molsidomine has been researched along with Kashin-Beck Disease in 2 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Kashin-Beck Disease: Disabling osteochondrodysplasia with OSTEOSCLEROSIS, cone-shaped METAPHYSIS, and shortening of the DIAPHYSIS. It is endemic in parts of Siberia and northern China. Mineral deficiencies (e.g., selenium, iodine), fungal cereal contamination, and water contamination may be contributing factors in its etiology.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Fang, Q | 1 |
| Wang, M | 2 |
| Wang, W | 1 |
| Zhang, M | 2 |
| Zhang, D | 2 |
| He, Y | 2 |
| Zhang, Y | 2 |
| Wang, H | 1 |
| Otero, M | 2 |
| Ma, T | 1 |
| Chen, J | 2 |
| Jiang, Z | 1 |
2 other studies available for molsidomine and Kashin-Beck Disease
| Article | Year |
|---|---|
FGF8 and FGFR3 are up-regulated in hypertrophic chondrocytes: Association with chondrocyte death in deep zone of Kashin-Beck disease.
Topics: Animals; Biomarkers; Cartilage, Articular; Cell Death; Cell Differentiation; Cell Line; Child; Child | 2018 |
3-morpholinosydnonimine (SIN-1)-induced oxidative stress leads to necrosis in hypertrophic chondrocytes in vitro.
Topics: Animals; Apoptosis; Cartilage; Case-Control Studies; Cell Line; Cell Survival; Chondrocytes; Dose-Re | 2018 |