Page last updated: 2024-10-31

molsidomine and Diabetic Neuropathies

molsidomine has been researched along with Diabetic Neuropathies in 2 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"Treatment with molsidomine significantly improved motor coordination, paw withdrawal threshold, mechanical threshold, and nerve conduction velocity."1.62Molsidomine ameliorates diabetic peripheral neuropathy complications in Wistar rats. ( Minaz, N; Nayak B, P; Pasha, K, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Nayak B, P1
Minaz, N1
Pasha, K1
Thomsen, K1
Rubin, I1
Lauritzen, M1

Other Studies

2 other studies available for molsidomine and Diabetic Neuropathies

ArticleYear
Molsidomine ameliorates diabetic peripheral neuropathy complications in Wistar rats.
    Animal models and experimental medicine, 2021, Volume: 4, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Molsidomine; Oxidative Stress

2021
NO- and non-NO-, non-prostanoid-dependent vasodilatation in rat sciatic nerve during maturation and developing experimental diabetic neuropathy.
    The Journal of physiology, 2002, Sep-15, Volume: 543, Issue:Pt 3

    Topics: Acetylcholine; Animals; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibitors; Diabetic Neuropath

2002