase; Pulmonary Artery; Rats; RNA, Messenger; Ventricular Dysfunction, Right; Young Adult	2014
Endothelial nitric oxide synthase-enhancing G-protein coupled receptor antagonist inhibits pulmonary artery hypertension by endothelin-1-dependent and endothelin-1-independent pathways in a monocrotaline model. The Kaohsiung journal of medical sciences, 2014, Volume: 30, Issue:6 Topics: Animals; Blood Pressure; Body Weight; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Endothelin-1; Guanylate Cyclase; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Nitric Oxide Synthase Type III; Piperazines; Piperidines; Pulmonary Artery; Purines; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Sildenafil Citrate; Soluble Guanylyl Cyclase; Sulfonamides; Vasoconstriction; Xanthines	2014
Role of VPAC2 receptor in monocrotaline-induced pulmonary hypertension in rats. Journal of applied physiology (Bethesda, Md. : 1985), 2014, Aug-15, Volume: 117, Issue:4 Topics: Animals; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Ligands; Male; Monocrotaline; Pituitary Adenylate Cyclase-Activating Polypeptide; Poisons; Rats; Rats, Sprague-Dawley; Receptors, Vasoactive Intestinal Peptide, Type II; Receptors, Vasoactive Intestinal Polypeptide, Type I; Vasoactive Intestinal Peptide	2014
NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling. Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:8 Topics: Adventitia; Animals; Antihypertensive Agents; Cell Movement; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Matrix; Familial Primary Pulmonary Hypertension; Fibroblasts; HEK293 Cells; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Mice; Mice, Inbred C57BL; Monocrotaline; NADPH Oxidase 4; NADPH Oxidases; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Time Factors; Transfection; Up-Regulation	2014
HMGB1 promotes the development of pulmonary arterial hypertension in rats. PloS one, 2014, Volume: 9, Issue:7 Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CCL2; Disease Models, Animal; DNA-Binding Proteins; Endothelin-1; Hemodynamics; HMGB1 Protein; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Interleukin-1beta; Male; Monocrotaline; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vascular Resistance; Ventricular Dysfunction, Right	2014
Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension. Cardiovascular research, 2014, Oct-01, Volume: 104, Issue:1 Topics: Acetanilides; Animals; Calcium Signaling; Collagen; Disease Models, Animal; Fibrosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Membrane Potentials; Monocrotaline; Myocytes, Cardiac; Myosin Heavy Chains; Piperazines; Pulmonary Artery; Ranolazine; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Sodium Channels; Time Factors; Vascular Remodeling; Vascular Resistance; Ventricular Function, Right; Ventricular Remodeling	2014
Cerium oxide nanoparticles attenuate monocrotaline induced right ventricular hypertrophy following pulmonary arterial hypertension. Biomaterials, 2014, Volume: 35, Issue:37 Topics: Animals; Antioxidants; Cerium; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nanoparticles; Rats; Rats, Sprague-Dawley	2014
A novel ACE2 activator reduces monocrotaline-induced pulmonary hypertension by suppressing the JAK/STAT and TGF-β cascades with restored caveolin-1 expression. Experimental lung research, 2015, Volume: 41, Issue:1 Topics: Angiotensin-Converting Enzyme 2; Animals; Caveolin 1; Drug Evaluation, Preclinical; Enzyme Activation; Feedback, Physiological; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Janus Kinases; Male; Monocrotaline; Oxazoles; Peptidyl-Dipeptidase A; Pyrimidines; Rats, Sprague-Dawley; STAT Transcription Factors; Transforming Growth Factor beta	2015
Rosuvastatin, sildenafil and their combination in monocrotaline-induced pulmonary hypertension in rat. Acta pharmaceutica (Zagreb, Croatia), 2014, Volume: 64, Issue:3 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Biomarkers; Cholesterol, HDL; Disease Models, Animal; Drug Therapy, Combination; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Natriuretic Peptide, Brain; Phosphodiesterase 5 Inhibitors; Piperazines; Pulmonary Artery; Purines; Pyrimidines; Rats, Wistar; Rosuvastatin Calcium; Sildenafil Citrate; Sulfonamides; Time Factors; Vascular Endothelial Growth Factor A; Vascular Remodeling; Vasodilator Agents; Ventricular Function, Right; Ventricular Pressure	2014
Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension. Circulation, 2015, Jan-13, Volume: 131, Issue:2 Topics: Animals; Apelin; Arterioles; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelial Cells; Fibroblast Growth Factor 2; Hemodynamics; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Intercellular Signaling Peptides and Proteins; Male; MEF2 Transcription Factors; MicroRNAs; Monocrotaline; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Transcription, Genetic	2015
Sex differences in stretch-dependent effects on tension and Ca(2+) transient of rat trabeculae in monocrotaline pulmonary hypertension. The journal of physiological sciences : JPS, 2015, Volume: 65, Issue:1 Topics: Animals; Calcium Signaling; Disease Models, Animal; Endothelium, Vascular; Female; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Pulmonary Veins; Rats; Rats, Wistar; Sex Characteristics	2015
Thymosin Beta 4 protects mice from monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. PloS one, 2014, Volume: 9, Issue:11 Topics: Animals; Cells, Cultured; Collagen Type III; Connective Tissue Growth Factor; Disease Models, Animal; Endothelial Cells; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Intraperitoneal; Lung; Male; Mice; Monocrotaline; Receptor, Notch3; Receptors, Notch; Signal Transduction; Thymosin	2014
Glycyrrhizin, inhibitor of high mobility group box-1, attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling in rats. Respiratory research, 2014, Nov-25, Volume: 15 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Glycyrrhizic Acid; HMGB1 Protein; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Muscle, Smooth, Vascular; Pneumonia; Pulmonary Artery; Rats, Sprague-Dawley; Time Factors; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right	2014
Poly (ADP-ribose) polymerase-1: an emerging target in right ventricle dysfunction associated with pulmonary hypertension. Pulmonary pharmacology & therapeutics, 2015, Volume: 30 Topics: Adenosine Triphosphate; Animals; Apoptosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Isoquinolines; Male; Mitochondria; Mitochondrial Membranes; Monocrotaline; NAD; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-2; Ventricular Dysfunction, Right	2015
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis. British journal of pharmacology, 2015, Volume: 172, Issue:9 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling	2015
HMG-COA reductase inhibitors: An opportunity for the improvement of imatinib safety. An experimental study in rat pulmonary hypertension. Pharmacological reports : PR, 2015, Volume: 67, Issue:1 Topics: Animals; Drug Synergism; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Organ Size; Rats; Rats, Wistar; Rosuvastatin Calcium; Simvastatin	2015
Pathophysiology of infantile pulmonary arterial hypertension induced by monocrotaline. Pediatric cardiology, 2015, Volume: 36, Issue:5 Topics: Animals; Animals, Newborn; Collagen Type I; Collagen Type III; Disease Models, Animal; Endothelin-1; Female; Heart; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Myocytes, Cardiac; Natriuretic Peptide, Brain; Pyrrolizidine Alkaloids; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Transcription Factors	2015
[Glycoltic metabolism gene changes in left and right ventricles in experimental rat pulmonary arterial hypertension model]. Zhonghua xin xue guan bing za zhi, 2014, Volume: 42, Issue:12 Topics: Animals; Gene Expression; Heart Ventricles; Hemodynamics; Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Rats	2014
Therapeutic efficacy of valproic acid in a combined monocrotaline and chronic hypoxia rat model of severe pulmonary hypertension. PloS one, 2015, Volume: 10, Issue:1 Topics: Animals; Blood Pressure; Disease Models, Animal; Hemodynamics; Histone Deacetylase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Valproic Acid	2015
Calorie Restriction Attenuates Monocrotaline-induced Pulmonary Arterial Hypertension in Rats. Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6 Topics: Acetylation; Adenoviridae; Animals; Arterial Pressure; Caloric Restriction; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Genetic Vectors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; Time Factors; Transduction, Genetic; Vascular Remodeling; Vasodilation; Vasodilator Agents	2015
Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: mitochondrial inhibition as driver of cardiac failure? Respiratory research, 2015, Feb-03, Volume: 16 Topics: Administration, Inhalation; Animals; Arterial Pressure; Cardiotonic Agents; Disease Models, Animal; Disease Progression; Dobutamine; Energy Metabolism; Heart Failure; Hexokinase; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; Monocrotaline; Oxygen; Oxygen Consumption; Protoporphyrins; Pulmonary Artery; Rats, Wistar; Ventricular Dysfunction, Right; Ventricular Function, Right	2015
[Total ginsenosides fought against right ventricular hypertrophy through inhibiting calcineurin signal pathway]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2015, Volume: 35, Issue:1 Topics: Animals; Atrial Natriuretic Factor; Calcineurin; Calcineurin Inhibitors; Ginsenosides; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction	2015
Effects of Single Drug and Combined Short-term Administration of Sildenafil, Pimobendan, and Nicorandil on Right Ventricular Function in Rats With Monocrotaline-induced Pulmonary Hypertension. Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6 Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nicorandil; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 5 Inhibitors; Pyridazines; Rats, Wistar; Recovery of Function; Severity of Illness Index; Sildenafil Citrate; Vasodilator Agents; Ventricular Dysfunction, Right; Ventricular Function, Right	2015
Novel assessment of haemodynamic kinetics with acute exercise in a rat model of pulmonary arterial hypertension. Experimental physiology, 2015, Volume: 100, Issue:6 Topics: Animals; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Disease Models, Animal; Enzyme Activation; Exercise Therapy; Glycolysis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kinetics; Male; Monocrotaline; Muscle, Skeletal; Myocardium; Nitric Oxide Synthase Type III; Predictive Value of Tests; Pulmonary Artery; Rats, Sprague-Dawley; Telemetry; Ventricular Function, Right; Ventricular Pressure	2015
Aerobic Exercise Promotes a Decrease in Right Ventricle Apoptotic Proteins in Experimental Cor Pulmonale. Journal of cardiovascular pharmacology, 2015, Volume: 66, Issue:3 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Disease Models, Animal; Echocardiography; Hemodynamics; Hydrogen Peroxide; Hypertrophy, Right Ventricular; Male; Monocrotaline; Physical Conditioning, Animal; Pulmonary Artery; Pulmonary Heart Disease; Rats, Wistar; Vascular Resistance; Ventricular Function, Right; Ventricular Remodeling	2015
The Effect of Umbilical Cord Blood Derived Mesenchymal Stem Cells in Monocrotaline-induced Pulmonary Artery Hypertension Rats. Journal of Korean medical science, 2015, Volume: 30, Issue:5 Topics: Animals; Cytokines; Disease Models, Animal; Endothelin-1; Fetal Blood; Gene Expression Regulation; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Matrix Metalloproteinase 2; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A	2015
miR-223 reverses experimental pulmonary arterial hypertension. American journal of physiology. Cell physiology, 2015, Sep-15, Volume: 309, Issue:6 Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; DNA Damage; Down-Regulation; Female; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Lung; Male; MicroRNAs; Middle Aged; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction	2015
Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats. PloS one, 2015, Volume: 10, Issue:6 Topics: Animals; Apoptosis; Benzothiazoles; Cell Proliferation; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Rats; Rats, Wistar; Toluene; Tumor Suppressor Protein p53	2015
Melatonin as a preventive and curative therapy against pulmonary hypertension. Journal of pineal research, 2015, Volume: 59, Issue:3 Topics: Animals; Antioxidants; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Melatonin; Monocrotaline; Rats; Rats, Long-Evans; Ventricular Dysfunction, Right	2015
Inhibition of Notch3 prevents monocrotaline-induced pulmonary arterial hypertension. Experimental lung research, 2015, Volume: 41, Issue:8 Topics: Animals; Cell Proliferation; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Notch3; Receptors, Notch; Signal Transduction	2015
Influence of imatinib at a low dose and sildenafil on pulmonary hypertension in rats. Die Pharmazie, 2015, Volume: 70, Issue:7 Topics: Animals; Blood Pressure; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Male; Monocrotaline; Protein Kinase Inhibitors; Rats; Rats, Wistar; Sildenafil Citrate; Vasodilator Agents	2015
Farnesoid-X-receptor expression in monocrotaline-induced pulmonary arterial hypertension and right heart failure. Biochemical and biophysical research communications, 2015, Nov-06, Volume: 467, Issue:1 Topics: Animals; Disease Models, Animal; Gene Expression; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Vascular Remodeling; Ventricular Remodeling	2015
Role of miR206 in genistein-induced rescue of pulmonary hypertension in monocrotaline model. Journal of applied physiology (Bethesda, Md. : 1985), 2015, Dec-15, Volume: 119, Issue:12 Topics: Angiogenesis Inducing Agents; Animals; Capillaries; Electrocardiography; Gene Knockdown Techniques; Genistein; Heart Function Tests; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; MicroRNAs; Monocrotaline; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Vascular Endothelial Growth Factor A	2015
Tetrandrine prevents monocrotaline-induced pulmonary arterial hypertension in rats through regulation of the protein expression of inducible nitric oxide synthase and cyclic guanosine monophosphate-dependent protein kinase type 1. Journal of vascular surgery, 2016, Volume: 64, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Arterial Pressure; Benzylisoquinolines; Catalase; Cell Proliferation; Cyclic GMP-Dependent Protein Kinase Type I; Disease Models, Animal; Glutathione; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Malondialdehyde; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Oxidative Stress; Pulmonary Artery; Rats, Sprague-Dawley; Signal Transduction; Superoxide Dismutase; Time Factors; Vascular Remodeling; Ventricular Remodeling	2016
A study on the involvement of GABA-transaminase in MCT induced pulmonary hypertension. Pulmonary pharmacology & therapeutics, 2016, Volume: 36 Topics: 4-Aminobutyrate Transaminase; Animals; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Norepinephrine; Oxidative Stress; Oxygen; Pneumonia; Rats; Rats, Sprague-Dawley; Survival Analysis; Vigabatrin	2016
Aberrant gene expression of heparanase in ventricular hypertrophy induced by monocrotaline in rats. The Journal of veterinary medical science, 2016, Volume: 78, Issue:3 Topics: Animals; Disease Models, Animal; Gene Expression; Glucuronidase; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Rats; Rats, Wistar	2016
Magnetocardiograms early detection of pulmonary arterial hypertension using inverse problem analysis in rat model. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2015, Volume: 2015 Topics: Animals; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley	2015
Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension. Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:4 Topics: Animals; Arterial Pressure; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Macrophages, Alveolar; Male; Monocrotaline; Myocytes, Cardiac; Natriuretic Peptide, Brain; Osteopontin; Pioglitazone; PPAR gamma; Pulmonary Artery; Rats, Sprague-Dawley; Thiazolidinediones; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling	2016
Intratracheal Administration of Prostacyclin Analogue-incorporated Nanoparticles Ameliorates the Development of Monocrotaline and Sugen-Hypoxia-induced Pulmonary Arterial Hypertension. Journal of cardiovascular pharmacology, 2016, Volume: 67, Issue:4 Topics: Adolescent; Adult; Animals; Cell Hypoxia; Cell Proliferation; Child; Disease Models, Animal; Drug Delivery Systems; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Smooth Muscle; Nanoparticles; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Time Factors; Young Adult	2016
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to the development of pulmonary arterial hypertension. Journal of molecular and cellular cardiology, 2016, Volume: 91 Topics: Acetophenones; Acetylcysteine; Animals; Apoptosis; Calcium; Calcium Channels, L-Type; Cell Proliferation; Gene Expression Regulation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Metalloporphyrins; Monocrotaline; Myocytes, Smooth Muscle; Organ Culture Techniques; Pentose Phosphate Pathway; Phosphorylation; Primary Cell Culture; Pulmonary Artery; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serine	2016
Therapeutic Benefits of Induced Pluripotent Stem Cells in Monocrotaline-Induced Pulmonary Arterial Hypertension. PloS one, 2016, Volume: 11, Issue:2 Topics: Adult; Animals; Cells, Cultured; Culture Media, Conditioned; Cytokines; Disease Models, Animal; Down-Regulation; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Interferon-gamma; Interleukins; Lung; Macrophages; Male; Monocrotaline; NF-kappa B; Phosphorylation; Pluripotent Stem Cells; Pulmonary Artery; Rats	2016
Protective effects of drag-reducing polymers in a rat model of monocrotaline-induced pulmonary hypertension. Biorheology, 2016, 01-27, Volume: 53, Issue:1 Topics: Animals; Blood Pressure; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-1beta; Interleukin-6; Male; Monocrotaline; Polyethylene Glycols; Polymers; Pulmonary Artery; Rats; Rats, Wistar; Surface-Active Agents	2016
Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension. Circulation, 2016, Apr-05, Volume: 133, Issue:14 Topics: Adventitia; Animals; Bone Morphogenetic Protein Receptors, Type II; Cell Division; Endothelium, Vascular; Fibroblasts; Genetic Predisposition to Disease; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Male; Membrane Potentials; Monocrotaline; Mutation; Myocytes, Smooth Muscle; Nerve Tissue Proteins; ortho-Aminobenzoates; Patch-Clamp Techniques; Potassium Channels, Tandem Pore Domain; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sulfonamides; Vascular Resistance	2016
Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung. PloS one, 2016, Volume: 11, Issue:3 Topics: Animals; Blood Pressure; Carnitine; Disease Models, Animal; Disease Progression; Glutathione; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Metabolic Networks and Pathways; Metabolome; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Time Factors	2016
Exosomes induce and reverse monocrotaline-induced pulmonary hypertension in mice. Cardiovascular research, 2016, 06-01, Volume: 110, Issue:3 Topics: Animals; Case-Control Studies; Cell-Derived Microparticles; Cells, Cultured; Disease Models, Animal; Exosomes; Familial Primary Pulmonary Hypertension; Gene Expression Regulation; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice, Inbred C57BL; MicroRNAs; Monocrotaline; Pulmonary Artery; Vascular Remodeling	2016
Priming with ceramide-1 phosphate promotes the therapeutic effect of mesenchymal stem/stromal cells on pulmonary artery hypertension. Biochemical and biophysical research communications, 2016, Apr-22, Volume: 473, Issue:1 Topics: Animals; Anti-Inflammatory Agents; Cell Movement; Cell Proliferation; Ceramides; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; MAP Kinase Signaling System; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Rats; Rats, Inbred Lew; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells	2016
Endostatin is protective against monocrotaline-induced right heart disease through the inhibition of T-type Ca(2+) channel. Pflugers Archiv : European journal of physiology, 2016, Volume: 468, Issue:7 Topics: Animals; Blood Pressure; Calcium Channels, T-Type; Cell Line; Echocardiography; Endostatins; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Pulmonary Artery; Rats; Rats, Wistar; Systole	2016
Hydroxysafflor yellow A improves established monocrotaline-induced pulmonary arterial hypertension in rats. The Journal of international medical research, 2016, Volume: 44, Issue:3 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Chalcone; Deoxyguanosine; Gene Expression Regulation; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Male; Malondialdehyde; Monocrotaline; Oxidative Stress; Quinones; Rats, Wistar; RNA, Messenger; Superoxide Dismutase; Vascular Remodeling	2016
Preventive aerobic training exerts a cardioprotective effect on rats treated with monocrotaline. International journal of experimental pathology, 2016, Volume: 97, Issue:3 Topics: Aerobiosis; Animals; Cardiotonic Agents; Disease Models, Animal; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Physical Conditioning, Animal; Rats, Wistar	2016
Bortezomib alleviates experimental pulmonary hypertension by regulating intracellular calcium homeostasis in PASMCs. American journal of physiology. Cell physiology, 2016, 09-01, Volume: 311, Issue:3 Topics: Animals; Bone Morphogenetic Protein 4; Bortezomib; Calcium; Calcium Signaling; Cell Hypoxia; Cell Proliferation; Homeostasis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia-Inducible Factor 1, alpha Subunit; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; PPAR gamma; Pulmonary Artery; Rats; Rats, Sprague-Dawley; TRPC Cation Channels; Up-Regulation	2016
Thymoquinone attenuates monocrotaline-induced pulmonary artery hypertension via inhibiting pulmonary arterial remodeling in rats. International journal of cardiology, 2016, Oct-15, Volume: 221 Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction; Treatment Outcome; Vascular Remodeling	2016
Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension. The Journal of steroid biochemistry and molecular biology, 2017, Volume: 165, Issue:Pt B Topics: Animals; Chenodeoxycholic Acid; Exercise Test; Gene Expression Profiling; Gene Expression Regulation; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Lung; Lung Injury; Male; Monocrotaline; Organ Size; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger	2017
Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension. Respiratory research, 2016, 08-31, Volume: 17, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Case-Control Studies; Disease Models, Animal; Disease Progression; Endothelin-1; Epoprostenol; Female; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Liver; Lung; Male; Middle Aged; Monocrotaline; Niacinamide; Nicotinamide N-Methyltransferase; Nitric Oxide; Rats, Wistar; Signal Transduction; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right	2016
A urotensin II receptor antagonist, KR36676, decreases vascular remodeling and inflammation in experimental pulmonary hypertension. International immunopharmacology, 2016, Volume: 40 Topics: Acetamides; Animals; Anti-Inflammatory Agents; Benzoxazines; Collagen; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; MAP Kinase Signaling System; Monocrotaline; NF-kappa B; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha; Vascular Remodeling	2016
Monocrotaline-Induced Pulmonary Hypertension Involves Downregulation of Antiaging Protein Klotho and eNOS Activity. Hypertension (Dallas, Tex. : 1979), 2016, Volume: 68, Issue:5 Topics: Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Down-Regulation; Glucuronidase; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Klotho Proteins; Male; Mesenchymal Stem Cells; Monocrotaline; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Sirtuin 1; Transfection	2016
Cardiac Body Surface Potentials in Rats with Experimental Pulmonary Hypertension during Ventricular Depolarization. Bulletin of experimental biology and medicine, 2016, Volume: 162, Issue:1 Topics: Animals; Blood Pressure; Electrocardiography; Electrodes; Female; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Subcutaneous; Lung; Monocrotaline; Pulmonary Artery; Rats; Rats, Wistar	2016
Aspirin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing the ERK/MAPK pathway. Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:1 Topics: Animals; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Flavonoids; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; MAP Kinase Signaling System; Monocrotaline; Nitric Oxide Synthase Type III; Protein Kinase Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Systole; Vascular Remodeling	2017
Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency. Molecular pharmaceutics, 2017, 03-06, Volume: 14, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arterial Pressure; Chemistry, Pharmaceutical; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Liposomes; Lung; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Superoxide Dismutase; Vasodilator Agents	2017
Let-7a-transfected mesenchymal stem cells ameliorate monocrotaline-induced pulmonary hypertension by suppressing pulmonary artery smooth muscle cell growth through STAT3-BMPR2 signaling. Stem cell research & therapy, 2017, 02-10, Volume: 8, Issue:1 Topics: Adenoviridae; Animals; Bone Morphogenetic Protein Receptors, Type II; Coculture Techniques; Gene Expression Regulation; Genetic Vectors; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; MicroRNAs; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Inbred Lew; Signal Transduction; STAT3 Transcription Factor; Transfection	2017
5-Aminosalicylic Acid Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats by Increasing the Expression of Nur77. Inflammation, 2017, Volume: 40, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mesalamine; Monocrotaline; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction; Survival Rate	2017
Protective effects of aloperine on monocrotaline-induced pulmonary hypertension in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 89 Topics: Animals; Antioxidants; Biomarkers; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Oxidative Stress; Piperidines; Protective Agents; Pulmonary Artery; Pulmonary Circulation; Quinolizidines; Rats; Rats, Sprague-Dawley	2017
Effects of Sevoflurane on Hemodynamics and Inducible Nitric Oxide Synthase/Soluble Guanylate Cyclase Signaling Pathway in a Rat Model of Pulmonary Arterial Hypertension. Anesthesia and analgesia, 2017, Volume: 125, Issue:1 Topics: Animals; Guanylate Cyclase; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Methyl Ethers; Monocrotaline; Nitric Oxide Synthase Type II; Platelet Aggregation Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction; Soluble Guanylyl Cyclase; Ventricular Function, Right	2017
Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat. Naunyn-Schmiedeberg's archives of pharmacology, 2008, Volume: 378, Issue:3 Topics: Acetylcholine; Animals; Atorvastatin; Blotting, Western; Body Weight; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Disease Progression; Drug Combinations; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfonamides; Survival Analysis; Vasodilator Agents	2008
Effects of TNF-alpha blockade in monocrotaline-induced pulmonary hypertension. Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2008, Volume: 27, Issue:3 Topics: Animals; Etanercept; Heart Failure; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunoglobulin G; Male; Monocrotaline; Random Allocation; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha	2008
Total ginsenosides inhibit the right ventricular hypertrophy induced by monocrotaline in rats. Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:8 Topics: Animals; Blood Pressure; Blotting, Western; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Ginsenosides; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mitogen-Activated Protein Kinases; Monocrotaline; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Panax; Poisons; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction	2008
Novel approach with intratracheal administration of microgelatin hydrogel microspheres incorporating basic fibroblast growth factor for rescue of rats with monocrotaline-induced pulmonary hypertension. The Journal of thoracic and cardiovascular surgery, 2008, Volume: 136, Issue:5 Topics: Animals; Blood Gas Analysis; Body Weight; Disease Progression; Fibroblast Growth Factor 2; Gelatin; Hemodynamics; Hydrogels; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Microspheres; Monocrotaline; Rats; Rats, Wistar; Trachea	2008
Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats. Journal of pharmacological sciences, 2008, Volume: 108, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Disease Models, Animal; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Wistar; Ventricular Dysfunction, Right	2008
Molecular and electrical remodeling of L- and T-type Ca(2+) channels in rat right atrium with monocrotaline-induced pulmonary hypertension. Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:2 Topics: Animals; Calcium Channels, L-Type; Calcium Channels, T-Type; Disease Models, Animal; Electrophysiologic Techniques, Cardiac; Heart Atria; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Monocrotaline; Patch-Clamp Techniques; Rats; Rats, Wistar; RNA, Messenger	2009
Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by monocrot The American journal of pathology, 2009, Volume: 174, Issue:2 Topics: Animals; Blotting, Western; Bone Morphogenetic Protein Receptors, Type II; Cell Proliferation; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Image Processing, Computer-Assisted; Imidazoles; Immunohistochemistry; Monocrotaline; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pulmonary Artery; Quinoxalines; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Smad3 Protein; Transforming Growth Factor beta1	2009
Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling. Cardiovascular research, 2009, Apr-01, Volume: 82, Issue:1 Topics: Administration, Oral; Animals; Blood Pressure; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Fibrillar Collagens; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Natriuretic Peptides; Osteopontin; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Rats, Wistar; RNA, Messenger; Sildenafil Citrate; Stroke Volume; Sulfones; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Ventricular Pressure; Ventricular Remodeling	2009
The remodeling of connexin in the hypertrophied right ventricular in pulmonary arterial hypertension and the effect of a dual ET receptor antagonist (bosentan). Pathology, research and practice, 2009, Volume: 205, Issue:7 Topics: Animals; Bosentan; Connexin 43; Disease Models, Animal; Endothelin Receptor Antagonists; Gap Junctions; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microscopy, Confocal; Microscopy, Electron; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Sulfonamides; Ventricular Remodeling	2009
Galphaq-protein carboxyl terminus imitation polypeptide (GCIP)-27 inhibits right ventricular hypertrophy induced by monocrotaline in rats. Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:3 Topics: Animals; GTP-Binding Protein alpha Subunits, Gq-G11; Hemodynamics; Hypertrophy, Right Ventricular; Male; Monocrotaline; Muscle Cells; Myocardium; Peptide Fragments; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley	2009
Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:6 Topics: Angiotensin I; Animals; Antihypertensive Agents; Apelin; Apelin Receptors; Carrier Proteins; Endothelin-1; Gene Expression Profiling; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Intercellular Signaling Peptides and Proteins; Male; Monocrotaline; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger; Ventricular Function, Right	2009
Preventive effects of raloxifene, a selective estrogen receptor modulator, on monocrotaline-induced pulmonary hypertension in intact and ovariectomized female rats. European journal of pharmacology, 2009, Jul-01, Volume: 614, Issue:1-3 Topics: Animals; Blood Pressure; Body Weight; Endothelin-1; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Organ Size; Ovariectomy; Pulmonary Artery; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Substrate Specificity; Time Factors; Ventricular Dysfunction, Right	2009
Resveratrol inhibits right ventricular hypertrophy induced by monocrotaline in rats. Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:2 Topics: Animals; Apoptosis; Cardiotonic Agents; Heart; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes	2010
Propylthiouracil attenuates monocrotaline-induced pulmonary arterial hypertension in rats. Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:9 Topics: Animals; Antihypertensive Agents; Arterioles; Caspase 3; Connexin 43; Disease Models, Animal; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Matrix Metalloproteinase 9; Monocrotaline; Nitric Oxide Synthase Type III; Propylthiouracil; Protein Kinase C-epsilon; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha; Ventricular Function, Right; Ventricular Pressure	2009
Alterations in pharmacological action of the right ventricle of monocrotaline-induced pulmonary hypertensive rats. Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:8 Topics: Animals; Body Weight; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Myocardial Contraction; Organ Size; Perfusion; Rats; Rats, Wistar; Ventricular Function, Right	2009
Pressure overload-induced right ventricular failure is associated with re-expression of myocardial tenascin-C and elevated plasma tenascin-C levels. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2009, Volume: 24, Issue:3-4 Topics: Animals; Blood Pressure; Gene Expression; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Immunohistochemistry; Integrins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Rats; Rats, Wistar; Tenascin; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling	2009
Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension. American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5 Topics: Animals; Arterioles; Cardiac Output; Cell Differentiation; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Extracellular Matrix Proteins; Female; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Lung; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Myocardial Contraction; Myocardium; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Wistar; Recovery of Function; RNA, Messenger; Stroke Volume; Time Factors; Transplantation, Homologous; Vascular Endothelial Growth Factor A; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling	2009
Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats. Journal of pharmacological sciences, 2009, Volume: 111, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Body Weight; Echocardiography; Fibrosis; Histocytochemistry; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Organ Size; Rats; Rats, Wistar; Stroke Volume; Systole; Telmisartan; Transforming Growth Factor beta1; Ventricular Remodeling	2009
Effects of a pure alpha/beta-adrenergic receptor blocker on monocrotaline-induced pulmonary arterial hypertension with right ventricular hypertrophy in rats. Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:12 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Disease Models, Animal; Disease Progression; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Propanolamines; Rats; Rats, Wistar; Sympathetic Nervous System; Ventricular Pressure	2009
Simvastatin restores down-regulated GATA-6 expression in pulmonary hypertensive rats. Experimental lung research, 2009, Volume: 35, Issue:5 Topics: Animals; Blood Pressure; Blotting, Western; Cell Proliferation; Disease Models, Animal; Down-Regulation; GATA6 Transcription Factor; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Time Factors	2009
Alterations in dystrophin-related glycoproteins in development of right ventricular failure in rats. Journal of pharmacological sciences, 2009, Volume: 111, Issue:4 Topics: Animals; Calpain; Dystroglycans; Dystrophin-Associated Protein Complex; Heart Failure; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Monocrotaline; Myocardium; Rats; Rats, Wistar; Sarcoglycans; Time Factors; Ventricular Dysfunction, Right	2009
Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:3 Topics: Animals; Antioxidants; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Organometallic Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Salicylates; Ventricular Dysfunction, Right; Ventricular Remodeling	2010
The extracellular signal-regulated kinase is involved in the effects of sildenafil on pulmonary vascular remodeling. Cardiovascular therapeutics, 2010,Spring, Volume: 28, Issue:1 Topics: Actins; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dual Specificity Phosphatase 1; Fluorescent Antibody Technique; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocrotaline; Phosphorylation; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Sulfones; Vasodilator Agents	2010
Pulmonary hypertension is ameliorated in mice deficient in thrombin-activatable fibrinolysis inhibitor. Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:4 Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Capillary Permeability; Carboxypeptidase B2; Chemokine CCL2; Disease Models, Animal; Fibrinolysis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Interleukin-6; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocrotaline; Platelet-Derived Growth Factor; Pulmonary Artery; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Weight Loss	2010
Gene delivery of cytochrome p450 epoxygenase ameliorates monocrotaline-induced pulmonary artery hypertension in rats. American journal of respiratory cell and molecular biology, 2010, Volume: 43, Issue:6 Topics: 8,11,14-Eicosatrienoic Acid; Animals; Bone Morphogenetic Protein Receptors, Type II; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Endothelial Cells; Gene Transfer Techniques; Genetic Therapy; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-10; Interleukin-6; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Survival Analysis; Tissue Extracts; Transforming Growth Factor beta	2010
Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats. Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Histone Deacetylase Inhibitors; Hypertrophy, Right Ventricular; Ligation; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Valproic Acid	2010
Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil. The European respiratory journal, 2010, Volume: 36, Issue:4 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Familial Primary Pulmonary Hypertension; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Piperazines; Pulmonary Artery; Purines; Rats; Sildenafil Citrate; Sulfonamides; Sulfones; Vasodilator Agents	2010
PRX-08066, a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:2 Topics: Animals; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Magnetic Resonance Imaging; Male; Monocrotaline; Myocardium; Organ Size; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT2 Receptor Antagonists; Thiophenes	2010
Early inflammatory response during the development of right ventricular heart failure in a rat model. European journal of heart failure, 2010, Volume: 12, Issue:7 Topics: Animals; Autoradiography; Disease Models, Animal; Disease Progression; Gallium Radioisotopes; Gene Expression Profiling; Heart Failure; Hypertrophy, Right Ventricular; Immunochemistry; Inflammation; Male; Monocrotaline; Myocardium; Neutrophil Activation; Peroxidase; Radionuclide Imaging; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Right	2010
Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology, 2010, Volume: 299, Issue:3 Topics: Animals; Blood Pressure; Cardiac Catheterization; Cardiac Output; Catheterization; Echocardiography; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Magnetic Resonance Imaging; Male; Monocrotaline; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Thermodilution	2010
Urotensin II receptor antagonist attenuates monocrotaline-induced cardiac hypertrophy in rats. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:6 Topics: Animals; Atrial Function; Atrial Natriuretic Factor; Cardiotonic Agents; Cell Hypoxia; Disease Models, Animal; Humans; Hypertrophy, Right Ventricular; Infusions, Intravenous; Infusions, Subcutaneous; Male; Monocrotaline; Myocardial Contraction; Myocardium; Peptide Fragments; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors; Urotensins; Vasoconstriction; Ventricular Function, Right	2010
Systemic evaluation of platelet and leukocyte activation and interaction in a rat model of pulmonary arterial hypertension. Cardiology, 2010, Volume: 117, Issue:1 Topics: Animals; Cell Communication; Disease Models, Animal; Flow Cytometry; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Leukocytes; Male; Monocrotaline; Platelet Activation; Rats; Rats, Sprague-Dawley	2010
Protective effects of hydrogen-rich saline on monocrotaline-induced pulmonary hypertension in a rat model. Respiratory research, 2011, Mar-04, Volume: 12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Biomarkers; Blood Pressure; Deoxyguanosine; Enzyme-Linked Immunosorbent Assay; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Interleukin-6; Male; Malondialdehyde; Monocrotaline; Rats; Rats, Sprague-Dawley; Sodium Chloride; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha	2011
Treatment of pulmonary arterial hypertension with circulating angiogenic cells. American journal of physiology. Lung cellular and molecular physiology, 2011, Volume: 301, Issue:1 Topics: Animals; Arteries; Cell Movement; Endothelial Cells; Familial Primary Pulmonary Hypertension; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kaplan-Meier Estimate; Monocrotaline; Rats; Rats, Nude; Stem Cell Transplantation; Stem Cells; Ventricular Remodeling	2011
Arrhythmogenic substrate in hearts of rats with monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:6 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channels; Computer Simulation; Disease Models, Animal; Electric Stimulation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Potassium Channels; Rats; Rats, Wistar; Stroke Volume; Tachycardia, Ventricular	2011
Acceleration of Ca2+ waves in monocrotaline-induced right ventricular hypertrophy in the rat. Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:6 Topics: Animals; Arrhythmias, Cardiac; Calcium Signaling; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kinetics; Membrane Potentials; Monocrotaline; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Ventricular Function, Right; Ventricular Pressure	2011
Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats. Respiratory research, 2011, May-02, Volume: 12 Topics: Animals; Cell Degranulation; Cromolyn Sodium; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mast Cells; Monocrotaline; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Ventricular Function, Right; Ventricular Remodeling	2011
Involvement of BMPR2 in the protective effect of fluoxetine against monocrotaline-induced endothelial apoptosis in rats. Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:5 Topics: Animals; Apoptosis; beta Catenin; Blood Pressure; Bone Morphogenetic Protein Receptors, Type II; Caspase 3; Cyclic GMP-Dependent Protein Kinases; Endothelial Cells; Fluoxetine; Gene Expression; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Microvessels; Monocrotaline; Phosphorylation; Pulmonary Artery; Rats; Rats, Wistar; Smad1 Protein	2011
A role for coagulation factor Xa in experimental pulmonary arterial hypertension. Cardiovascular research, 2011, Oct-01, Volume: 92, Issue:1 Topics: Animals; Blood Coagulation; Enoxaparin; Factor Xa; Factor Xa Inhibitors; Familial Primary Pulmonary Hypertension; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Morpholines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rivaroxaban; Thiophenes; Thrombosis; Warfarin	2011
Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension. Respiratory research, 2011, Jun-23, Volume: 12 Topics: Administration, Oral; Animals; Antihypertensive Agents; Disease Models, Animal; Echocardiography, Doppler; Endothelin A Receptor Antagonists; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isoxazoles; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sulfones; Time Factors; Ventricular Function, Right; Ventricular Remodeling	2011
Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:2 Topics: Animals; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung; Male; Mice; Mice, Knockout; Monocrotaline; Mutation; Rats; Superoxide Dismutase	2011
Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats. Hypertension (Dallas, Tex. : 1979), 2011, Volume: 58, Issue:3 Topics: Actins; Animals; Apoptosis; Blotting, Western; Caspase 3; Emulsions; Fat Emulsions, Intravenous; Fibrosis; Heart; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Microscopy, Confocal; Monocrotaline; Myocardium; Phospholipids; Platelet Endothelial Cell Adhesion Molecule-1; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Soybean Oil; Vascular Endothelial Growth Factor A	2011
Simvastatin protects against the development of monocrotaline-induced pulmonary hypertension in rats via a heme oxygenase-1-dependent pathway. Experimental lung research, 2011, Volume: 37, Issue:8 Topics: Animals; Arterioles; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-6; Lung; Monocrotaline; Protoporphyrins; Rats; Rats, Sprague-Dawley; Signal Transduction; Simvastatin	2011
Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension. Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:2 Topics: Animals; Calcium; Disease Models, Animal; Excitation Contraction Coupling; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microscopy, Confocal; Monocrotaline; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Remodeling	2012
Cardiac-specific genetic inhibition of nuclear factor-κB prevents right ventricular hypertrophy induced by monocrotaline. American journal of physiology. Heart and circulatory physiology, 2012, Apr-15, Volume: 302, Issue:8 Topics: Animals; Blotting, Western; Cell Adhesion Molecules; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; I-kappa B Proteins; Inflammation; Male; Mice; Monocrotaline; Myocardium; NF-kappa B; NF-KappaB Inhibitor alpha; Poisons; Real-Time Polymerase Chain Reaction; RNA; Signal Transduction; Ventricular Remodeling	2012
Effects of autologous bone marrow mononuclear cells implantation in canine model of pulmonary hypertension. Circulation journal : official journal of the Japanese Circulation Society, 2012, Volume: 76, Issue:4 Topics: Animals; Bone Marrow Transplantation; Cell Differentiation; Cell Separation; Cell Tracking; Disease Models, Animal; Dogs; Endothelial Cells; Endothelin-1; Flow Cytometry; Fluorescent Antibody Technique; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Interleukin-6; Monocrotaline; Neovascularization, Physiologic; Pulmonary Artery; RNA, Messenger; Stem Cell Transplantation; Time Factors; Transplantation, Autologous; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Ventricular Function, Right	2012
Monocrotaline-induced pulmonary hypertension in Wistar rats. Current protocols in pharmacology, 2009, Volume: Chapter 5 Topics: Animals; Antihypertensive Agents; Cardiac Output; Carotid Arteries; Catheterization, Swan-Ganz; Disease Models, Animal; Femoral Artery; Femoral Vein; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Wedge Pressure; Rats; Rats, Wistar	2009
Cardiac and vascular atrogin-1 mRNA expression is not associated with dexamethasone efficacy in the monocrotaline model of pulmonary hypertension. Cardiovascular toxicology, 2012, Volume: 12, Issue:3 Topics: Animals; Blood Pressure; Dexamethasone; Disease Models, Animal; Drug Antagonism; Gene Expression; Glucocorticoids; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Muscle Proteins; Myostatin; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; SKP Cullin F-Box Protein Ligases	2012
Effect of chronic sodium nitrite therapy on monocrotaline-induced pulmonary hypertension. Nitric oxide : biology and chemistry, 2012, Jun-30, Volume: 27, Issue:1 Topics: Animals; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Morpholines; Nitric Oxide; Nitroprusside; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Tunica Media	2012
Role of Src tyrosine kinases in experimental pulmonary hypertension. Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6 Topics: Animals; Apoptosis; Becaplermin; Benzamides; Cell Proliferation; Cells, Cultured; Chemotaxis; Dasatinib; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imatinib Mesylate; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pyrimidines; Rats; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Thiazoles; Time Factors	2012
Attenuation of monocrotaline-induced pulmonary arterial hypertension in rats by rosuvastatin. Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:2 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Familial Primary Pulmonary Hypertension; Fluorobenzenes; Gene Expression Regulation, Enzymologic; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide Synthase Type III; Proliferating Cell Nuclear Antigen; Pulmonary Artery; Pyrimidines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; RNA, Messenger; Rosuvastatin Calcium; Sulfonamides; Time Factors	2012
Enhanced Ca(2+)-sensing receptor function in idiopathic pulmonary arterial hypertension. Circulation research, 2012, Aug-03, Volume: 111, Issue:4 Topics: Aniline Compounds; Animals; Calcimimetic Agents; Calcium Signaling; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Mice; Mice, Inbred C57BL; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthalenes; Phenethylamines; Propylamines; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing; RNA Interference; Spermine; Time Factors; Transfection; Vasoconstriction	2012
Superiority of desflurane over sevoflurane and isoflurane in the presence of pressure-overload right ventricle hypertrophy in rats. Anesthesiology, 2012, Volume: 117, Issue:5 Topics: Anesthetics, Inhalation; Animals; Desflurane; Hypertrophy, Right Ventricular; Isoflurane; Male; Methyl Ethers; Monocrotaline; Random Allocation; Rats; Rats, Wistar; Sevoflurane	2012
Iptakalim ameliorates monocrotaline-induced pulmonary arterial hypertension in rats. Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:1 Topics: Animals; Endothelin-1; Familial Primary Pulmonary Hypertension; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; KATP Channels; Lung; Male; Monocrotaline; Natriuretic Peptide, Brain; Nitric Oxide; Propylamines; Rats; Rats, Wistar	2013
Additive effect of tadalafil and simvastatin on monocrotaline-induced pulmonary hypertension rats. Scandinavian cardiovascular journal : SCJ, 2012, Volume: 46, Issue:6 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Arterioles; Carbolines; Disease Models, Animal; Drug Therapy, Combination; Familial Primary Pulmonary Hypertension; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Interleukin-6; Male; Monocrotaline; Phosphodiesterase 5 Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Simvastatin; Tadalafil; Time Factors; Vasodilator Agents	2012
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension. American journal of physiology. Cell physiology, 2012, Dec-15, Volume: 303, Issue:12 Topics: Animals; Anoctamin-1; Calcium Channel Blockers; Chloride Channel Agonists; Chloride Channels; Cyclooxygenase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indomethacin; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nifedipine; Niflumic Acid; Patch-Clamp Techniques; Pulmonary Artery; Pyrimidines; Rats; Rats, Wistar; Serotonin; Thiazoles	2012
Urotensin inhibition with palosuran could be a promising alternative in pulmonary arterial hypertension. Inflammation, 2013, Volume: 36, Issue:2 Topics: Animals; Arterial Pressure; Arterioles; Endothelin-1; Familial Primary Pulmonary Hypertension; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Quinolines; Rats; Rats, Wistar; Transforming Growth Factor beta1; Urea; Urotensins	2013
Cardiac modulations of ANG II receptor expression in rats with hypoxic pulmonary hypertension. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:2 Topics: Animals; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Ligands; Male; Monocrotaline; Myocardium; Organ Size; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger	2002
Dexfenfluramine protects against pulmonary hypertension in rats. Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:5 Topics: Animals; Appetite Depressants; Body Weight; Dexfenfluramine; Eating; Endothelium, Vascular; Female; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Nitric Oxide Synthase; Obesity; Organ Size; Pancreatic Elastase; Pulmonary Artery; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vascular Diseases	2002
Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary hypertension in rats. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:5 Topics: Animals; Chemokine CCL2; Electroporation; Gene Expression; Genetic Therapy; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Intramuscular; Macrophages; Male; Monocrotaline; Monocytes; Plasmids; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Rats, Sprague-Dawley; Survival Rate; Transgenes	2002
Simvastatin attenuates smooth muscle neointimal proliferation and pulmonary hypertension in rats. American journal of respiratory and critical care medicine, 2002, Nov-15, Volume: 166, Issue:10 Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organ Size; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Treatment Outcome; Tunica Intima	2002
Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure. Circulation research, 2002, Nov-29, Volume: 91, Issue:11 Topics: Animals; Binding, Competitive; Cell Membrane; Disease Models, Animal; Eye Proteins; Fluoxetine; G-Protein-Coupled Receptor Kinase 1; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Size; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Rhodopsin; Symporters	2002
Skeletal muscle abnormalities in rats with experimentally induced heart hypertrophy and failure. Basic research in cardiology, 2003, Volume: 98, Issue:2 Topics: Animals; Disease Models, Animal; Heart Failure; Hypertrophy, Right Ventricular; Monocrotaline; Muscle, Skeletal; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley	2003
Tachykinin dysfunction attenuates monocrotaline-induced pulmonary hypertension. Toxicology and applied pharmacology, 2003, Mar-15, Volume: 187, Issue:3 Topics: Animals; Blood Pressure; Body Weight; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Organ Size; Rats; Rats, Wistar; Receptors, Tachykinin; RNA Interference; RNA, Double-Stranded; Substance P; Tachykinins	2003
Effect of a surgical aortocaval fistula on monocrotaline-induced pulmonary hypertension. Critical care medicine, 2003, Volume: 31, Issue:4 Topics: Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Blood Pressure; Cardiac Output; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tunica Intima; Ultrasonography, Doppler; Vena Cava, Inferior	2003
Activation of the right ventricular endothelin (ET) system in the monocrotaline model of pulmonary hypertension: response to chronic ETA receptor blockade. Clinical science (London, England : 1979), 2003, Volume: 105, Issue:6 Topics: Animals; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Endothelins; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Phenylpropionates; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A	2003
Mechanical load-dependent regulation of gene expression in monocrotaline-induced right ventricular hypertrophy in the rat. Circulation research, 2003, Aug-08, Volume: 93, Issue:3 Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Biomechanical Phenomena; Body Weight; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Myocardial Contraction; Norepinephrine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stress, Mechanical	2003
Contractile reserve but not tension is reduced in monocrotaline-induced right ventricular hypertrophy. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:3 Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bicarbonates; Buffers; Coronary Circulation; HEPES; Hydrogen-Ion Concentration; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardial Contraction; Rats; Rats, Wistar	2004
Estrogen and enalapril attenuate the development of right ventricular hypertrophy induced by monocrotaline in ovariectomized rats. Journal of Korean medical science, 2003, Volume: 18, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Body Weight; Densitometry; Disease Progression; Enalapril; Endothelin-1; Estrogens; Female; Hypertrophy, Right Ventricular; Male; Microscopy, Electron; Monocrotaline; Ovariectomy; Rats; Rats, Sprague-Dawley; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sex Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling	2003
Progressive development of pulmonary hypertension leading to right ventricular hypertrophy assessed by echocardiography in rats. Experimental animals, 2003, Volume: 52, Issue:4 Topics: Animals; Disease Models, Animal; Disease Progression; Echocardiography; Echocardiography, Doppler, Pulsed; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Wistar	2003
Effect of nolomirole on monocrotaline-induced heart failure. Pharmacological research, 2004, Volume: 49, Issue:1 Topics: Administration, Oral; Adrenergic alpha-Agonists; Aldosterone; Animals; Ascitic Fluid; Atrial Natriuretic Factor; Body Weight; Disease Models, Animal; Dopamine Agonists; Drug Evaluation, Preclinical; Esters; Female; Heart Atria; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Indoles; Monocrotaline; Norepinephrine; Pleural Effusion; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes	2004
Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats. Circulation research, 2004, Feb-20, Volume: 94, Issue:3 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Intracellular Signaling Peptides and Proteins; Male; Monocrotaline; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Survival Rate; Time Factors	2004
Effect of endothelin antagonism on contractility, intracellular calcium regulation and calcium regulatory protein expression in right ventricular hypertrophy of the rat. Basic & clinical pharmacology & toxicology, 2004, Volume: 94, Issue:1 Topics: Animals; Blood Pressure; Body Weight; Calcium; Dioxoles; Endothelins; Female; Hypertrophy, Right Ventricular; Monocrotaline; Myocardial Contraction; Organ Size; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum	2004
Right ventricle-sparing heart transplantation effective against iatrogenic pulmonary hypertension. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2004, Volume: 23, Issue:2 Topics: Alkylating Agents; Animals; Dogs; Heart Transplantation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Iatrogenic Disease; Monocrotaline	2004
Downregulation of Kv4.2 and Kv4.3 channel gene expression in right ventricular hypertrophy induced by monocrotaline in rat. Acta pharmacologica Sinica, 2004, Volume: 25, Issue:2 Topics: Animals; Blood Pressure; Down-Regulation; Heart Septum; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Potassium Channels; Potassium Channels, Voltage-Gated; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Shal Potassium Channels	2004
Antiremodeling effects of iloprost and the dual-selective phosphodiesterase 3/4 inhibitor tolafentrine in chronic experimental pulmonary hypertension. Circulation research, 2004, Apr-30, Volume: 94, Issue:8 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Drug Therapy, Combination; Gelatinases; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Iloprost; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Muscle, Smooth, Vascular; Naphthyridines; Oxygen; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Gas Exchange; Pulmonary Heart Disease; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Ventricular Remodeling	2004
Roles of endothelin ETA and ETB receptors in the pathogenesis of monocrotaline-induced pulmonary hypertension. Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:2 Topics: Administration, Oral; Animals; Atrasentan; Blood Pressure; Body Mass Index; Body Weight; Cardiomegaly; Drug Administration Schedule; Drug Therapy, Combination; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Subcutaneous; Intubation, Gastrointestinal; Lung; Male; Monocrotaline; Organ Size; Pulmonary Artery; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Time Factors; Tunica Media; Ventricular Pressure	2004
Endogenous production of ghrelin and beneficial effects of its exogenous administration in monocrotaline-induced pulmonary hypertension. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6 Topics: Animals; Ghrelin; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptide Hormones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Ventricular Function, Left; Ventricular Function, Right	2004
Disruption of endothelial-cell caveolin-1alpha/raft scaffolding during development of monocrotaline-induced pulmonary hypertension. Circulation, 2004, Sep-14, Volume: 110, Issue:11 Topics: Animals; Caveolin 1; Caveolins; Disease Models, Animal; DNA-Binding Proteins; Endothelial Cells; Endothelium, Vascular; Heat-Shock Proteins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isomerases; Male; Membrane Microdomains; Mitosis; Monocrotaline; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Proliferating Cell Nuclear Antigen; Protein Disulfide-Isomerases; Protein Processing, Post-Translational; Pulmonary Artery; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Trans-Activators; von Willebrand Factor	2004
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circulation research, 2004, Oct-15, Volume: 95, Issue:8 Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Dichloroacetic Acid; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kv1.5 Potassium Channel; Mitochondria; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Specificity; Oxidative Phosphorylation; Potassium Channels, Voltage-Gated; Pulmonary Artery; Rats; Shab Potassium Channels; Vascular Resistance	2004
[Effect of chronic administration of aminoguanidine on the reactivity of pulmonary vessels in rats with monocrotaline-induced pulmonary hypertension]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2004, Volume: 90, Issue:7 Topics: Acetylcholine; Animals; Blood Pressure; Endothelium, Vascular; Guanidines; Guanylate Cyclase; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase	2004
Gene transfer of hepatocyte growth factor with prostacyclin synthase in severe pulmonary hypertension of rats. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2004, Volume: 26, Issue:6 Topics: Animals; Blood Pressure; Cytochrome P-450 Enzyme System; Genetic Therapy; Heart Ventricles; Hepatocyte Growth Factor; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Intramolecular Oxidoreductases; Monocrotaline; Organ Size; Pulmonary Artery; Rats; Rats, Wistar; Transfection	2004
Specific inhibition of p38 mitogen-activated protein kinase with FR167653 attenuates vascular proliferation in monocrotaline-induced pulmonary hypertension in rats. The Journal of thoracic and cardiovascular surgery, 2004, Volume: 128, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Monocrotaline; p38 Mitogen-Activated Protein Kinases; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction	2004
Repeated gene transfer of naked prostacyclin synthase plasmid into skeletal muscles attenuates monocrotaline-induced pulmonary hypertension and prolongs survival in rats. Human gene therapy, 2004, Volume: 15, Issue:12 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cyclic AMP; Cytochrome P-450 Enzyme System; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Intramolecular Oxidoreductases; Lung; Monocrotaline; Muscle, Skeletal; Plasmids; Prognosis; Pulmonary Artery; Rats; Survival Rate; Time Factors	2004
Pressure overload and neurohumoral activation differentially affect the myocardial proteome. Proteomics, 2005, Volume: 5, Issue:5 Topics: Amino Acid Sequence; Animals; Blood Pressure; Cell Cycle; Hypertrophy, Right Ventricular; Isoelectric Point; Male; Molecular Sequence Data; Monocrotaline; Muscle Proteins; Myocardium; Neurosecretory Systems; Proteome; Rats; Rats, Wistar	2005
Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension. Circulation, 2005, Jun-07, Volume: 111, Issue:22 Topics: Animals; Animals, Genetically Modified; Arterial Occlusive Diseases; Cell Proliferation; Disease Models, Animal; Hypertension; Hypertrophy, Right Ventricular; Monocrotaline; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Receptor, Endothelin B; Tunica Intima	2005
Estradiol metabolites attenuate monocrotaline-induced pulmonary hypertension in rats. Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4 Topics: 2-Methoxyestradiol; Animals; Blood Pressure; Body Weight; Cell Proliferation; Disease Progression; Estradiol; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Monocrotaline; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Time Factors; Tubulin Modulators	2005
Selective right, but not left, coronary endothelial dysfunction precedes development of pulmonary hypertension and right heart hypertrophy in rats. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2006
Cardiac hypertrophy induced by prostaglandin F(2alpha) may be mediated by calcineurin signal transduction pathway in rats. Sheng li xue bao : [Acta physiologica Sinica], 2005, Dec-25, Volume: 57, Issue:6 Topics: Animals; Calcineurin; Cells, Cultured; Dinoprost; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction	2005
Inotropic and lusitropic effects of ghrelin and their modulation by the endocardial endothelium, NO, prostaglandins, GHS-R1a and KCa channels. Peptides, 2006, Volume: 27, Issue:7 Topics: Animals; Apamin; Charybdotoxin; Endocardium; Ghrelin; Humans; Hypertrophy, Right Ventricular; Indomethacin; Monocrotaline; Nitric Oxide; Nitroarginine; Oligopeptides; Peptide Hormones; Peptides; Potassium Channels; Prostaglandins; Rats; Receptors, G-Protein-Coupled; Receptors, Ghrelin	2006
Genistein, a phytoestrogen, attenuates monocrotaline-induced pulmonary hypertension. Respiration; international review of thoracic diseases, 2006, Volume: 73, Issue:1 Topics: Animals; Blotting, Western; Down-Regulation; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Genistein; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Monocrotaline; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vascular Resistance	2006
Upregulation of profilin, cofilin-2 and LIMK2 in cultured pulmonary artery smooth muscle cells and in pulmonary arteries of monocrotaline-treated rats. Vascular pharmacology, 2006, Volume: 44, Issue:5 Topics: Animals; Cells, Cultured; Cofilin 2; Disease Models, Animal; Dogs; Hyperplasia; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation Mediators; Lim Kinases; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Profilins; Protein Kinases; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation	2006
Role of chymase-dependent angiotensin II formation in monocrotaline-induced pulmonary hypertensive rats. Pediatric research, 2006, Volume: 60, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Proliferation; Chymases; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Serine Endopeptidases; Tetrazoles; Tunica Media	2006
Remodeling excitation-contraction coupling of hypertrophied ventricular myocytes is dependent on T-type calcium channels expression. Biochemical and biophysical research communications, 2006, Jun-30, Volume: 345, Issue:2 Topics: Animals; Calcium Channels, T-Type; Gene Expression; Heart; Hypertrophy, Right Ventricular; Monocrotaline; Myocardial Contraction; Myocytes, Cardiac; Nifedipine; Rats; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical	2006
Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:5 Topics: Animals; Coronary Vessels; Disulfides; Dose-Response Relationship, Drug; Endothelium, Vascular; Garlic; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Plant Extracts; Rats; Rats, Sprague-Dawley; Sulfinic Acids; Time Factors; Vasodilation	2006
Characterization of right ventricular function after monocrotaline-induced pulmonary hypertension in the intact rat. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:5 Topics: Animals; Blood Pressure; Cardiac Output; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Male; Monocrotaline; Organ Size; Rats; Rats, Wistar; Stroke Volume; Time Factors; Ventricular Dysfunction, Right; Ventricular Pressure	2006
2-Methoxyestradiol mediates the protective effects of estradiol in monocrotaline-induced pulmonary hypertension. Vascular pharmacology, 2006, Volume: 45, Issue:6 Topics: 2-Methoxyestradiol; Analysis of Variance; Animals; Blood Pressure; Disease Progression; Estradiol; Female; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Ovariectomy; Pulmonary Artery; Rats; Time Factors; Ventricular Function, Left; Ventricular Function, Right	2006
The HMG-CoA reductase inhibitor, pravastatin, prevents the development of monocrotaline-induced pulmonary hypertension in the rat through reduction of endothelial cell apoptosis and overexpression of eNOS. Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 373, Issue:6 Topics: Acetylcholine; Animals; Apoptosis; Blood Pressure; Blotting, Western; Body Weight; Caspase 3; Disease Progression; Endothelial Cells; Heart Function Tests; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Nitroprusside; Poisons; Pravastatin; Pulmonary Artery; Rats; Rats, Wistar; Survival; Vasodilator Agents	2006
Short-term administration of a cell-permeable caveolin-1 peptide prevents the development of monocrotaline-induced pulmonary hypertension and right ventricular hypertrophy. Circulation, 2006, Aug-29, Volume: 114, Issue:9 Topics: Amino Acid Sequence; Animals; Biotinylation; Caveolin 1; Cell Membrane Permeability; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Molecular Sequence Data; Monocrotaline; Peptide Fragments; Rats; Rats, Sprague-Dawley	2006
Right ventricular hypertrophy causes impairment of left ventricular diastolic function in the rat. Basic research in cardiology, 2007, Volume: 102, Issue:1 Topics: Animals; Blood Pressure; Cardiac Volume; Collagen; Diastole; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure	2007
Mycophenolate mofetil attenuates pulmonary arterial hypertension in rats. Biochemical and biophysical research communications, 2006, Oct-20, Volume: 349, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Macrophages; Male; Monocrotaline; Mycophenolic Acid; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley	2006
Intratracheal mesenchymal stem cell administration attenuates monocrotaline-induced pulmonary hypertension and endothelial dysfunction. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:2 Topics: Acetylcholine; Animals; Blood Pressure; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Monocrotaline; Paracrine Communication; Phenotype; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Time Factors; Trachea; Vascular Resistance; Vasodilation; Vasodilator Agents	2007
Impaired NO-mediated vasodilation with increased superoxide but robust EDHF function in right ventricular arterial microvessels of pulmonary hypertensive rats. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:6 Topics: Acetylcholine; Animals; Biological Factors; Catalase; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microcirculation; Microscopy, Video; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tetraethylammonium; Vasodilation; Vasodilator Agents	2007
Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:6 Topics: Amidohydrolases; Animals; Arginase; Arginine; Cyclic GMP; Endothelial Cells; Enzyme Activation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isometric Contraction; Lung; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction	2007
Inhibitory effect of ginsenoside Rb1 on cardiac hypertrophy induced by monocrotaline in rat. Journal of ethnopharmacology, 2007, May-22, Volume: 111, Issue:3 Topics: Animals; Atrial Natriuretic Factor; Blotting, Western; Calcineurin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Gene Expression Regulation; Ginsenosides; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; Panax; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction	2007
Activity of endothelium-derived hyperpolarizing factor is augmented in monocrotaline-induced pulmonary hypertension of rat lungs. Journal of vascular research, 2007, Volume: 44, Issue:4 Topics: Animals; Anti-Infective Agents; Apamin; Biological Factors; Charybdotoxin; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfaphenazole; Thapsigargin; Vascular Cell Adhesion Molecule-1; Vasodilation	2007
Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy. Circulation research, 2007, Jun-22, Volume: 100, Issue:12 Topics: Adrenergic Fibers; Animals; Dopamine; Endothelin-1; GAP-43 Protein; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kinetics; Male; Monocrotaline; Myocytes, Cardiac; Nerve Growth Factor; Neural Cell Adhesion Molecule L1; Norepinephrine; Rats; Rats, Wistar; Sialic Acids; Tubulin; Tyrosine 3-Monooxygenase; Up-Regulation	2007
Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:2 Topics: Action Potentials; Animals; Body Surface Potential Mapping; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardial Contraction; Rats; Rats, Wistar; Severity of Illness Index; Systole; Time Factors; Ultrasonography; Ventricular Function, Right; Ventricular Pressure	2007
Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:3 Topics: Angiography; Animals; Cell Proliferation; Disease Models, Animal; Endothelial Cells; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Thromboplastin; Vascular Endothelial Growth Factor Receptor-2; von Willebrand Factor	2007
Preservation of diastolic function in monocrotaline-induced right ventricular hypertrophy in rats. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:3 Topics: Adenine Nucleotides; Animals; Blood Pressure; Collagen; Creatine; Dietary Supplements; Folic Acid; Heart Ventricles; Homocysteine; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardial Contraction; Random Allocation; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Function, Right	2007
Adenoassociated virus-mediated prostacyclin synthase expression prevents pulmonary arterial hypertension in rats. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Pressure; Cell Line; Cytochrome P-450 Enzyme System; Dependovirus; Epoprostenol; Feasibility Studies; Gene Transfer Techniques; Genetic Vectors; Heart Rate; Humans; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Injections, Intramuscular; Intramolecular Oxidoreductases; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Wistar; Survival Analysis	2007
Oral sildenafil prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats. Interactive cardiovascular and thoracic surgery, 2007, Volume: 6, Issue:5 Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Endothelin-1; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Lung Diseases, Interstitial; Male; Monocrotaline; Piperazines; Pulmonary Artery; Pulmonary Emphysema; Purines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sildenafil Citrate; Sulfones; Time Factors; Vasodilator Agents	2007
Effects of combined therapy with a Rho-kinase inhibitor and prostacyclin on monocrotaline-induced pulmonary hypertension in rats. Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:2 Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epoprostenol; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Protein Kinase Inhibitors; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Vasodilator Agents	2007
Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension. Pathology, research and practice, 2007, Volume: 203, Issue:12 Topics: Animals; Cardiac Output; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Signal Transduction	2007
[Effect of triptolide on the development of monocrotaline-induced pulmonary hypertension in pneumonectomized rat]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2007, Volume: 38, Issue:5 Topics: Animals; Antihypertensive Agents; Diterpenes; Epoxy Compounds; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Phenanthrenes; Pneumonectomy; Rats; Rats, Sprague-Dawley	2007
Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition. The European respiratory journal, 2008, Volume: 31, Issue:3 Topics: Animals; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Naphthyridines; Phosphodiesterase 3 Inhibitors; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Rats	2008
Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:2 Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Coronary Disease; Endothelium, Vascular; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide; Organ Size; Poisons; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Sulfonamides	2008
Evaluation of olmesartan medoxomil in the rat monocrotaline model of pulmonary hypertension. Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:1 Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Olmesartan Medoxomil; Pulmonary Artery; Rats; Rats, Wistar; Tetrazoles; Time Factors	2008
Pyrrolidine dithiocarbamate restores endothelial cell membrane integrity and attenuates monocrotaline-induced pulmonary artery hypertension. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 294, Issue:6 Topics: Acridines; Animals; Caveolin 1; Cell Membrane; Endothelial Cells; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; I-kappa B Proteins; Luminescent Measurements; Male; Monocrotaline; NF-kappa B; NF-KappaB Inhibitor alpha; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; STAT3 Transcription Factor; Superoxides; Thiocarbamates	2008
Effects of a chronic exercise training protocol on oxidative stress and right ventricular hypertrophy in monocrotaline-treated rats. Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:8 Topics: Animals; Catalase; Glutathione Transferase; Hypertrophy, Right Ventricular; Male; Monocrotaline; Oxidative Stress; Physical Conditioning, Animal; Pulmonary Heart Disease; Rats; Rats, Wistar; Superoxide Dismutase; Weight Gain	2008
Calcium transients in single myocytes and membranous ultrastructures during the development of cardiac hypertrophy and heart failure in rats. Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:12 Topics: Animals; Calcium; Cell Membrane; Heart Failure; Hypertrophy, Right Ventricular; Isometric Contraction; Isoproterenol; Male; Microscopy, Electron, Scanning; Mitochondria, Heart; Monocrotaline; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum	1994
Intraventricular changes in the beta-adrenoceptor-adenylate cyclase system of the rat heart with the progress of monocrotaline-induced right ventricular hypertrophy. Japanese circulation journal, 1994, Volume: 58, Issue:11 Topics: 5'-Nucleotidase; Adenylyl Cyclases; Animals; Cell Membrane; Heart Septum; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Sodium-Potassium-Exchanging ATPase	1994
Activation of ANP synthesis during congestive heart failure in rats treated with monocrotaline. The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2 Topics: Animals; Ascitic Fluid; Atrial Natriuretic Factor; Cardiomegaly; Female; Gene Expression; Heart Failure; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Organ Specificity; Pleural Effusion; Rats; Rats, Sprague-Dawley; RNA, Messenger	1995
Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline. American journal of respiratory cell and molecular biology, 1994, Volume: 11, Issue:6 Topics: Animals; Blood Pressure; Disease Models, Animal; Gene Expression Regulation; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Interleukin; Recombinant Proteins; RNA, Messenger; Sialoglycoproteins	1994
Contrasting effects of an angiotensin converting enzyme inhibitor and a calcium antagonist on calcium transients in isolated rat cardiac myocytes. Cardiovascular research, 1994, Volume: 28, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Hypertrophy, Right Ventricular; Indans; Male; Monocrotaline; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta	1994
Interleukin-1 receptor antagonist inhibits pulmonary hypertension induced by inflammation. Annals of the New York Academy of Sciences, 1994, May-28, Volume: 725 Topics: Animals; Blood Pressure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Lung; Male; Monocrotaline; Organ Size; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; RNA, Messenger; Sialoglycoproteins	1994
Cardiovascular responses to hemorrhage during acute and chronic hypoxia. The American journal of physiology, 1994, Volume: 267, Issue:3 Pt 2 Topics: Acute Disease; Animals; Blood Volume; Cardiovascular System; Chronic Disease; Gases; Hematocrit; Hemodynamics; Hemorrhage; Hypertrophy, Right Ventricular; Hypoxia; Male; Monocrotaline; Rats; Rats, Sprague-Dawley	1994
Alterations of growth factor transcripts in rat lungs during development of monocrotaline-induced pulmonary hypertension. Biochemical pharmacology, 1993, Sep-14, Volume: 46, Issue:6 Topics: Animals; Gene Expression; Growth Substances; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors	1993
Protection by oestradiol against the development of cardiovascular changes associated with monocrotaline pulmonary hypertension in rats. British journal of pharmacology, 1993, Volume: 110, Issue:2 Topics: Animals; Behavior, Animal; Body Weight; Drug Implants; Estradiol; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Organ Size; Pulmonary Artery; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Sprague-Dawley	1993
Cardiac atrial natriuretic peptide in monocrotaline-induced pulmonary hypertensive rats. Acta paediatrica Japonica : Overseas edition, 1993, Volume: 35, Issue:4 Topics: Animals; Atrial Natriuretic Factor; Disease Models, Animal; Heart Atria; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Time Factors	1993
Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension. Circulation research, 1993, Volume: 73, Issue:5 Topics: Animals; Endothelin-1; Endothelins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Lung; Male; Monocrotaline; Peptides, Cyclic; Protein Precursors; Pulmonary Artery; Rats; Rats, Wistar; RNA, Messenger; Vasoconstriction	1993
Strain differences in the response of Fischer 344 and Sprague-Dawley rats to monocrotaline induced pulmonary vascular disease. Toxicology, 1993, Mar-30, Volume: 79, Issue:1 Topics: Animals; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Species Specificity; Weight Gain	1993
Role of nitric oxide and endothelin-1 in monocrotaline-induced pulmonary hypertension in rats. Cardiovascular research, 1995, Volume: 30, Issue:5 Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Calcimycin; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Indomethacin; Male; Monocrotaline; Nitric Oxide; Nitroglycerin; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation	1995
Right heart failure chronically stimulates heat shock protein 72 in heart and liver but not in other tissues. Cardiovascular research, 1996, Volume: 31, Issue:6 Topics: Animals; Autoradiography; Blotting, Western; Female; Heart Failure; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Hypertrophy, Right Ventricular; Liver; Lung; Monocrotaline; Muscle, Skeletal; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley	1996
[Role of peptide leukotrienes in monocrotaline-induced lung disease]. Nihon Kyobu Shikkan Gakkai zasshi, 1995, Volume: 33, Issue:12 Topics: Animals; Chromones; Hypertrophy, Right Ventricular; Leukotriene C4; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley	1995
Induction of right ventricular hypertrophy in neonatal guinea pigs by monocrotaline. Japanese circulation journal, 1996, Volume: 60, Issue:8 Topics: Animals; Disease Models, Animal; Guinea Pigs; Humans; Hypertrophy, Right Ventricular; Monocrotaline; Poisons	1996
Role of inhibition of nitric oxide production in monocrotaline-induced pulmonary hypertension. Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 82, Issue:5 Topics: Animals; Arterioles; Blood Pressure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Subcutaneous; Male; Molsidomine; Monocrotaline; Nitrates; Nitric Oxide; Poisons; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Weight Gain	1997
Stage-dependent changes in membrane currents in rats with monocrotaline-induced right ventricular hypertrophy. The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2 Topics: Action Potentials; Animals; Electric Conductivity; Hypertrophy, Right Ventricular; Male; Membranes; Monocrotaline; Myocardium; Patch-Clamp Techniques; Rats; Rats, Wistar; Reference Values; Ventricular Function	1997
The orally active ET(A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphe nyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-treated ra The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:3 Topics: Administration, Oral; Animals; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Peptidyl-Dipeptidase A; Phenylpropionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Ventricular Function, Right	1997
Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension. The American journal of pathology, 1997, Volume: 151, Issue:4 Topics: Actins; Animals; Disease Models, Animal; Hemodynamics; Hyperplasia; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Monocrotaline; Pneumonectomy; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms; Tunica Intima	1997
Nonspecific endothelin-receptor antagonist blunts monocrotaline-induced pulmonary hypertension in rats. Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:4 Topics: Animals; Antihypertensive Agents; Bosentan; Cardiac Output; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Neovascularization, Pathologic; Organ Size; Poisons; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Sulfonamides	1997
Cardiac and vascular responses after monocrotaline-induced hypertrophy in rats. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1 Topics: Animals; Body Weight; Disease Models, Animal; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardial Contraction; Poisons; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stimulation, Chemical; Vasoconstriction	1998
Endothelin converting enzyme inhibitor protects development of right ventricular overload and medial thickening of pulmonary arteries in rats with monocrotaline-induced pulmonary hypertension. Life sciences, 1998, Volume: 63, Issue:10 Topics: Animals; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin-Converting Enzymes; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy; Hypertrophy, Right Ventricular; Male; Metalloendopeptidases; Monocrotaline; Organ Size; Poisons; Pulmonary Artery; Rats; Rats, Wistar; Tetracyclines	1998
Chronic infusion of adrenomedullin reduces pulmonary hypertension and lessens right ventricular hypertrophy in rats administered monocrotaline. European journal of pharmacology, 1998, Aug-14, Volume: 355, Issue:1 Topics: Adrenomedullin; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infusion Pumps, Implantable; Lung; Male; Monocrotaline; Organ Size; Peptides; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar	1998
[Preventive effects of tetrandrine on pulmonary hypertension and right ventricular hypertrophy in rats induced by monocrotaline]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1996, Volume: 21, Issue:12 Topics: Alkaloids; Animals; Benzylisoquinolines; Blood Pressure; Calcium Channel Blockers; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Rats; Rats, Wistar	1996
Variable expression of endothelial NO synthase in three forms of rat pulmonary hypertension. The American journal of physiology, 1999, Volume: 276, Issue:2 Topics: Animals; Enzyme Inhibitors; Guanidines; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Male; Monocrotaline; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroarginine; Pulmonary Circulation; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; RNA, Messenger; Tissue Distribution; Vasomotor System	1999
Endothelin-1 is elevated in monocrotaline pulmonary hypertension. The American journal of physiology, 1999, Volume: 276, Issue:2 Topics: Angiotensin II; Animals; Drug Combinations; Endothelin-1; Endothelins; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Lung; Male; Monocrotaline; Oligopeptides; omega-N-Methylarginine; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Vasoconstriction	1999
Tetrandrine inhibited chronic "inflammatory" pulmonary hypertension in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:5 Topics: Alkaloids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Rats; Rats, Wistar	1997
Dietary retinol inhibits inflammatory responses of rats treated with monocrotaline. The Journal of nutrition, 1999, Volume: 129, Issue:7 Topics: Animals; Carcinogens; Diet; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammation; Injections, Subcutaneous; Lung; Male; Monocrotaline; Pulmonary Artery; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Vitamin A	1999
Impaired endothelium-dependent relaxation by adrenomedullin in monocrotaline-treated rat arteries. European journal of pharmacology, 1999, Sep-03, Volume: 380, Issue:1 Topics: Acetylcholine; Adrenomedullin; Animals; Aorta, Thoracic; Body Weight; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Organ Size; Peptides; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Vasodilation; Vasodilator Agents	1999
Dietary beta-carotene protects lung and liver parenchyma of rats treated with monocrotaline. Toxicology, 1999, Sep-20, Volume: 137, Issue:2 Topics: Animals; Antidotes; Antioxidants; beta Carotene; Chemical and Drug Induced Liver Injury; Collagen; Diet; Fatty Liver; Hemorrhage; Hypertrophy, Right Ventricular; Liver; Lung; Lung Diseases; Male; Monocrotaline; Poisons; Rats; Rats, Sprague-Dawley	1999
Apoptosis and atrophy in rat slow skeletal muscles in chronic heart failure. The American journal of physiology, 1999, Volume: 277, Issue:5 Topics: Animals; Apoptosis; Atrophy; Blotting, Western; Body Weight; Caspase 3; Caspases; Cell Nucleus; Chronic Disease; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Male; Monocrotaline; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Ubiquitins	1999
(+)-[3H]isradipine and [3H]glyburide bindings to heart and lung membranes from rats with monocrotaline-induced pulmonary hypertension. Japanese journal of pharmacology, 1999, Volume: 81, Issue:2 Topics: Animals; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Calcium Channels, L-Type; Glyburide; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoglycemic Agents; In Vitro Techniques; Isradipine; KATP Channels; Kinetics; Lung; Male; Membranes; Monocrotaline; Myocardium; Poisons; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley	1999
Cardiac endothelin and big endothelin in right-heart hypertrophy due to monocrotaline-induced pulmonary hypertension in rat. Cardiovascular research, 1999, Volume: 44, Issue:1 Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelin-1; Endothelins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Perfusion; Poisons; Protein Precursors; Rats; Rats, Sprague-Dawley	1999
Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension. Circulation research, 2000, Apr-28, Volume: 86, Issue:8 Topics: Animals; Cell Communication; Gap Junctions; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Male; Monocrotaline; Rats; Rats, Wistar	2000
Effects of concentrated ambient particles in rats and hamsters: an exploratory study. Research report (Health Effects Institute), 2000, Issue:93 Topics: Age Factors; Air Pollutants; Air Pollution; Animals; Blood Cell Count; Cardiomyopathies; Cricetinae; Disease Models, Animal; Heart Rate; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Maximum Allowable Concentration; Mesocricetus; Monocrotaline; Mortality; Particle Size; Rats; Rats, Inbred F344; Time Factors	2000
Calcium handling and role of endothelin-1 in monocrotaline right ventricular hypertrophy of the rat. Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:11 Topics: Animals; Calcium; Calcium Signaling; Diastole; Endothelin-1; Hypertrophy, Right Ventricular; Ion Transport; Monocrotaline; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Systole; Ventricular Function, Right	2000
Enhanced expression and activity of xanthine oxidoreductase in the failing heart. Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:11 Topics: Animals; Coronary Vessels; Disease Models, Animal; Disease Progression; Enzyme Induction; Female; Free Radicals; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Ligation; Monocrotaline; Muscle Proteins; Myocardial Infarction; Organ Size; Rats; Rats, Sprague-Dawley; Xanthine Oxidase	2000
Chronic treatment with probucol effectively inhibits progression of pulmonary hypertension in rats. Life sciences, 2000, Sep-08, Volume: 67, Issue:16 Topics: Animals; Anticholesteremic Agents; Blood Pressure; Diet; Disease Progression; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Probucol; Rats; Rats, Wistar; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure	2000
Endothelin-A-receptor antagonist and oral prostacyclin analog are comparably effective in ameliorating pulmonary hypertension and right ventricular hypertrophy in rats. Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1 Topics: Administration, Oral; Animals; Endothelin Receptor Antagonists; Epoprostenol; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Sulfonamides	2000
Capsaicin pre- and post-treatment on rat monocrotaline pneumotoxicity. The Chinese journal of physiology, 2000, Dec-31, Volume: 43, Issue:4 Topics: Animals; Capsaicin; Functional Residual Capacity; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Neprilysin; Neurokinin A; Organ Size; Rats; Rats, Sprague-Dawley; Substance P; Total Lung Capacity	2000
Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure. Circulation, 2001, May-01, Volume: 103, Issue:17 Topics: Angiotensin II; Animals; Apoptosis; Biphenyl Compounds; Calcium Channel Blockers; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infusion Pumps, Implantable; Irbesartan; Male; Monocrotaline; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Nifedipine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha	2001
Enhanced gene expression of renin-angiotensin system, TGF-beta1, endothelin-1 and nitric oxide synthase in right-ventricular hypertrophy. Pharmacological research, 2001, Volume: 43, Issue:3 Topics: Animals; Disease Models, Animal; Endothelin-1; Gene Expression; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Transforming Growth Factor beta; Transforming Growth Factor beta1	2001
Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Cell Size; Enzyme Inhibitors; Guanidines; Heart Failure; Hemodynamics; Hypertrophy, Right Ventricular; Lung; Lung Diseases; Male; Monocrotaline; Myocardium; Organ Size; Poisons; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sulfones	2001
Angiotensin-converting enzyme inhibitor preserves p21 and endothelial nitric oxide synthase expression in monocrotaline-induced pulmonary arterial hypertension in rats. Circulation, 2001, Aug-21, Volume: 104, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dietary Fats; Disease Models, Animal; Enalapril; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Lung; Magnetic Resonance Imaging; Male; Monocrotaline; Nitrates; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Perfusion; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction	2001
Time- and subunit-dependent differential mRNA expression of L-type Ca2+ channel during progression of right ventricular hypertrophy. Japanese heart journal, 2001, Volume: 42, Issue:5 Topics: Animals; Blotting, Northern; Calcium Channels, L-Type; Hypertrophy, Right Ventricular; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors	2001
Defective intracellular calcium handling in monocrotaline-induced right ventricular hypertrophy: protective effect of long-term endothelin-A receptor blockade with 2-benzo[1,3]dioxol-5-yl-3-benzyl-4-(4-methoxy-phenyl-)- 4-oxobut-2-enoate-sodium (PD 155080 The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:2 Topics: Aequorin; Animals; Calcium; Calcium Signaling; Dioxoles; Endothelin Receptor Antagonists; Endothelin-1; Female; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Luminescent Measurements; Monocrotaline; Myocardial Contraction; Perfusion; Poisons; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Ventricular Function, Right	2002
Changes in alpha(1)-adrenergic vascular reactivity in monocrotaline-treated rats. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:2 Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Mesenteric Arteries; Monocrotaline; Norepinephrine; Piperazines; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Thoracic Arteries; Vasoconstriction	2002
The effects of vasoactive intestinal peptide on monocrotaline induced pulmonary hypertensive rabbits following cardiopulmonary bypass: a comparative study with isoproteronol and nitroglycerine. Cardiovascular surgery (London, England), 2002, Volume: 10, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Cardiopulmonary Bypass; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isoproterenol; Male; Monocrotaline; Nitroglycerin; Propranolol; Rabbits; Vasoactive Intestinal Peptide; Vasodilator Agents; Verapamil	2002
Attenuation of negatively regulated ANP secretion by calcium in hypertrophied atria. Regulatory peptides, 2002, May-30, Volume: 105, Issue:3 Topics: Animals; Atrial Natriuretic Factor; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; Feedback, Physiological; Heart Atria; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Myocardial Contraction; Myocardium; Radioimmunoassay; Rats; Rats, Sprague-Dawley	2002
Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats. Toxicology, 2002, Jun-14, Volume: 175, Issue:1-3 Topics: Animals; Chemical and Drug Induced Liver Injury; Dietary Fats; Fatty Acids, Unsaturated; Fish Oils; Histocytochemistry; Hypertrophy, Right Ventricular; Liver; Liver Cirrhosis; Lung; Male; Monocrotaline; Pneumonia; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Sprague-Dawley	2002
Monocrotaline-induced structural remodeling of the intra-acinar pulmonary arteries and pulmonary hypertension. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1992, Volume: 12, Issue:4 Topics: Animals; Arterioles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Wistar	1992