monocrotaline and Chemical and Drug Induced Liver Injury

monocrotaline has been researched along with Chemical and Drug Induced Liver Injury in 34 studies

Research

Studies (34)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (8.82)	18.7374
1990's	2 (5.88)	18.2507
2000's	9 (26.47)	29.6817
2010's	18 (52.94)	24.3611
2020's	2 (5.88)	2.80

Authors

Authors	Studies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cao, Y; Chen, J; Gong, L; Liu, M; Qi, X; Ren, J; Sun, J; Wang, W; Wu, S; Xu, J	1
Betto, T; Inoue, T; Ito, Y; Koizumi, W; Kojo, K; Majima, M; Narumiya, S; Nishizawa, N; Ohkubo, H; Otaka, F; Yamane, S	1
Dai, YG; Fan, CP; Guo, Q; Guo, Y; Liu, J; Qiu, SK; Sun, XX; Wang, H; Wang, YQ; Xiang, E	1
Hata, S; Itoh, M; Itoh, T; Miyajima, A; Miyamura, N; Nishina, H; Nishio, M; Ogawa, Y; Sakaida, I; Suzuki, A; Tanaka, M; Terai, S	1
Chen, M; Huang, Z; Ji, L; Sheng, Y; Zhang, J	1
Guo, Y; Hu, S; Kou, H; Li, X; Wang, H; Wu, P; Xiao, D; Yang, X; Zheng, J	1
Fang, Y; Guo, Y; Li, X; Luo, J; Qiu, S; Wang, H; Wang, Y; Xiang, E; Yang, X; Zhang, L; Zheng, J	1
Ji, L; Li, L; Sheng, Y; Wei, M; Yang, F; Yang, R	1
Barros, SS; Borges, AS; Colegate, SM; Maia, LA; Medeiros, RM; Pessoa, AF; Pessoa, CR; Riet-Correa, F; Soares, MP	1
Colegate, SM; Dantas, AF; de Lucena, RB; Maia, LA; Nobre, VM; Riet-Correa, F	1
Al-muzafar, HM; Amin, KA; Hashem, KS; Taha, EM	1
Mori, K; Saitoh, W; Takasaki, W; Watanabe, K; Yamauchi, S	1
Canbaz, HT; Cuce, G; Kalkan, S; Sozen, ME; Yerlikaya, FH	1
Dai, W; Guan, X; Jiang, Y; Ma, Y; Qin, M; Shen, B; Wang, H; Zhang, Q; Zhang, Y	1
Abdel-Bakky, MS; Ashfaq, MK; Hammad, MA; Walker, LA	2
Amin, KA; Awad, el-ST; Hashem, KS; Hassan, MS	1
Alhussaini, AA; Bogaard, HJ; Farkas, D; Farkas, L; Gomez-Arroyo, JG; Kraskauskas, D; Voelkel, NF	1
Fujise, N; Imai, E; Masunaga, H; Yamashita, Y	1
Copple, BL; Ganey, PE; Hanumegowda, UM; Roth, RA; Shibuya, M; Yee, SB	1
Ganey, PE; Harkema, JR; Roth, RA; Yee, SB	1
Copple, BL; Ganey, PE; Roth, RA	2
LALICH, JJ	1
Bae, SH; Jung, Y; Oh, SH; Petersen, BE; Piscaglia, AC; Witek, RP; Zheng, D	1
Carvalho, I; Curti, C; da Silva, CH; da Silva, VB; Dorta, DJ; dos Santos, AB; dos Santos, AC; Mingatto, FE; Uyemura, SA	1
Mattocks, AR	1
Baybutt, RC; Molteni, A	1
Banes, A; Copple, BL; Ganey, PE; Roth, RA; Woolley, B	1
Baybutt, RC; Brady, H; Molteni, A; Rosales, C	1
Dhawan, BN; Dwivedi, Y; Garg, NK; Mehrotra, R; Rastogi, R; Sharma, SK	1
Dalvi, RR	1

Reviews

1 review(s) available for monocrotaline and Chemical and Drug Induced Liver Injury

Article	Year
The monocrotaline model of pulmonary hypertension in perspective. American journal of physiology. Lung cellular and molecular physiology, 2012, Feb-15, Volume: 302, Issue:4 Topics: Acute Lung Injury; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Humans; Hypertension, Pulmonary; Lung; Monocrotaline; Myocarditis	2012

Other Studies

33 other study(ies) available for monocrotaline and Chemical and Drug Induced Liver Injury

Article	Year
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Kupffer cells play a crucial role in monocrotaline-induced liver injury by producing TNF-α. Toxicology, 2022, 02-28, Volume: 468 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Hemagglutinins; Kupffer Cells; Male; Mice; Mice, Inbred BALB C; Monocrotaline; Tumor Necrosis Factor-alpha	2022
Thromboxane A Toxicology and applied pharmacology, 2019, 10-15, Volume: 381 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Endothelial Cells; Male; Mice, Inbred C57BL; Mice, Knockout; Monocrotaline; Receptors, Thromboxane; Signal Transduction	2019
Female-specific activation of pregnane X receptor mediates sex difference in fetal hepatotoxicity by prenatal monocrotaline exposure. Toxicology and applied pharmacology, 2020, 11-01, Volume: 406 Topics: Animals; Cell Line; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Female; Fetal Development; Fetus; Gene Expression Regulation; Humans; Liver; Male; Maternal-Fetal Exchange; Monocrotaline; Pregnancy; Pregnane X Receptor; Rats, Wistar; Sex Characteristics	2020
YAP determines the cell fate of injured mouse hepatocytes in vivo. Nature communications, 2017, 07-06, Volume: 8 Topics: Adaptor Proteins, Signal Transducing; Animals; Carbon Tetrachloride; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Movement; Chemical and Drug Induced Liver Injury; Ethanol; Fluorescent Antibody Technique; Gene Expression Regulation; Hepatocytes; Hippo Signaling Pathway; Kupffer Cells; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Monocrotaline; Phagocytosis; Phosphoproteins; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Signal Transduction; YAP-Signaling Proteins	2017
Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice. Toxicology and applied pharmacology, 2017, 10-15, Volume: 333 Topics: Animals; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; History, 18th Century; Immunity, Innate; Liver; Male; Mice, Inbred C57BL; Microarray Analysis; MicroRNAs; Monocrotaline; RNA, Messenger; Signal Transduction; Transcriptome	2017
Prenatal exposure to pyrrolizidine alkaloids induced hepatotoxicity and pulmonary injury in fetal rats. Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 85 Topics: Animals; Chemical and Drug Induced Liver Injury; Female; Fetal Growth Retardation; Fetus; Liver; Lung; Lung Injury; Maternal-Fetal Exchange; Monocrotaline; Pregnancy; Prenatal Injuries; Pyrrolizidine Alkaloids; Rats, Wistar	2019
Sex difference in monocrotaline-induced developmental toxicity and fetal hepatotoxicity in rats. Toxicology, 2019, 04-15, Volume: 418 Topics: Activation, Metabolic; Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Enzyme Induction; Female; Gestational Age; Liver; Male; Monocrotaline; Pregnancy; Rats, Wistar; Risk Assessment; Sex Factors	2019
Identification of serum microRNAs as potential toxicological biomarkers for toosendanin-induced liver injury in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 58 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Heterocyclic Compounds, 4 or More Rings; Liver; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; MicroRNAs; Monocrotaline; Random Allocation; Specific Pathogen-Free Organisms	2019
Pulmonary and hepatic lesions caused by the dehydropyrrolizidine alkaloid-producing plants Crotalaria juncea and Crotalaria retusa in donkeys. Toxicon : official journal of the International Society on Toxinology, 2013, Volume: 71 Topics: Animals; Cell Proliferation; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Crotalaria; Equidae; Fibrosis; Liver; Lung; Lung Diseases; Monocrotaline; Plant Poisoning; Pyrrolizidine Alkaloids; Seeds	2013
Natural and experimental poisoning of goats with the pyrrolizidine alkaloid-producing plant Crotalaria retusa L. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2013, Volume: 25, Issue:5 Topics: Animals; Brazil; Chemical and Drug Induced Liver Injury; Crotalaria; Disease Outbreaks; Goat Diseases; Goats; Histocytochemistry; Monocrotaline; Seeds	2013
Oxidative hepatotoxicity effects of monocrotaline and its amelioration by lipoic acid, S-adenosyl methionine and vitamin E. Journal of complementary & integrative medicine, 2014, Jan-10, Volume: 11, Issue:1 Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Monocrotaline; Oxidants; Oxidative Stress; Oxidoreductases; Rats; S-Adenosylmethionine; Thioctic Acid; Vitamin E	2014
Metabolomic analysis of arginine metabolism in acute hepatic injury in rats. The Journal of toxicological sciences, 2014, Volume: 39, Issue:1 Topics: Alanine Transaminase; Animals; Arginase; Arginine; Biomarkers; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Isocyanates; Male; Metabolomics; Monocrotaline; Naphthalenes; Ornithine; Rats; Rats, Inbred F344; Tetramethylphenylenediamine	2014
Vitamin E and selenium treatment of monocrotaline induced hepatotoxicity in rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission, 2017, Volume: 92, Issue:1 Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Female; Monocrotaline; Rats; Rats, Wistar; Selenium; Vitamin E	2017
An effective ex-vivo approach for inducing endothelial progenitor cells from umbilical cord blood CD34 Stem cell research & therapy, 2017, 02-07, Volume: 8, Issue:1 Topics: Animals; Antigens, CD; Biomarkers; Cadherins; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Chemical and Drug Induced Liver Injury; Culture Media; Endothelial Progenitor Cells; Factor VIII; Fetal Blood; Gene Expression; Humans; Liver; Male; Mice; Mice, Inbred NOD; Mice, SCID; Monocrotaline; Platelet Endothelial Cell Adhesion Molecule-1; Primary Cell Culture; Transplantation, Heterologous; von Willebrand Factor	2017
Oxidized low-density lipoprotein and tissue factor are involved in monocrotaline/lipopolysaccharide-induced hepatotoxicity. Archives of toxicology, 2011, Volume: 85, Issue:9 Topics: Alanine Transaminase; Animals; Cell Culture Techniques; Chemical and Drug Induced Liver Injury; Chemokine CXCL16; Chemokine CXCL6; Chemokines, CXC; Collagen; Data Interpretation, Statistical; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hep G2 Cells; Humans; Lipopolysaccharides; Lipoproteins, LDL; Liver; Male; Mice; Mice, Inbred Strains; Monocrotaline; Oxidation-Reduction; Receptors, Scavenger; Thromboplastin	2011
The protective effects of cerium oxide nanoparticles against hepatic oxidative damage induced by monocrotaline. International journal of nanomedicine, 2011, Jan-17, Volume: 6 Topics: Analysis of Variance; Animals; Catalase; Cerium; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Histocytochemistry; Liver; Male; Microscopy, Electron; Monocrotaline; Nanoparticles; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Superoxide Dismutase	2011
Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice. Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:8 Topics: Alanine Transaminase; Animals; Blood Coagulation; Chemical and Drug Induced Liver Injury; Chemokines; Cytokines; Hematocrit; Lipid Metabolism; Lipopolysaccharides; Lipoproteins, LDL; Liver; Male; Mice; Monocrotaline; Oligonucleotides, Antisense; Thromboplastin	2013
Reduction of monocrotaline-induced hepatic injury by deleted variant of hepatocyte growth factor (dHGF) in rats. Liver, 2002, Volume: 22, Issue:4 Topics: Administration, Oral; Animals; Chemical and Drug Induced Liver Injury; Clinical Chemistry Tests; Hepatocyte Growth Factor; Male; Monocrotaline; Protein Isoforms; Rats; Rats, Sprague-Dawley	2002
Endothelial cell injury and coagulation system activation during synergistic hepatotoxicity from monocrotaline and bacterial lipopolysaccharide coexposure. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:1 Topics: Animals; Blood Coagulation; Chemical and Drug Induced Liver Injury; Drug Synergism; Endothelial Cells; Fibrin; Fibrinogen; Hemoglobins; Immunoblotting; Immunohistochemistry; Lipopolysaccharides; Male; Microscopy, Electron, Scanning; Microsomes, Liver; Monocrotaline; Poisons; Pyrroles; Rats; Rats, Sprague-Dawley	2003
The coagulation system contributes to synergistic liver injury from exposure to monocrotaline and bacterial lipopolysaccharide. Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:2 Topics: Animals; Anticoagulants; Blood Coagulation; Chemical and Drug Induced Liver Injury; Drug Antagonism; Drug Synergism; Escherichia coli; Heparin; Lipopolysaccharides; Male; Monocrotaline; Neutropenia; Neutrophils; Rats; Rats, Sprague-Dawley; Warfarin	2003
Liver inflammation during monocrotaline hepatotoxicity. Toxicology, 2003, Aug-28, Volume: 190, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Chemokine CCL2; Chemokine CXCL1; Chemokine CXCL2; Chemokines; Chemokines, CXC; Chemotactic Factors; Enzyme Inhibitors; Gadolinium; Heparin; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kupffer Cells; Male; Monocrotaline; Monokines; Neutrophils; Pentoxifylline; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation	2003
INFLUENCE OF RAT STRAIN ON PULMONARY VASCULAR RESPONSES TO MONOCROTALINE FEEDING. Pathologia et microbiologia, 1964, Volume: 27 Topics: Alkaloids; Arteritis; Chemical and Drug Induced Liver Injury; Genetics; Hemorrhage; Hepatitis; Monocrotaline; Pathology; Pulmonary Artery; Pulmonary Embolism; Rats; Research; Toxicology	1964
Anticoagulation and inhibition of nitric oxide synthase influence hepatic hypoxia after monocrotaline exposure. Toxicology, 2006, Aug-15, Volume: 225, Issue:2-3 Topics: Animals; Anticoagulants; Cell Hypoxia; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Fibrinogen; Hyaluronic Acid; Liver; Male; Monocrotaline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Warfarin	2006
Bone marrow-derived hepatic oval cells differentiate into hepatocytes in 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration. Gastroenterology, 2007, Volume: 132, Issue:3 Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Animals, Genetically Modified; Antimitotic Agents; Bone Marrow Cells; Bone Marrow Transplantation; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dipeptidyl Peptidase 4; Disease Models, Animal; Female; Hepatectomy; Hepatocytes; Liver; Liver Diseases; Liver Regeneration; Male; Monocrotaline; Rats; Rats, Inbred F344; Stem Cells; Time Factors; X Chromosome; Y Chromosome	2007
Dehydromonocrotaline inhibits mitochondrial complex I. A potential mechanism accounting for hepatotoxicity of monocrotaline. Toxicon : official journal of the International Society on Toxinology, 2007, Volume: 50, Issue:5 Topics: Adenosine Triphosphate; Alkylating Agents; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Electron Transport Complex I; Enzyme Inhibitors; Male; Membrane Potential, Mitochondrial; Mitochondria, Liver; Monocrotaline; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxygen Consumption; Rats; Rats, Wistar; Submitochondrial Particles	2007
Hydrolysis and hepatotoxicity of retronecine diesters. Toxicology letters, 1982, Volume: 14, Issue:1-2 Topics: Animals; Chemical and Drug Induced Liver Injury; Hydrolysis; Kinetics; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains	1982
Dietary beta-carotene protects lung and liver parenchyma of rats treated with monocrotaline. Toxicology, 1999, Sep-20, Volume: 137, Issue:2 Topics: Animals; Antidotes; Antioxidants; beta Carotene; Chemical and Drug Induced Liver Injury; Collagen; Diet; Fatty Liver; Hemorrhage; Hypertrophy, Right Ventricular; Liver; Lung; Lung Diseases; Male; Monocrotaline; Poisons; Rats; Rats, Sprague-Dawley	1999
Anticoagulants prevent monocrotaline-induced hepatic parenchymal cell injury but not endothelial cell injury in the rat. Toxicology and applied pharmacology, 2002, May-01, Volume: 180, Issue:3 Topics: Analysis of Variance; Animals; Anticoagulants; Chemical and Drug Induced Liver Injury; Endothelium; Fibrin; Heparin; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Warfarin	2002
Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats. Toxicology, 2002, Jun-14, Volume: 175, Issue:1-3 Topics: Animals; Chemical and Drug Induced Liver Injury; Dietary Fats; Fatty Acids, Unsaturated; Fish Oils; Histocytochemistry; Hypertrophy, Right Ventricular; Liver; Liver Cirrhosis; Lung; Male; Monocrotaline; Pneumonia; Pulmonary Fibrosis; Random Allocation; Rats; Rats, Sprague-Dawley	2002
Picroliv protects against monocrotaline-induced hepatic damage in rats. Pharmacological research, 1991, Volume: 23, Issue:4 Topics: Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Liver Diseases; Male; Monocrotaline; Plant Extracts; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vanillic Acid	1991
Dose-related inhibition of the drug-metabolizing enzymes of rat liver by the pyrrolizidine alkaloid, monocrotaline. The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:5 Topics: Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Liver Diseases; Male; Microsomes, Liver; Monocrotaline; Oxidoreductases; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Transaminases	1987