Page last updated: 2024-10-31

molsidomine and Coronary Heart Disease

molsidomine has been researched along with Coronary Heart Disease in 105 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"Pharmacokinetic measurements were performed in two groups of patients with coronary heart disease (CHD) after single and multiple dosing of 2 mg linsidomine (SIN 1)."9.07Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency. ( Degré, S; Gaertner, W; Ostrowski, J; Sennesael, J; Stolear, JC; Unger, P; Verbeelen, D; von Hattingberg, HM, 1993)
"In a randomised, crossover trial, 20 patients with electrocardiographically proven coronary heart disease and exercise-inducible angina pectoris, the antiischemic effect of gallopamil (3 x 50 mg) and molsidomine (2 x 2 mg) were studied."9.06[Gallopamil and molsidomine in patients with coronary heart disease. A comparative study]. ( Zebe, H, 1989)
"Combination treatment with isosorbide dinitrate with molsidomine in a slow-release form (in the nitrate free interval) showed a distinct improvement in patients with angina pectoris refractory to treatment with reduction of complaints."7.69[Influence of combination therapy (isosorbide dinitrate and molsidomine) on the incidence of angina pectoris in patients with coronary heart disease]. ( Ciopor, M; Fischer, A; Hess, OM; Turina, J, 1997)
" In 13 out of 16 patients (5 women, 11 men, 62 [53/71] years [median, 25%/75%-percentiles]) with chronic heart failure (NYHA stage II-III; median angiographic ejection fraction (EF) 55%) and coronary artery disease (stenosis of at least 75%) the development of tolerance under the continuous infusion of high doses of nitroglycerin (10 mg/h) was observed."7.68[Hemodynamic effect of molsidomine in coronary patients with heart failure with clinically manifest nitrate tolerance]. ( Bodemann, T; Danne, O; Eichstädt, H; Hochrein, H; Möckel, M; Müller, R; Piske, G; Störk, S; Störk, T, 1993)
"The haemodynamic effects of a single dose of intravenous molsidomine were assessed in 12 patients with severe coronary disease."7.67Haemodynamic effects of molsidomine in patients with severe chronic coronary disease. ( Augé, JM; Bosch, X; Crexells, C; Garcia, J; Lidón, RM; Oriol, A; Pina, C, 1985)
"To test the clinically supposed development of tolerance during chronic molsidomine therapy we studied a total of 11 patients with angiographically-proven coronary heart disease at rest and during ergometric exercise (supine position; submaximal, i."7.67Acute and chronic effects of molsidomine on pulmonary artery pressure and work capacity in patients with coronary heart disease. ( Eggeling, T; Hilger, HH; Jansen, W; Meyer, L; Tauchert, M, 1987)
"We performed a double-blind crossover study with molsidomine in 10 patients with coronary heart disease."7.66Effects of molsidomine on exercise tolerance in patients with coronary heart disease. ( Demaret, B; Denolin, H; Messin, R, 1983)
"To analyze the mechanisms of action of molsidomine, a new antianginal drug, 10 patients with coronary artery disease and exertional angina pectoris were studied."7.66Hemodynamic effects of molsidomine at rest and during submaximal and maximal exercise in patients with coronary artery disease limited by exertional angina pectoris. ( Brasseur, LA; Cosyns, J; Detry, JM; Melin, J; Rousseau, MF, 1981)
"The effect of molsidomine on hemodynamics and myocardial ischemia were studied in 48 patients with acute myocardial infarction."7.66[Effect of molsidomine on hemodynamics and myocardial ischemia in patients with acute myocardial infarction (author's transl)]. ( Bussmann, WD; Kaltenbach, M; Neidl, K, 1982)
"Pharmacokinetic measurements were performed in two groups of patients with coronary heart disease (CHD) after single and multiple dosing of 2 mg linsidomine (SIN 1)."5.07Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency. ( Degré, S; Gaertner, W; Ostrowski, J; Sennesael, J; Stolear, JC; Unger, P; Verbeelen, D; von Hattingberg, HM, 1993)
"In a randomised, crossover trial, 20 patients with electrocardiographically proven coronary heart disease and exercise-inducible angina pectoris, the antiischemic effect of gallopamil (3 x 50 mg) and molsidomine (2 x 2 mg) were studied."5.06[Gallopamil and molsidomine in patients with coronary heart disease. A comparative study]. ( Zebe, H, 1989)
"Studies of the efficacy of molsidomine, previously performed on our service, demonstrated that a clear antianginal effect in the longterm treatment of angina pectoris could only be achieved with a regimen of the standard 2 mg dose when given six times daily."5.05[Anti-ischemic effect of 8 mg molsidomin in retard form]. ( Blasini, R; Brügmann, U; Rudolph, W, 1984)
"Using a randomized, double-blind, crossover protocol, we compared the effects of oral molsidomine (Corvaton, 6 mg/day) and placebo, administered alternately for two 14-day periods, on the exercise tolerance of 25 outpatients with coronary heart disease."5.05Exercise tolerance in coronary patients: randomized trial of two-week treatment with molsidomine versus placebo. ( Messin, R, 1985)
"In the first study the hemodynamic effects of standard doses of molsidomine (2 mg intravenously), isosorbide dinitrate (ISDN) (5 mg sublingually), and nifedipine (20 mg sublingually) were assessed at rest and under exercise conditions in a group of 30 patients with coronary heart disease."5.05Hemodynamic effects of molsidomine, isosorbide dinitrate, and nifedipine at rest and during exercise. ( Dougherty, C; Rutsch, W; Schartl, M; Schmutzler, H, 1985)
"Organic nitrates still are one of the most important drug classes used in the treatment of an acute coronary syndrome and stable coronary artery disease as well as acute and chronic congestive heart failure."4.84[Recent findings on nitrates: their action, bioactivation and development of tolerance]. ( Münzel, T, 2008)
"Molsidomine is an established drug for the treatment of coronary heart disease."4.78Molsidomine. ( Reden, J, 1990)
"The cardioprotective and antithrombotic activity of molsidomine, a novel therapeutic agent for the treatment of coronary heart disease, was investigated in a series of animal models of myocardial ischemia."4.77The activity of molsidomine in experimental models of ischemic cardiac disease. ( Martorana, PA; Nitz, RE, 1985)
"Combination treatment with isosorbide dinitrate with molsidomine in a slow-release form (in the nitrate free interval) showed a distinct improvement in patients with angina pectoris refractory to treatment with reduction of complaints."3.69[Influence of combination therapy (isosorbide dinitrate and molsidomine) on the incidence of angina pectoris in patients with coronary heart disease]. ( Ciopor, M; Fischer, A; Hess, OM; Turina, J, 1997)
" In 13 out of 16 patients (5 women, 11 men, 62 [53/71] years [median, 25%/75%-percentiles]) with chronic heart failure (NYHA stage II-III; median angiographic ejection fraction (EF) 55%) and coronary artery disease (stenosis of at least 75%) the development of tolerance under the continuous infusion of high doses of nitroglycerin (10 mg/h) was observed."3.68[Hemodynamic effect of molsidomine in coronary patients with heart failure with clinically manifest nitrate tolerance]. ( Bodemann, T; Danne, O; Eichstädt, H; Hochrein, H; Möckel, M; Müller, R; Piske, G; Störk, S; Störk, T, 1993)
"To test the clinically supposed development of tolerance during chronic molsidomine therapy we studied a total of 11 patients with angiographically-proven coronary heart disease at rest and during ergometric exercise (supine position; submaximal, i."3.67Acute and chronic effects of molsidomine on pulmonary artery pressure and work capacity in patients with coronary heart disease. ( Eggeling, T; Hilger, HH; Jansen, W; Meyer, L; Tauchert, M, 1987)
"The pharmacokinetics of molsidomine were investigated in the plasma and urine of healthy male volunteers and patients with coronary heart disease after intravenous and/or oral administration of different galenic dosage forms of molsidomine."3.67Pharmacokinetics of molsidomine in humans. ( Ostrowski, J; Resag, K, 1985)
"The haemodynamic effects of a single dose of intravenous molsidomine were assessed in 12 patients with severe coronary disease."3.67Haemodynamic effects of molsidomine in patients with severe chronic coronary disease. ( Augé, JM; Bosch, X; Crexells, C; Garcia, J; Lidón, RM; Oriol, A; Pina, C, 1985)
"The effect of molsidomine on hemodynamics and myocardial ischemia were studied in 48 patients with acute myocardial infarction."3.66[Effect of molsidomine on hemodynamics and myocardial ischemia in patients with acute myocardial infarction (author's transl)]. ( Bussmann, WD; Kaltenbach, M; Neidl, K, 1982)
"To analyze the mechanisms of action of molsidomine, a new antianginal drug, 10 patients with coronary artery disease and exertional angina pectoris were studied."3.66Hemodynamic effects of molsidomine at rest and during submaximal and maximal exercise in patients with coronary artery disease limited by exertional angina pectoris. ( Brasseur, LA; Cosyns, J; Detry, JM; Melin, J; Rousseau, MF, 1981)
") on platelet function, on the plasma concentrations of 6-oxo-PGF1 alpha, the stable metabolite of prostaglandin I2, and thromboxane B2, the stable metabolite of thromboxine A2 was determined in ten patients with coronary heart disease."3.66[Molsidomine, a coronary drug with platelet-aggregating inhibitory activity]. ( Punzengruber, C; Silberbauer, K; Sinzinger, H; Slany, J, 1982)
"We performed a double-blind crossover study with molsidomine in 10 patients with coronary heart disease."3.66Effects of molsidomine on exercise tolerance in patients with coronary heart disease. ( Demaret, B; Denolin, H; Messin, R, 1983)
" Up to 8 h after dosing in the morning, more marked and sustained effects were observed with the nitrate (ST at 2 h, -82%; p < 0."2.69Clinical comparison of antiischemic efficacy of isosorbide dinitrate and molsidomine. ( Beyerle, A; Lehmann, G; Reiniger, G; Schömig, A, 1998)
"Thus molsidomine has an early positive effect on FMD in addition to a delayed vasodilator effect."2.69Molsidomine improves flow-dependent vasodilation in brachial arteries of patients with coronary artery disease. ( Adnot, S; Belhassen, L; Benacerraf, S; Carville, C; Dubois-Randé, JL; Pelle, G; Sediame, S, 2000)
"Treatment with linsidomine and molsidomine was associated with a modest improvement in the long-term angiographic result after angioplasty but had no effect on clinical outcome."2.68Effect of the direct nitric oxide donors linsidomine and molsidomine on angiographic restenosis after coronary balloon angioplasty. The ACCORD Study. Angioplastic Coronaire Corvasal Diltiazem. ( Bassand, JP; Battaglia, S; Béard, T; Bertrand, B; Bertrand, ME; Boschat, J; Coste, P; Crochet, PD; Desveaux, B; Drobinski, G; Dubois-Randé, JL; Finet, G; Giraud, T; Grollier, G; Juillière, Y; Juliard, JM; Lablanche, JM; Le Breton, H; Leclercq, F; Letac, B; Livarek, B; Lusson, JR; Metzger, JP; Quiret, JC; Virot, P, 1997)
"Molsidomine was associated with a significant reduction of the left ventricular end-diastolic pressure and an increase in Vcf."2.66Preload or afterload reduction: which is more beneficial for patients with ischemic heart disease? ( Caralis, DG; Kyriakides, Z, 1988)
"In 28 patients with unstable angina pectoris biplane coronary angiography was performed in the acute stage."2.65[Dynamics of critical stenosis in patients with unstable angina pectoris]. ( Karsch, KR; Niemczyk, P; Seipel, L; Voelker, W, 1984)
" In general, due to a large therapeutic dose range, dosage adjustments are not required on the basis of clinical experience."1.29Clinical pharmacokinetics of molsidomine. ( Parnham, MJ; Rosenkranz, B; Winkelmann, BR, 1996)
"Combinations of antianginal drugs may be used for an additive effect against angina, but also to off-set unwanted effects of one drug with another, either by direct effects or by a reduction of dosage of each drug."1.27Interactions of vasodilators with calcium entry- and beta-blockers in patients with coronary heart disease. ( Adam, WE; Haerer, W; Henze, E; Hermann, T; Kohler, J; Kress, P; Stauch, M, 1986)
"Molsidomine protected the treated animals from early (10 min) post-ischaemic ventricular fibrillation (0 of 20 vs 6 of 20, P = 0."1.27Molsidomine prevents post-ischaemic ventricular fibrillation in dogs. ( Cano, JP; Guillen, JC; Jouve, R; Langlet, F; Puddu, PE; Rolland, PH; Serradimigni, A, 1986)
"Molsidomine was administered intraduodenally to anesthetized dogs which were instrumented for measurements of aortic and left ventricular (LV) pressures, coronary perfusion pressure, intramyocardial pressure in the subendocardium, and subendocardial and subepicardial myocardial blood flow in the ischemic and non-ischemic regions."1.27The effect of molsidomine on intramyocardial pressure and regional myocardial blood flow in the canine ischemic myocardium. ( Bito, K; Fukuhara, T; Kawakita, S; Kinoshita, M; Mashiro, I; Mitsunami, K; Motomura, M, 1985)

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199069 (65.71)18.7374
1990's32 (30.48)18.2507
2000's4 (3.81)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Münzel, T2
Genest, M1
Pochmalicki, G1
Zygelman, M2
Neukirch, F2
Mérillon, JP2
Dahan, M2
Trouillet, JL1
Juliard, JM3
Pansard, Y2
Gourgon, R2
Di Giacomo, G1
Nicolella, U1
Puligheddu, M1
Tripodi, A1
D'Ascoli, C1
Di Virgilio, D1
Berdeaux, A1
Giudicelli, JF1
Blasini, R1
Brügmann, U1
Rudolph, W5
Fach, WA2
Becker, HJ1
Thulesius, O1
Strasser, R2
Klepzig, H3
Ostrowski, J4
Resag, K3
Osterspey, A4
Jansen, W5
Tauchert, M5
Schell, U2
Fuchs, M2
Hombach, V2
Hilger, HH4
Poincelot, B1
Russo-Marie, F1
Romano, M1
de Caprio, L1
Meccariello, P1
Cuomo, S1
Baldini, F1
D'Ascia, C1
Steinberg, G1
Chiariello, M1
Karsch, KR1
Niemczyk, P1
Voelker, W1
Seipel, L1
Kuz'ko, NV1
Schulz, W1
Wendt, T1
Scherer, D1
Kober, G3
Nitz, RE2
Mogilev, AM1
Göbel, H1
Messin, R2
Demaret, B1
Denolin, H1
Halawa, B1
Michel, PL1
Squara, P1
Laurent, S1
Silberbauer, K1
Slany, J1
Sinzinger, H1
Punzengruber, C1
Kaliman, J1
Uhlir, H1
Klicpera, M1
Gasilin, VS1
Kramer, AA1
Samoilenko, LE1
Gross, GJ1
Gharaibeh, M1
Meyer, J4
Sprauer, R1
Krebs, W1
Erbel, R3
Schweizer, P1
Effert, S1
Detry, JM1
Melin, J1
Brasseur, LA1
Cosyns, J1
Rousseau, MF1
Litvitskiĭ, PF1
Ol'binskaia, LI1
Sandrikov, VA1
Aksiuk, MA1
Fiedler, VB2
Bussmann, WD1
Neidl, K1
Kaltenbach, M1
Dubois-Rande, JL3
Dupouy, P1
Geschwind, H1
Castaigne, A1
Adnot, S2
Kostanecka, T1
Kenny, D1
Coughlan, MG1
Kampine, JP1
Montgomery, RR1
Bosnjak, ZJ1
Warltier, DC1
Hug, J1
Hasenfuss, G1
Wollschläger, H1
Just, HJ1
Bonzel, T1
Kurz, S1
Heitzer, T1
Luhmann, C1
Just, H1
Weimer, M1
Pizzulli, L1
Reichert, H1
Lüderitz, B1
Ferguson, JJ1
Bender, M1
Vallbracht, C1
Sievert, H1
Ohlmeier, H1
Gleichmann, U1
Sennesael, J1
Verbeelen, D1
Degré, S2
Unger, P2
Stolear, JC1
von Hattingberg, HM1
Gaertner, W1
Störk, T1
Möckel, M1
Störk, S1
Piske, G1
Danne, O1
Bodemann, T1
Müller, R1
Eichstädt, H1
Hochrein, H1
Jost, S4
Sturm, M1
Hausmann, D1
Lippolt, P1
Lichtlen, PR2
Rosenkranz, B1
Winkelmann, BR1
Parnham, MJ1
Dukát, A1
Lablanche, JM1
Grollier, G1
Lusson, JR1
Bassand, JP1
Drobinski, G1
Bertrand, B1
Battaglia, S1
Desveaux, B1
Juillière, Y1
Metzger, JP1
Coste, P1
Quiret, JC1
Crochet, PD1
Letac, B1
Boschat, J1
Virot, P1
Finet, G1
Le Breton, H1
Livarek, B1
Leclercq, F1
Béard, T1
Giraud, T1
Bertrand, ME1
Lehmann, G1
Reiniger, G1
Beyerle, A3
Schömig, A1
Ciopor, M1
Fischer, A1
Turina, J1
Hess, OM1
Feld, S1
Smalling, RW1
Belhassen, L1
Carville, C1
Pelle, G1
Sediame, S1
Benacerraf, S1
Gryglewski, RJ1
Swies, J1
Leone, A1
Staroukine, M1
Berkenboom, G1
Darius, H3
Beisiegel, B1
Rupprecht, HJ2
Hafner, G1
Pop, T2
Treese, N1
Frey, AW1
Haider, M1
Rösch, A1
Rösch, R1
Drummer, C1
Gerzer, R2
Theisen, K2
Dirschinger, J2
Caralis, DG2
Kyriakides, Z2
Ioakimides, C1
Vrolix, M1
Piessens, J1
De Geest, H1
Rafflenbeul, W2
Reil, GH1
Gulba, D2
Knop, I2
Hecker, H2
Böhme, E1
Reden, J1
Reil, G1
Auricchio, A1
Frombach, R1
Lichtlen, P1
Haufe, MC1
Weil, J1
Heim, JM1
Ernst, JE1
Kyriakidis, M1
Vyssoulis, G1
Sfikakis, P1
Kyriakidis, C1
Pitsavos, C1
Valsamis, K1
Nomikos, V1
Toutouzas, P1
Brovko, EA1
Denisiuk, VI1
Kolesnik, PF1
Zebe, H1
Nemirovskaia, MA1
Zharov, EI1
Vertkin, AL1
Alekperov, EZ1
Kipshidze, NN1
Chumburidze, VB1
Tomov, I1
Alpert, JS1
Mosca, SM1
Gelpi, RJ1
Cingolani, HE1
Erbel, E1
Schmucker, B1
Reusch, U1
Stauch, M2
Haerer, W2
Henze, E1
Hermann, T1
Kohler, J1
Kress, P1
Adam, WE2
Meyer, L2
Eggeling, T2
Krüger, R1
Gilfrich, HJ1
Sterkowicz, S1
Weill, D1
Maclouf, J1
Vallantin, X1
Wautier, JL1
Serruys, PW1
Deckers, JW1
Luijten, HE1
Reiber, JH1
Tijssen, JG1
Chadha, D1
Hugenholtz, PG1
Trifunović, S1
Pavlović, K1
Cano, JP1
Guillen, JC1
Jouve, R1
Langlet, F1
Puddu, PE1
Rolland, PH1
Serradimigni, A1
Vakaliuk, IP1
Schartl, M1
Dougherty, C1
Rutsch, W1
Schmutzler, H1
Rogg-Dussler, G1
Sigel, H1
Kinoshita, M1
Mashiro, I1
Mitsunami, K1
Fukuhara, T1
Motomura, M1
Bito, K1
Kawakita, S1
Crexells, C1
Lidón, RM1
Augé, JM1
Bosch, X1
Pina, C1
Garcia, J1
Oriol, A1
Tsujibayashi, T1
Niwa, A1
Taniguchi, K1
Takeuchi, J1
Gaul, G1
Voegele, D1
Brockmeier, D1
Goch, JH1
Rosiek, S1
Brzozowski, R1
Bała, T1
Tkaczewski, W1
Adamska-Dyniewska, H1
König, FK1
Grewe, R1
Wörz, K1
Martorana, PA1
Furkalo, NK1
Ivashchenko, TI1
Romanenko, AI1

Reviews

9 reviews available for molsidomine and Coronary Heart Disease

ArticleYear
[Recent findings on nitrates: their action, bioactivation and development of tolerance].
    Deutsche medizinische Wochenschrift (1946), 2008, Volume: 133, Issue:44

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Coronary Disease; Drug Tolerance; End

2008
[Acute coronary syndromes with ST-segment elevation].
    Presse medicale (Paris, France : 1983), 2004, May-22, Volume: 33, Issue:9 Pt 1

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Angioplasty, Balloon, Coronary; Angiotensin-Converti

2004
Cardiovascular pharmacology of molsidomine.
    Bibliotheca cardiologica, 1984, Issue:38

    Topics: Animals; Biological Availability; Coronary Disease; Heart; Liver; Molsidomine; Oxadiazoles; Sydnones

1984
Clinical comparison of nitrates and sydnonimines.
    European heart journal, 1991, Volume: 12 Suppl E

    Topics: Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; He

1991
[Pharmacology of molsidomine and its active metabolites].
    Medizinische Klinik (Munich, Germany : 1983), 1990, Volume: 85 Suppl 1

    Topics: Animals; Coronary Circulation; Coronary Disease; Cyclic AMP; Humans; Molsidomine; Muscle, Smooth, Va

1990
[Treatment of myocardial ischemia with molsidomine].
    Medizinische Klinik (Munich, Germany : 1983), 1990, Mar-15, Volume: 85, Issue:3

    Topics: Angina Pectoris; Coronary Disease; Electrocardiography; Humans; Molsidomine

1990
Molsidomine.
    Blood vessels, 1990, Volume: 27, Issue:2-5

    Topics: Animals; Coronary Circulation; Coronary Disease; Drug Tolerance; Humans; Molsidomine; Nitric Oxide;

1990
[Molsidomine in the treatment of ischemic heart disease].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1987, Oct-15, Volume: 40, Issue:20

    Topics: Coronary Disease; Humans; Molsidomine

1987
The activity of molsidomine in experimental models of ischemic cardiac disease.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Animals; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Electric Stimulation;

1985

Trials

30 trials available for molsidomine and Coronary Heart Disease

ArticleYear
[Anti-ischemic effect of 8 mg molsidomin in retard form].
    Herz, 1984, Volume: 9, Issue:6

    Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; D

1984
[Effect duration and dose-response relation of molsidomine in patients with coronary heart disease].
    Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:10

    Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Circulation; Coronary Disease; D

1984
[Hemodynamic effect of molsidomine in acute administration and as a long-term medication].
    Die Medizinische Welt, 1983, Apr-29, Volume: 34, Issue:17

    Topics: Antihypertensive Agents; Coronary Disease; Hemodynamics; Humans; Long-Term Care; Male; Middle Aged;

1983
Effects of long-term molsidomine treatment versus isosorbide dinitrate and placebo on exercise tolerance in stable angina.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:5

    Topics: Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans;

1984
[Dynamics of critical stenosis in patients with unstable angina pectoris].
    Zeitschrift fur Kardiologie, 1984, Volume: 73, Issue:9

    Topics: Angina Pectoris; Angina, Unstable; Coronary Angiography; Coronary Circulation; Coronary Disease; Hem

1984
[Diameter changes of epicardial coronary arteries and coronary stenoses after intracoronary application of SIN 1, a molsidomine metabolite].
    Zeitschrift fur Kardiologie, 1983, Volume: 72, Issue:7

    Topics: Coronary Disease; Coronary Vessels; Double-Blind Method; Humans; Injections, Intra-Arterial; Molsido

1983
Long-term treatment of patients with coronary heart disease using isosorbide dinitrate, nifedipine and molsidomine.
    Zeitschrift fur Kardiologie, 1983, Volume: 72 Suppl 3

    Topics: Adult; Blood Pressure; Coronary Disease; Drug Administration Schedule; Drug Tolerance; Hemodynamics;

1983
[Circadian variation of ischaemic ST lowering in exercise ECG (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1981, Apr-03, Volume: 106, Issue:14

    Topics: Adult; Blood Pressure; Circadian Rhythm; Coronary Disease; Double-Blind Method; Electrocardiography;

1981
[Long-term antihypertensive effect of delayed-action molsidomine].
    Zeitschrift fur Kardiologie, 1994, Volume: 83, Issue:9

    Topics: Blood Pressure; Blood Pressure Monitors; Coronary Disease; Delayed-Action Preparations; Dose-Respons

1994
[Coronary dilatation after intracoronary administration of SIN-1 and intravenous molsidomine administration].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Volume: 89 Suppl 2

    Topics: Adult; Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Coronary Vessels; Double-Blind

1994
Meeting highlights: nitric oxide donors.
    Circulation, 1994, Volume: 90, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Diltiazem; Humans; Isosorbide Dinitrate; Molsidomi

1994
SIN-1 has no direct myocardial anti-ischemic action.
    Clinical cardiology, 1993, Volume: 16, Issue:10

    Topics: Angioplasty, Balloon, Coronary; Coronary Circulation; Coronary Disease; Double-Blind Method; Electro

1993
Pharmacokinetics of linsidomine (SIN 1) after single and multiple intravenous short infusions in patients with renal insufficiency.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Coronary Disease; Drug Admi

1993
Effect of the direct nitric oxide donors linsidomine and molsidomine on angiographic restenosis after coronary balloon angioplasty. The ACCORD Study. Angioplastic Coronaire Corvasal Diltiazem.
    Circulation, 1997, Jan-07, Volume: 95, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Disease; Coronary Vessels; Dilt

1997
Clinical comparison of antiischemic efficacy of isosorbide dinitrate and molsidomine.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1

    Topics: Blood Pressure; Coronary Disease; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Meth

1998
Molsidomine improves flow-dependent vasodilation in brachial arteries of patients with coronary artery disease.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:4

    Topics: Blood Flow Velocity; Brachial Artery; Coronary Disease; Double-Blind Method; Endothelium, Vascular;

2000
Differences in the antiischaemic effects of molsidomine and isosorbide dinitrate.
    European heart journal, 1992, Volume: 13, Issue:5

    Topics: Coronary Disease; Hemodynamics; Humans; Isosorbide Dinitrate; Molsidomine

1992
[Modification of thrombocyte function in diagnostic and therapeutic interventions in cardiology].
    Zeitschrift fur Kardiologie, 1991, Volume: 80 Suppl 5

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Coronary Disease; Dose-Response Relationship, Drug; Double-

1991
[Acute and chronic effects of molsidomine in therapeutic coronary angioplasty].
    Medizinische Klinik (Munich, Germany : 1983), 1990, Volume: 85 Suppl 1

    Topics: Angioplasty, Balloon, Coronary; Coronary Circulation; Coronary Disease; Delayed-Action Preparations;

1990
[Gallopamil and molsidomine in patients with coronary heart disease. A comparative study].
    Fortschritte der Medizin, 1989, Feb-20, Volume: 107, Issue:5

    Topics: Clinical Trials as Topic; Coronary Disease; Electrocardiography; Exercise Test; Female; Gallopamil;

1989
[Effect of vasodilator agents on the effectiveness of the complex treatment of patients with ischemic heart disease and congestive heart failure].
    Kardiologiia, 1989, Volume: 29, Issue:4

    Topics: Aged; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Digoxin; Drug Synergism;

1989
[Molsidomine in rest and exercise conditions in coronary heart disease. Acute and long-term effects].
    Medizinische Klinik (Munich, Germany : 1983), 1986, Jun-20, Volume: 81, Issue:14

    Topics: Adult; Coronary Disease; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Long-Term Care; Middle

1986
Preload or afterload reduction: which is more beneficial for patients with ischemic heart disease?
    Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:1

    Topics: Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Molsidomine; Nifedipine; Random A

1988
[Treatment of stress-induced angina pectoris and chronic heart failure with molsidomine].
    Medizinische Klinik (Munich, Germany : 1983), 1986, Jan-31, Volume: 81, Issue:2

    Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Exercise Test; Hea

1986
[Acute and long-term effects of placebo and molsidomine on pulmonary artery pressure and on workload in patients with coronary heart disease].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Oct-07, Volume: 75, Issue:41

    Topics: Adult; Blood Pressure; Coronary Disease; Exercise Test; Humans; Male; Middle Aged; Molsidomine; Plac

1986
Hemodynamic effects of molsidomine, isosorbide dinitrate, and nifedipine at rest and during exercise.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Adult; Blood Pressure; Coronary Disease; Heart Rate; Hemodynamics; Humans; Isosorbide Dinitrate; Mid

1985
Exercise tolerance in coronary patients: randomized trial of two-week treatment with molsidomine versus placebo.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Adult; Aged; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Exercise Test; Female;

1985
Pharmacokinetics of an extended-release dosage form of molsidomine in patients with coronary heart disease.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:5

    Topics: Aged; Angina Pectoris; Biological Availability; Clinical Trials as Topic; Coronary Disease; Double-B

1985
[Use of molsidomine in patients with coronary disease].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1985, Jul-22, Volume: 40, Issue:29

    Topics: Adult; Clinical Trials as Topic; Coronary Disease; Humans; Male; Middle Aged; Molsidomine; Oxadiazol

1985
[Effectiveness and duration of effect of molsidomine and isosorbide dinitrate in peripheral circulation].
    Fortschritte der Medizin, 1985, Oct-10, Volume: 103, Issue:38

    Topics: Aged; Arterial Occlusive Diseases; Clinical Trials as Topic; Coronary Disease; Female; Hemodynamics;

1985

Other Studies

66 other studies available for molsidomine and Coronary Heart Disease

ArticleYear
[Effects of molsidomine during the cold test in stable coronary insufficiency under beta-blocker treatment].
    Archives des maladies du coeur et des vaisseaux, 1984, Volume: 77, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Cold Temperature; Coronary Disease; Hemodynamics; Humans;

1984
[Clinical evaluation of molsidomin in ischemic cardiopathy].
    La Clinica terapeutica, 1984, Oct-31, Volume: 111, Issue:2

    Topics: Aged; Coronary Disease; Drug Evaluation; Female; Humans; Male; Middle Aged; Molsidomine; Oxadiazoles

1984
[Redistribution of the coronary blood flow, functional improvement of the ischemic myocardium and reduction of the size of an experimental infarction by molsidomine].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:8

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Epoprostenol; Molsidomine; Oxadiazoles; Oxyge

1983
[Molsidomin in coronary disease. Clinico-pharmacokinetic correlation study on the effect of oral and sublingual therapy].
    MMW, Munchener medizinische Wochenschrift, 1983, Feb-25, Volume: 125, Issue:8

    Topics: Administration, Oral; Adult; Angina Pectoris; Coronary Disease; Double-Blind Method; Humans; Kinetic

1983
[Cellular mechanism of action of molsidomine. Bioinduction of prostacyclin].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:8

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cells, Cultured; Coronary Disease; Epoprostenol; Molsidomine;

1983
[Treatment with sidnonimine derivatives of chronic ischemic heart disease patients].
    Vrachebnoe delo, 1984, Issue:7

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluation; Female; H

1984
Anti-ischemic effects of molsidomine in an experimental model of coronary artery stenosis.
    Advances in myocardiology, 1983, Volume: 4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Coronary Disease; Dogs; Electrocardiography; Femal

1983
Effects of molsidomine on exercise tolerance in patients with coronary heart disease.
    International journal of cardiology, 1983, Volume: 3, Issue:2

    Topics: Aged; Coronary Disease; Double-Blind Method; Humans; Male; Middle Aged; Molsidomine; Oxadiazoles; Ox

1983
[Interactions between digoxin and amiodarone (Cordarone), verapamil (Isoptin) and melsidomine (Corvatone)].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Apr-11, Volume: 38, Issue:15

    Topics: Adult; Amiodarone; Cardiotonic Agents; Coronary Disease; Digoxin; Drug Interactions; Humans; Male; M

1983
[Hemodynamic and coronary effects of molsidomine in patients with stable coronary insufficiency in the basal state, during an atrial stimulation test and a cold test].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:8

    Topics: Adult; Aged; Atrial Function; Cold Temperature; Coronary Circulation; Coronary Disease; Electric Sti

1983
[Molsidomine, a coronary drug with platelet-aggregating inhibitory activity].
    Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:8

    Topics: Angina Pectoris; Blood Pressure; Coronary Disease; Epoprostenol; Female; Humans; Male; Molsidomine;

1982
[Therapy of coronary heart disease with molsidomine].
    MMW, Munchener medizinische Wochenschrift, 1981, Nov-13, Volume: 123, Issue:46

    Topics: Angina Pectoris; Coronary Disease; Electrocardiography; Humans; Male; Middle Aged; Molsidomine; Morp

1981
The effect of some antianginal drugs on the myocardial perfusion in patients with ischaemic heart disease.
    Cor et vasa, 1981, Volume: 23, Issue:6

    Topics: Adult; Angina Pectoris; Coronary Circulation; Coronary Disease; Coronary Vessels; Delayed-Action Pre

1981
Effect of molsidomine on coronary collateral blood flow in acute myocardial ischemia.
    European journal of pharmacology, 1980, Oct-03, Volume: 67, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Male; Molsidomine; Morp

1980
[The effect of molsidomine on left ventricular function in coronary heart disease (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Aug-29, Volume: 105, Issue:35

    Topics: Adult; Angina Pectoris; Blood Pressure; Cardiac Volume; Computers; Coronary Disease; Female; Heart;

1980
Hemodynamic effects of molsidomine at rest and during submaximal and maximal exercise in patients with coronary artery disease limited by exertional angina pectoris.
    The American journal of cardiology, 1981, Volume: 47, Issue:1

    Topics: Adult; Angina Pectoris; Cardiac Output; Coronary Disease; Exercise Test; Heart Rate; Hemodynamics; H

1981
[Effect of molsidomine on cardiac function in experimental transitory coronary insufficiency].
    Kardiologiia, 1981, Volume: 21, Issue:4

    Topics: Acute Disease; Animals; Coronary Disease; Dogs; Drug Evaluation, Preclinical; Female; Heart; Male; M

1981
Effects of molsidomine on coronary artery thrombosis and myocardial ischemia in acute canine experiments.
    European journal of pharmacology, 1981, Jul-17, Volume: 73, Issue:1

    Topics: Animals; Blood Coagulation; Coronary Disease; Disease Models, Animal; Dogs; Female; Hemodynamics; Ma

1981
[Effect of molsidomine on hemodynamics and myocardial ischemia in patients with acute myocardial infarction (author's transl)].
    Klinische Wochenschrift, 1982, Jan-15, Volume: 60, Issue:2

    Topics: Administration, Oral; Blood Pressure; Cardiac Output; Coronary Disease; Heart Rate; Hemodynamics; Hu

1982
Reduction of occlusive coronary artery thrombosis and myocardial ischemia by molsidomine in anesthetized dogs.
    Canadian journal of physiology and pharmacology, 1982, Volume: 60, Issue:8

    Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Electric Stimulation; Electrocardiography; Female;

1982
Intracoronary linsidomine abolishes acetylcholine-induced vasoconstriction of epicardial coronary arteries.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:3

    Topics: Acetylcholine; Coronary Circulation; Coronary Disease; Coronary Vessels; Dose-Response Relationship,

1993
Cultured endothelial cells restore vasodilator responses to coronary arteries with impaired endothelial function and alter the response to a nitric oxide donor.
    Pharmacology, 1994, Volume: 49, Issue:4

    Topics: Animals; Arginine; Blood Flow Velocity; Calcimycin; Cells, Cultured; Coronary Circulation; Coronary

1994
[Effects of intravenous administration of nitroglycerin and SIN-1 or molsidomine on epicardial arterial diameter in patients with stable coronary heart disease].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Volume: 89 Suppl 2

    Topics: Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Drug Administration Schedu

1994
[Is there a drug interaction between heparin and molsidomine?].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Volume: 89 Suppl 2

    Topics: Adult; Aged; Coronary Disease; Drug Interactions; Drug Therapy, Combination; Female; Heparin; Humans

1994
[Molsidomine and bladder cancer: is there a connection?].
    Deutsche medizinische Wochenschrift (1946), 1993, Nov-26, Volume: 118, Issue:47

    Topics: Aged; Coronary Disease; Humans; Male; Molsidomine; Time Factors; Urinary Bladder Neoplasms

1993
[Hemodynamic effect of molsidomine in coronary patients with heart failure with clinically manifest nitrate tolerance].
    Zeitschrift fur Kardiologie, 1993, Volume: 82, Issue:5

    Topics: Aged; Coronary Disease; Drug Therapy, Combination; Drug Tolerance; Female; Heart Failure; Hemodynami

1993
Standardization of coronary vasomotor tone with intracoronary nitroglycerin.
    The American journal of cardiology, 1996, Jul-01, Volume: 78, Issue:1

    Topics: Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Coronary Angiography; Coronary Disea

1996
Clinical pharmacokinetics of molsidomine.
    Clinical pharmacokinetics, 1996, Volume: 30, Issue:5

    Topics: Absorption; Administration, Oral; Age Factors; Angina Pectoris; Coronary Disease; Humans; Injections

1996
[Clinical use of molsidomine in the treatment of patients with coronary artery diseases].
    Bratislavske lekarske listy, 1996, Volume: 97, Issue:8

    Topics: Coronary Disease; Humans; Molsidomine; Vasodilator Agents

1996
[Influence of combination therapy (isosorbide dinitrate and molsidomine) on the incidence of angina pectoris in patients with coronary heart disease].
    Praxis, 1997, Nov-19, Volume: 86, Issue:47

    Topics: Aged; Angina Pectoris; Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, Dr

1997
Gastroepiploic bypass graft stenting.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 1999, Volume: 46, Issue:1

    Topics: Angina, Unstable; Arteries; Coronary Artery Bypass; Coronary Disease; Graft Occlusion, Vascular; Hum

1999
[Erectile dysfunction. Help also for cardiac patients].
    MMW Fortschritte der Medizin, 2001, Oct-11, Volume: 143, Issue:41

    Topics: Apomorphine; Contraindications; Coronary Disease; Drug Interactions; Erectile Dysfunction; Humans; M

2001
Cardioprotection by molsidomine and iloprost in myocardial ischemia in anaesthetized cats.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Animals; Blood Platelets; Blood Pressure; Cats; Coronary Disease; Coronary Vessels; Cyclic GMP; Elec

1992
Hemodynamic response to molsidomine in patients with ischemic cardiomyopathy tolerant to isosorbide dinitrate.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:6

    Topics: Aged; Animals; Cardiomyopathy, Dilated; Coronary Disease; Drug Tolerance; Female; Hemodynamics; Huma

1991
[Inhibition of thrombocyte function in coronary heart disease. Results with molsidomine (Corvaton)].
    Zeitschrift fur Kardiologie, 1991, Volume: 80 Suppl 5

    Topics: Blood Platelets; Coronary Disease; Humans; Molsidomine

1991
[Effect of molsidomine on thrombocyte aggregation in unstable angina pectoris after parenteral administration of nitroglycerin].
    Zeitschrift fur Kardiologie, 1991, Volume: 80 Suppl 5

    Topics: Angina, Unstable; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hum

1991
Acute hemodynamic effects of molsidomine in patients with ischemic cardiomyopathy.
    Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:1

    Topics: Adult; Aged; Coronary Disease; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Molsi

1991
Torsades de pointes after intracoronary papaverine.
    European heart journal, 1991, Volume: 12, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Electro

1991
Reproducible uniform coronary vasomotor tone with nitrocompounds: prerequisite of quantitative coronary angiographic trials.
    Catheterization and cardiovascular diagnosis, 1990, Volume: 20, Issue:3

    Topics: Angiography; Coronary Angiography; Coronary Disease; Female; Humans; Image Interpretation, Computer-

1990
Coronary vasodilation with nitrocompounds--is there a maximum?
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 2

    Topics: Administration, Sublingual; Adult; Aged; Coronary Circulation; Coronary Disease; Dose-Response Relat

1989
[Hemodynamic and medicamentous modification of stimulated atrial natriuretic factor secretion].
    Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:8

    Topics: Adult; Aged; Atenolol; Atrial Natriuretic Factor; Blood Pressure; Cardiac Catheterization; Cardiac P

1989
Comparison of haemodynamic effects of nifedipine and molsidomine in patients with coronary artery disease.
    European journal of clinical pharmacology, 1989, Volume: 37, Issue:5

    Topics: Adult; Aged; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Molsidomine; Nifedip

1989
[The effect of molsidomine on the conjunctival microcirculation in patients with ischemic heart disease].
    Vrachebnoe delo, 1989, Issue:11

    Topics: Adult; Aged; Angina Pectoris; Conjunctiva; Coronary Disease; Drug Evaluation; Female; Humans; Male;

1989
[Effect of molsidomine preparations on the contractile function of the myocardium and coronary circulation in patients with ischemic heart disease complicated by heart failure after isometric load].
    Kardiologiia, 1989, Volume: 29, Issue:4

    Topics: Administration, Oral; Administration, Sublingual; Adult; Aged; Cardiomyopathy, Dilated; Coronary Cir

1989
[Various aspects of drug therapy of chronic forms of ischemic heart disease].
    Kardiologiia, 1985, Volume: 25, Issue:9

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Angina Pectoris; Calcium Channel Block

1985
[Antiaggregants of thrombocytes in ischemic heart disease].
    Vutreshni bolesti, 1985, Volume: 24, Issue:5

    Topics: Adrenergic beta-Antagonists; Aspirin; Coronary Disease; Dipyridamole; Fibrinolytic Agents; Humans; M

1985
The pharmacologic management of coronary artery disease in 1986.
    Heart & lung : the journal of critical care, 1986, Volume: 15, Issue:6

    Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Calcium Channel Blockers; Coronary Disease

1986
[Substituted sydnonimines: hemodynamic effects and distribution of coronary blood flow in normal and ischemic myocardium].
    Acta physiologica et pharmacologica latinoamericana : organo de la Asociacion Latinoamericana de Ciencias Fisiologicas y de la Asociacion Latinoamericana de Farmacologia, 1985, Volume: 35, Issue:3

    Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Coronary Disease; Depression, Chemica

1985
[Anti-ischemic effects of SIN-1, a molsidomine metabolite, during coronary angioplasty and antiplatelet effects in humans].
    Presse medicale (Paris, France : 1983), 1988, May-25, Volume: 17, Issue:20

    Topics: Adenosine Triphosphate; Administration, Oral; Angioplasty, Balloon; Coronary Disease; Coronary Vesse

1988
Interactions of vasodilators with calcium entry- and beta-blockers in patients with coronary heart disease.
    Zeitschrift fur Kardiologie, 1986, Volume: 75 Suppl 3

    Topics: Bupranolol; Calcium Channel Blockers; Coronary Disease; Drug Interactions; Drug Therapy, Combination

1986
[Problems in acute therapy of coronary heart disease using drugs that reduce preload and afterload].
    Medizinische Klinik (Munich, Germany : 1983), 1987, Volume: 1

    Topics: Coronary Disease; Heart Failure; Hemodynamics; Humans; Hypertension; Molsidomine; Nifedipine; Nitrog

1987
[Problems in long-term therapy of coronary heart disease: pharmacotherapy].
    Medizinische Klinik (Munich, Germany : 1983), 1987, Volume: 1

    Topics: Angina Pectoris; Coronary Disease; Humans; Long-Term Care; Molsidomine

1987
[Ex vivo study of blood platelet activation in healthy subjects or coronary disease patients after oral intake of molsidomine].
    Pathologie-biologie, 1987, Volume: 35, Issue:2 Pt 2

    Topics: Administration, Oral; Adult; Blood Platelets; Coronary Disease; Female; Humans; Male; Molsidomine; P

1987
Long-acting coronary vasodilatory action of the molsidomine metabolite Sin 1: a quantitative angiographic study.
    European heart journal, 1987, Volume: 8, Issue:3

    Topics: Coronary Angiography; Coronary Disease; Coronary Vessels; Humans; Injections, Intra-Arterial; Molsid

1987
[The importance of Lopion (molsidomine) in the therapy of myocardial ischemia and angina pectoris].
    Medicinski pregled, 1987, Volume: 40, Issue:1-2

    Topics: Angina Pectoris; Coronary Disease; Exercise Test; Humans; Middle Aged; Molsidomine

1987
Acute and chronic effects of molsidomine on pulmonary artery pressure and work capacity in patients with coronary heart disease.
    European heart journal, 1987, Volume: 8, Issue:8

    Topics: Adult; Blood Pressure; Coronary Disease; Drug Tolerance; Exercise Test; Hemodynamics; Humans; Male;

1987
[We need molsidomine for complete prevention of ischemia. Interview with Prof. Rudolph on the therapy of coronary heart disease].
    Fortschritte der Medizin, 1986, Apr-03, Volume: 104, Issue:13

    Topics: Coronary Disease; Drug Therapy, Combination; Humans; Molsidomine; Oxadiazoles; Sydnones; Vasodilator

1986
Molsidomine prevents post-ischaemic ventricular fibrillation in dogs.
    British journal of pharmacology, 1986, Volume: 88, Issue:4

    Topics: Adenosine Diphosphate; Animals; Arrhythmias, Cardiac; Cardiac Output; Coronary Disease; Dogs; Electr

1986
[Biorhythm influence on the course of ischemic heart disease during combined treatment with molsidomine and anaprilin].
    Terapevticheskii arkhiv, 1986, Volume: 58, Issue:12

    Topics: Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Emergencies; Humans; Molsidomine; Peri

1986
Proceedings of the International Symposium on Molsidomine. November 5, 1983, Brussels, Belgium.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Coronary Disease; Heart Failure; Humans; Molsidomine; Oxadiazoles; Sydnones; Vasodilator Agents

1985
Pharmacokinetics of molsidomine in humans.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Animals; Biological Availability; Coronary Disease; Dogs; Half-Life; Humans; Kinetics; Molsidomine;

1985
Effects of molsidomine on regional contraction and global function of the left ventricle.
    American heart journal, 1985, Volume: 109, Issue:3 Pt 2

    Topics: Adult; Coronary Disease; Exercise Test; Female; Heart Ventricles; Humans; Male; Metoprolol; Middle A

1985
The effect of molsidomine on intramyocardial pressure and regional myocardial blood flow in the canine ischemic myocardium.
    Japanese circulation journal, 1985, Volume: 49, Issue:5

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Dogs; Heart; Kinetics; Molsidomine;

1985
Haemodynamic effects of molsidomine in patients with severe chronic coronary disease.
    European heart journal, 1985, Volume: 6, Issue:12

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Circulation; Coronary Disease; Electric Stimu

1985
Hemodynamic effects of molsidomine on weight sustaining isometric exercise in patients with ischemic heart disease.
    The Bulletin of Tokyo Medical and Dental University, 1985, Volume: 32, Issue:4

    Topics: Adult; Aged; Blood Pressure; Coronary Disease; Female; Heart Rate; Hemodynamics; Humans; Isometric C

1985
[Relation between therapeutic efficacy of antianginal preparations in patients with ischemic heart disease and their effect on the rheologic properties of blood].
    Kardiologiia, 1985, Volume: 25, Issue:9

    Topics: Adult; Amiodarone; Benzofurans; Blood Coagulation; Blood Viscosity; Coronary Disease; Erythrocyte Ag

1985