mometasone-furoate and Alopecia

Erosive pustular dermatosis of the scalp (EPDS) is a rare inflammatory condition commonly associated with antecedent iatrogenic insult. EPDS may be diagnostically challenging owing to a lack of pathognomonic histologic findings and cutaneous manifestations that overlap with alternative dermatologic conditions. Therefore, EPDS may be more common than previously recognized. We present a 60-year-old woman with a four-year history of non-healing scalp erosions, progressive skin atrophy, and scarring alopecia despite intravenous antibiotics and intraoperative debridement who improved with systemic glucocorticoids. Our report emphasizes the importance of early recognition of EPDS when delayed wound healing and erosive disease occur in the setting of iatrogenic injury to the scalp. Timely treatment with systemic anti-inflammatory agents is paramount to prevent cicatricial alopecia and mitigate further scalp insult in EPDS.

Topics: Alopecia; Anti-Inflammatory Agents; Female; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Mometasone Furoate; Osteomyelitis; Prednisone; Radiosurgery; Scalp; Scalp Dermatoses; Skin Diseases, Vesiculobullous

Topics: Alopecia; Anti-Inflammatory Agents; Humans; Male; Middle Aged; Mometasone Furoate; Pregnadienediols; Scalp Dermatoses; Skin Cream

Topics: Alopecia; Child; Dermatologic Agents; Humans; Hyperplasia; Hypohidrosis; India; Male; Mometasone Furoate; Pregnadienediols; PUVA Therapy; Skin

Hair loss (alopecia) is a relatively common problem in childhood and the underlying pathophysiology and manifestations are diverse. We report four cases of hair loss with unusual distributions and discuss the outcome of their management. One child had alopecia with unilateral loss of hair over the eyebrow. He received topical corticosteroids and tacrolimus and his condition resolved. A girl had scalp alopecia which evolved to alopecia universalis. The mother and the child were non-compliant with treatment. A boy had alopecia totalis not responsive to Western or alternative treatment. The fourth child had trichotillomania and bizarre loss of scalp hair. Mother and child received psychological counselling and the child's hair loss improved. It is important to differentiate between alopecia and trichotillomania as the management is very different. Diagnosis and treatment are based on clinical assessment, evaluation of coexisting psychosocial factors and exclusion of autoimmune and other underlying disorders. In alopecia totalis or universalis, alternative therapy is often sought and tried for prolonged periods but efficacy has remained unproven. These cases serve to illustrate the principles of management of children with unusual patterns of hair loss.

Topics: Adolescent; Alopecia; Child, Preschool; Counseling; Diagnosis, Differential; Female; Glucocorticoids; Humans; Male; Mometasone Furoate; Pregnadienediols; Trichotillomania

Topics: Alopecia; Anti-Inflammatory Agents; Humans; Liver Transplantation; Living Donors; Massage; Mometasone Furoate; Postoperative Complications; Pregnadienediols; Pressure; Scalp; Supine Position