monensin and Cytomegalovirus-Infections

monensin has been researched along with Cytomegalovirus-Infections* in 1 studies

Reviews

1 review(s) available for monensin and Cytomegalovirus-Infections

ArticleYear
Analyzing T-cell responses to cytomegalovirus by cytokine flow cytometry.
    Human immunology, 2004, Volume: 65, Issue:5

    T-cell responses to human cytomegalovirus (CMV) are readily detected in chronically infected adults, and are thought to be important for protection from CMV-related pathology. Antigen-specific cytokine flow cytometry (CFC) has been used to establish the range of CMV-specific CD4 and CD8 T-cell frequencies in healthy CMV-seropositive (and seronegative) adults, as well as the dynamics of these cells over time. There are also emerging data regarding the primary CD4 and CD8 T-cell response to CMV in children and adults. Finally, CFC has been used to analyze CMV responses in chronic human immunodeficiency virus infection, as well as during immune reconstitution after bone marrow or stem cell transplantation. These data will be reviewed in terms of what they suggest about the threshold of protective T-cell immunity to CMV, and other factors in addition to T-cell frequencies that could be important in protecting from CMV-associated disease.

    Topics: Aging; Antibodies; Antigens; Brefeldin A; CD28 Antigens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Flow Cytometry; Humans; Immunocompromised Host; Integrin alpha4; Interferon-gamma; Interleukin-2; Interleukin-4; Leukocytes, Mononuclear; Monensin; Peptide Fragments; Phosphoproteins; T-Lymphocytes; Tumor Necrosis Factor-alpha; Viral Matrix Proteins

2004