mometasone-furoate and Scalp-Dermatoses

Erosive pustular dermatosis of the scalp has particular relevance in Australia, due to its association with actinic damage. Despite its rarity, the recalcitrant nature of erosive pustular dermatosis of the scalp dictates a protracted recovery fraught with relapse and recurrence, posing inherent challenges to successful treatment and complete recovery. In Australia, erosive pustular dermatosis of the scalp is prevalent in the elderly, who are negatively affected due to the condition. We propose a management outline to aid clinical practice, to improve the quality of life in the elderly, whilst providing insight into the current understanding and treatment of erosive pustular dermatosis of the scalp.

Topics: Algorithms; Anti-Inflammatory Agents; Australia; Betamethasone; Calcineurin Inhibitors; Curettage; Dermoscopy; Diagnosis, Differential; Glucocorticoids; Humans; Incidence; Mometasone Furoate; Recurrence; Scalp Dermatoses; Skin Diseases, Vesiculobullous; Tacrolimus

Topics: Administration, Topical; Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Administration Schedule; Glucocorticoids; Humans; Mometasone Furoate; Ointments; Pregnadienediols; Psoriasis; Random Allocation; Scalp Dermatoses; Triamcinolone Acetonide

Erosive pustular dermatosis of the scalp (EPDS) is a rare inflammatory condition commonly associated with antecedent iatrogenic insult. EPDS may be diagnostically challenging owing to a lack of pathognomonic histologic findings and cutaneous manifestations that overlap with alternative dermatologic conditions. Therefore, EPDS may be more common than previously recognized. We present a 60-year-old woman with a four-year history of non-healing scalp erosions, progressive skin atrophy, and scarring alopecia despite intravenous antibiotics and intraoperative debridement who improved with systemic glucocorticoids. Our report emphasizes the importance of early recognition of EPDS when delayed wound healing and erosive disease occur in the setting of iatrogenic injury to the scalp. Timely treatment with systemic anti-inflammatory agents is paramount to prevent cicatricial alopecia and mitigate further scalp insult in EPDS.

Topics: Alopecia; Anti-Inflammatory Agents; Female; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Mometasone Furoate; Osteomyelitis; Prednisone; Radiosurgery; Scalp; Scalp Dermatoses; Skin Diseases, Vesiculobullous

To evaluate patients' assessment of therapy, efficacy, quality of life and treatment adherence in patients with scalp psoriasis treated with non-alcoholic mometasone emulsion or calcipotriol/betamethasone gel.. Prospective, open-label, multicentre, non-interventional study. Patients with non-severe scalp psoriasis were treated with mometasone emulsion or calcipotriol/betamethasone gel. Evaluations included patient's global assessment of treatment, physician's global assessment of disease severity, quality of life (Dermatology Life Quality Index), physician's subjective evaluation of therapy, treatment adherence and adverse events.. Ninety-five patients treated with mometasone emulsion and 88 treated with calcipotriol/betamethasone gel were included in the intention-to-treat analysis. Patients' global assessment of treatment favoured mometasone emulsion over calcipotriol/betamethasone gel (p = 0.008), with treatment rated as good/very good by 91% versus 82.5%. Patients were less likely to report irritation of fingers' skin with mometasone than with calcipotriol/betamethasone (p = 0.0015). Severity of scalp psoriasis and quality of life improved in both groups. Adherence to treatment was similar in both groups. Physicians' perception of efficacy, tolerability and compliance was better for mometasone emulsion.. Non-alcoholic mometasone emulsion achieved greater acceptability to patients and physicians than calcipotriol/betamethasone gel for the treatment of scalp psoriasis. Both topical treatments were similarly effective in terms of disease severity and quality of life.

Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betamethasone; Calcitriol; Dermatologic Agents; Drug Combinations; Emulsions; Female; Glucocorticoids; Humans; Male; Middle Aged; Mometasone Furoate; Patient Acceptance of Health Care; Patient Compliance; Patient Preference; Prospective Studies; Psoriasis; Quality of Life; Scalp Dermatoses

Topics: Alopecia; Anti-Inflammatory Agents; Humans; Male; Middle Aged; Mometasone Furoate; Pregnadienediols; Scalp Dermatoses; Skin Cream

Both alopecia areata and vitiligo are common skin disorders that are considered to be caused by an autoimmune response targeted to hair follicle and melanocyte antigens, respectively. The association of these two diseases in the same patient is well known, however, coexistence of alopecia areata and vitiligo within the same lesion is very rare. Herein, we report an 8-year-old boy who had colocalization of alopecia areata and vitiligo on the frontal portion of his scalp.

Topics: Alopecia Areata; Anti-Inflammatory Agents; Child; Humans; Male; Mometasone Furoate; Pregnadienediols; Scalp Dermatoses; Vitiligo

Erosive pustular dermatosis of the scalp is a rare condition that tends to occur mainly in elderly patients. Clinically it is characterized by the presence of pustules, chronic crusted erosions with progressive scarring alopecia, and skin atrophy. Although etiology remains unclear, it seems to be triggered by local trauma such as surgical procedures, skin graft, ultraviolet light exposure, cryotherapy, craniotomy, or radiotherapy. To our knowledge, erosive pustular dermatosis of the scalp after photodynamic therapy has been seldom reported. We described a 81-year-old woman presenting with erosive pustular dermatosis of the scalp after photodynamic therapy for actinic keratosis.

Topics: Aged, 80 and over; Female; Humans; Keratosis, Actinic; Mometasone Furoate; Photochemotherapy; Pregnadienediols; Scalp Dermatoses; Skin Diseases, Vesiculobullous; Tacrolimus; Treatment Outcome