mometasone-furoate has been researched along with Snoring* in 3 studies
2 trial(s) available for mometasone-furoate and Snoring
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The role of mometasone furoate nasal spray in the treatment of adenoidal hypertrophy in the adolescents: a prospective, randomized, cross-over study.
Aim of this work is to find out whether the symptoms attributable to adenoid hypertrophy in adolescents may be treated with intranasal mometasone furoate (MF) application. To learn if adenoid hypertrophy in adolescents may decrease in size with intranasal MF. A prospective, double blind, randomized, cross-over study was conducted in 28 subjects (12-18 years) with adenoidal hypertrophy. Subjects used intranasal MF or placebo for a duration of 6 weeks with a wash out period of 3 weeks. Subjective symptoms and adenoid size were evaluated. At the initiation of the study, there was no significant difference between the mean symptom scores for any of the sinonasal symptoms between the two treatment groups. There was significant improvement in total subjective symptoms (nasal blockage, rhinorrhea, cough, snoring and disruption of quality of life scores) with MF compared with placebo. Analysis of the symptoms separately showed a significant positive effect of MF on all symptoms except for rhinorrhea. Nasal endoscopic evaluation failed to demonstrate any difference in the reduction of the adenoid size between the two groups. MF has significant advantage over placebo for the symptoms attributable to adenoid hypertrophy in adolescents. Topics: Adenoids; Adolescent; Anti-Inflammatory Agents; Child; Cough; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertrophy; Male; Mometasone Furoate; Nasal Obstruction; Nasal Sprays; Organ Size; Pregnadienediols; Prospective Studies; Snoring; Treatment Outcome | 2013 |
To treat snoring with nasal steroids - effects on more than one level?
An inflammatory swelling in the uvula and nose due to vibration might be a contributing factor in snoring. The presence of corticosteroid receptors in the uvula indicates the possibility for treatment with local steroids. Use of mometasone furoate (MF) for 3 months reduced snoring and related symptoms in some patients.. To investigate the effect of a nasal steroid, MF, on snoring and related discomfort.. In the first part of the study, uvular and nasal biopsies from six patients with social snoring were examined using immunohistochemistry to evaluate whether corticosteroid receptors were present. Then 100 snoring patients were invited to participate in the second part of the study. In all, 72 men and 22 women with a mean age of 47 years and BMI 27 answered a questionnaire about symptoms, had ENT status assessed and reported sleep and related variables for a 7 day period. After randomization to placebo or MF, they used a nasal spray for 3 months at a dosage of 200 microg. Thereafter the procedure was repeated.. Corticosteroid receptors were present in the mucous membranes and around the blood vessels in all uvulas examined. A total of 84 patients were evaluated. No decrease in 'mean snoring score' was seen. Daytime sleepiness showed a slight improvement in the MF group and partners were less disturbed. Minor side effects were equal for both groups. Topics: Administration, Intranasal; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Biopsy; Female; Humans; Male; Middle Aged; Mometasone Furoate; Nasal Mucosa; Pregnadienediols; Receptors, Steroid; Snoring; Uvula; Young Adult | 2010 |
1 other study(ies) available for mometasone-furoate and Snoring
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[Chronic sinusitis, polyps, snoring. Topical glucocorticosteroid can relieve symptoms].
Topics: Administration, Topical; Anti-Inflammatory Agents; Chronic Disease; Glucocorticoids; Humans; Mometasone Furoate; Nasal Polyps; Nose Neoplasms; Pregnadienediols; Sinusitis; Snoring | 2001 |