molsidomine has been researched along with Coronary Vasospasm in 14 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A provocative test of coronary artery spasm caused by alkalosis was used to evaluate a possible anti-coronary artery spasm effect of molsidomine." | 7.67 | Prevention with molsidomine of coronary artery spasm caused by alkalosis. ( Degeorges, M; Guérin, F; Kahan, A; Pailleret, JJ; Weber, S, 1985) |
| "A test provocation of coronary artery spasm by alkalosis was used to evaluate a possible anti-coronary artery spasm effect of molsidomine." | 7.66 | [Molsidomine prevention of coronary artery spasm caused by alkalosis]. ( Degeorges, M; Guérin, F; Kahan, A; Pailleret, JJ; Weber, S, 1983) |
| "A provocative test of coronary artery spasm caused by alkalosis was used to evaluate a possible anti-coronary artery spasm effect of molsidomine." | 3.67 | Prevention with molsidomine of coronary artery spasm caused by alkalosis. ( Degeorges, M; Guérin, F; Kahan, A; Pailleret, JJ; Weber, S, 1985) |
| "A test provocation of coronary artery spasm by alkalosis was used to evaluate a possible anti-coronary artery spasm effect of molsidomine." | 3.66 | [Molsidomine prevention of coronary artery spasm caused by alkalosis]. ( Degeorges, M; Guérin, F; Kahan, A; Pailleret, JJ; Weber, S, 1983) |
| " Major (coronary substrate, study design) and minor (measuring devices, methods of evaluation) methodological problems make it difficult to precisely evaluate pharmacological effects such as dose-response relationship, duration of action, and selective responses, and to compare the effects of different drugs." | 2.38 | Response of coronary arteries to nitrates, the EDRF-donor SIN-1, and calcium antagonists. ( Kober, G; Schulz, W, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (50.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajlaoui, N | 1 |
| Tarragano, F | 1 |
| Raisky, P | 1 |
| Beaufils, P | 1 |
| Henry, P | 1 |
| Varenne, O | 1 |
| Jégou, A | 1 |
| Cohen, R | 1 |
| Empana, JP | 1 |
| Salengro, E | 1 |
| Ohanessian, A | 1 |
| Gaultier, C | 1 |
| Allouch, P | 1 |
| Walspurger, S | 1 |
| Margot, O | 1 |
| El Hallack, A | 1 |
| Jouven, X | 1 |
| Weber, S | 3 |
| Spaulding, C | 1 |
| Cheng, TO | 1 |
| Kahan, A | 2 |
| Pailleret, JJ | 2 |
| Guérin, F | 2 |
| Degeorges, M | 2 |
| Schulz, W | 2 |
| Kober, G | 2 |
| Fournier, C | 1 |
| Boujon, B | 1 |
| Hebert, JL | 1 |
| Zamani, K | 1 |
| Grimon, G | 1 |
| Blondeau, M | 1 |
| Danchin, N | 1 |
| Juillière, Y | 1 |
| Anconina, J | 1 |
| Perrin, O | 1 |
| Selton-Suty, C | 1 |
| Cherrier, F | 1 |
| Drobinski, G | 1 |
| Montalescot, G | 1 |
| Daune, M | 1 |
| Quarre, JP | 1 |
| Michalakis, G | 1 |
| Courtoy, JF | 1 |
| Leitold, M | 1 |
| Hader, S | 1 |
| Bernauer, R | 1 |
| Kaltenbach, M | 1 |
| Sobolski, J | 2 |
| Vandermoten, P | 2 |
| Stoupel, E | 2 |
| Berkenboom, G | 2 |
| Degre, S | 2 |
| Abramowicz, M | 1 |
2 reviews available for molsidomine and Coronary Vasospasm
| Article | Year |
|---|---|
[Coronary spastic angina refractory to optimal medical therapy treated by angioplasty and stenting. A case report and review of literature].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Vasospasm; Human | 2010 |
Response of coronary arteries to nitrates, the EDRF-donor SIN-1, and calcium antagonists.
Topics: Calcium Channel Blockers; Coronary Vasospasm; Coronary Vessels; Humans; Molsidomine; Nitrates; Nitro | 1991 |
3 trials available for molsidomine and Coronary Vasospasm
| Article | Year |
|---|---|
Prevention of arterial spasm during percutaneous coronary interventions through radial artery: the SPASM study.
Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Vasospasm; Double-Blind Method; Drug Therapy, Combina | 2006 |
Comparative effects of oral molsidomine and nifedipine on methylergometrine-induced coronary artery spasm.
Topics: Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Double-Blind Method; Ergonovine; Female; | 1991 |
Active and passive changes in coronary diameter after vasodilation with SIN-1, the active metabolite of molsidomine.
Topics: Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Humans; Molsidomine; Oxadiazoles; Sydnon | 1985 |
9 other studies available for molsidomine and Coronary Vasospasm
| Article | Year |
|---|---|
What is the SPASM study?
Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Vasospasm; Drug Therapy, Combination; Female; Humans; | 2007 |
[Molsidomine prevention of coronary artery spasm caused by alkalosis].
Topics: Alkalosis; Coronary Vasospasm; Electrocardiography; Female; Humans; Male; Middle Aged; Molsidomine; | 1983 |
Stunned myocardium following coronary spasm.
Topics: Coronary Angiography; Coronary Vasospasm; Echocardiography; Electrocardiography; Heart; Heart Ventri | 1991 |
Nitroglycerin-resistant coronary spasm treated with intracoronary linsidomine chlorhydrate (SIN-1).
Topics: Angiography; Coronary Vasospasm; Coronary Vessels; Humans; Injections, Intravenous; Male; Middle Age | 1990 |
[Unstable angina: recent findings and therapeutic applications].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Anticoagulants; Arteriosclerosis; Ca | 1987 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Is | 1986 |
The new long-acting coronary artery dilator molsidomine and its metabolite SIN-1.
Topics: Coronary Angiography; Coronary Vasospasm; Coronary Vessels; Female; Humans; Male; Middle Aged; Molsi | 1985 |
Prevention with molsidomine of coronary artery spasm caused by alkalosis.
Topics: Alkalosis; Blood Pressure; Coronary Vasospasm; Electrocardiography; Female; Heart Rate; Humans; Male | 1985 |
Comparison of the influence of nitrates, molsidomine and SIN-1, a molsidomine metabolite in acute coronary insufficiency.
Topics: Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Ergonovine; Humans; Molsidomine; Myocard | 1985 |