molsidomine has been researched along with Ischemia in 9 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aim of this experimental study is to verify the protective effect of molsidomine on the renal function and structural modifications in the ischemia-reperfusion rat kidney." | 7.71 | The effects of the nitric oxide donor molsidomine prevent in warm ischemia-reperfusion injury of the rat renal--a functional and histophatological study. ( Aldemir, M; Büyükbayram, H; Dokucu, AI; Otçu, S; Oztürk, H, 2001) |
| " An antiallodynic topical combination of apraclonidine + lisofylline was also found to effectively relieve depressed postocclusive reactive hyperemia in CPIP rats (N = 61) and to increase formazan production in postischemic tissues (skin and muscle) (N = 56)." | 3.80 | Topical combinations to treat microvascular dysfunction of chronic postischemia pain. ( Abaji, R; Coderre, TJ; Laferrière, A; Ragavendran, JV; Tsai, CY, 2014) |
| " To determine the level of NO in the cochlea after 20 to 120 min of ischemia, nitrites/nitrates in the perilymph were measured." | 3.71 | Effects of nitric oxide on normal and ischemic cochlea of the guinea pig. ( Leong, SK; Ruan, RS; Yeoh, KH, 2001) |
| "Aim of this experimental study is to verify the protective effect of molsidomine on the renal function and structural modifications in the ischemia-reperfusion rat kidney." | 3.71 | The effects of the nitric oxide donor molsidomine prevent in warm ischemia-reperfusion injury of the rat renal--a functional and histophatological study. ( Aldemir, M; Büyükbayram, H; Dokucu, AI; Otçu, S; Oztürk, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laferrière, A | 1 |
| Abaji, R | 1 |
| Tsai, CY | 1 |
| Ragavendran, JV | 1 |
| Coderre, TJ | 1 |
| Ozturk, H | 2 |
| Buyukbayram, H | 2 |
| Ozdemir, E | 1 |
| Ketani, A | 1 |
| Gurel, A | 1 |
| Onen, A | 1 |
| Otçu, S | 2 |
| Mastrodimou, N | 1 |
| Kiagiadaki, F | 1 |
| Thermos, K | 1 |
| Payne, D | 1 |
| Kubes, P | 1 |
| Bieroń, K | 1 |
| Grodzińska, L | 1 |
| Kostka-Trabka, E | 1 |
| Gryglewski, RJ | 1 |
| Yokoyama, I | 1 |
| Hayashi, S | 1 |
| Kobayashi, T | 1 |
| Negita, M | 1 |
| Namii, Y | 1 |
| Katayama, A | 1 |
| Nagasaka, T | 1 |
| Koike, C | 1 |
| Tachi, Y | 1 |
| Hayakawa, A | 1 |
| Tajiri, H | 1 |
| Takagi, H | 1 |
| Lepore, DA | 1 |
| Hurley, JV | 1 |
| Stewart, AG | 1 |
| Morrison, WA | 1 |
| Anderson, RL | 1 |
| Ruan, RS | 1 |
| Leong, SK | 1 |
| Yeoh, KH | 1 |
| Aldemir, M | 1 |
| Dokucu, AI | 1 |
1 trial available for molsidomine and Ischemia
| Article | Year |
|---|---|
Prostacyclin and molsidomine synergise in their fibrinolytic and anti-platelet actions in patients with peripheral arterial disease.
Topics: Aged; Arteriosclerosis Obliterans; Blood Pressure; Drug Synergism; Epoprostenol; Fibrinolysis; Human | 1993 |
8 other studies available for molsidomine and Ischemia
| Article | Year |
|---|---|
Topical combinations to treat microvascular dysfunction of chronic postischemia pain.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Animals; Capillaries; Chemistry, Phar | 2014 |
The effects of nitric oxide on the expression of cell adhesion molecules (ICAM-1, UEA-1, and tenascin) in rats with unilateral testicular torsion.
Topics: Animals; Cell Adhesion Molecules; Gene Expression Regulation; Infertility, Male; Intercellular Adhes | 2003 |
The role of nitric oxide and cGMP in somatostatin's protection against retinal ischemia.
Topics: Animals; Choline O-Acetyltransferase; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitor | 2008 |
Nitric oxide donors reduce the rise in reperfusion-induced intestinal mucosal permeability.
Topics: Animals; Cats; Cyclic GMP; Intestinal Mucosa; Intestines; Ischemia; Molsidomine; Nitric Oxide; Nitro | 1993 |
Hepatocyte apoptosis and cytosolic calcium dynamics in ischemic injury.
Topics: Animals; Apoptosis; Cells, Cultured; DNA Fragmentation; Ischemia; Liver; Mice; Mice, Inbred BALB C; | 1997 |
Prior heat stress improves survival of ischemic-reperfused skeletal muscle in vivo.
Topics: Animals; Cell Survival; Cells, Cultured; Clone Cells; Heat-Shock Response; Hot Temperature; HSP70 He | 2000 |
Effects of nitric oxide on normal and ischemic cochlea of the guinea pig.
Topics: Animals; Catalase; Cell Count; Cochlea; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitor | 2001 |
The effects of the nitric oxide donor molsidomine prevent in warm ischemia-reperfusion injury of the rat renal--a functional and histophatological study.
Topics: Animals; Creatinine; Ischemia; Kidney; Male; Models, Animal; Molsidomine; Nephrectomy; NG-Nitroargin | 2001 |