monocrotaline has been researched along with Cardiac Failure in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (2.22) | 18.7374 |
| 1990's | 14 (15.56) | 18.2507 |
| 2000's | 30 (33.33) | 29.6817 |
| 2010's | 27 (30.00) | 24.3611 |
| 2020's | 17 (18.89) | 2.80 |
| Authors | Studies |
|---|---|
| Alothman, AA; Arumugam, R; Atallah, MM; Bagheri, D; Cui, M; El-Sabbagh, NM; El-Sayed, NS; Ghafarifarsani, H; Ghetas, HA; Hedayati, SA; Hosseini Shekarabi, SP; Inoue, Y; Khalil, RH; Khallaf, MM; Kuroda, Y; Kuznetsov, D; Lee, J; Lookin, O; Nam, YW; Nemoto, H; Nguyen, M; Noda, M; Numaguchi, R; Orfali, R; Priscillal, IJD; Protsenko, Y; Rahman, MA; Shahbazi Naserabad, S; Shakweer, MS; Sheikh Veisi, R; Takahashi, K; Tanaka, C; Wada, K; Wang, SF; Yang, G; Yoshino, K; Zhang, M | 1 |
| Crossman, DJ; Han, JC; Howe, K; Loiselle, DS; Ross, JM | 1 |
| Bagchi, AK; Farahmand, F; Malik, A; Sharma, A; Singal, PK | 1 |
| Goshima, Y; Goto, T; Hashimoto, T; Koga, M; Masukawa, D; Matsushita, N; Miyazaki, T; Mizuno, Y; Nakamura, F; Nakano, M; Niikura, R; Saito, M; Shimizu, T; Tamura, K; Uchimura, H; Zou, S | 1 |
| Al-Qazazi, R; Archer, SL; Bentley, RET; Bonnet, S; Chen, KH; Dasgupta, A; Jones, O; Lima, PDA; Martin, AY; Maurice, DH; Mewburn, J; Potus, F; Prins, KW; Prisco, SZ; Provencher, S; Tian, L; Wu, D | 1 |
| Bisserier, M; Bonnet, S; Boucherat, O; Hadri, L | 1 |
| Chang, R; Cui, B; Fan, Z; Hiram, R; Huang, C; Huang, H; Liu, T; Shi, S; Su, X; Tang, Y; Wu, G; Wu, J; Xiong, F; Yan, M; Zhang, W | 1 |
| Colyer, J; Hurley, ME; Jayasinghe, I; Sheard, TMD; Smith, AJ; White, E | 1 |
| Boehm, M; Bonnet, S; Bourgeois, A; Dabral, S; de Man, F; Friedrich, A; Grobs, Y; Guenther, S; Jafari, L; Janssen, W; Khassafi, F; Kojonazarov, B; Kuenne, C; Looso, M; Maroli, G; Nayakanti, SR; Provencher, S; Pullamsetti, SS; Sarode, P; Savai, R; Schermuly, RT; Seeger, W; Tello, K; Weiss, A; Wietelmann, A; Wilhelm, J | 1 |
| Cui, L; Li, L; Ma, Q; Mou, J; Sun, G; Wang, M; Zhang, Q; Zhang, X | 1 |
| Baranowska-Kuczko, M; Kasacka, I; Kozłowska, H; Krzyżewska, A | 1 |
| Frede, W; Freichel, M; Gorenflo, M; Medert, R; Poth, T; Uhl, S; Vennekens, R | 1 |
| Fan, Z; Geng, W; Gu, J; Long, J; Shao, L; Wan, Q; Wang, Y; Wei, C; Xuan, L; Zhao, M | 1 |
| Araujo, ASDR; Bassani, VL; Belló-Klein, A; Bianchi, S; Campos-Carraro, C; de Castro, AL; Hickmann, A; Lacerda, D; Ortiz, V; Türck, P | 1 |
| Banerjee, S; Clark, VR; Fishbein, G; Hong, J; Park, JF; Razee, A; Saddic, L; Umar, S; Williams, T | 1 |
| Dignam, JP; Hobbs, AJ; Kemp-Harper, BK; Scott, TE | 1 |
| Fan, J; Lv, Y; Ma, P; Wang, J; Xu, Q; Yan, L; Zhou, R | 1 |
| Gu, Q; Hao, Y; Liu, N; Qu, C; Xu, Y; Yan, Y; Yang, X | 1 |
| Crossman, DJ; Hickey, AJ; Loiselle, DS; Power, AS; Ward, ML | 1 |
| Balakin, A; Lookin, O; Protsenko, Y | 1 |
| Cao, Y; Dai, S; Gao, X; Guo, Q; Li, L; Peng, YG; Wang, E; Wang, L; Yang, Y; Zhang, J; Zhang, Y | 1 |
| Lookin, O; Protsenko, Y | 1 |
| Chen, F; Chen, L; Meng, H; Wang, H; Yan, J; Yuan, L; Zhan, H; Zhao, J | 1 |
| Hickey, AJ; Jones, TLM; Norman, R; Power, AS; Ward, ML | 1 |
| Boyle, J; Egginton, S; Fowler, ED; Hauton, D; Steele, DS; White, E | 1 |
| Bartelds, B; Berger, RM; Borgdorff, MA; de Vroomen, M; Dickinson, MG; Steendijk, P | 1 |
| Bonneu, M; Claverol, S; Crevel, H; Delom, F; Fessart, D; Martin-Negrier, ML; Muller, B; Savineau, JP; Thiolat, ML; Toussaint, C | 1 |
| Carlebur, M; Davenport, AP; Kuc, RE; Long, L; Maguire, JJ; Morrell, NW; Toshner, M; Yang, P | 1 |
| Balestra, GM; Eerbeek, O; Mik, EG; Specht, PA; van der Laarse, WJ; Zuurbier, CJ | 1 |
| Hanawa, H; Hayashi, Y; Jiao, S; Kashimura, T; Minamino, T; Obata, H; Ohno, Y; Suzuki, T; Tanaka, K; Watanabe, T; Yoshida, K | 1 |
| Balakin, A; Kuznetsov, D; Lookin, O; Protsenko, Y | 1 |
| Jiang, Y; Ye, L; Zuo, X | 1 |
| Boyle, JP; Calaghan, SC; Deuchars, J; Frater, B; Hardy, ME; Kirton, HM; MacDougall, DA; Peers, C; Ponnambalam, S; Steele, DS; White, E; Yang, Z | 1 |
| Andreu, AL; Barreiro, E; Chacón-Cabrera, A; García-Arumí, E; Marin-Corral, J; Mateu, X; Molina, L; Puente-Maestu, L; Puig-Vilanova, E; Salazar-Degracia, A | 1 |
| Deie, M; Fujino, H; Fujita, N; Sakamoto, H; Takegaki, J | 1 |
| Imoto, K; Kumatani, S; Okada, M; Yamawaki, H | 1 |
| Carmo, EM; Carvalho, RF; Castoldi, RC; Mariano, TB; Okoshi, K; Ozaki, GA; Pacagnelli, FL; Sabela, AK; Tomasi, LC; Vanderlei, LC | 1 |
| Brandão-Nogueira, A; Correia-Pinto, J; Henriques-Coelho, T; Leite-Moreira, AF; Moreira-Gonçalves, D | 1 |
| de Man, FS; Handoko, ML; Happé, CM; Musters, RJ; Paulus, WJ; Postmus, PE; Schalij, I; van der Laarse, WJ; Vonk-Noordegraaf, A; Westerhof, N | 1 |
| Afrooziyan, A; Garjani, A; Kharazmkia, A; Maleki-Dizaji, N; Najafi, M; Nazemiyeh, H | 1 |
| den Adel, B; Hessel, M; Schutte, C; Steendijk, P; van der Laarse, A | 1 |
| Allaart, CP; Boer, C; de Man, FS; Handoko, ML; Lamberts, RR; Paulus, WJ; Redout, EM; Simonides, WS; Vonk-Noordegraaf, A; Westerhof, N | 1 |
| Abe, Y; Daicho, T; Marunouchi, T; Ohara, M; Takeo, S; Tanonaka, K; Yagi, T | 1 |
| Daicho, T; Daisho, Y; Kojima, S; Marunouchi, T; Takagi, N; Takano, S; Takeo, S; Tanonaka, K; Tejima, Y | 1 |
| Musters, RJ; Paulus, WJ; Redout, EM; Simonides, WS; van de Kolk, CW; van der Toorn, A; van Echteld, CJ; van Hardeveld, C; Zuidwijk, MJ | 1 |
| Almeida, FL; Araújo, JP; Carvalho, RF; Castan, EP; Cicogna, AC; Coelho, CA; Dal Pai-Silva, M; de Souza, RW; Lopes, FS; Michelin, A | 1 |
| Campian, ME; de Bakker, JM; de Bruin, K; Hardziyenka, M; Tan, HL; van Eck-Smit, BL; Verberne, HJ | 1 |
| Bertaglia, RS; Carani, FR; Carvalho, RF; Cavalcante, WL; Cigogna, AC; Fernandes, AA; Gallacci, M; Lopes, FS; Padovani, CR; Reissler, J; Rodrigues, SA; Silva, MD | 1 |
| Bogaards, SJ; de Man, FS; Handoko, ML; Paulus, WJ; Postmus, PE; Schalij, I; van Ballegoij, JJ; van der Velden, J; Vonk-Noordegraaf, A; Westerhof, N | 1 |
| Anderson, ME; Chen, B; Grumbach, IM; Guo, A; Li, Y; Sanders, P; Song, LS; Wang, LC; Weiss, RM; Xie, YP; Zimmerman, K | 1 |
| Bouitbir, J; Charles, AL; Charloux, A; Enache, I; Favret, F; Geny, B; Metzger, D; Oswald-Mammosser, M; Zoll, J | 1 |
| Angelini, A; Carraro, U; Ceconi, C; Dalla Libera, L; Ravara, B; Sandri, M; Vescovo, G | 1 |
| Angelini, A; Calvani, M; Dalla Libera, L; Della Barbera, M; Dona, M; Gobbo, V; Mosconi, L; Peluso, G; Ravara, B; Sandri, M; Vescovo, G | 1 |
| Korstjens, IJ; Rouws, CH; Stienen, GJ; van der Laarse, WJ; Van der Zee, L | 1 |
| Beilfuss, A; Brandt, K; Brodde, OE; Heinroth-Hoffmann, I; Leineweber, K; Pönicke, K; Wludyka, B | 1 |
| Bernocchi, P; Boraso, A; Cargnoni, A; Ceconi, C; Dalla Libera, L; Ferrari, R; Parrinello, G; Vescovo, G | 1 |
| Bongrani, S; Cargnioni, A; Ferrari, R; Gitti, GL; Pasini, E; Pastore, F; Razzetti, R | 1 |
| Bonnet, S; Dyck, JR; Haromy, A; Hashimoto, K; McMurtry, MS; Michelakis, ED; Wu, X | 1 |
| Honjo, H; Kamiya, K; Kodama, I; Lee, JK; Nihei, M; Opthof, T; Uzzaman, M; Yasui, K | 1 |
| Chachques, JC; Monnet, E | 1 |
| Fujimori, A; Goto, K; Iemitsu, M; Miyauchi, T; Sakai, S; Sanagi, M; Shikama, H; Sudoh, K; Yamaguchi, I; Yuyama, H | 1 |
| Angelini, A; Dalla Libera, L; Danieli Betto, D; Germinario, E; Gobbo, V; Ravara, B; Vescovo, G | 1 |
| Endo, H; Hirose, M; Kagaya, Y; Miura, M; Nakano, M; Shimokawa, H; Shirato, K; Sugai, Y; Takahashi, J; Wakayama, Y; Watanabe, J | 1 |
| Minami, S; Miyazaki, H; Mochizuki, S; Ohsawa, S; Okazaki, F; Onodera, T | 1 |
| Campian, ME; de Bruin-Bon, HA; Hardziyenka, M; Michel, MC; Tan, HL | 1 |
| Carvalho, RF; Cicogna, AC; Dal Pai-Silva, M; Dariolli, R; Felisbino, SL; Justulin Junior, LA; Politi Okoshi, M; Sugizaki, MM | 1 |
| Fukuda, K; Ieda, M; Kanazawa, H; Kimura, K; Kurosawa, H; Mochizuki, H; Ninomiya, S; Ogawa, S; Tsunoda, M; Yagi, T; Yamazaki, K; Yoshimi, K | 1 |
| Atsma, D; Bax, W; Hessel, M; Schalij, M; Schutte, C; Steendijk, P; Umar, S; van der Laarse, A; van der Wall, E | 1 |
| Bertipaglia, L; Calò, LA; Corradini, R; Dalla Libera, L; Davis, PA; Naso, A; Pagnin, E; Piccoli, A; Savica, V; Spinello, M | 1 |
| Enomoto, K; Honda, M; Ishinaga, Y; Kuramochi, T; Kuzuo, H; Morioka, S; Takabatake, T; Tanaka, K | 1 |
| Enomoto, K; Hashimoto, M; Honda, M; Kuramochi, T; Morioka, S; Tanaka, K | 1 |
| Agnoletti, G; Albertini, A; Comini, L; Ferrari, R; Gaia, G; Mantero, G; Panzali, A; Pasini, E | 1 |
| Bachetti, T; Benigno, M; Ceconi, C; Comini, L; Curello, S; Ferrari, R; Gaia, G; Pasini, E | 1 |
| Agnoletti, L; Bachetti, T; Ceconi, C; Comini, L; Curello, S; Ferrari, R; Gaia, G; Pasini, E; Pepi, P | 1 |
| Bernocchi, P; Ceconi, C; Curello, S; Ferrari, R; Pasini, E; Pedersini, P | 1 |
| Bongrazio, M; Cargnoni, A; Comini, L; Ferrari, R; Gaia, G; Pasini, E; Visioli, O | 1 |
| Ambrosio, GB; Libera, LD; Sandri, M; Vescovo, G; Zennaro, R | 1 |
| Bernocchi, P; Ceconi, C; de Jong, JW; de Jonge, R; Harrison, R; Keijzer, E; Schoemaker, RG; Sharma, HS | 1 |
| Brodde, OE; Leineweber, K; Seyfarth, T | 1 |
| Angelini, A; Battista Ambrosio, G; Dalla Libera, L; Ravara, B; Rossini, K; Sandri, M; Thiene, G; Vescovo, G | 1 |
| Ambrosio, GB; Dalla Libera, L; Vescovo, G | 1 |
| Chakrabarti, S; Chen, L; Feng, Q; Gan, XT; Haist, JV; Karmazyn, M; Lu, X | 1 |
| Hashimoto, H; Ito, T; Kondo, J; Okumura, K; Shimizu, K; Toki, Y; Yoshino, M | 1 |
| Honda, M; Ishikawa, S; Ishinaga, Y; Morioka, S; Moriyama, K; Tanaka, K; Yano, S | 1 |
| Honda, M; Ishikawa, S; Morioka, S; Moriyama, K; Yamada, S | 1 |
| Hashimoto, H; Ito, T; Okumura, K; Satake, T; Yamada, Y | 1 |
| Guarnieri, C; Muscari, C | 1 |
| Agnoletti, G; Cornacchiari, A; De Giuli, F; Ferrari, R; Ghielmi, S; Panzali, AF | 1 |
| Ceconi, C; Condorelli, E; Ferrari, R; Harris, P; Quinzanini, M; Rodella, A | 1 |
| Harding, SE; Jones, SM; Poole-Wilson, PA; Vescovo, G | 1 |
3 review(s) available for monocrotaline and Cardiac Failure
| Article | Year |
|---|---|
Animal models of pulmonary hypertension: Getting to the heart of the problem.
Topics: Animals; Disease Models, Animal; Heart Failure; Humans; Hypertension, Pulmonary; Monocrotaline; Pulmonary Artery; Ventricular Dysfunction, Right; Ventricular Function, Right | 2022 |
Animal models of heart failure: what is new?
Topics: Animals; Blood Pressure; Cardiac Volume; Cardiomyopathy, Dilated; Disease Models, Animal; Doxorubicin; Heart Failure; Humans; Imipramine; Ligation; Monocrotaline; Myocardial Ischemia | 2005 |
Apoptosis and changes in contractile protein pattern in the skeletal muscle in heart failure.
Topics: Angiotensin Receptor Antagonists; Animals; Apoptosis; Biphenyl Compounds; Contractile Proteins; Disease Models, Animal; Heart Failure; Humans; Irbesartan; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Rats; Sphingosine; Tetrazoles; Tumor Necrosis Factor-alpha | 2001 |
2 trial(s) available for monocrotaline and Cardiac Failure
| Article | Year |
|---|---|
Topics: Aeromonas hydrophila; Animal Feed; Animals; Antioxidants; Cadmium Chloride; Calmodulin; Cardiotonic Agents; Carps; Cichlids; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Fish Diseases; Heart; Heart Failure; Lacticaseibacillus casei; Liver; Magnetic Iron Oxide Nanoparticles; Male; Monocrotaline; Mutagenesis, Site-Directed; Myocardial Contraction; Oxidative Stress; Potassium Channels, Calcium-Activated; Rats; Rats, Wistar; Urea; Withania | 2021 |
Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium handling.
Topics: Animals; Arrhythmias, Cardiac; Benzhydryl Compounds; Calcium; Connexin 43; Disease Models, Animal; Fura-2; Glucose; Glucosides; Heart Failure; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Sodium; Ventricular Dysfunction, Right; Ventricular Remodeling | 2022 |
85 other study(ies) available for monocrotaline and Cardiac Failure
| Article | Year |
|---|---|
Right-sided heart failure is also associated with transverse tubule remodeling in the left ventricle.
Topics: Animals; Calcium Signaling; Disease Models, Animal; Heart Failure; Heart Ventricles; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Male; Membrane Proteins; Monocrotaline; Rats, Wistar; Ryanodine Receptor Calcium Release Channel; Sarcomeres; Ventricular Function, Left; Ventricular Function, Right; Ventricular Remodeling | 2021 |
Role of oxidative stress versus lipids in monocrotaline-induced pulmonary hypertension and right heart failure.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Catalase; Echocardiography; Glutathione Peroxidase; Heart; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Lipid Peroxidation; Lovastatin; Lung; Monocrotaline; Myocardium; Organ Size; Oxidative Stress; Probucol; Rats; Superoxide Dismutase; Ventricular Dysfunction, Right | 2021 |
Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Pulmonary Artery; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Systole; Vasoconstriction; Ventricular Dysfunction, Right; Ventricular Function, Right | 2022 |
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
Topics: Animals; Atrial Natriuretic Factor; Cytokine Receptor gp130; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Fibrosis; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inflammasomes; Macrophage Activation; Macrophages; Monocrotaline; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Arterial Hypertension; Rats; Ventricular Dysfunction, Right | 2022 |
Intra-Airway Gene Delivery for Pulmonary Hypertension in Rodent Models.
Topics: Animals; Disease Models, Animal; Genetic Therapy; Heart Failure; Humans; Hypertension, Pulmonary; Monocrotaline; Pulmonary Artery; Rats; Rodentia | 2022 |
Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads.
Topics: Animals; Calcium; Calcium Signaling; Heart Failure; Imaging, Three-Dimensional; Monocrotaline; Rats; Ryanodine Receptor Calcium Release Channel | 2022 |
Targeting Wnt-ß-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling.
Topics: Animals; beta Catenin; Catenins; Disease Models, Animal; Heart Failure; Mice; Monocrotaline; Pulmonary Arterial Hypertension; Rats; Signal Transduction; Ventricular Function, Right; Ventricular Remodeling | 2023 |
Jiedu Quyu Decoction mitigates monocrotaline-induced right-sided heart failure associated with pulmonary artery hypertension by inhibiting NLRP3 inflammasome in rats.
Topics: Animals; Biomarkers; Heart Failure; Hypertension, Pulmonary; Inflammasomes; Interleukin-18; Interleukin-1beta; Monocrotaline; NLR Family, Pyrin Domain-Containing 3 Protein; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2023 |
Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway in monocrotaline-induced pulmonary hypertension in rats.
Topics: Animals; Cannabidiol; Fibronectins; Fibrosis; Heart Failure; Hypertension, Pulmonary; Monocrotaline; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2023 |
TRPM4 Modulates Right Ventricular Remodeling Under Pressure Load Accompanied With Decreased Expression Level.
Topics: Animals; Child; Heart Failure; Humans; Hypertrophy, Right Ventricular; Mice; Monocrotaline; Rats; Rats, Wistar; TRPM Cation Channels; Ventricular Function, Right; Ventricular Remodeling | 2020 |
Trapidil determines the fate of RHF rats through inhibition of ER stress.
Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Heart Failure; Injections, Intraperitoneal; Male; Monocrotaline; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Trapidil | 2020 |
Pterostilbene improves cardiac function in a rat model of right heart failure through modulation of calcium handling proteins and oxidative stress.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antioxidants; Calcium; Echocardiography; Glutathione; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Lipid Peroxidation; Male; Monocrotaline; Oxidative Stress; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stilbenes; Stroke Volume | 2020 |
Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension: Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Animals; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Heart Failure; Heart Ventricles; Humans; Hypoxia; Indoles; Male; Middle Aged; Monocrotaline; Pulmonary Arterial Hypertension; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; RNA-Seq; Transcriptome; Ventricular Dysfunction, Right; Ventricular Remodeling | 2021 |
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Topics: Actins; Administration, Oral; Animals; Apoptosis; Arterioles; Betaine; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; Heart Failure; Heart Ventricles; Male; Monocrotaline; Proliferating Cell Nuclear Antigen; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Vascular Remodeling | 2021 |
PPARγ Alleviates Right Ventricular Failure Secondary to Pulmonary Arterial Hypertension in Rats.
Topics: Animals; Apoptosis; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelial Cells; Heart Failure; Hypertension, Pulmonary; Lipid Metabolism; Male; Monocrotaline; Myocytes, Cardiac; PPAR gamma; Random Allocation; Rats, Sprague-Dawley | 2017 |
Calcium mishandling impairs contraction in right ventricular hypertrophy prior to overt heart failure.
Topics: Animals; Calcium; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isoproterenol; Male; Monocrotaline; Myocardial Contraction; Rats; Rats, Wistar; Sarcoplasmic Reticulum | 2018 |
Inhibition of AT1 receptors by losartan affects myocardial slow force response in healthy but not in monocrotaline-treated young rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Female; Heart Failure; Losartan; Male; Monocrotaline; Myocardial Contraction; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2018 |
Analyses of long non-coding RNA and mRNA profiles in right ventricle myocardium of acute right heart failure in pulmonary arterial hypertension rats.
Topics: Animals; Computational Biology; Databases, Genetic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Lipopolysaccharides; Male; Monocrotaline; Rats, Sprague-Dawley; RNA, Long Noncoding; RNA, Messenger; Transcriptome; Ventricular Dysfunction, Right; Ventricular Function, Right | 2018 |
The lack of slow force response in failing rat myocardium: role of stretch-induced modulation of Ca-TnC kinetics.
Topics: Animals; Calcium; Female; Heart; Heart Failure; Heart Ventricles; Kinetics; Male; Monocrotaline; Myocardial Contraction; Myocardium; Rats; Rats, Wistar; Sodium; Sodium-Calcium Exchanger | 2019 |
Grape seed proanthocyanidin inhibits monocrotaline-induced pulmonary arterial hypertension via attenuating inflammation: in vivo and in vitro studies.
Topics: Animals; Calcium; Cell Proliferation; Cells, Cultured; Grape Seed Extract; Heart Failure; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Pneumonia; Proanthocyanidins; Pulmonary Arterial Hypertension; Rats, Sprague-Dawley; Vascular Remodeling | 2019 |
Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment.
Topics: Adenosine Triphosphatases; Administration, Oral; Adrenergic beta-1 Receptor Antagonists; Animals; Disease Models, Animal; Energy Metabolism; Heart Failure; Hypertension, Pulmonary; Male; Metoprolol; Mitochondria; Monocrotaline; Myocytes, Cardiac; Myofibrils; Oxidative Phosphorylation; Placebo Effect; Rats; Rats, Wistar; Reactive Oxygen Species; Ventricular Function, Right | 2019 |
Energy Metabolism in the Failing Right Ventricle: Limitations of Oxygen Delivery and the Creatine Kinase System.
Topics: Adrenergic beta-Antagonists; Animals; Creatine Kinase; Disease Models, Animal; Energy Metabolism; Enzyme Activation; Heart Failure; Hypertension, Pulmonary; Hypoxia; Male; Mitochondria; Monocrotaline; Muscle Cells; Oxygen; Rats; Ventricular Dysfunction, Right | 2019 |
Distinct loading conditions reveal various patterns of right ventricular adaptation.
Topics: Adaptation, Physiological; Animals; Arteriovenous Shunt, Surgical; Constriction; Disease Models, Animal; Familial Primary Pulmonary Hypertension; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Models, Cardiovascular; Monocrotaline; Myocardial Contraction; Physical Exertion; Pulmonary Artery; Rats; Rats, Wistar; Stroke Volume; Time Factors; Ultrasonography; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure | 2013 |
Proteomic remodeling of proteasome in right heart failure.
Topics: Animals; Gene Expression Profiling; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hypoxia; Male; Monocrotaline; Proteasome Endopeptidase Complex; Proteolysis; Proteome; Rats; Rats, Wistar; Signal Transduction; Ubiquitination; Ventricular Dysfunction, Right | 2014 |
Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension.
Topics: Animals; Autoradiography; Azepines; Binding, Competitive; Case-Control Studies; Heart Failure; Heart Ventricles; Humans; Hypertension, Pulmonary; Indoles; Kinetics; Lung; Male; Monocrotaline; Pulmonary Artery; Rats, Sprague-Dawley; Receptors, Endothelin | 2014 |
Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: mitochondrial inhibition as driver of cardiac failure?
Topics: Administration, Inhalation; Animals; Arterial Pressure; Cardiotonic Agents; Disease Models, Animal; Disease Progression; Dobutamine; Energy Metabolism; Heart Failure; Hexokinase; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; L-Lactate Dehydrogenase; Male; Mitochondria, Heart; Monocrotaline; Oxygen; Oxygen Consumption; Protoporphyrins; Pulmonary Artery; Rats, Wistar; Ventricular Dysfunction, Right; Ventricular Function, Right | 2015 |
Liver congestion in heart failure contributes to inappropriately increased serum hepcidin despite anemia.
Topics: Aged; Anemia; Animals; Biomarkers; Female; Heart Failure; Hepcidins; Humans; Iron; Liver Diseases; Male; Middle Aged; Monocrotaline; Organ Size; Oxygen; Prevalence; Rats, Inbred Lew | 2015 |
The length-dependent activation of contraction is equally impaired in impuberal male and female rats in monocrotaline-induced right ventricular failure.
Topics: Action Potentials; Age Factors; Animals; Calcium Signaling; Disease Models, Animal; Female; Heart Failure; Heart Ventricles; Isometric Contraction; Male; Monocrotaline; Myocardial Contraction; Rats, Wistar; Sex Factors; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right | 2015 |
Farnesoid-X-receptor expression in monocrotaline-induced pulmonary arterial hypertension and right heart failure.
Topics: Animals; Disease Models, Animal; Gene Expression; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Vascular Remodeling; Ventricular Remodeling | 2015 |
The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Golgi Apparatus; Guanine Nucleotide Exchange Factors; Heart Failure; Immunoblotting; Isoproterenol; Male; Microscopy, Confocal; Microscopy, Electron; Monocrotaline; Myocytes, Cardiac; Phosphoric Diester Hydrolases; Rats, Wistar; Receptors, Adrenergic, beta-1; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Thapsigargin | 2015 |
Therapeutic Approaches in Mitochondrial Dysfunction, Proteolysis, and Structural Alterations of Diaphragm and Gastrocnemius in Rats With Chronic Heart Failure.
Topics: Acetylcysteine; Animals; Bortezomib; Diaphragm; Heart Failure; Humans; Mitochondria; Monocrotaline; Muscle, Skeletal; NF-kappa B; Oxidative Stress; Proteolysis; Rats | 2016 |
Time course of ubiquitin-proteasome and macroautophagy-lysosome pathways in skeletal muscle in rats with heart failure.
Topics: Animals; Autophagy; Body Weight; Disease Models, Animal; Heart; Heart Failure; Lung; Lysosomes; Male; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Organ Size; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Ubiquitin | 2015 |
Endostatin is protective against monocrotaline-induced right heart disease through the inhibition of T-type Ca(2+) channel.
Topics: Animals; Blood Pressure; Calcium Channels, T-Type; Cell Line; Echocardiography; Endostatins; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Pulmonary Artery; Rats; Rats, Wistar; Systole | 2016 |
Fractal Dimension in Quantifying Experimental-Pulmonary-Hypertension-Induced Cardiac Dysfunction in Rats.
Topics: Animals; Disease Models, Animal; Echocardiography; Fractals; Heart Failure; Hypertension, Pulmonary; Male; Monocrotaline; Myocytes, Cardiac; Rats, Wistar; Reference Values; Reproducibility of Results; Stroke Volume; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right | 2016 |
Effects of TNF-alpha blockade in monocrotaline-induced pulmonary hypertension.
Topics: Animals; Etanercept; Heart Failure; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunoglobulin G; Male; Monocrotaline; Random Allocation; Rats; Rats, Wistar; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha | 2008 |
Opposite effects of training in rats with stable and progressive pulmonary hypertension.
Topics: Adaptation, Physiological; Animals; Biopsy; Capillaries; Cardiac Catheterization; Cardiac Output; Coronary Circulation; Disease Models, Animal; Disease Progression; Echocardiography; Heart Failure; Hypertension, Pulmonary; Male; Monocrotaline; Myocarditis; Physical Conditioning, Animal; Physical Endurance; Rats; Rats, Wistar; Rest; Survival Rate | 2009 |
Protective effects of hydroalcoholic extract from rhizomes of Cynodon dactylon (L.) Pers. on compensated right heart failure in rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cyanosis; Cynodon; Disease Models, Animal; Dyspnea; Fatigue; Heart; Heart Failure; Lung; Male; Monocrotaline; Myocardial Contraction; Phytotherapy; Plant Extracts; Random Allocation; Rats; Rats, Wistar; Rhizome | 2009 |
Pressure overload-induced right ventricular failure is associated with re-expression of myocardial tenascin-C and elevated plasma tenascin-C levels.
Topics: Animals; Blood Pressure; Gene Expression; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Immunohistochemistry; Integrins; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Rats; Rats, Wistar; Tenascin; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure; Ventricular Remodeling | 2009 |
Right ventricular pacing improves right heart function in experimental pulmonary arterial hypertension: a study in the isolated heart.
Topics: Animals; Cardiac Pacing, Artificial; Chronic Disease; Disease Models, Animal; Heart Failure; Heart Septum; Hypertension, Pulmonary; In Vitro Techniques; Magnetic Resonance Imaging; Male; Monocrotaline; Myocardial Contraction; Perfusion; Rats; Reproducibility of Results; Time Factors; Ventricular Dysfunction, Right; Ventricular Function, Left; Ventricular Function, Right; Ventricular Pressure | 2009 |
Possible involvement of mitochondrial energy-producing ability in the development of right ventricular failure in monocrotaline-induced pulmonary hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Cardiomyopathy, Dilated; Heart; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Male; Mitochondria, Heart; Monocrotaline; Myocardium; Organ Size; Oxygen Consumption; Phosphocreatine; Random Allocation; Rats; Rats, Wistar; Ultrasonography | 2009 |
Alterations in dystrophin-related glycoproteins in development of right ventricular failure in rats.
Topics: Animals; Calpain; Dystroglycans; Dystrophin-Associated Protein Complex; Heart Failure; Heart Ventricles; Hemodynamics; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Monocrotaline; Myocardium; Rats; Rats, Wistar; Sarcoglycans; Time Factors; Ventricular Dysfunction, Right | 2009 |
Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure.
Topics: Animals; Antioxidants; Disease Models, Animal; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Organometallic Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Salicylates; Ventricular Dysfunction, Right; Ventricular Remodeling | 2010 |
Heart failure increases atrogin-1 and MuRF1 gene expression in skeletal muscle with fiber type-specific atrophy.
Topics: Animals; Gene Expression Regulation; Heart Failure; Male; Monocrotaline; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; Organ Specificity; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2010 |
Early inflammatory response during the development of right ventricular heart failure in a rat model.
Topics: Animals; Autoradiography; Disease Models, Animal; Disease Progression; Gallium Radioisotopes; Gene Expression Profiling; Heart Failure; Hypertrophy, Right Ventricular; Immunochemistry; Inflammation; Male; Monocrotaline; Myocardium; Neutrophil Activation; Peroxidase; Radionuclide Imaging; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Right | 2010 |
Differential morphofunctional characteristics and gene expression in fast and slow muscle of rats with monocrotaline-induced heart failure.
Topics: Animals; Gene Expression Regulation; Heart Failure; Male; Monocrotaline; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscular Atrophy; MyoD Protein; Myogenin; Rats; Rats, Wistar; RNA, Messenger | 2011 |
Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Antihypertensive Agents; Bisoprolol; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Echocardiography; Fibrosis; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Male; Monocrotaline; Rats; Rats, Wistar; Signal Transduction; Vascular Resistance | 2012 |
Sildenafil prevents and reverses transverse-tubule remodeling and Ca(2+) handling dysfunction in right ventricle failure induced by pulmonary artery hypertension.
Topics: Animals; Calcium; Disease Models, Animal; Excitation Contraction Coupling; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Microscopy, Confocal; Monocrotaline; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Treatment Outcome; Ventricular Dysfunction, Right; Ventricular Remodeling | 2012 |
Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension.
Topics: Animals; Citrate (si)-Synthase; Gene Expression; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Male; Mitochondria, Muscle; Monocrotaline; Muscle, Skeletal; Nuclear Respiratory Factor 1; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Wistar; RNA-Binding Proteins; Sirtuin 1; Transcription Factors; Ventricular Dysfunction, Right | 2013 |
Effect of thalidomide on the skeletal muscle in experimental heart failure.
Topics: Animals; Apoptosis; Heart Failure; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Rats; Rats, Sprague-Dawley; Sphingosine; Thalidomide; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Right | 2002 |
L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Carnitine; Caspase 3; Caspase 9; Caspases; Cell Nucleus; Cells, Cultured; Cytoprotection; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Glucose Transporter Type 4; Heart Failure; In Situ Nick-End Labeling; Liver Function Tests; Male; Monocrotaline; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Muscular Disorders, Atrophic; Myosin Heavy Chains; Protein Isoforms; Rats; Rats, Sprague-Dawley; Sphingolipids; Staurosporine; Tumor Necrosis Factor-alpha | 2002 |
Myocardial force development and structural changes associated with monocrotaline induced cardiac hypertrophy and heart failure.
Topics: Animals; Cardiomegaly; Heart Failure; In Vitro Techniques; Male; Monocrotaline; Myocardial Contraction; Myocardium; Rats; Rats, Wistar | 2002 |
Ventricular hypertrophy plus neurohumoral activation is necessary to alter the cardiac beta-adrenoceptor system in experimental heart failure.
Topics: Animals; Binding, Competitive; Cell Membrane; Disease Models, Animal; Eye Proteins; Fluoxetine; G-Protein-Coupled Receptor Kinase 1; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Organ Size; Protein Kinases; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Rhodopsin; Symporters | 2002 |
Skeletal muscle abnormalities in rats with experimentally induced heart hypertrophy and failure.
Topics: Animals; Disease Models, Animal; Heart Failure; Hypertrophy, Right Ventricular; Monocrotaline; Muscle, Skeletal; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley | 2003 |
Effect of nolomirole on monocrotaline-induced heart failure.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Aldosterone; Animals; Ascitic Fluid; Atrial Natriuretic Factor; Body Weight; Disease Models, Animal; Dopamine Agonists; Drug Evaluation, Preclinical; Esters; Female; Heart Atria; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Indoles; Monocrotaline; Norepinephrine; Pleural Effusion; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes | 2004 |
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.
Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Dichloroacetic Acid; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kv1.5 Potassium Channel; Mitochondria; Monocrotaline; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Organ Specificity; Oxidative Phosphorylation; Potassium Channels, Voltage-Gated; Pulmonary Artery; Rats; Shab Potassium Channels; Vascular Resistance | 2004 |
Decreased vagal control over heart rate in rats with right-sided congestive heart failure: downregulation of neuronal nitric oxide synthase.
Topics: Acetylcholine; Animals; Atrial Function, Right; Down-Regulation; Heart Atria; Heart Failure; Heart Rate; In Vitro Techniques; Male; Monocrotaline; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Receptor, Muscarinic M2; Sinoatrial Node; Vagus Nerve | 2005 |
YM598, an orally active ET(A) receptor antagonist, ameliorates the progression of cardiopulmonary changes and both-side heart failure in rats with cor pulmonale and myocardial infarction.
Topics: Administration, Oral; Animals; Cardiovascular Agents; Coronary Vessels; Disease Models, Animal; Disease Progression; Endothelin A Receptor Antagonists; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Ligation; Male; Monocrotaline; Myocardial Infarction; Pulmonary Heart Disease; Pyrimidines; Rats; Rats, Wistar; Receptor, Endothelin A; Sulfonamides | 2004 |
Skeletal muscle myofibrillar protein oxidation in heart failure and the protective effect of Carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Bisoprolol; Carbazoles; Carvedilol; Heart Failure; Male; Monocrotaline; Muscle Proteins; Muscle, Skeletal; Myofibrils; Oxidation-Reduction; Propanolamines; Rats; Rats, Sprague-Dawley | 2005 |
Reduced inotropic effect of nifekalant in failing hearts in rats.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Cardiotonic Agents; Disease Models, Animal; Heart Failure; Monocrotaline; Myocardial Contraction; Pyrimidinones; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum | 2006 |
Myocyte morphological characteristics differ between the phases of pulmonary hypertension-induced ventricular hypertrophy and failure.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Disease Progression; Heart Failure; Hypertension, Pulmonary; Male; Monocrotaline; Muscle Cells; Myocardium; Prognosis; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Ventricular Pressure; Ventricular Remodeling | 2006 |
Sequence of echocardiographic changes during development of right ventricular failure in rat.
Topics: Animals; Disease Models, Animal; Disease Progression; Heart Failure; Male; Monocrotaline; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Ultrasonography; Ventricular Dysfunction, Right | 2006 |
Heart failure alters matrix metalloproteinase gene expression and activity in rat skeletal muscle.
Topics: Animals; Diaphragm; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Gene Expression; Heart Failure; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Monocrotaline; Muscle, Skeletal; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Cardiac sympathetic rejuvenation: a link between nerve function and cardiac hypertrophy.
Topics: Adrenergic Fibers; Animals; Dopamine; Endothelin-1; GAP-43 Protein; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Kinetics; Male; Monocrotaline; Myocytes, Cardiac; Nerve Growth Factor; Neural Cell Adhesion Molecule L1; Norepinephrine; Rats; Rats, Wistar; Sialic Acids; Tubulin; Tyrosine 3-Monooxygenase; Up-Regulation | 2007 |
Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension.
Topics: Animals; Cardiac Output; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Signal Transduction | 2007 |
Carnitine-mediated improved response to erythropoietin involves induction of haem oxygenase-1: studies in humans and in an animal model.
Topics: Animals; Apoptosis; Carnitine; Disease Models, Animal; Erythropoiesis; Erythropoietin; Heart Failure; Hematocrit; Heme Oxygenase-1; Hemoglobins; Humans; Leukocytes, Mononuclear; Male; Monocrotaline; Muscle, Skeletal; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Renal Dialysis; Signal Transduction | 2008 |
Contrasting effects of isoproterenol and phosphodiesterase III inhibitor on intracellular calcium transients in cardiac myocytes from failing hearts.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcium; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 3; Fura-2; Heart; Heart Failure; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Rats; Rats, Sprague-Dawley | 1994 |
Calcium transients in single myocytes and membranous ultrastructures during the development of cardiac hypertrophy and heart failure in rats.
Topics: Animals; Calcium; Cell Membrane; Heart Failure; Hypertrophy, Right Ventricular; Isometric Contraction; Isoproterenol; Male; Microscopy, Electron, Scanning; Mitochondria, Heart; Monocrotaline; Myocardial Contraction; Myocardium; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum | 1994 |
Activation of ANP synthesis during congestive heart failure in rats treated with monocrotaline.
Topics: Animals; Ascitic Fluid; Atrial Natriuretic Factor; Cardiomegaly; Female; Gene Expression; Heart Failure; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Organ Specificity; Pleural Effusion; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1995 |
Right heart failure chronically stimulates heat shock protein 72 in heart and liver but not in other tissues.
Topics: Animals; Autoradiography; Blotting, Western; Female; Heart Failure; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Hypertrophy, Right Ventricular; Liver; Lung; Monocrotaline; Muscle, Skeletal; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley | 1996 |
Aorta and skeletal muscle NO synthase expression in experimental heart failure.
Topics: Animals; Aorta; Ascites; Body Weight; Endothelium, Vascular; Female; Heart Failure; Monocrotaline; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organ Size; Pleural Effusion; Rats; Rats, Sprague-Dawley | 1996 |
Skeletal muscle metabolism in experimental heart failure.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Disease Models, Animal; Female; Heart Failure; Monocrotaline; Muscle, Skeletal; NAD; Organ Size; Oxidation-Reduction; Phosphocreatine; Rats; Rats, Sprague-Dawley | 1996 |
Heat shock protein changes in hibernation: a similarity with heart failure?
Topics: Animals; Female; Heart Failure; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; In Vitro Techniques; Monocrotaline; Myocardial Stunning; Rats; Rats, Sprague-Dawley | 1996 |
Apoptosis and atrophy in rat slow skeletal muscles in chronic heart failure.
Topics: Animals; Apoptosis; Atrophy; Blotting, Western; Body Weight; Caspase 3; Caspases; Cell Nucleus; Chronic Disease; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Male; Monocrotaline; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Ubiquitins | 1999 |
Enhanced expression and activity of xanthine oxidoreductase in the failing heart.
Topics: Animals; Coronary Vessels; Disease Models, Animal; Disease Progression; Enzyme Induction; Female; Free Radicals; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Ligation; Monocrotaline; Muscle Proteins; Myocardial Infarction; Organ Size; Rats; Rats, Sprague-Dawley; Xanthine Oxidase | 2000 |
Chamber-specific alterations of noradrenaline uptake (uptake(1)) in right ventricles of monocrotaline-treated rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Heart Failure; Heart Ventricles; Hypertrophy; In Vitro Techniques; Male; Membranes; Monocrotaline; Norepinephrine; Piperazines; Rats; Rats, Wistar; Tritium | 2000 |
Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Biphenyl Compounds; Calcium Channel Blockers; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infusion Pumps, Implantable; Irbesartan; Male; Monocrotaline; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Nifedipine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha | 2001 |
Attenuation of compensatory right ventricular hypertrophy and heart failure following monocrotaline-induced pulmonary vascular injury by the Na+-H+ exchange inhibitor cariporide.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Natriuretic Factor; Cell Size; Enzyme Inhibitors; Guanidines; Heart Failure; Hemodynamics; Hypertrophy, Right Ventricular; Lung; Lung Diseases; Male; Monocrotaline; Myocardium; Organ Size; Poisons; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Hydrogen Exchangers; Sulfones | 2001 |
Changes in ventricular 1,2-diacylglycerol content in rats following monocrotaline treatment.
Topics: Animals; Cardiomegaly; Diglycerides; DNA; Fatty Acids; Heart Failure; Heart Ventricles; Hypertension, Pulmonary; Lipid Metabolism; Male; Monocrotaline; Myocardium; Osmolar Concentration; Rats; Rats, Wistar; RNA | 1992 |
Changes in contractile and non-contractile proteins, intracellular Ca2+ and ultrastructures during the development of right ventricular hypertrophy and failure in rats.
Topics: Animals; Calcium; Cardiomegaly; Collagen; Heart Failure; Hypertension, Pulmonary; Male; Microscopy, Electron, Scanning; Mitochondria, Heart; Monocrotaline; Myocardial Contraction; Myocardium; Myosins; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1992 |
Biventricular down-regulation of beta-adrenergic receptors in right ventricular hypertrophy induced by monocrotaline.
Topics: Animals; Cardiomegaly; Down-Regulation; Epinephrine; Heart Failure; Heart Ventricles; Male; Monocrotaline; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1991 |
Altered myocardial acetylcholine and norepinephrine concentrations in right ventricular hypertrophy and failure.
Topics: Acetylcholine; Animals; Cardiomegaly; Heart; Heart Failure; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains | 1991 |
Beneficial effects of trimetazidine on mitochondrial function and superoxide production in the cardiac muscle.
Topics: Animals; Heart Failure; Male; Mitochondria, Heart; Monocrotaline; Plants, Toxic; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Superoxides; Trimetazidine | 1990 |
Effect of congestive heart failure on rate of atrial natriuretic factor release in response to stretch and isoprenaline.
Topics: Animals; Atrial Natriuretic Factor; Heart Atria; Heart Failure; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Myocardial Contraction; Myocardium; Norepinephrine; Organ Size; Plants, Toxic; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Time Factors | 1990 |
Noradrenaline, atrial natriuretic peptide, bombesin and neurotensin in myocardium and blood of rats in congestive cardiac failure.
Topics: Animals; Atrial Natriuretic Factor; Bombesin; Cardiomegaly; Heart Atria; Heart Failure; Heart Ventricles; Monocrotaline; Myocardium; Neurotensin; Norepinephrine; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1989 |
Isoproterenol sensitivity of isolated cardiac myocytes from rats with monocrotaline-induced right-sided hypertrophy and heart failure.
Topics: Animals; Calcium-Transporting ATPases; Cardiomegaly; Catecholamines; Cells, Cultured; Disease Models, Animal; Drug Tolerance; Heart; Heart Failure; Heart Ventricles; Isoproterenol; Male; Monocrotaline; Myocardial Contraction; Myocardium; Myosins; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1989 |