molsidomine has been researched along with Blood Pressure, Low in 6 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Discrepancy was found between enhanced hypotension and attenuated relaxation of conduit arteries in response to acetylcholine (ACh) and bradykinin (BK) in nitric oxide (NO)-deficient hypertension." | 7.73 | Acetylcholine and bradykinin enhance hypotension and affect the function of remodeled conduit arteries in SHR and SHR treated with nitric oxide donors. ( Cacányiová, S; Cebová, M; Gerová, M; Kristek, F, 2005) |
| "Amitriptyline intoxication was induced by the continuous infusion of amitriptyline 0." | 5.31 | The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats. ( Arkan, F; Aygoren, O; Guven, H; Kalkan, S; Kurt, S; Murat, N; Tuncok, Y, 2002) |
| "Discrepancy was found between enhanced hypotension and attenuated relaxation of conduit arteries in response to acetylcholine (ACh) and bradykinin (BK) in nitric oxide (NO)-deficient hypertension." | 3.73 | Acetylcholine and bradykinin enhance hypotension and affect the function of remodeled conduit arteries in SHR and SHR treated with nitric oxide donors. ( Cacányiová, S; Cebová, M; Gerová, M; Kristek, F, 2005) |
| "Amitriptyline intoxication was induced by the continuous infusion of amitriptyline 0." | 1.31 | The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats. ( Arkan, F; Aygoren, O; Guven, H; Kalkan, S; Kurt, S; Murat, N; Tuncok, Y, 2002) |
| "We sought to investigate whether linsidomine chlorhydrate (SIN1, the active metabolite of molsidomine and a nitric oxide donor) has a toxic effect when used chronically for the treatment of impotence." | 1.29 | Intracavernous injection of linsidomine chlorhydrate in monkeys: lack of toxic effect with long-term use. ( Brock, GB; Lue, TF; Martinez-Piñeiro, L; von Heyden, B, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tuncok, Y | 1 |
| Kalkan, S | 1 |
| Murat, N | 1 |
| Arkan, F | 1 |
| Guven, H | 1 |
| Aygoren, O | 1 |
| Kurt, S | 1 |
| Takakura, K | 1 |
| Xiaohong, W | 1 |
| Takeuchi, K | 1 |
| Yasuda, Y | 1 |
| Fukuda, S | 1 |
| Gerová, M | 1 |
| Kristek, F | 1 |
| Cacányiová, S | 1 |
| Cebová, M | 1 |
| Kovách, AG | 1 |
| Lohinai, Z | 1 |
| Marczis, J | 1 |
| Balla, I | 1 |
| Dawson, TM | 1 |
| Snyder, SH | 1 |
| Teranishi, Y | 1 |
| Iriuchijima, J | 1 |
| von Heyden, B | 1 |
| Brock, GB | 1 |
| Martinez-Piñeiro, L | 1 |
| Lue, TF | 1 |
6 other studies available for molsidomine and Blood Pressure, Low
| Article | Year |
|---|---|
The effect of the nitric oxide synthesis inhibitor L-NAME on amitriptyline-induced hypotension in rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Drug Interactions; Enzyme | 2002 |
Deactivation of norepinephrine by peroxynitrite as a new pathogenesis in the hypotension of septic shock.
Topics: Anesthesia; Animals; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Hydrogen-Ion Concentrati | 2003 |
Acetylcholine and bradykinin enhance hypotension and affect the function of remodeled conduit arteries in SHR and SHR treated with nitric oxide donors.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Carotid Arteries; Hypotension; Iliac Artery; Mal | 2005 |
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
Topics: Acetylcholine; Adenosine Triphosphate; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Bl | 1994 |
Hindquarter vascular resistance as compensator for hypotension in conscious rats.
Topics: Animals; Consciousness; Ganglia; Hexamethonium; Hindlimb; Hypotension; Male; Mesenteric Artery, Supe | 1994 |
Intracavernous injection of linsidomine chlorhydrate in monkeys: lack of toxic effect with long-term use.
Topics: Animals; Blood Pressure; Hypotension; Macaca fascicularis; Macaca nemestrina; Male; Molsidomine; Pen | 1996 |