monocrotaline and Chronic Disease

Topics: Animals; Animals, Newborn; Chronic Disease; Disease Models, Animal; Humans; Hypertension, Pulmonary; Monocrotaline; Rats

Topics: Animals; Chronic Disease; Disease Models, Animal; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Rats; Rats, Wistar; Ventricular Remodeling

Topics: Animals; Arterial Pressure; Chronic Disease; Disease Models, Animal; Humans; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Pulmonary Artery; Rats; Rats, Wistar; Severity of Illness Index; Vascular Resistance

Topics: Animals; Benzamides; Bone Morphogenetic Protein Receptors, Type II; Bone Morphogenetic Proteins; Cell Movement; Chronic Disease; Disease Models, Animal; Disease Progression; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Muscle, Smooth, Vascular; Protein Serine-Threonine Kinases; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta

Topics: Animals; Chronic Disease; Hypertension, Pulmonary; Hypoxia; Least-Squares Analysis; Lung; Monocrotaline; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Spectroscopy, Near-Infrared

Topics: Animals; Cardiac Pacing, Artificial; Chronic Disease; Disease Models, Animal; Heart Failure; Heart Septum; Hypertension, Pulmonary; In Vitro Techniques; Magnetic Resonance Imaging; Male; Monocrotaline; Myocardial Contraction; Perfusion; Rats; Reproducibility of Results; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure

Topics: Administration, Inhalation; Animals; Cell Division; Cells, Cultured; Chronic Disease; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocrotaline; Myocytes, Smooth Muscle; Nitric Oxide; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sodium Nitrite; Xanthine Dehydrogenase

Topics: Animals; Cell Hypoxia; Cells, Cultured; Chronic Disease; Disease Models, Animal; Endothelial Cells; Fibroblasts; Gene Expression Profiling; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; MicroRNAs; Monocrotaline; Muscle, Smooth, Vascular; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Ribonuclease III; Time Factors

Topics: Animals; Blotting, Western; Calcium; Chronic Disease; Female; Hypertension, Pulmonary; Monocrotaline; Muscle Contraction; Muscle, Smooth, Vascular; Myography; Piperidines; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Pulmonary Artery; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Up-Regulation; Xanthines

Topics: Animals; Calcium Signaling; Chronic Disease; Disease Models, Animal; Focal Adhesion Kinase 1; Hypertension, Pulmonary; Hypoxia; Integrins; Male; Monocrotaline; Muscle, Smooth, Vascular; Phosphorylation; Pulmonary Artery; Rats; Rats, Wistar

Topics: Animals; Chronic Disease; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Rats; Rats, Wistar; Tunica Media

Topics: Animals; Chronic Disease; Hypertension, Pulmonary; Inflammation; Male; Monocrotaline; Protein Kinase C; Pulmonary Artery; Rats; Rats, Wistar

Topics: Animals; Chronic Disease; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Hypertension; Hypoxia; Lung; Male; Monocrotaline; Neoplasm Proteins; Phosphorylation; Proteome; Pulmonary Artery; Rats; Rats, Sprague-Dawley

Topics: Animals; Cardiomyopathies; Chronic Disease; Dietary Proteins; Energy Intake; Female; Kidney Diseases; Male; Monocrotaline; Nutritional Physiological Phenomena; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Inbred Strains; Toxicology

Topics: Animals; Arterioles; Chronic Disease; Female; Hypertension, Pulmonary; Hypoxia; Lung; Monocrotaline; Pulmonary Artery; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Venules

Topics: Acute Disease; Animals; Blood Volume; Cardiovascular System; Chronic Disease; Gases; Hematocrit; Hemodynamics; Hemorrhage; Hypertrophy, Right Ventricular; Hypoxia; Male; Monocrotaline; Rats; Rats, Sprague-Dawley

Topics: Aerosols; Animals; Chronic Disease; Drug Combinations; Hypertension, Pulmonary; Male; Monocrotaline; Nitric Oxide; Perfusion; Polyamines; Rats; Rats, Sprague-Dawley; Vasoconstriction

Topics: Animals; Blood Flow Velocity; Chronic Disease; Disease Models, Animal; Dogs; Fourier Analysis; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Pulmonary Wedge Pressure; Signal Processing, Computer-Assisted; Ultrasonography; Vascular Resistance

Topics: Animals; Cardiotonic Agents; Chronic Disease; Dogs; Fourier Analysis; Hypertension, Pulmonary; Milrinone; Monocrotaline; Pulmonary Circulation; Pulmonary Wedge Pressure; Pyridones; Signal Processing, Computer-Assisted; Ultrasonography; Vascular Resistance; Vasodilator Agents; Ventricular Function, Right

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine Vasopressin; Blood Pressure; Chronic Disease; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Ionomycin; Lung; Male; Monocrotaline; Nitric Oxide Synthase; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents

Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Fourier Analysis; Hemodynamics; Hypertension, Pulmonary; Lung; Monocrotaline; Nitric Acid; Pulmonary Artery; Regional Blood Flow; Ventricular Function, Left

Topics: Age Factors; Animals; Catheterization, Swan-Ganz; Chronic Disease; Disease Models, Animal; Dogs; Heart-Lung Transplantation; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Reproducibility of Results; Ventricular Function

Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Electric Impedance; Fourier Analysis; Heart Transplantation; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Poisons; Prospective Studies; Pulmonary Artery

Topics: Animals; Chronic Disease; Endothelial Growth Factors; Gene Expression; Hypoxia; Lung; Lymphokines; Monocrotaline; Myocardium; Rats; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: Animals; Chronic Disease; Endothelial Growth Factors; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Lymphokines; Male; Monocrotaline; Myocardium; Organ Size; Rats; Rats, Wistar; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: Administration, Inhalation; Animals; Blood Pressure; Chronic Disease; Drug Synergism; Epoprostenol; Hypertension, Pulmonary; Male; Monocrotaline; Nitric Oxide; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasodilation

Topics: Adaptation, Physiological; Adenylyl Cyclases; Animals; Chronic Disease; Dogs; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Myocardium; Pulmonary Circulation; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stroke Volume; Ventricular Function, Right

Topics: Animals; Apoptosis; Atrophy; Blotting, Western; Body Weight; Caspase 3; Caspases; Cell Nucleus; Chronic Disease; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Male; Monocrotaline; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Ubiquitins

Topics: Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Chronic Disease; Dicarboxylic Acids; Dihydropyridines; Endothelins; Hemodynamics; Hypertension, Pulmonary; Male; Malondialdehyde; Monocrotaline; Muscle, Smooth, Vascular; Nitrendipine; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Serotonin; Superoxide Dismutase; Vasoconstriction

Topics: Animals; Chronic Disease; Female; Fenclonine; Hypertension, Pulmonary; Hypoxia; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin