molsidomine has been researched along with Cholestasis in 1 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cholestasis and endotoxemia have been demonstrated to cause hepatocyte apoptosis through caspase-mediated pathways." | 5.32 | The nitric oxide donor molsidomine improves survival and reduces hepatocyte apoptosis in cholestasis and endotoxemia. ( Brems, JJ; Brown, KM; Ding, JW; Gamelli, RL; Hartman, GG; Moazzam, FN, 2003) |
| "Cholestasis and endotoxemia have been demonstrated to cause hepatocyte apoptosis through caspase-mediated pathways." | 1.32 | The nitric oxide donor molsidomine improves survival and reduces hepatocyte apoptosis in cholestasis and endotoxemia. ( Brems, JJ; Brown, KM; Ding, JW; Gamelli, RL; Hartman, GG; Moazzam, FN, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, KM | 1 |
| Brems, JJ | 1 |
| Moazzam, FN | 1 |
| Hartman, GG | 1 |
| Gamelli, RL | 1 |
| Ding, JW | 1 |
1 other study available for molsidomine and Cholestasis
| Article | Year |
|---|---|
The nitric oxide donor molsidomine improves survival and reduces hepatocyte apoptosis in cholestasis and endotoxemia.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cholestasis; Common Bile Duct; Endotoxemia; Hepatocytes; Li | 2003 |