molsidomine has been researched along with Atherosclerosis in 3 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Atherosclerosis: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The observation that 3-nitrotyrosine-containing proteins colocalize with markers of ER stress within early atherosclerotic lesions suggests that peroxynitrite contributes to atherogenesis through a mechanism involving ER stress." | 3.73 | Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. ( Austin, RC; Dickhout, JG; Hossain, GS; Lhoták, S; Pozza, LM; Zhou, J, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickhout, JG | 1 |
| Hossain, GS | 1 |
| Pozza, LM | 1 |
| Zhou, J | 1 |
| Lhoták, S | 1 |
| Austin, RC | 1 |
| Torres-Rasgado, E | 1 |
| Fouret, G | 1 |
| Carbonneau, MA | 1 |
| Leger, CL | 1 |
| Martinet, W | 1 |
| Croons, V | 1 |
| Timmermans, JP | 1 |
| Herman, AG | 1 |
| De Meyer, GR | 1 |
3 other studies available for molsidomine and Atherosclerosis
| Article | Year |
|---|---|
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis.
Topics: Animals; Aorta; Apolipoproteins E; Apoptosis; Atherosclerosis; Calcium; Cells, Cultured; Endoplasmic | 2005 |
Peroxynitrite mild nitration of albumin and LDL-albumin complex naturally present in plasma and tyrosine nitration rate-albumin impairs LDL nitration.
Topics: Antioxidants; Atherosclerosis; Humans; Lipoproteins, LDL; Molsidomine; Nitric Oxide Donors; Nitrogen | 2007 |
Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Atherosclerosis; Caspase 3; Cell Line; Cell Survival; Cells, Cultured; Endoplasm | 2007 |