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molsidomine and Hypertrophy, Right Ventricular

molsidomine has been researched along with Hypertrophy, Right Ventricular in 3 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Hypertrophy, Right Ventricular: Enlargement of the RIGHT VENTRICLE of the heart. This increase in ventricular mass is often attributed to PULMONARY HYPERTENSION and is a contributor to cardiovascular morbidity and mortality.

Research Excerpts

ExcerptRelevanceReference
"Monocrotaline (MCT)-induced pulmonary hypertension (PH) is associated with impaired endothelium-dependent nitric oxide (NO)-mediated relaxation."7.69Role of inhibition of nitric oxide production in monocrotaline-induced pulmonary hypertension. ( Gewitz, MH; Gloster, ES; Mathew, R; Sundararajan, T; Thompson, CI; Zeballos, GA, 1997)
"Monocrotaline (MCT)-induced pulmonary hypertension (PH) is associated with impaired endothelium-dependent nitric oxide (NO)-mediated relaxation."3.69Role of inhibition of nitric oxide production in monocrotaline-induced pulmonary hypertension. ( Gewitz, MH; Gloster, ES; Mathew, R; Sundararajan, T; Thompson, CI; Zeballos, GA, 1997)
"4."1.32The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats. ( de Dam, MY; Elmedal, B; Mulvany, MJ; Simonsen, U, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elmedal, B1
de Dam, MY1
Mulvany, MJ1
Simonsen, U1
Schwenke, DO1
Pearson, JT1
Tsuchimochi, H1
Mori, H1
Shirai, M1
Mathew, R1
Gloster, ES1
Sundararajan, T1
Thompson, CI1
Zeballos, GA1
Gewitz, MH1

Other Studies

3 other studies available for molsidomine and Hypertrophy, Right Ventricular

ArticleYear
The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Administration, O

2004
Exogenous nitric oxide centrally enhances pulmonary reactivity in the normal and hypertensive rat.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:11

    Topics: Animals; Blood Pressure; Cardiac Output; Central Nervous System; Heart Rate; Hypertension, Pulmonary

2005
Role of inhibition of nitric oxide production in monocrotaline-induced pulmonary hypertension.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 82, Issue:5

    Topics: Animals; Arterioles; Blood Pressure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Inject

1997