Page last updated: 2024-10-31

molsidomine and Chemical and Drug Induced Liver Injury

molsidomine has been researched along with Chemical and Drug Induced Liver Injury in 5 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.

Research Excerpts

ExcerptRelevanceReference
"So, molsidomine was used as a NO donor in this study."1.32Protection against concanavalin A-induced hepatocyte apoptosis by molsidomine is time-dependent. ( Brems, JJ; Ding, JW; Gamelli, RL; Wang, K, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Samdanci, ET1
Huz, M1
Ozhan, O1
Tanbek, K1
Pamukcu, E1
Akatli, AN1
Parlakpinar, H1
Ding, JW1
Wang, K1
Brems, JJ1
Gamelli, RL2
Merino Ugarte, C1
Kumins, NH1
Hunt, J1
Filkins, JP1
Okamoto, T1
Masuda, Y1
Kawasaki, T1

Reviews

1 review available for molsidomine and Chemical and Drug Induced Liver Injury

ArticleYear
[Nitric oxide in gastroenterology].
    Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru, 1995, Volume: 15 Suppl 1

    Topics: Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Digestive System; Digestive System

1995

Other Studies

4 other studies available for molsidomine and Chemical and Drug Induced Liver Injury

ArticleYear
Cytoprotective effects of molsidomine against methotrexate-induced hepatotoxicity: an experimental rat study.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection

2019
Protection against concanavalin A-induced hepatocyte apoptosis by molsidomine is time-dependent.
    Journal of the American College of Surgeons, 2004, Volume: 198, Issue:1

    Topics: Alanine Transaminase; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Chemical and Dr

2004
Molsidomine increases endotoxic survival and decreases cytokine production.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytokines; Dose-Response Relationship, Drug; Endoto

1997
Prevention of concanavalin A-induced mice hepatitis by molsidomine.
    International journal of molecular medicine, 2001, Volume: 7, Issue:3

    Topics: Alanine Transaminase; Animals; Antibodies; Chemical and Drug Induced Liver Injury; Concanavalin A; D

2001