molsidomine has been researched along with Bronchial Hyperreactivity in 3 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Airway inflammation was monitored by bronchoalveolar lavage, three and seven days after administration." | 1.31 | Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness. ( Folkerts, G; Habernickel, J; Muijsers, RB; Nijkamp, FP; Postma, DS; van der Veeken, A, 2002) |
| "Pretreatment with phosphoramidon, an NEP inhibitor, also enhanced SP- and ET-1-induced bronchoconstriction." | 1.30 | Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase. ( Hirata, K; Kanazawa, H; Yoshikawa, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strapkova, A | 1 |
| Antosova, M | 1 |
| Nosalova, G | 1 |
| Kanazawa, H | 1 |
| Hirata, K | 1 |
| Yoshikawa, J | 1 |
| Muijsers, RB | 1 |
| van der Veeken, A | 1 |
| Habernickel, J | 1 |
| Folkerts, G | 1 |
| Postma, DS | 1 |
| Nijkamp, FP | 1 |
3 other studies available for molsidomine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Interaction between nitric oxide and prostanoids in the respiratory system.
Topics: Animals; Bronchial Hyperreactivity; Cyclooxygenase Inhibitors; Diclofenac; Guinea Pigs; In Vitro Tec | 2006 |
Administration of SIN-1 induces guinea pig airway hyperresponsiveness through inactivation of airway neutral endopeptidase.
Topics: Animals; Bronchial Hyperreactivity; Bronchoconstriction; Endothelin-1; Enzyme Activation; Glycopepti | 1999 |
Intra-luminal exposure of murine airways to peroxynitrite causes inflammation but not hyperresponsiveness.
Topics: Acetylcholine; Animals; Bronchi; Bronchial Hyperreactivity; Inflammation; Male; Methacholine Chlorid | 2002 |