Page last updated: 2024-10-31

molsidomine and Gastric Ulcer

molsidomine has been researched along with Gastric Ulcer in 6 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"Aspirin (500 mg/kg) was given by gavage and repeated 2."1.31Protective effect of the nitric oxide donor molsidomine on indomethacin and aspirin-induced gastric injury in rats. ( Khuri, M; Mourad, FH; Nassar, CF; Shouaib, F, 2000)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
S Kwiecien, S1
Pawlik, MW1
Brzozowski, T2
Konturek, PC1
Sliwowski, Z1
Pawlik, WW1
Konturek, SJ2
KwiecieĊ„, S1
Konturek, PCh1
Yoshida, M1
Wakabayashi, G1
Ishikawa, H1
Kameyama, K1
Shimazu, M1
Tanabe, M1
Kawachi, S1
Kumai, K1
Kubota, T1
Otani, Y1
Saikawa, Y1
Sano, K1
Kitajima, M1
Asmawi, MZ1
Moilanen, E1
Annala, K1
Rahkonen, P1
Kankaanranta, H1
Mourad, FH1
Khuri, M1
Shouaib, F1
Nassar, CF1
Dembinska-Kiec, A1
Pallapies, D1
Simmet, T1
Peskar, BM1
Peskar, BA1

Other Studies

6 other studies available for molsidomine and Gastric Ulcer

ArticleYear
Nitric oxide (NO)-releasing aspirin and (NO) donors in protection of gastric mucosa against stress.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59 Suppl 2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Immersion; Lipid Peroxida

2008
The role of reactive oxygen species in action of nitric oxide-donors on stress-induced gastric mucosal lesions.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2002, Volume: 53, Issue:4 Pt 2

    Topics: Aldehydes; Animals; Aspirin; Gastric Mucosa; Lipid Peroxidation; Male; Malondialdehyde; Molsidomine;

2002
A possible defensive mechanism in the basal region of gastric mucosa and the healing of erosions.
    Clinical hemorheology and microcirculation, 2003, Volume: 29, Issue:3-4

    Topics: Animals; Burns; Enzyme Inhibitors; Esters; Exudates and Transudates; Gabexate; Gastric Mucosa; Guani

2003
Effects of nitric oxide donors GEA 3162 and SIN-1 on ethanol-induced gastric ulceration in rats.
    European journal of pharmacology, 1999, Jul-28, Volume: 378, Issue:1

    Topics: Animals; Blood Pressure; Dinoprostone; Ethanol; Gastric Mucosa; Male; Molsidomine; Nitric Oxide Dono

1999
Protective effect of the nitric oxide donor molsidomine on indomethacin and aspirin-induced gastric injury in rats.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Duodenal Ulcer; Gas

2000
Effect of carbenoxolone on the biological activity of nitric oxide: relation to gastroprotection.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Animals; Aorta; Arginine; Carbenoxolone; Gastric Mucosa; Humans; Iloprost; In Vitro Techniques; Male

1991