monensin and Anemia

monensin has been researched along with Anemia* in 2 studies

Other Studies

2 other study(ies) available for monensin and Anemia

Article	Year
Hematological changes in case of chronic cadmium intoxication and monensin detoxication. Relationship with rheological variables. Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4 The study evaluated the affect of chronic cadmium (Cd) and monensin treatment on some hematological parameters and its relationship with the rheological variables. Adult male mice were subjected to chronic treatment with cadmium acetate [Cd(CH3COO)2 × 2H2O] (group 1), Cd(CH3COO)2 × 2H2O followed by treatment with low dose monensin (group 2) and Cd(CH3COO)2 × 2H2O followed by high dose monensin treatment (group 3). Cd(CH3COO)2 × 2H2O and deprotonated monensin were dissolved in distilled water and given daily to the experimental animals. Mice drinking distilled water served as a control group (group 4). Hematological parameters and erythrocyte morphology were evaluated in parallel with whole blood viscosity (WBV). Cd treatment reduced Hb and increased RDW. The addition of high dose monensin significantly improved erythrocytic indices compared to the control. Erythrocyte anisocytosis was observed in blood smears of Cd-treated mice corresponding to the increased RDW. WBV was significantly elevated in the experimental groups in the whole range of shear rates compared to the control group and in groups 2 and 3 was lower than in group 1 but remained higher compared to group 4. Correlations were found between WBV and RBC, Hb, Hct, MCV and RDW. The results suggest that hemorheological parameters such as WBV should be monitored in parallel with the hematological parameters when monensin is applied and heavy metal intoxication is suspected. Topics: Acetates; Anemia; Animals; Antidotes; Blood Viscosity; Cadmium; Chronic Disease; Environmental Pollutants; Erythrocyte Indices; Erythrocytes; Erythrocytes, Abnormal; Hemoglobins; Hemorheology; Ionophores; Male; Mice; Mice, Inbred BALB C; Monensin	2011
Outbreaks of proliferative haemorrhagic enteropathy on two pig farms. Australian veterinary journal, 1995, Volume: 72, Issue:7 Clinical signs of proliferative haemorrhagic enteropathy (PHE) including anaemia, dysentery and sudden death were observed in finisher pigs and young breeding stock on 2 farms. On farm A, PHE occurred 12 months after repopulation of the farm. Other outbreaks of PHE occurred after the withdrawal of therapeutic concentrations of in-feed antibacterial agents (farm A), or after monensin sodium (100 g/t) replaced olaquindox (100 g/t) in feed (farm B). The outbreaks, the possible sources of contamination and the role of antibacterial feed additives in the treatment and control of PHE are described. Topics: Anemia; Animal Feed; Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Bacterial Infections; Disease Outbreaks; Drug Therapy, Combination; Dysentery; Enteritis; Epithelium; Female; Gastrointestinal Hemorrhage; Intestine, Large; Intestine, Small; Male; Monensin; Pregnancy; Quinoxalines; Swine; Swine Diseases; Victoria	1995

Article

Year

Hematological changes in case of chronic cadmium intoxication and monensin detoxication. Relationship with rheological variables.

Clinical hemorheology and microcirculation, 2011, Volume: 49, Issue:1-4

The study evaluated the affect of chronic cadmium (Cd) and monensin treatment on some hematological parameters and its relationship with the rheological variables. Adult male mice were subjected to chronic treatment with cadmium acetate [Cd(CH3COO)2 × 2H2O] (group 1), Cd(CH3COO)2 × 2H2O followed by treatment with low dose monensin (group 2) and Cd(CH3COO)2 × 2H2O followed by high dose monensin treatment (group 3). Cd(CH3COO)2 × 2H2O and deprotonated monensin were dissolved in distilled water and given daily to the experimental animals. Mice drinking distilled water served as a control group (group 4). Hematological parameters and erythrocyte morphology were evaluated in parallel with whole blood viscosity (WBV). Cd treatment reduced Hb and increased RDW. The addition of high dose monensin significantly improved erythrocytic indices compared to the control. Erythrocyte anisocytosis was observed in blood smears of Cd-treated mice corresponding to the increased RDW. WBV was significantly elevated in the experimental groups in the whole range of shear rates compared to the control group and in groups 2 and 3 was lower than in group 1 but remained higher compared to group 4. Correlations were found between WBV and RBC, Hb, Hct, MCV and RDW. The results suggest that hemorheological parameters such as WBV should be monitored in parallel with the hematological parameters when monensin is applied and heavy metal intoxication is suspected.

Topics: Acetates; Anemia; Animals; Antidotes; Blood Viscosity; Cadmium; Chronic Disease; Environmental Pollutants; Erythrocyte Indices; Erythrocytes; Erythrocytes, Abnormal; Hemoglobins; Hemorheology; Ionophores; Male; Mice; Mice, Inbred BALB C; Monensin

2011

Outbreaks of proliferative haemorrhagic enteropathy on two pig farms.

Australian veterinary journal, 1995, Volume: 72, Issue:7

Clinical signs of proliferative haemorrhagic enteropathy (PHE) including anaemia, dysentery and sudden death were observed in finisher pigs and young breeding stock on 2 farms. On farm A, PHE occurred 12 months after repopulation of the farm. Other outbreaks of PHE occurred after the withdrawal of therapeutic concentrations of in-feed antibacterial agents (farm A), or after monensin sodium (100 g/t) replaced olaquindox (100 g/t) in feed (farm B). The outbreaks, the possible sources of contamination and the role of antibacterial feed additives in the treatment and control of PHE are described.

Topics: Anemia; Animal Feed; Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Bacterial Infections; Disease Outbreaks; Drug Therapy, Combination; Dysentery; Enteritis; Epithelium; Female; Gastrointestinal Hemorrhage; Intestine, Large; Intestine, Small; Male; Monensin; Pregnancy; Quinoxalines; Swine; Swine Diseases; Victoria

1995