monocrotaline has been researched along with Cirrhosis in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 21 (58.33) | 24.3611 |
| 2020's | 11 (30.56) | 2.80 |
| Authors | Studies |
|---|---|
| Dohi, K; Hirayama, M; Ito, H; Kabwe, JC; Ko, H; Maruyama, J; Maruyama, K; Mashimo, T; Mitani, Y; Miyasaka, Y; Nishimura, Y; Ohashi, H; Okamoto, R; Oshita, H; Otsuki, S; Oya, K; Sawada, H; Tsuboya, N; Yodoya, N; Zhang, E | 1 |
| Al-Qazazi, R; Archer, SL; Bentley, RET; Bonnet, S; Chen, KH; Dasgupta, A; Jones, O; Lima, PDA; Martin, AY; Maurice, DH; Mewburn, J; Potus, F; Prins, KW; Prisco, SZ; Provencher, S; Tian, L; Wu, D | 1 |
| Baranowska-Kuczko, M; Kasacka, I; Kozłowska, H; Krzyżewska, A | 1 |
| Bo, Y; Cui, Z; Tianxin, Y; Weiguo, W; Yi, Y; Zhangchi, L | 1 |
| Al-Omran, M; Bhatt, DL; Chowdhury, B; Connelly, KA; Hess, DA; Kabir, MG; Luu, AZ; Luu, VZ; Mazer, CD; Pan, Y; Quan, A; Sabongui, S; Teoh, H; Verma, S | 1 |
| Chen, H; Gao, X; He, K; Li, C; Li, H; Li, X; Liu, C; Wei, Q; Zhang, Z | 1 |
| Archer, SL; Bonnet, S; Chen, KH; Dasgupta, A; Hindmarch, CCT; Hong, Z; Kutty, S; Lima, PDA; Mewburn, J; Potus, F; Provencher, S; Sutendra, G; Tian, L; Wu, D; Zhao, YY | 1 |
| Cheng, Y; Huang, C; Li, H; Li, J; Luo, J; Rao, P; Wang, L; Wang, X | 1 |
| Kaisho, M; Okada, M; Otani, K; Sugiyama, A; Yamawaki, H | 1 |
| Akagi, S; Amioka, N; Ito, H; Kobayashi, K; Kondo, M; Miyoshi, T; Nakamura, K; Nakayama, R; Ohno, Y; Takaya, Y; Yoshida, M | 1 |
| Askaripour, M; Beik, A; Jafari, E; Jafarinejad-Farsangi, S; Joukar, S; Najafipour, H; Rajabi, S; Safi, Z | 1 |
| He, J; Li, T; Li, X; Liu, Y; Luo, H; Qi, Q; Yu, Z; Zhao, L | 1 |
| Chen, W; Dong, J; Gao, D; Guo, H; Lu, Y; Pan, X; Sun, Y; Xu, D; Xu, Y | 1 |
| Kakuda, C; Kameshima, S; Kodama, T; Okada, M; Okamura, Y; Sakamoto, Y; Yamawaki, H | 1 |
| Chen, IC; Huang, CC; Lai, YJ; Li, HH | 1 |
| Cheng, Y; Han, H; He, M; Kong, H; Li, X; Wang, H; Wang, J; Wei, G; Xie, W; Xu, J; Zhu, J; Zuo, X | 1 |
| Ding, XY; Guo, DC; Li, C; Li, YD; Lu, XZ; Shi, YP; Wang, YD; Wu, XP | 1 |
| Huang, Y; Jing, ZC; Li, J; Liu, YW; Meng, J; Pan, HZ; Wang, PH; Xiang, L; Yang, J; Zhang, H; Zhang, XL | 1 |
| Adams, V; Boekschoten, MV; Bowen, TS; van Norren, K; Vinke, P; Witkamp, RF | 1 |
| Barros, SS; Borges, AS; Colegate, SM; Maia, LA; Medeiros, RM; Pessoa, AF; Pessoa, CR; Riet-Correa, F; Soares, MP | 1 |
| Fernandez, R; Guo, Q; Huang, JA; Yamamura, A; Yamamura, H; Yuan, JX; Zimnicka, AM | 1 |
| Alemanni, M; Altomare, C; Barile, L; Cornaghi, L; Gobbi, M; Latini, R; Lucchetti, J; Mostacciuolo, G; Rizzetto, R; Rocchetti, M; Ronchi, C; Russo, I; Sala, L; Staszewsky, LI; Zambelli, V; Zaza, A | 1 |
| Bruce, E; Espejo, A; Francis, J; Horowitz, A; Katovich, MJ; Nair, A; Oswalt, A; Raizada, MK; Rathinasabapathy, A; Shenoy, V; Steckelings, UM; Sumners, C; Unger, T | 1 |
| Baldus, S; Behringer, A; Berghausen, EM; Blaschke, F; Caglayan, E; Er, F; Gassanov, N; Kappert, K; Odenthal, M; Rosenkranz, S; Ten Freyhaus, H; Trappiel, M; Wellnhofer, E | 1 |
| Bauer, R; Berndt, A; Betge, S; Franz, M; Grün, K; Jung, C; Lichtenauer, M; Ndongson-Dongmo, B; Neri, D; Petersen, I; Rohm, I; Schulze, PC | 1 |
| Chen, M; Guan, X; Li, Y; Wang, X; Wang, Y; Zhang, J; Zhang, L | 1 |
| Geng, J; Jiang, Z; Liu, Q; Lu, D; Shan, Q; Song, J; Wang, K; Zhang, B | 1 |
| Hara, Y; Harada, T; Hori, Y; Kikuzuki, R; Okada, M; Yamawaki, H | 1 |
| Ellinghaus, P; Janssen, W; Kast, R; Klein, M; Kramer, F; Lustig, K; Milting, H; Schäfer, S | 1 |
| Hara, Y; Harada, T; Kikuzuki, R; Okada, M; Yamawaki, H | 1 |
| Beliën, JA; Grunberg, K; Hadi, AM; Meijer, GA; Mouchaers, KT; Schalij, I; van der Laarse, WJ; Vonk-Noordegraaf, A | 2 |
| Brandes, RP; Cornitescu, T; Dahal, BK; Davie, N; Ghofrani, HA; Grimminger, F; Janssen, W; Kojonazarov, B; Kosanovic, D; Luitel, H; Schermuly, RT; Seeger, W; Sydykov, A; Weissmann, N | 1 |
| Eghbali, M; Li, J; Maltese, F; Nadadur, RD; Partownavid, P; Umar, S; van der Laarse, A | 1 |
| Bogaards, SJ; de Man, FS; Handoko, ML; Paulus, WJ; Postmus, PE; Schalij, I; van Ballegoij, JJ; van der Velden, J; Vonk-Noordegraaf, A; Westerhof, N | 1 |
| Bessho, K; Fukushima, N; Ichikawa, H; Matsuda, H; Mizuno, S; Nakamura, T; Ono, M; Sawa, Y | 1 |
36 other study(ies) available for monocrotaline and Cirrhosis
| Article | Year |
|---|---|
CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension.
Topics: Animals; Bone Morphogenetic Protein Receptors, Type II; Clustered Regularly Interspaced Short Palindromic Repeats; Fibrosis; Humans; Hypertension, Pulmonary; Lung; Mice; Monocrotaline; Point Mutation; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Tadalafil | 2022 |
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
Topics: Animals; Atrial Natriuretic Factor; Cytokine Receptor gp130; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fibrosis; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammasomes; Macrophage Activation; Macrophages; Monocrotaline; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Arterial Hypertension; Rats; Ventricular Dysfunction, Right | 2022 |
Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway in monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Cannabidiol; Fibronectins; Fibrosis; Heart Failure; Hypertension, Pulmonary; Monocrotaline; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2023 |
Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.
Topics: Animals; Atrial Fibrillation; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fibrosis; Monocrotaline; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2023 |
The SGLT2 inhibitor empagliflozin reduces mortality and prevents progression in experimental pulmonary hypertension.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Fibrosis; Glucosides; Heart Ventricles; Hemodynamics; Humans; Hypertrophy, Right Ventricular; Lung; Male; Models, Animal; Monocrotaline; Mortality; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; Risk Assessment; Sodium-Glucose Transporter 2 Inhibitors; Vascular Remodeling | 2020 |
Ursolic Acid Improves Monocrotaline-Induced Right Ventricular Remodeling by Regulating Metabolism.
Topics: Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Fatty Acids; Fibrosis; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; PPAR alpha; Pulmonary Arterial Hypertension; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid; Ventricular Function, Right; Ventricular Remodeling | 2020 |
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Topics: Animals; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; Epigenesis, Genetic; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Mitochondria, Heart; Mitochondrial Dynamics; Monocrotaline; Myofibroblasts; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2020 |
Optical capture and defibrillation in rats with monocrotaline-induced myocardial fibrosis 1 year after a single intravenous injection of adeno-associated virus channelrhodopsin-2.
Topics: Animals; Animals, Newborn; Arrhythmias, Cardiac; Cardiomyopathies; Channelrhodopsins; Dependovirus; Disease Models, Animal; Female; Fibrosis; Genetic Therapy; Heart Rate; Injections, Intravenous; Male; Monocrotaline; Myocardium; Optogenetics; Rats | 2021 |
Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling.
Topics: Animals; Body Weight; Cardiotonic Agents; Collagen Type IV; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kidney; Lung; Male; Monocrotaline; Organ Size; Peptide Fragments; Rats; Rats, Wistar; Recombinant Proteins; Ventricular Remodeling | 2020 |
Efficacy of shear wave elastography for evaluating right ventricular myocardial fibrosis in monocrotaline-induced pulmonary hypertension rats.
Topics: Animals; Elasticity Imaging Techniques; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Monocrotaline; Myocardium; Rats | 2021 |
Quercetin, Perillyl Alcohol, and Berberine Ameliorate Right Ventricular Disorders in Experimental Pulmonary Arterial Hypertension: Effects on miR-204, miR-27a, Fibrotic, Apoptotic, and Inflammatory Factors.
Topics: Animals; Antioxidants; Apoptosis; Berberine; Disease Models, Animal; Fibrosis; Hypertrophy, Right Ventricular; Male; MicroRNAs; Monocrotaline; Monoterpenes; Pulmonary Arterial Hypertension; Quercetin; Rats; Rats, Wistar; Ventricular Function, Right | 2021 |
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
Topics: Adult; Animals; Biomarkers; Collagen Type III; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Galectin 3; Gene Knockdown Techniques; Heart Ventricles; Humans; Hypertension, Pulmonary; Male; Middle Aged; Monocrotaline; Myocardium; Myofibroblasts; NADPH Oxidase 4; Oxidative Stress; Primary Cell Culture; Rats; Transforming Growth Factor beta1; Up-Regulation; Ventricular Remodeling; Young Adult | 2017 |
Valsartan attenuates pulmonary hypertension via suppression of mitogen activated protein kinase signaling and matrix metalloproteinase expression in rodents.
Topics: Animals; Blood Pressure; Cell Proliferation; Extracellular Matrix; Fibrosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; MAP Kinase Signaling System; Matrix Metalloproteinases; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Monocrotaline; Phosphorylation; Rats, Sprague-Dawley; Systole; Transforming Growth Factor beta1; Valsartan; Vascular Remodeling | 2017 |
Visceral adipose tissue-derived serine protease inhibitor prevents the development of monocrotaline-induced pulmonary arterial hypertension in rats.
Topics: Animals; Apoptosis; Disease Models, Animal; Fibrosis; Hypertension, Pulmonary; Intra-Abdominal Fat; Lung; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; Serine Proteinase Inhibitors; Signal Transduction | 2017 |
EP4 Agonist L-902,688 Suppresses EndMT and Attenuates Right Ventricular Cardiac Fibrosis in Experimental Pulmonary Arterial Hypertension.
Topics: Animals; Epithelial-Mesenchymal Transition; Fibrosis; Heart Ventricles; Human Umbilical Vein Endothelial Cells; Humans; Hypertension, Pulmonary; Male; Monocrotaline; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Prostaglandin E, EP4 Subtype; Tetrazoles; Transforming Growth Factor beta | 2018 |
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Topics: Animals; Dipeptidyl-Peptidase IV Inhibitors; Fibrosis; Glomerular Mesangium; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Microcirculation; Monocrotaline; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Sitagliptin Phosphate | 2018 |
17β-estradiol preserves right ventricular function in rats with pulmonary arterial hypertension: an echocardiographic and histochemical study.
Topics: Animals; Biomarkers; Disease Models, Animal; Echocardiography; Estradiol; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Natriuretic Peptide, Brain; Rats, Sprague-Dawley; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2019 |
Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension.
Topics: Adolescent; Aldosterone; Animals; Child, Preschool; Cytokines; Disease Progression; Female; Fibrosis; Gene Expression Regulation; Humans; Hypertrophy; Lung; Male; Middle Aged; Monocrotaline; Neurotransmitter Agents; Oxidative Stress; Pulmonary Arterial Hypertension; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter; Renin-Angiotensin System; Sympathectomy; Sympathetic Nervous System | 2019 |
Anti-inflammatory nutrition with high protein attenuates cardiac and skeletal muscle alterations in a pulmonary arterial hypertension model.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Female; Fibrosis; Heart; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Mice; Mice, Inbred C57BL; Monocrotaline; Muscle, Skeletal; Pulmonary Arterial Hypertension; Pulmonary Artery; Vascular Remodeling; Ventricular Function, Right | 2019 |
Pulmonary and hepatic lesions caused by the dehydropyrrolizidine alkaloid-producing plants Crotalaria juncea and Crotalaria retusa in donkeys.
Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Crotalaria; Equidae; Fibrosis; Liver; Lung; Lung Diseases; Monocrotaline; Plant Poisoning; Pyrrolizidine Alkaloids; Seeds | 2013 |
Inhibition of the Ca(2+)-sensing receptor rescues pulmonary hypertension in rats and mice.
Topics: Animals; Blotting, Western; Calcium; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Mice; Mice, Inbred C57BL; Monocrotaline; Myocardium; Poisons; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Calcium-Sensing | 2014 |
Ranolazine prevents INaL enhancement and blunts myocardial remodelling in a model of pulmonary hypertension.
Topics: Acetanilides; Animals; Calcium Signaling; Collagen; Disease Models, Animal; Fibrosis; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Membrane Potentials; Monocrotaline; Myocytes, Cardiac; Myosin Heavy Chains; Piperazines; Pulmonary Artery; Ranolazine; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Sodium Channels; Time Factors; Vascular Remodeling; Vascular Resistance; Ventricular Function, Right; Ventricular Remodeling | 2014 |
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2015 |
Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension.
Topics: Animals; Arterial Pressure; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Macrophages, Alveolar; Male; Monocrotaline; Myocytes, Cardiac; Natriuretic Peptide, Brain; Osteopontin; Pioglitazone; PPAR gamma; Pulmonary Artery; Rats, Sprague-Dawley; Thiazolidinediones; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling | 2016 |
Lung tissue remodelling in MCT-induced pulmonary hypertension: a proposal for a novel scoring system and changes in extracellular matrix and fibrosis associated gene expression.
Topics: Actins; Animals; Disease Models, Animal; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Hemodynamics; Hypertension, Pulmonary; Lung; Monocrotaline; Oligonucleotide Array Sequence Analysis; Rats, Sprague-Dawley; Severity of Illness Index; Tenascin; Vascular Remodeling | 2016 |
Galectin-3 contributes to vascular fibrosis in monocrotaline-induced pulmonary arterial hypertension rat model.
Topics: Animals; Disease Models, Animal; Fibrosis; Galectin 3; Hypertension, Pulmonary; Male; Matrix Metalloproteinase 9; Monocrotaline; Rats; Rats, Wistar; STAT3 Transcription Factor; Transforming Growth Factor beta1; Vascular Diseases | 2017 |
Effects of renal denervation on monocrotaline induced pulmonary remodeling.
Topics: Airway Remodeling; Animals; Blood Vessels; Denervation; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Kaplan-Meier Estimate; Kidney; Lung; Male; Monocrotaline; Rats; Renin-Angiotensin System | 2017 |
Captopril attenuates matrix metalloproteinase-2 and -9 in monocrotaline-induced right ventricular hypertrophy in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Captopril; Disease Models, Animal; Echocardiography; Fibrosis; Gene Expression Regulation; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocytes, Cardiac; Rats; Rats, Wistar; Ventricular Dysfunction, Right | 2008 |
Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling.
Topics: Administration, Oral; Animals; Blood Pressure; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Fibrillar Collagens; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Natriuretic Peptides; Osteopontin; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Rats, Wistar; RNA, Messenger; Sildenafil Citrate; Stroke Volume; Sulfones; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Ventricular Pressure; Ventricular Remodeling | 2009 |
Effects of telmisartan on right ventricular remodeling induced by monocrotaline in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Body Weight; Echocardiography; Fibrosis; Histocytochemistry; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Organ Size; Rats; Rats, Wistar; Stroke Volume; Systole; Telmisartan; Transforming Growth Factor beta1; Ventricular Remodeling | 2009 |
Rapid quantification of myocardial fibrosis: A new macro-based automated analysis.
Topics: Aged; Animals; Automation, Laboratory; Azo Compounds; Cardiomyopathies; Coloring Agents; Disease Models, Animal; Fibrosis; Humans; Hypertension, Pulmonary; Image Interpretation, Computer-Assisted; Male; Microscopy, Polarization; Monocrotaline; Myocardium; Rats; Rats, Wistar | 2010 |
Rapid quantification of myocardial fibrosis: a new macro-based automated analysis.
Topics: Animals; Automation; Azo Compounds; Body Weight; Electrocardiography; Fibrosis; Hemodynamics; Humans; Hypertension, Pulmonary; Image Processing, Computer-Assisted; Microscopy, Polarization; Monocrotaline; Myocardium; Organ Size; Paraffin Embedding; Rats; Rats, Wistar; Time Factors; Ultrasonography | 2011 |
Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Disease Models, Animal; Echocardiography, Doppler; Endothelin A Receptor Antagonists; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isoxazoles; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sulfones; Time Factors; Ventricular Function, Right; Ventricular Remodeling | 2011 |
Intralipid prevents and rescues fatal pulmonary arterial hypertension and right ventricular failure in rats.
Topics: Actins; Animals; Apoptosis; Blotting, Western; Caspase 3; Emulsions; Fat Emulsions, Intravenous; Fibrosis; Heart; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Microscopy, Confocal; Monocrotaline; Myocardium; Phospholipids; Platelet Endothelial Cell Adhesion Molecule-1; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Soybean Oil; Vascular Endothelial Growth Factor A | 2011 |
Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Antihypertensive Agents; Bisoprolol; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Echocardiography; Fibrosis; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Male; Monocrotaline; Rats; Rats, Wistar; Signal Transduction; Vascular Resistance | 2012 |
Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats.
Topics: Animals; Arterioles; Collagen; Endothelin-1; Extracellular Matrix; Fibrosis; Genetic Therapy; Hepatocyte Growth Factor; Humans; Hyperplasia; Hypertension, Pulmonary; Male; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Proto-Oncogene Proteins c-met; Rats; Rats, Wistar; Transfection; Transforming Growth Factor beta; Tunica Media | 2004 |