Page last updated: 2024-10-31

molsidomine and Cardiac Diseases

molsidomine has been researched along with Cardiac Diseases in 5 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"Molsidomine was unable to significantly attenuate mortality, development of heart failure and morphological damage induced by DAU."5.43Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings? ( Adamcová, M; Bureš, J; Hroch, M; Jansová, H; Jirkovská-Vávrová, A; Jirkovský, E; Kovaříková, P; Lenčová-Popelová, O; Mazurová, Y; Pokorná, Z; Reimerová, P; Šimůnek, T; Štěrba, M; Vostatková, L, 2016)
"Molsidomine was unable to significantly attenuate mortality, development of heart failure and morphological damage induced by DAU."1.43Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings? ( Adamcová, M; Bureš, J; Hroch, M; Jansová, H; Jirkovská-Vávrová, A; Jirkovský, E; Kovaříková, P; Lenčová-Popelová, O; Mazurová, Y; Pokorná, Z; Reimerová, P; Šimůnek, T; Štěrba, M; Vostatková, L, 2016)
"Molsidomine was administered sub-lingually to two groups of five patients."1.27[Acute hemodynamic effects of molsidomine in man]. ( Boutarin, J; Ferrini, M; Ritz, B; Tartulier, M, 1983)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lenčová-Popelová, O1
Jansová, H1
Jirkovský, E1
Bureš, J1
Jirkovská-Vávrová, A1
Mazurová, Y1
Reimerová, P1
Vostatková, L1
Adamcová, M1
Hroch, M1
Pokorná, Z1
Kovaříková, P1
Šimůnek, T1
Štěrba, M1
Cao, Z1
Li, Y1
Tartulier, M1
Ferrini, M1
Boutarin, J1
Ritz, B1
Arnal, JF1
Galinier, M1
Mazerolles, M1
Rami, J1
Besombes, JP1
Fauvel, JM1
Bounhoure, JP1
Gaál, J1
Vértesi, C1
Knopf, E1
Körmöczy, PS1

Trials

1 trial available for molsidomine and Cardiac Diseases

ArticleYear
Nasal nitric oxide concentration is decreased in heart failure patients receiving nitrates.
    Fundamental & clinical pharmacology, 1998, Volume: 12, Issue:1

    Topics: Adult; Aged; Female; Heart Diseases; Humans; Male; Middle Aged; Molsidomine; Nasal Cavity; Nitrates;

1998

Other Studies

4 other studies available for molsidomine and Cardiac Diseases

ArticleYear
Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?
    Toxicology, 2016, Nov-30, Volume: 372

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Cardiotonic Agents; Cardiotoxicity; Cell Line,

2016
Potent inhibition of peroxynitrite-induced DNA strand breakage by ethanol: possible implications for ethanol-mediated cardiovascular protection.
    Pharmacological research, 2004, Volume: 50, Issue:1

    Topics: Bacteriophage phi X 174; Bicarbonates; Central Nervous System Depressants; DNA Damage; DNA, Viral; E

2004
[Acute hemodynamic effects of molsidomine in man].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:8

    Topics: Adult; Heart; Heart Diseases; Hemodynamics; Humans; Middle Aged; Molsidomine; Myocardial Contraction

1983
Comparison of the cardioprotective effect of nitroglycerin, molsidomine and SIN-1 in rats with cardiac hypoxia.
    Acta physiologica Hungarica, 1990, Volume: 75 Suppl

    Topics: Animals; Antihypertensive Agents; Heart Diseases; Hypoxia; Molsidomine; Nitroglycerin; Rats

1990