molsidomine has been researched along with Hypertension, Renovascular in 2 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Hypertension, Renovascular: Hypertension due to RENAL ARTERY OBSTRUCTION or compression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We tested the hypothesis that increasing myocardial cyclic GMP levels would reduce myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship." | 7.69 | Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy. ( Naim, KL; Rabindranauth, P; Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR, 1997) |
| "We tested the hypothesis that increasing myocardial cyclic GMP levels would reduce myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship." | 3.69 | Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy. ( Naim, KL; Rabindranauth, P; Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rabindranauth, P | 1 |
| Naim, KL | 1 |
| Scholz, PM | 1 |
| Tse, J | 1 |
| Sadoff, JD | 1 |
| Weiss, HR | 1 |
| Van de Voorde, J | 1 |
| Claeys, M | 1 |
| Leusen, I | 1 |
2 other studies available for molsidomine and Hypertension, Renovascular
| Article | Year |
|---|---|
Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy.
Topics: Animals; Blood Gas Analysis; Cardiomegaly; Coronary Circulation; Cyclic GMP; Enzyme Inhibitors; Guan | 1997 |
Relaxations to endothelium-derived relaxing factor and the metabolite of molsidomine, SIN-1, in the aorta and the hindquarters of the rat.
Topics: Animals; Aorta; Aorta, Thoracic; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vasc | 1989 |