molsidomine has been researched along with Nerve Degeneration in 8 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashki, N | 1 |
| Hayes, KC | 1 |
| Bao, F | 2 |
| Lisý, V | 1 |
| Stastný, F | 1 |
| Liu, D | 1 |
| Kupershmidt, L | 1 |
| Amit, T | 1 |
| Bar-Am, O | 1 |
| Youdim, MB | 1 |
| Blumenfeld, Z | 1 |
| Lucius, R | 3 |
| Sievers, J | 3 |
| Hill, IE | 1 |
| Murray, C | 1 |
| Richard, J | 1 |
| Rasquinha, I | 1 |
| MacManus, JP | 1 |
| Rosenstiel, P | 1 |
8 other studies available for molsidomine and Nerve Degeneration
| Article | Year |
|---|---|
The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord.
Topics: Action Potentials; Animals; Axons; Cell Membrane; Dose-Response Relationship, Drug; Extracellular Fl | 2008 |
Nitric oxide synthase inhibition and glutamate binding in quinolinate-lesioned rat hippocampus.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding, Competitive; Cell Membra | 2002 |
Peroxynitrite generated in the rat spinal cord induces neuron death and neurological deficits.
Topics: Animals; Cell Death; Dyskinesia, Drug-Induced; Male; Microdialysis; Molsidomine; Nerve Degeneration; | 2002 |
The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases.
Topics: Activins; Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cell Line, Tumor; Cell Survival; | 2007 |
Postnatal retinal ganglion cells in vitro: protection against reactive oxygen species (ROS)-induced axonal degeneration by cocultured astrocytes.
Topics: Animals; Ascorbic Acid; Astrocytes; Axons; Coculture Techniques; Free Radical Scavengers; Iron; Mols | 1996 |
YVAD protect post-natal retinal ganglion cells against axotomy-induced but not free radical-induced axonal degeneration in vitro.
Topics: Animals; Apoptosis; Axons; Free Radicals; Mice; Molsidomine; Nerve Degeneration; Nerve Regeneration; | 1997 |
Despite the internucleosomal cleavage of DNA, reactive oxygen species do not produce other markers of apoptosis in cultured neurons.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspases; Cell Nucleus; Cholinesterase Inhibitors; Com | 2000 |
(-)-Deprenyl fails to promote axonal regeneration of retinal ganglion cells in vitro and in vivo.
Topics: Animals; Axons; Brain-Derived Neurotrophic Factor; Cell Survival; Free Radicals; Ganglia, Spinal; GA | 2002 |