monocrotaline and Body Weight

Topics: Animals; Body Weight; Cardiotonic Agents; Collagen Type IV; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Fibrosis; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Kidney; Lung; Male; Monocrotaline; Organ Size; Peptide Fragments; Rats; Rats, Wistar; Recombinant Proteins; Ventricular Remodeling

Topics: Aminobutyrates; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Body Weight; Disease Models, Animal; Disease Progression; Drug Combinations; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Rats; Rats, Sprague-Dawley; Tetrazoles; Valsartan

Topics: Animals; Atrophy; Body Weight; Diaphragm; Disease Models, Animal; Eating; Hypertension, Pulmonary; Male; Mice; Mice, Inbred C57BL; Monocrotaline; Muscle Contraction

Topics: Animals; Blood Pressure; Body Weight; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Endothelin-1; Guanylate Cyclase; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Nitric Oxide Synthase Type III; Piperazines; Piperidines; Pulmonary Artery; Purines; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Sildenafil Citrate; Soluble Guanylyl Cyclase; Sulfonamides; Vasoconstriction; Xanthines

Topics: Administration, Oral; Age Factors; Animals; Body Weight; Bone Marrow; Carcinogens; Chromosome Aberrations; Cooperative Behavior; Dose-Response Relationship, Drug; Drug Administration Schedule; Hepatocytes; Humans; Japan; Leukocytes, Mononuclear; Liver; Male; Micronucleus Tests; Monocrotaline; Organ Specificity; Rats; Rats, Sprague-Dawley; Reticulocytes; Societies, Pharmaceutical

Topics: Animals; Autophagy; Body Weight; Disease Models, Animal; Heart; Heart Failure; Lung; Lysosomes; Male; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Organ Size; Proteasome Endopeptidase Complex; Rats; Rats, Wistar; Ubiquitin

Topics: Animals; Benzhydryl Compounds; Body Weight; Cyclic AMP; Disease Models, Animal; Endothelin-1; Gene Expression Regulation; Heart Ventricles; Humans; Hypertension, Pulmonary; Intermediate-Conductance Calcium-Activated Potassium Channels; Male; Modafinil; Monocrotaline; Myocytes, Smooth Muscle; Pressure; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Vasoconstriction

Topics: Acetylcholine; Animals; Atorvastatin; Blotting, Western; Body Weight; Caspase 3; Celecoxib; Cyclooxygenase Inhibitors; Disease Progression; Drug Combinations; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrazoles; Pyrroles; Rats; Rats, Wistar; Sulfonamides; Survival Analysis; Vasodilator Agents

Topics: Animals; Anorexia; Blotting, Western; Body Weight; Cachexia; Eating; Enzyme-Linked Immunosorbent Assay; Gene Expression; Heart Diseases; Male; Monocrotaline; Muscle, Skeletal; Organ Size; Pentoxifylline; Poisons; Rats; Rats, Sprague-Dawley; Receptors, Tumor Necrosis Factor, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tumor Necrosis Factor Inhibitors; Ubiquitin; Weight Loss

Topics: Animals; Blood Gas Analysis; Body Weight; Disease Progression; Fibroblast Growth Factor 2; Gelatin; Hemodynamics; Hydrogels; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Microspheres; Monocrotaline; Rats; Rats, Wistar; Trachea

Topics: Animals; Blood Pressure; Body Weight; Endothelin-1; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Monocrotaline; Organ Size; Ovariectomy; Pulmonary Artery; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Substrate Specificity; Time Factors; Ventricular Dysfunction, Right

Topics: Administration, Oral; Animal Structures; Animals; Antibodies; Antibody Formation; Body Weight; Bone Marrow; Bone Marrow Cells; Cell Count; Eating; Hydrogen Peroxide; Hypersensitivity, Delayed; Immunity, Cellular; Immunity, Innate; L-Lactate Dehydrogenase; Lipopolysaccharides; Macrophages, Peritoneal; Male; Monocrotaline; Nitric Oxide; Phagocytosis; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

Topics: Animals; Body Weight; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Myocardial Contraction; Organ Size; Perfusion; Rats; Rats, Wistar; Ventricular Function, Right

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Body Weight; Echocardiography; Fibrosis; Histocytochemistry; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Monocrotaline; Myocardium; Organ Size; Rats; Rats, Wistar; Stroke Volume; Systole; Telmisartan; Transforming Growth Factor beta1; Ventricular Remodeling

Topics: Animals; Antioxidants; Beverages; Body Weight; Disease Models, Animal; Lipid Peroxidation; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Organ Size; Pulmonary Heart Disease; Rats; Rats, Wistar; Ventricular Pressure; Vitis

Topics: Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; HSP90 Heat-Shock Proteins; Hypertension, Pulmonary; Immunoprecipitation; Kaplan-Meier Estimate; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Artery; Rats; Rats, Sprague-Dawley

Topics: Animals; Aspirin; Blood Pressure; Body Weight; Disease Models, Animal; Heart Rate; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Platelet Aggregation; Platelet Aggregation Inhibitors; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Serotonin; Survival Analysis

Topics: Animals; Automation; Azo Compounds; Body Weight; Electrocardiography; Fibrosis; Hemodynamics; Humans; Hypertension, Pulmonary; Image Processing, Computer-Assisted; Microscopy, Polarization; Monocrotaline; Myocardium; Organ Size; Paraffin Embedding; Rats; Rats, Wistar; Time Factors; Ultrasonography

Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Body Weight; Fluorobenzenes; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Organ Size; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Signal Transduction; Sulfonamides; Ventricular Dysfunction, Right

Topics: 4-Aminobenzoic Acid; Animals; Body Weight; Cardiomegaly; Disease Models, Animal; Endothelin-1; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; para-Aminobenzoates; Pulmonary Artery; Rats; Rats, Wistar; Survival Analysis

Topics: Animals; Blotting, Western; Body Weight; Diestrus; Estradiol; Female; Glutathione; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Ovariectomy; Oxidative Stress; Plant Oils; Pulmonary Artery; Rats; Rats, Wistar; Sunflower Oil

Topics: Animals; Antioxidants; Atmosphere Exposure Chambers; Blood Pressure; Body Weight; Capsaicin; Female; Heart Rate; Humans; Hypertension, Pulmonary; Hypoxia; Male; Monocrotaline; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Reactive Oxygen Species; Sensory System Agents; Substance P

Topics: Animals; Aspartic Acid Endopeptidases; Body Weight; Endothelin-Converting Enzymes; Heart Ventricles; Hypertension, Pulmonary; Lentivirus; Lung; Male; Metalloendopeptidases; Monocrotaline; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; RNA, Small Interfering; Survival Rate; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

Topics: Animals; Body Weight; Cardiomegaly; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypertension, Pulmonary; Inflammation; Lung; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Monocrotaline; Myocytes, Cardiac; Rats; Stress, Mechanical; Ventricular Function, Right

Topics: Animals; Appetite Depressants; Body Weight; Dexfenfluramine; Eating; Endothelium, Vascular; Female; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Nitric Oxide Synthase; Obesity; Organ Size; Pancreatic Elastase; Pulmonary Artery; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Vascular Diseases

Topics: Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Disease Models, Animal; Gene Expression Regulation; Heart Ventricles; Hemodynamics; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Lung; Male; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organ Size; Pneumonectomy; Pulmonary Artery; Rats; Rats, Sprague-Dawley; RNA, Messenger; Simvastatin; Treatment Outcome; Tunica Intima

Topics: Animals; Blood Pressure; Body Weight; Heart Rate; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Organ Size; Rats; Rats, Wistar; Receptors, Tachykinin; RNA Interference; RNA, Double-Stranded; Substance P; Tachykinins

Topics: Angiogenesis Inducing Agents; Angiopoietin-1; Angiopoietin-2; Animals; Apoptosis; Body Weight; Caspase 3; Caspases; Cell Transplantation; Cells, Cultured; Cytoprotection; Genetic Therapy; Hypertension, Pulmonary; Lung; Membrane Glycoproteins; Monocrotaline; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; RNA, Messenger; Transfection; Transgenes; Ventricular Pressure

Topics: Actin Cytoskeleton; Adrenergic beta-Agonists; Animals; Biomechanical Phenomena; Body Weight; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Isoproterenol; Male; Monocrotaline; Myocardial Contraction; Norepinephrine; Organ Size; Rats; Rats, Wistar; RNA, Messenger; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stress, Mechanical

Topics: Angiotensin II; Animals; Apoptosis; Body Weight; Cardiac Output, Low; Caspases; Cytochromes c; Human Growth Hormone; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Isometric Contraction; Male; Monocrotaline; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Physical Endurance; Rats; Rats, Sprague-Dawley; Sphingosine; Tumor Necrosis Factor-alpha

Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Body Weight; Densitometry; Disease Progression; Enalapril; Endothelin-1; Estrogens; Female; Hypertrophy, Right Ventricular; Male; Microscopy, Electron; Monocrotaline; Ovariectomy; Rats; Rats, Sprague-Dawley; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sex Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling

Topics: Administration, Oral; Adrenergic alpha-Agonists; Aldosterone; Animals; Ascitic Fluid; Atrial Natriuretic Factor; Body Weight; Disease Models, Animal; Dopamine Agonists; Drug Evaluation, Preclinical; Esters; Female; Heart Atria; Heart Failure; Heart Ventricles; Hypertrophy, Right Ventricular; Indoles; Monocrotaline; Norepinephrine; Pleural Effusion; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes

Topics: Animals; Blood Pressure; Body Weight; Calcium; Dioxoles; Endothelins; Female; Hypertrophy, Right Ventricular; Monocrotaline; Myocardial Contraction; Organ Size; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum

Topics: Administration, Oral; Animals; Atrasentan; Blood Pressure; Body Mass Index; Body Weight; Cardiomegaly; Drug Administration Schedule; Drug Therapy, Combination; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Injections, Subcutaneous; Intubation, Gastrointestinal; Lung; Male; Monocrotaline; Organ Size; Pulmonary Artery; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Time Factors; Tunica Media; Ventricular Pressure

Topics: Animals; Body Weight; Diet; Dose-Response Relationship, Drug; Female; Larva; Male; Molecular Structure; Monocrotaline; Morphogenesis; Moths; Pheromones; Pyrrolizidine Alkaloids; Sexual Behavior, Animal; Social Behavior

Topics: 2-Methoxyestradiol; Animals; Blood Pressure; Body Weight; Cell Proliferation; Disease Progression; Estradiol; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Lung; Male; Monocrotaline; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Time Factors; Tubulin Modulators

Topics: Acetylcholine; Animals; Apoptosis; Blood Pressure; Blotting, Western; Body Weight; Caspase 3; Disease Progression; Endothelial Cells; Heart Function Tests; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Nitroprusside; Poisons; Pravastatin; Pulmonary Artery; Rats; Rats, Wistar; Survival; Vasodilator Agents

Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Coronary Disease; Endothelium, Vascular; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Nitric Oxide; Organ Size; Poisons; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Sulfonamides

Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Olmesartan Medoxomil; Pulmonary Artery; Rats; Rats, Wistar; Tetrazoles; Time Factors

Topics: Animals; Blood Pressure; Body Weight; Cilostazol; Connexin 43; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Hypertension, Pulmonary; Male; Monocrotaline; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasodilator Agents

Topics: Animals; Blood Cell Count; Body Weight; Cardiomegaly; Electrocardiography; Heart; Heart Ventricles; Hypertension, Pulmonary; Kinetics; Lung; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

Topics: Animals; Body Weight; Cardiomegaly; Dexamethasone; Heart Diseases; Hydralazine; L-Lactate Dehydrogenase; Lung; Lung Diseases; Monocrotaline; Myocardium; Organ Size; Pyrrolizidine Alkaloids; Rats; Sulfinpyrazone

Topics: Animals; Body Weight; Endothelium; Epoprostenol; Lung; Lung Injury; Male; Microscopy, Electron; Monocrotaline; Organ Size; Peptidyl-Dipeptidase A; Plasminogen Activators; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

Topics: Amino Acids; Animal Feed; Animals; Anisoles; Body Weight; Butylated Hydroxyanisole; Cysteine; Folic Acid; Food, Fortified; Male; Monocrotaline; Plant Poisoning; Plants, Toxic; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Rodent Diseases; Senecio; Vitamin B 12; Vitamin B Complex

Topics: Aflatoxin B1; Aflatoxins; Animals; Blood Proteins; Body Weight; Carcinogens; Kidney; Liver; Male; Monocrotaline; Pyrrolizidine Alkaloids; Turkeys

Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Platelet Disorders; Body Weight; Cardiomegaly; Dose-Response Relationship, Drug; Lung; Male; Monocrotaline; Perfusion; Plants, Toxic; Platelet Count; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio

Topics: Age Factors; Animals; Body Weight; Injections, Intraperitoneal; Liver; Lung; Monocrotaline; Neoplasms, Experimental; Pyrrolizidine Alkaloids; Rats; Thioacetamide

Topics: Animals; Blood Platelets; Body Weight; Hypertension, Pulmonary; Immune Sera; Lung; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Thrombocytosis

Topics: Altitude; Animals; Animals, Newborn; Arterioles; Body Weight; Female; Heart Ventricles; Hypoxia; Lung; Male; Microscopy, Electron; Monocrotaline; Organ Size; Rats; Rats, Wistar; Vasoconstrictor Agents

Topics: Animals; Blood Pressure; Body Weight; Capsaicin; Cardiomegaly; Endopeptidases; Hypertension, Pulmonary; Monocrotaline; Nerve Fibers; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Respiratory Function Tests; Respiratory Tract Diseases; Substance P

Topics: Animals; Behavior, Animal; Body Weight; Drug Implants; Estradiol; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Organ Size; Pulmonary Artery; Pulmonary Circulation; Pulmonary Edema; Rats; Rats, Sprague-Dawley

Topics: Animals; Body Weight; DNA; Energy Intake; Heart Ventricles; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Organ Size; Ornithine Decarboxylase; Polyamines; Rats; Rats, Sprague-Dawley

Topics: Acute Disease; Animals; Body Weight; Disease Models, Animal; Drug Evaluation, Preclinical; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy; Injections, Intraperitoneal; Monocrotaline; Nifedipine; Organ Size; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley

Topics: Animals; Body Weight; Cysteine; Glutathione; Lung; Male; Monocrotaline; Pulmonary Heart Disease; Rats; Rats, Sprague-Dawley

Topics: Amino Acids; Animals; Body Weight; Cysteine; Glutathione; Liver; Male; Monocrotaline; Organ Size; Rats; Rats, Sprague-Dawley; Taurine

Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart; Hypertension, Pulmonary; Male; Monocrotaline; Rats; Rats, Wistar; Thiazoles

Topics: Amrinone; Animals; Body Weight; Bronchi; Cardiotonic Agents; Fibroblast Growth Factor 2; Hypertension, Pulmonary; Immunohistochemistry; Lung; Male; Monocrotaline; Myocardium; Organ Size; Phosphodiesterase Inhibitors; Platelet-Derived Growth Factor; Poisons; Rats; Rats, Sprague-Dawley; Vasodilator Agents

Topics: Animals; Aorta; Ascites; Body Weight; Endothelium, Vascular; Female; Heart Failure; Monocrotaline; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Organ Size; Pleural Effusion; Rats; Rats, Sprague-Dawley

Topics: Animals; Body Weight; Disease Models, Animal; Dogs; Hemodynamics; Hypertension, Pulmonary; Monocrotaline; Myocardial Contraction; Nitric Oxide; Pulmonary Circulation; Regional Blood Flow; Vascular Resistance

Topics: Animals; Body Weight; Disease Models, Animal; Heart; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardial Contraction; Poisons; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Stimulation, Chemical; Vasoconstriction

Topics: Animals; Body Weight; Cardiomyopathy, Dilated; Electrophoresis, Polyacrylamide Gel; Monocrotaline; Muscle, Skeletal; Myosin Heavy Chains; Rats; Rats, Sprague-Dawley; Regional Blood Flow

Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Atrial Natriuretic Factor; Body Weight; Calcium Signaling; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Hypertension, Pulmonary; Ligands; Male; Monocrotaline; Nitric Oxide; Nitriles; Organ Size; Phosphodiesterase Inhibitors; Piperidines; Rats; Rats, Wistar; Survival Rate

Topics: Acetylcholine; Adrenomedullin; Animals; Aorta, Thoracic; Body Weight; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Male; Monocrotaline; Organ Size; Peptides; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Vasodilation; Vasodilator Agents

Topics: Animals; Body Weight; Calcium; Carbachol; Cyclic GMP; Endothelium, Vascular; Hypertension, Pulmonary; In Vitro Techniques; Male; Monocrotaline; Muscarinic Agonists; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organ Size; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

Topics: Animals; Apoptosis; Atrophy; Blotting, Western; Body Weight; Caspase 3; Caspases; Cell Nucleus; Chronic Disease; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Situ Nick-End Labeling; Male; Monocrotaline; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Ubiquitins

Topics: Adenylyl Cyclases; Animals; Blood Pressure; Blotting, Western; Body Weight; Cardiomegaly; Disease Models, Animal; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Kinetics; Male; Monocrotaline; Myocardium; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Muscarinic; Time Factors

Topics: Animals; Body Weight; Carbon; Free Radical Scavengers; Hematocrit; Hypertension, Pulmonary; Immunoenzyme Techniques; Luminescent Measurements; Male; Monocrotaline; Muscle, Smooth, Vascular; Poisons; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Reactive Oxygen Species; Substance P; Thiourea

Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Creatinine; Cysteine; Eating; Female; Fetal Death; Fetus; Male; Monocrotaline; Organ Size; Plant Extracts; Poisoning; Pregnancy; Rats; Rats, Wistar; Treatment Failure; Urea

Topics: Angiotensin II; Animals; Biphenyl Compounds; Body Weight; Hypertension, Pulmonary; Imidazoles; Losartan; Male; Monocrotaline; Pressoreceptors; Rats; Rats, Inbred Strains; Renin; Tetrazoles

Topics: Animals; Blood Coagulation; Body Weight; Bronchoalveolar Lavage Fluid; Cardiomegaly; Injections, Intravenous; Lung; Male; Monocrotaline; Organ Size; Partial Thromboplastin Time; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

Topics: Animals; Body Weight; Bronchoalveolar Lavage Fluid; L-Lactate Dehydrogenase; Lung; Male; Monocrotaline; Organ Size; Proteins; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors

Topics: Animals; Antibodies; Body Weight; Dose-Response Relationship, Drug; Erythrocytes; Female; Immunization; Immunocompetence; Leukocyte Count; Liver; Lung; Mice; Mice, Inbred Strains; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Random Allocation; Spleen; Viral Plaque Assay

Topics: Animals; Biomarkers; Body Weight; Bronchoalveolar Lavage Fluid; Dimethylformamide; Hemodynamics; Hypertension, Pulmonary; Injections, Intravenous; L-Lactate Dehydrogenase; Lung; Male; Monocrotaline; Organ Size; Proteins; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Time Factors

Topics: Angiotensin I; Angiotensin II; Animals; Autacoids; Blood Pressure; Body Weight; Bradykinin; Dinoprostone; Injections, Subcutaneous; Lung; Lung Diseases; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Substance P; Time Factors

Topics: Animals; Biogenic Polyamines; Body Weight; Eflornithine; Heart; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

Topics: Animals; Blood Platelets; Body Weight; Dimethylformamide; Hemoglobins; Hypertension, Pulmonary; Indium Radioisotopes; Injections, Intravenous; Lung; Male; Monocrotaline; Platelet Count; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Splenectomy

Topics: Animals; Biotransformation; Body Weight; Cardiomegaly; Diet; Diet, Sodium-Restricted; L-Lactate Dehydrogenase; Lung Diseases; Male; Monocrotaline; Organ Size; Proteins; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Sodium

Topics: Animals; Body Weight; Captopril; Hydroxyproline; Lung; Male; Monocrotaline; Organ Size; Penicillamine; Peptidyl-Dipeptidase A; Plants, Toxic; Proline; Pulmonary Fibrosis; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Occlusive Diseases; Body Weight; Heart; Hydroxyproline; Hypertension; Lung; Male; Monocrotaline; Organ Size; Peptidyl-Dipeptidase A; Plasminogen Activators; Proline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Cardiomegaly; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Organ Size; Peptidyl-Dipeptidase A; Pyrrolizidine Alkaloids; Rats; Sulfhydryl Compounds

Topics: Animals; Body Weight; Butylated Hydroxyanisole; Chickens; Chlorohydrins; Ethylene Chlorohydrin; Female; Liver; Male; Monocrotaline; Organ Size; Pyrroles; Pyrrolizidine Alkaloids

Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Body Weight; Hydrostatic Pressure; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Organ Size; Perfusion; Pyrrolizidine Alkaloids; Rats; Thromboxane B2; Time Factors

Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Male; Monocrotaline; Norepinephrine; Organ Size; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Serotonin; Vasoconstriction

Topics: Animals; Blood Pressure; Body Weight; Carbon Dioxide; Endothelium, Vascular; Heart Ventricles; Hematocrit; Hypertension, Pulmonary; Male; Monocrotaline; Organ Size; Oxygen; Partial Pressure; Plants, Toxic; Pulmonary Artery; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Senecio; Vascular Resistance

Topics: Animals; Body Weight; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Male; Methylprednisolone; Monocrotaline; Pulmonary Heart Disease; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains

Topics: Animals; Antilymphocyte Serum; Body Weight; Bronchoalveolar Lavage Fluid; Cyclosporins; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy; Immunization, Passive; Immunosuppressive Agents; L-Lactate Dehydrogenase; Lung; Lymphocytes; Male; Monocrotaline; Organ Size; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Inbred Strains