molsidomine has been researched along with Cardiac Output, Low in 3 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prolonged administration of nitroglycerin and its derivatives results in pharmacodynamic tolerance: although the dosage of these drugs is kept at the same level, their therapeutic effects decrease in amplitude." | 1.27 | [Comparative course of maintenance of the effects of nitrite derivatives and molsidomine after prolonged administration]. ( Degeorges, M; Weber, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mareev, VIu | 1 |
| Sazonova, LN | 1 |
| Grigor'iants, RA | 1 |
| Lobova, NM | 1 |
| Irani, RM | 1 |
| Himbert, D | 1 |
| Spreux-Varoquaux, O | 1 |
| Jaeger, P | 1 |
| Himbert, C | 1 |
| Cohen-Solal, A | 1 |
| Advenier, C | 1 |
| Gourgon, R | 1 |
| Weber, S | 1 |
| Degeorges, M | 1 |
1 trial available for molsidomine and Cardiac Output, Low
| Article | Year |
|---|---|
[Acute hemodynamic effects of SIN-1 and isosorbide dinitrate in stable left ventricular failure: a comparative double-blind, cross-over study].
Topics: Adult; Aged; Aged, 80 and over; Cardiac Output, Low; Double-Blind Method; Female; Hemodynamics; Huma | 1992 |
2 other studies available for molsidomine and Cardiac Output, Low
| Article | Year |
|---|---|
[Use of the vasodilator molsidomin in the treatment of chronic cardiac insufficiency].
Topics: Administration, Oral; Cardiac Output, Low; Chronic Disease; Female; Hemodynamics; Humans; Injections | 1983 |
[Comparative course of maintenance of the effects of nitrite derivatives and molsidomine after prolonged administration].
Topics: Administration, Sublingual; Angina Pectoris; Cardiac Output, Low; Dose-Response Relationship, Drug; | 1988 |