Page last updated: 2024-10-31

molsidomine and Kidney Diseases

molsidomine has been researched along with Kidney Diseases in 6 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"In fawn-hooded hypertensive (FHH) rats, a model of hypertension, impaired preglomerular resistance, hyperfiltration, and progressive renal injury, we recently observed that supporting perinatal nitric oxide (NO) availability with the NO donor molsidomine persistently reduced blood pressure (BP) and ameliorated renal injury in male and female offspring."3.76Perinatal micronutrient supplements ameliorate hypertension and proteinuria in adult fawn-hooded hypertensive rats. ( Braam, B; Goldschmeding, R; Joles, JA; Koeners, MP; van der Giezen, DM, 2010)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jung, M1
Hotter, G1
Viñas, JL1
Sola, A1
Koeners, MP1
Braam, B2
van der Giezen, DM1
Goldschmeding, R2
Joles, JA2
Bongartz, LG1
Verhaar, MC1
Cramer, MJ1
Gaillard, CA1
Steendijk, P1
Doevendans, PA1
Büyükbayram, H1
Oztürk, H1
Kara, IH1
Arslan, A1
Chander, V2
Chopra, K2

Other Studies

6 other studies available for molsidomine and Kidney Diseases

ArticleYear
Cisplatin upregulates mitochondrial nitric oxide synthase and peroxynitrite formation to promote renal injury.
    Toxicology and applied pharmacology, 2009, Jan-15, Volume: 234, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cisplatin; Coloring Agents;

2009
Perinatal micronutrient supplements ameliorate hypertension and proteinuria in adult fawn-hooded hypertensive rats.
    American journal of hypertension, 2010, Volume: 23, Issue:7

    Topics: Animals; Arginine; Ascorbic Acid; Blood Pressure; Dietary Supplements; Female; Hypertension; Kidney

2010
The nitric oxide donor molsidomine rescues cardiac function in rats with chronic kidney disease and cardiac dysfunction.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:6

    Topics: Administration, Oral; Animals; Biomarkers; Cardiotonic Agents; Creatinine; Disease Models, Animal; G

2010
Does the analysis based on a histological and immunohistochemical grading system in the model of BDL kidney allow the quantification of the degree of injury?
    Renal failure, 2004, Volume: 26, Issue:5

    Topics: Animals; Cholestasis, Extrahepatic; Enzyme Inhibitors; Kidney; Kidney Diseases; Male; Models, Animal

2004
Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxide.
    Toxicology, 2005, Feb-28, Volume: 207, Issue:3

    Topics: Administration, Oral; Animals; Arginine; Cyclosporine; Dose-Response Relationship, Drug; Drinking; D

2005
Renal protective effect of molsidomine and L-arginine in ischemia-reperfusion induced injury in rats.
    The Journal of surgical research, 2005, Volume: 128, Issue:1

    Topics: Animals; Arginine; Kidney; Kidney Diseases; Male; Models, Animal; Molsidomine; Nephrectomy; Nitric O

2005