monascin has been researched along with Liver-Diseases--Alcoholic* in 2 studies
2 other study(ies) available for monascin and Liver-Diseases--Alcoholic
| Article | Year |
|---|---|
Monascin and Ankaflavin of
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antioxidants; Central Nervous System Depressants; Ethanol; Flavins; Heterocyclic Compounds, 3-Ring; Lipid Metabolism; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Monascus | 2021 |
Monascus-fermented red mold dioscorea protects mice against alcohol-induced liver injury, whereas its metabolites ankaflavin and monascin regulate ethanol-induced peroxisome proliferator-activated receptor-γ and sterol regulatory element-binding transcrip
Alcoholic hepatitis is a necroinflammatory process that is associated with fibrosis and leads to cirrhosis in 40% of cases. The hepatoprotective effects of red mold dioscorea (RMD) from Monascus purpureus NTU 568 were evaluated in vivo using a mouse model of chronic alcohol-induced liver disease (ALD).. ALD mice were orally administered vehicle (ALD group) or vehicle plus 307.5, 615.0 or 1537.5 mg kg. These results indicate the hepatoprotective effect of Monascus-fermented RMD. Moreover, AK and MS were identified as the active constituents of RMD for the first time and were shown to protect against ethanol-induced liver damage. © 2017 Society of Chemical Industry. Topics: Animals; Dioscorea; Ethanol; Fermentation; Flavins; Hep G2 Cells; Heterocyclic Compounds, 3-Ring; Humans; Liver Diseases, Alcoholic; Male; Mice; Mice, Inbred C57BL; Monascus; Plant Tubers; PPAR gamma; Protective Agents; Sterol Regulatory Element Binding Protein 1 | 2018 |