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molsidomine and Body Weight

molsidomine has been researched along with Body Weight in 12 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"The present study addressed whether combined treatment with a phosphodiesterase type 5 inhibitor, sildenafil, and a nitric oxide donor, molsidomine, prevents development of pulmonary hypertension in chronic hypoxic rats."7.73Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats. ( Andersen, CU; Mulvany, MJ; Simonsen, U, 2005)
"NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis."7.72NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis. ( Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F, 2003)
"The present study addressed whether combined treatment with a phosphodiesterase type 5 inhibitor, sildenafil, and a nitric oxide donor, molsidomine, prevents development of pulmonary hypertension in chronic hypoxic rats."3.73Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats. ( Andersen, CU; Mulvany, MJ; Simonsen, U, 2005)
"NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis."3.72NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis. ( Daig, U; Krämer, S; Liefeldt, L; Martini, S; Neumayer, HH; Peters, H; Rückert, M; Schäper, F, 2003)
" We investigated whether a NO-donor, molsidomine, administered during NO synthase inhibition, could restore a normal pregnancy."3.69Lack of beneficial effects on the NO-donor, molsidomine, in the L-NAME-induced pre-eclamptic syndrome in pregnant rats. ( Boulanger, H; Es-Slami, S; Giudicelli, JF; Richer, C, 1996)
"Treatment with molsidomine (1 mg/kg/day) during cholesterol withdrawal did not affect plaque size but increased the thickness of the subendothelial macrophage-free layer consisting of SMC, and normalized both superoxide production and ecSOD mRNA expression."1.32Nitric oxide donor molsidomine favors features of atherosclerotic plaque stability during cholesterol lowering in rabbits. ( Bult, H; De Cleen, DM; De Meyer, GR; Herman, AG; Knaapen, MW; Kockx, MM; Martinet, W, 2003)
"We studied the effects of long-term administration of molsidomine and pentaerythrityl tetranitrate (PETN) on the cardiovascular system of spontaneously hypertensive rats (SHR)."1.32Long-term effect of molsidomine and pentaerythrityl tetranitrate on cardiovascular system of spontaneously hypertensive rats. ( Fáberová, V; Kristek, F; Varga, I, 2003)
"4."1.32The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats. ( de Dam, MY; Elmedal, B; Mulvany, MJ; Simonsen, U, 2004)
" Here, we evaluated whether chronic administration of an NO donor, molsidomine, controlled systemic blood pressure and renal disease progression and prolonged survival in rats with renal mass reduction (RMR)."1.30Renoprotection by nitric oxide donor and lisinopril in the remnant kidney model. ( Benedetti, G; Benigni, A; Bruzzi, I; Corna, D; Noris, M; Remuzzi, G; Todeschini, M; Zoja, C, 1999)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's7 (58.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Meyer, GR2
Kockx, MM1
Knaapen, MW1
Martinet, W1
De Cleen, DM1
Bult, H2
Herman, AG2
Peters, H1
Daig, U1
Martini, S1
Rückert, M1
Schäper, F1
Liefeldt, L1
Krämer, S1
Neumayer, HH1
Cukiernik, M1
Mukherjee, S1
Downey, D1
Chakabarti, S1
Kristek, F1
Fáberová, V1
Varga, I1
Elmedal, B1
de Dam, MY1
Mulvany, MJ2
Simonsen, U2
Andersen, CU1
Joly, GA1
Schini, VB1
Hughes, H1
Vanhoutte, PM1
Böger, RH1
Bode-Böger, SM1
Gerecke, U1
Frölich, JC1
Richer, C1
Boulanger, H1
Es-Slami, S1
Giudicelli, JF1
Benigni, A1
Zoja, C1
Noris, M1
Corna, D1
Benedetti, G1
Bruzzi, I1
Todeschini, M1
Remuzzi, G1
Attia, DM1
Ni, ZN1
Boer, P1
Attia, MA1
Goldschmeding, R1
Koomans, HA1
Vaziri, ND1
Joles, JA1

Other Studies

12 other studies available for molsidomine and Body Weight

ArticleYear
Nitric oxide donor molsidomine favors features of atherosclerotic plaque stability during cholesterol lowering in rabbits.
    Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:6

    Topics: Acetonitriles; Animals; Aorta; Apoptosis; Arteriosclerosis; Body Weight; Cholesterol; Cholesterol, D

2003
NO mediates antifibrotic actions of L-arginine supplementation following induction of anti-thy1 glomerulonephritis.
    Kidney international, 2003, Volume: 64, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Body Weight; Enzyme Inhibitors; Fibronectins; Fibrosis; Gene Expr

2003
Heme oxygenase in the retina in diabetes.
    Current eye research, 2003, Volume: 27, Issue:5

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothel

2003
Long-term effect of molsidomine and pentaerythrityl tetranitrate on cardiovascular system of spontaneously hypertensive rats.
    Physiological research, 2003, Volume: 52, Issue:6

    Topics: Animals; Aorta; Aorta, Thoracic; Blood Platelets; Blood Pressure; Body Weight; Cardiovascular System

2003
The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats.
    British journal of pharmacology, 2004, Volume: 141, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Administration, O

2004
Lack of synergistic effect of molsidomine and sildenafil on development of pulmonary hypertension in chronic hypoxic rats.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Acetylcholine; Actins; Animals; Atrial Natriuretic Factor; Body Weight; Dose-Response Relationship,

2005
Influence of chronic treatment with a nitric oxide donor on fatty streak development and reactivity of the rabbit aorta.
    British journal of pharmacology, 1995, Volume: 114, Issue:7

    Topics: Acetylcholine; Animals; Aorta; Aortic Diseases; Arteriosclerosis; Body Weight; Cholesterol; Dietary

1995
Potentiation of the hyporeactivity induced by in vivo endothelial injury in the rat carotid artery by chronic treatment with fish oil.
    British journal of pharmacology, 1995, Volume: 115, Issue:2

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Body Weight; Carotid Arteries; Carotid Arte

1995
Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats.
    Cardiovascular research, 1994, Volume: 28, Issue:4

    Topics: Animals; Arginine; Blood Pressure; Body Weight; Cholesterol; Chromatography, Gas; Cyclic GMP; Heart;

1994
Lack of beneficial effects on the NO-donor, molsidomine, in the L-NAME-induced pre-eclamptic syndrome in pregnant rats.
    British journal of pharmacology, 1996, Volume: 119, Issue:8

    Topics: Animals; Blood Pressure; Body Weight; Enzyme Inhibitors; Female; Fetus; Heart; Heart Rate; Molsidomi

1996
Renoprotection by nitric oxide donor and lisinopril in the remnant kidney model.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Creatinine; Disease

1999
Proteinuria is preceded by decreased nitric oxide synthesis and prevented by a NO donor in cholesterol-fed rats.
    Kidney international, 2002, Volume: 61, Issue:5

    Topics: Animals; Blood Pressure; Body Weight; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Chol

2002