monascin and Carcinoma--Ehrlich-Tumor

monascin has been researched along with Carcinoma--Ehrlich-Tumor* in 1 studies

Other Studies

1 other study(ies) available for monascin and Carcinoma--Ehrlich-Tumor

Article	Year
Phytosomal bilayer-enveloped casein micelles for codelivery of monascus yellow pigments and resveratrol to breast cancer. Nanomedicine (London, England), 2018, Volume: 13, Issue:5 Multireservoir nanocarriers were fabricated for delivering antineoplastic drug cocktail from herbal and fungal origin. Monascus yellow pigments (MYPs), monascin and ankaflavin, were isolated from red-mold rice, and incorporated within casein micelles (CAS MCs) along with the herbal drug, resveratrol (RSV). Both drugs (MYPs and RSV) were simultaneously incorporated into the hydrophobic core of CAS MCs. Alternatively, MYPs-loaded CAS MCs were enveloped within RSV-phytosomal bilayer elaborating multireservoir nanocarriers.. Cytotoxicity studies confirmed the superiority of multireservoir nanocarriers against MCF-7 breast cancer cells. The in vivo antitumor efficacy was revealed by reduction of the tumor volume and growth biomarkers.. Multireservoir CAS nanocarriers for codelivery of both MYPs and RSV may be promising alternative to traditional breast cancer therapy. Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Caseins; Cell Survival; Drug Carriers; Drug Therapy, Combination; Female; Flavins; Heterocyclic Compounds, 3-Ring; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Mice, Inbred BALB C; Micelles; Monascus; Nanoparticles; Particle Size; Rats; Resveratrol	2018

Article

Year

Phytosomal bilayer-enveloped casein micelles for codelivery of monascus yellow pigments and resveratrol to breast cancer.

Nanomedicine (London, England), 2018, Volume: 13, Issue:5

Multireservoir nanocarriers were fabricated for delivering antineoplastic drug cocktail from herbal and fungal origin. Monascus yellow pigments (MYPs), monascin and ankaflavin, were isolated from red-mold rice, and incorporated within casein micelles (CAS MCs) along with the herbal drug, resveratrol (RSV). Both drugs (MYPs and RSV) were simultaneously incorporated into the hydrophobic core of CAS MCs. Alternatively, MYPs-loaded CAS MCs were enveloped within RSV-phytosomal bilayer elaborating multireservoir nanocarriers.. Cytotoxicity studies confirmed the superiority of multireservoir nanocarriers against MCF-7 breast cancer cells. The in vivo antitumor efficacy was revealed by reduction of the tumor volume and growth biomarkers.. Multireservoir CAS nanocarriers for codelivery of both MYPs and RSV may be promising alternative to traditional breast cancer therapy.

Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Caseins; Cell Survival; Drug Carriers; Drug Therapy, Combination; Female; Flavins; Heterocyclic Compounds, 3-Ring; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Mice, Inbred BALB C; Micelles; Monascus; Nanoparticles; Particle Size; Rats; Resveratrol

2018