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molsidomine and Ventricular Fibrillation

molsidomine has been researched along with Ventricular Fibrillation in 2 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"The effect of the novel antianginal agent molsidomine on the incidence of spontaneous ventricular fibrillation during myocardial ischemia and reperfusion was investigated in the anesthetized dog."7.66Effect of molsidomine on spontaneous ventricular fibrillation following myocardial ischemia and reperfusion in the dog. ( Kettenbach, B; Martorana, PA; Mogilev, AM; Nitz, RE, 1983)
"The cardioprotective and antithrombotic activity of molsidomine, a novel therapeutic agent for the treatment of coronary heart disease, was investigated in a series of animal models of myocardial ischemia."4.77The activity of molsidomine in experimental models of ischemic cardiac disease. ( Martorana, PA; Nitz, RE, 1985)
"The effect of the novel antianginal agent molsidomine on the incidence of spontaneous ventricular fibrillation during myocardial ischemia and reperfusion was investigated in the anesthetized dog."3.66Effect of molsidomine on spontaneous ventricular fibrillation following myocardial ischemia and reperfusion in the dog. ( Kettenbach, B; Martorana, PA; Mogilev, AM; Nitz, RE, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martorana, PA2
Mogilev, AM1
Kettenbach, B1
Nitz, RE2

Reviews

1 review available for molsidomine and Ventricular Fibrillation

ArticleYear
The activity of molsidomine in experimental models of ischemic cardiac disease.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Electric Stimulation;

1985

Other Studies

1 other study available for molsidomine and Ventricular Fibrillation

ArticleYear
Effect of molsidomine on spontaneous ventricular fibrillation following myocardial ischemia and reperfusion in the dog.
    Advances in myocardiology, 1983, Volume: 4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Female; Ligation; Male; Molsidomine; Oxadiaz

1983