mometasone-furoate and Histiocytosis--Langerhans-Cell

We report a rare case of a 14-year-old boy with Langerhans cell histiocytosis localized to the prepuce. The patient was treated with a topical corticosteroid followed by imiquimod cream resulting in significant clinical improvement of the lesion. Although spontaneous remission is possible, the use of imiquimod may be an effective alternative therapy in cases of cutaneous Langerhans cell histiocytosis refractory to topical corticosteroids.

Topics: Adolescent; Histiocytosis, Langerhans-Cell; Humans; Imiquimod; Male; Mometasone Furoate; Remission, Spontaneous; Skin Neoplasms

Topics: Administration, Cutaneous; Antigens, CD; Biomarkers; Biopsy; Blister; Dermatologic Agents; Histiocytosis, Langerhans-Cell; Humans; Immunohistochemistry; Infant; Lectins, C-Type; Male; Mannose-Binding Lectins; Mometasone Furoate; Remission Induction; Skin; Treatment Outcome