Page last updated: 2024-08-18

monobutyl phthalate and Pregnancy

monobutyl phthalate has been researched along with Pregnancy in 36 studies

*Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. [MeSH]

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (8.33)18.2507
2000's15 (41.67)29.6817
2010's10 (27.78)24.3611
2020's8 (22.22)2.80

Authors

AuthorsStudies
Fragki, S; Hoogenveen, R; Piersma, AH; Schwillens, P; van Oostrom, C; Zeilmaker, MJ1
Liu, YJ; Shen, XB; Tian, YK; Wang, LL; Wang, X; Xiong, SM; Zhang, HN; Zhou, YZ1
Lin, YC; Lin, ZN; Qian, B; Wang, CQ; Yang, L; Zheng, ZX1
Bommarito, PA; Boyer, TM; Cantonwine, DE; Ferguson, KK; James-Todd, T; McElrath, TF; Meeker, JD; Welch, BM1
Fernando, RA; Robinson, VG; Silinski, MAR; Waidyanatha, S1
Ding, J; Han, X; Ji, J; Li, D; Ma, T; Wang, Y; Wu, J; Xia, Y; Zhang, L1
Hlisníková, H; Kolena, B; Mlynček, M; Petrovičová, I; Šidlovská, M1
Ding, J; Han, X; Jin, H; Li, D; Ma, T; Wang, B; Wang, J; Wu, J; Xia, Y; Yang, F; Zhou, Y1
Chuang, CJ; Huang, HB; Su, PH; Sun, CW; Wang, CJ; Wang, SL; Wu, MT1
Brock, JW; Cruze, L; Kucklick, JR; Newman, RB; Somerville, SE; Unal, ER; Wenzel, AG; Wolf, BJ1
Chang, JW; Chiang, HC; Huang, HB; Huang, PC; Kuo, PL; Liao, KW1
Balmes, J; Berger, K; Calafat, AM; Eskenazi, B; Harley, KG; Holland, N1
Li, X; Liu, L; Shen, H; Wang, H; Xiao, T; Zhang, X1
Chen, X; Leng, L; Ma, J; Sun, Z; Tang, N; Yu, H; Zhou, Q1
Fan, Z; Gao, F; Hu, J; Mu, D; Peng, H; Shen, H1
Bonde, JP; Hjollund, NH; Jensen, TK; Jönsson, BA; Lindh, CH; Olsen, J; Riis, AH; Thomsen, AM; Toft, G1
Andersen, ME; Borghoff, SJ; Campbell, JL; Clewell, RA; Kremer, JJ; Sochaski, MA; Williams, CC1
Calafat, AM; Hauser, R; Hernández-Díaz, S; Kelley, KE; Mitchell, AA1
Kelnar, CJ; McKinnell, C; Mitchell, RT; Morris, K; Sharpe, RM; Walker, M; Wallace, WH1
Dorman, DC; Gaido, KW; Hensley, JB; Lehmann, KP; Ross, SM; Sochaski, MA; Struve, MF; Willson, GA1
Hines, M; Kruse, RL; Liu, F; Redmon, JB; Sparks, A; Swan, SH; Wang, C; Weiss, B1
Ballester, F; Calafat, AM; Casas, L; Fernández, MF; Guxens, M; Irurzun, MB; Llop, S; Olea, N; Riaño, I; Rodríguez, LS; Sunyer, J; Tardón, A; Vrijheid, M1
Ema, M1
Gaido, KW; Ross, SM; Thompson, CJ1
Kai, H; Shono, T; Suita, S; Tajiri, T1
Borghoff, SJ; Kremer, JJ; Parkinson, HD; Williams, CC1
Barr, DB; Brock, JW; Calafat, AM; Gray, LE; Needham, LL; Reidy, JA; Silva, MJ1
Kondo, T; Shima, Y; Shono, T; Suita, S1
Anderson, RA; Bayne, R; Coutts, S; Greig, I; Hallmark, N; Mahood, IK; McKinnell, C; Morris, K; Scott, H; Sharpe, RM; Walker, M1
Guo, YL; Huang, PC; Kuo, PL; Lee, CC; Liao, PC1
Andersen, ME; Borghoff, SJ; Campbell, JL; Clewell, RA; Kremer, JJ; Williams, CC1
Amano, H; Ema, M; Kurosaka, R; Ogawa, Y1
Amano, H; Ema, M; Harazono, A; Kurosaka, R; Ogawa, Y1
Imajima, T; Shono, T; Suita, S; Zakaria, O1
Imajima, T; Kai, H; Shono, T; Suita, S; Zakaria, O1
Langonné, I; Leheup, B; Saillenfait, AM1

Reviews

2 review(s) available for monobutyl phthalate and Pregnancy

ArticleYear
Association between exposures to phthalate metabolites and preterm birth and spontaneous preterm birth: A systematic review and meta-analysis.
    Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 113

    Topics: Environmental Exposure; Environmental Pollutants; Female; Humans; Infant, Newborn; Phthalic Acids; Pregnancy; Premature Birth; Prospective Studies

2022
Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats.
    Congenital anomalies, 2002, Volume: 42, Issue:4

    Topics: Androgen Antagonists; Animals; Dibutyl Phthalate; Female; Phthalic Acids; Pregnancy; Rats; Rats, Wistar

2002

Other Studies

34 other study(ies) available for monobutyl phthalate and Pregnancy

ArticleYear
Integrating in vitro chemical transplacental passage into a generic PBK model: A QIVIVE approach.
    Toxicology, 2022, 01-15, Volume: 465

    Topics: Animals; Biological Transport; Biomarkers; Caproates; Cell Line; Dose-Response Relationship, Drug; Female; Fetal Blood; Gestational Age; Glycolates; Humans; Maternal-Fetal Exchange; Miconazole; Models, Biological; Permeability; Phthalic Acids; Pregnancy; Proof of Concept Study; Rats; Reproducibility of Results; Risk Assessment; Silanes; Toxicity Tests; Toxicokinetics; Triazoles; Trophoblasts; Valproic Acid

2022
Prenatal exposure to phthalates and polybrominated diphenyl ethers on neonatal health: A birth cohort study in Guangxi, China.
    Environmental research, 2023, 01-01, Volume: 216, Issue:Pt 2

    Topics: Birth Cohort; China; Cohort Studies; Female; Halogenated Diphenyl Ethers; Humans; Infant Health; Infant, Newborn; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects

2023
Maternal exposure to phthalates and total gestational weight gain in the LIFECODES birth cohort.
    Reproductive toxicology (Elmsford, N.Y.), 2023, Volume: 117

    Topics: Birth Cohort; Birth Weight; Case-Control Studies; Environmental Pollutants; Female; Gestational Weight Gain; Humans; Infant, Newborn; Maternal Exposure; Obesity; Phthalic Acids; Pregnancy; Prospective Studies; Weight Gain

2023
Development and Validation of an Analytical Method for Quantitation of Monobutylphthalate, a Metabolite of Di-n-Butylphthalate, in Rat Plasma, Amniotic Fluid, Fetuses and Pups by UPLC-MS/MS.
    Journal of analytical toxicology, 2020, May-18, Volume: 44, Issue:4

    Topics: Amniotic Fluid; Animals; Calibration; Chromatography, Liquid; Dibutyl Phthalate; Female; Lactation; Limit of Detection; Phthalic Acids; Plasma; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry

2020
In utero exposure to DBP stimulates release of GnRH by increasing the secretion of PGE2 in the astrocytes of the hypothalamus in the offspring mice.
    Ecotoxicology and environmental safety, 2020, Jul-15, Volume: 198

    Topics: Animals; Astrocytes; Bodily Secretions; Dibutyl Phthalate; Dinoprostone; Endocrine Disruptors; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Male; Mice; Neurons; Phthalic Acids; Pregnancy; Reproduction

2020
Effect of prenatal phthalate exposure on the association of maternal hormone levels during early pregnancy and reproductive markers in infants at the age of 3 months.
    Reproductive toxicology (Elmsford, N.Y.), 2021, Volume: 102

    Topics: Adult; Cohort Studies; Endocrine Disruptors; Environmental Pollutants; Female; Humans; Infant; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction; Tandem Mass Spectrometry; Testosterone

2021
Environmentally relevant perinatal exposure to DBP disturbs testicular development and puberty onset in male mice.
    Toxicology, 2021, Volume: 459

    Topics: Animals; Blood-Testis Barrier; Dibutyl Phthalate; Endocrine Disruptors; Female; Gonadal Steroid Hormones; Leydig Cells; Male; Maternal Exposure; Mice; Mice, Inbred BALB C; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Sexual Maturation; Spermatogenesis; Steroids; Testis

2021
Prenatal and Childhood Exposure to Phthalate Diesters and Thyroid Function in a 9-Year Follow-up Birth Cohort Study: Taiwan Maternal and Infant Cohort Study.
    Epidemiology (Cambridge, Mass.), 2017, Volume: 28 Suppl 1

    Topics: Adult; Child; Child, Preschool; Cohort Studies; Diethylhexyl Phthalate; Environmental Exposure; Female; Humans; Infant; Infant, Newborn; Male; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Taiwan; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine; Young Adult

2017
Prevalence and predictors of phthalate exposure in pregnant women in Charleston, SC.
    Chemosphere, 2018, Volume: 193

    Topics: Adult; Biomarkers; Cross-Sectional Studies; Endocrine Disruptors; Environmental Exposure; Female; Humans; Phthalic Acids; Plasticizers; Pregnancy; Prevalence; Socioeconomic Factors; South Carolina; Young Adult

2018
Increased risk of phthalates exposure for recurrent pregnancy loss in reproductive-aged women.
    Environmental pollution (Barking, Essex : 1987), 2018, Volume: 241

    Topics: Adult; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans; Phthalic Acids; Pregnancy; Pregnancy Outcome; Reproduction; Risk; Taiwan

2018
Associations between prenatal maternal urinary concentrations of personal care product chemical biomarkers and childhood respiratory and allergic outcomes in the CHAMACOS study.
    Environment international, 2018, Volume: 121, Issue:Pt 1

    Topics: Adolescent; Adult; Asthma; Bayes Theorem; Biomarkers; Child; Cohort Studies; Cosmetics; Eczema; Environmental Exposure; Female; Humans; Hypersensitivity; Longitudinal Studies; Male; Maternal Exposure; Parabens; Phenols; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Young Adult

2018
Phthalate exposure and cumulative risk in a Chinese newborn population.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:8

    Topics: Adult; Asian People; Child; China; Cross-Sectional Studies; Dibutyl Phthalate; Environmental Exposure; Environmental Pollutants; Female; Humans; Infant, Newborn; No-Observed-Adverse-Effect Level; Phthalic Acids; Pregnancy; Public Health; Retrospective Studies; Risk Assessment; Tandem Mass Spectrometry

2019
[Study on the association between maternal urinary phthalate metabolites and testicular steroid hormones in the cord blood in a Chinese population].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2014, Volume: 48, Issue:3

    Topics: Adult; Diethylhexyl Phthalate; Female; Fetal Blood; Humans; Infant, Newborn; Inhibin-beta Subunits; Insulin; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Proteins; Testicular Hormones; Young Adult

2014
Levels of Phthalate Metabolites in Urine of Pregnant Women and Risk of Clinical Pregnancy Loss.
    Environmental science & technology, 2015, Sep-01, Volume: 49, Issue:17

    Topics: Adult; Beijing; Case-Control Studies; Embryo Loss; Environmental Monitoring; Esters; Female; Humans; Metabolome; Middle Aged; Odds Ratio; Phthalic Acids; Pregnancy; Risk Factors; Young Adult

2015
Female exposure to phthalates and time to pregnancy: a first pregnancy planner study.
    Human reproduction (Oxford, England), 2017, Volume: 32, Issue:1

    Topics: Adult; Environmental Exposure; Female; Fertility; Humans; Phthalic Acids; Pregnancy; Time-to-Pregnancy; Young Adult

2017
Kinetics of selected di-n-butyl phthalate metabolites and fetal testosterone following repeated and single administration in pregnant rats.
    Toxicology, 2009, Jan-08, Volume: 255, Issue:1-2

    Topics: Amniotic Fluid; Animals; Area Under Curve; Biomarkers; Calibration; Chromatography, High Pressure Liquid; Dibutyl Phthalate; Dose-Response Relationship, Drug; Female; Fetus; Gas Chromatography-Mass Spectrometry; Indicators and Reagents; Liver; Male; Mass Spectrometry; Phthalic Acids; Placenta; Pregnancy; Quality Control; Quinolines; Rats; Rats, Sprague-Dawley; Sexual Maturation; Testis; Testosterone

2009
Medications as a potential source of exposure to phthalates in the U.S. population.
    Environmental health perspectives, 2009, Volume: 117, Issue:2

    Topics: Adolescent; Adult; Data Collection; Didanosine; Environmental Exposure; Female; Humans; Male; Mesalamine; Middle Aged; Omeprazole; Pharmaceutical Preparations; Phthalic Acids; Pregnancy; Theophylline; Young Adult

2009
Effect of fetal or neonatal exposure to monobutyl phthalate (MBP) on testicular development and function in the marmoset.
    Human reproduction (Oxford, England), 2009, Volume: 24, Issue:9

    Topics: Animals; Animals, Newborn; Callithrix; Female; Germ Cells; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Sertoli Cells; Testis

2009
Reproductive toxicity and pharmacokinetics of di-n-butyl phthalate (DBP) following dietary exposure of pregnant rats.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2009, Volume: 86, Issue:4

    Topics: Administration, Oral; Amniotic Fluid; Androgen Antagonists; Animals; Biotransformation; Body Weight; Dibutyl Phthalate; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Developmental; Genitalia, Male; Gestational Age; Glucuronides; Male; Phthalic Acids; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Scavenger Receptors, Class B; Steroids; Testis; Testosterone

2009
Prenatal phthalate exposure and reduced masculine play in boys.
    International journal of andrology, 2010, Volume: 33, Issue:2

    Topics: Child, Preschool; Dibutyl Phthalate; Diethylhexyl Phthalate; Environmental Exposure; Female; Gender Identity; Humans; Infant; Male; Maternal Exposure; Phthalic Acids; Play and Playthings; Pregnancy; Prenatal Exposure Delayed Effects; Sex Differentiation

2010
Urinary concentrations of phthalates and phenols in a population of Spanish pregnant women and children.
    Environment international, 2011, Volume: 37, Issue:5

    Topics: Adult; Benzhydryl Compounds; Child, Preschool; Chlorophenols; Cohort Studies; Environmental Exposure; Environmental Pollutants; Female; Humans; Male; Phenols; Phthalic Acids; Pregnancy; Pregnancy Trimester, Third; Pregnant Women; Spain

2011
Di(n-butyl) phthalate impairs cholesterol transport and steroidogenesis in the fetal rat testis through a rapid and reversible mechanism.
    Endocrinology, 2004, Volume: 145, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Dibutyl Phthalate; DNA-Binding Proteins; Female; Fushi Tarazu Transcription Factors; Gene Expression; Homeodomain Proteins; Male; Phthalic Acids; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Steroidogenic Factor 1; Testis; Testosterone; Transcription Factors; Transcription, Genetic

2004
Long-term effects of intrauterine exposure to mono-n-butyl phthalate on the reproductive function of postnatal rats.
    Journal of pediatric surgery, 2005, Volume: 40, Issue:2

    Topics: Animals; Anti-Mullerian Hormone; Female; Glycoproteins; Immunohistochemistry; Infertility, Male; Leydig Cells; Male; Phthalic Acids; Plasticizers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; RNA, Messenger; Sertoli Cells; Testicular Hormones; Testis; Testosterone

2005
Pharmacokinetics of monobutylphthalate, the active metabolite of di-n-butylphthalate, in pregnant rats.
    Toxicology letters, 2005, Nov-15, Volume: 159, Issue:2

    Topics: Animals; Chromatography, Liquid; Dibutyl Phthalate; Female; Fetus; Glucuronides; Male; Mass Spectrometry; Maternal-Fetal Exchange; Phthalic Acids; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Teratogens

2005
Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalate.
    Toxicology, 2006, Jan-05, Volume: 217, Issue:1

    Topics: Administration, Oral; Amniotic Fluid; Animals; Creatinine; Dibutyl Phthalate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Female; Gestational Age; Glucuronides; Male; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley

2006
In utero exposure to mono-n-butyl phthalate impairs insulin-like factor 3 gene expression and the transabdominal phase of testicular descent in fetal rats.
    Journal of pediatric surgery, 2005, Volume: 40, Issue:12

    Topics: Animals; Cryptorchidism; Female; Gene Expression Regulation; Insulin; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Testis

2005
Effects of monobutyl and di(n-butyl) phthalate in vitro on steroidogenesis and Leydig cell aggregation in fetal testis explants from the rat: comparison with effects in vivo in the fetal rat and neonatal marmoset and in vitro in the human.
    Environmental health perspectives, 2007, Volume: 115, Issue:3

    Topics: Animals; Animals, Newborn; Callithrix; Cell Aggregation; Dibutyl Phthalate; Female; Humans; Leydig Cells; Male; Maternal Exposure; Phthalic Acids; Pregnancy; Rats; Rats, Wistar; Testis; Testosterone

2007
Associations between urinary phthalate monoesters and thyroid hormones in pregnant women.
    Human reproduction (Oxford, England), 2007, Volume: 22, Issue:10

    Topics: Adult; Creatinine; Diethylhexyl Phthalate; Environmental Exposure; Estradiol; Female; Humans; Longitudinal Studies; Phthalic Acids; Pregnancy; Regression Analysis; Thyroid Hormones; Thyroxine; Triiodothyronine

2007
Tissue exposures to free and glucuronidated monobutylyphthalate in the pregnant and fetal rat following exposure to di-n-butylphthalate: evaluation with a PBPK model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 103, Issue:2

    Topics: Administration, Oral; Animals; Area Under Curve; Dibutyl Phthalate; Female; Fetus; Glucuronides; Male; Maternal Exposure; Models, Biological; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley; Tissue Distribution

2008
Developmental toxicity evaluation of mono-n-butyl phthalate in rats.
    Toxicology letters, 1995, Volume: 78, Issue:2

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Body Weight; Embryonic and Fetal Development; Female; Fetal Resorption; Male; Maternal-Fetal Exchange; Phthalic Acids; Pregnancy; Rats; Rats, Wistar; Teratogens

1995
Phase specificity of developmental toxicity after oral administration of mono-n-butyl phthalate in rats.
    Archives of environmental contamination and toxicology, 1996, Volume: 31, Issue:2

    Topics: Administration, Oral; Animals; Cervical Vertebrae; Cleft Palate; Embryonic and Fetal Development; Female; Gestational Age; Male; Maternal-Fetal Exchange; Phthalic Acids; Pregnancy; Rats; Rats, Wistar

1996
Prenatal phthalate causes cryptorchidism postnatally by inducing transabdominal ascent of the testis in fetal rats.
    Journal of pediatric surgery, 1997, Volume: 32, Issue:1

    Topics: Abdomen; Age Factors; Animals; Anti-Mullerian Hormone; Cryptorchidism; Female; Gestational Age; Glycoproteins; Growth Inhibitors; Male; Mullerian Ducts; Phthalic Acids; Plasticizers; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred Strains; Rats, Wistar; Sertoli Cells; Testicular Hormones; Testis; Urinary Bladder

1997
The biological effect of phthalate esters on transabdominal migration of the testis in fetal rats in comparison with the antiandrogen flutamide.
    Pediatric surgery international, 2001, Volume: 17, Issue:2-3

    Topics: Animals; Cryptorchidism; Female; Flutamide; Gestational Age; Humans; Infant, Newborn; Male; Phthalic Acids; Pregnancy; Rats; Rats, Wistar; Testis

2001
Effects of mono-n-butyl phthalate on the development of rat embryos: in vivo and in vitro observations.
    Pharmacology & toxicology, 2001, Volume: 89, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Dibutyl Phthalate; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; Female; Organ Culture Techniques; Phthalic Acids; Pregnancy; Rats; Rats, Sprague-Dawley

2001