molsidomine has been researched along with Arrhythmias, Cardiac in 7 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of our research was to compare molsidomine, SIN-1, SIN-1A, and lidocaine influence on arrhythmias and hemodynamic parameters in 2 experimental models in rats." | 3.85 | New approach to molsidomine active metabolites coming from the results of 2 models of experimental cardiology. ( Krzemiński, TF; Mitręga, KA; Porc, M; Żorniak, M, 2017) |
| "Allopurinol-treated hearts had significantly decreased nerve growth factor expression, which was substantially increased after coadministration of 3-morpholinosydnonimine." | 1.37 | Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts. ( Chen, CC; Hsu, YJ; Lee, TM, 2011) |
| "Molsidomine protected the treated animals from early (10 min) post-ischaemic ventricular fibrillation (0 of 20 vs 6 of 20, P = 0." | 1.27 | Molsidomine prevents post-ischaemic ventricular fibrillation in dogs. ( Cano, JP; Guillen, JC; Jouve, R; Langlet, F; Puddu, PE; Rolland, PH; Serradimigni, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shan, Y | 1 |
| Wang, D | 1 |
| Li, R | 1 |
| Huang, C | 1 |
| Żorniak, M | 1 |
| Mitręga, KA | 1 |
| Porc, M | 1 |
| Krzemiński, TF | 1 |
| Lee, TM | 1 |
| Chen, CC | 1 |
| Hsu, YJ | 1 |
| Kuz'ko, NV | 1 |
| Barnes, CS | 1 |
| Coker, SJ | 2 |
| Aitchison, KA | 1 |
| Cano, JP | 1 |
| Guillen, JC | 1 |
| Jouve, R | 1 |
| Langlet, F | 1 |
| Puddu, PE | 1 |
| Rolland, PH | 1 |
| Serradimigni, A | 1 |
7 other studies available for molsidomine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Molsidomine Attenuates Ventricular Electrical Remodeling and Arrhythmogenesis in Rats With Chronic β-Adrenergic Receptor Activation Through the NO/cGMP/PKG Pathway.
Topics: Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dep | 2016 |
New approach to molsidomine active metabolites coming from the results of 2 models of experimental cardiology.
Topics: Animals; Anti-Asthmatic Agents; Arrhythmias, Cardiac; Creatine Kinase; Disease Models, Animal; Hemod | 2017 |
Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts.
Topics: Acetophenones; Allopurinol; Animals; Arrhythmias, Cardiac; Coronary Vessels; Ethidium; Male; Molsido | 2011 |
[Treatment with sidnonimine derivatives of chronic ischemic heart disease patients].
Topics: Angina Pectoris; Arrhythmias, Cardiac; Chronic Disease; Coronary Disease; Drug Evaluation; Female; H | 1984 |
Failure of nitric oxide donors to alter arrhythmias induced by acute myocardial ischaemia or reperfusion in anaesthetized rats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cyclic AMP; Cyclic GMP; Hemodynam | 1995 |
Potential interactions between iloprost and SIN-1 on platelet aggregation and myocardial infarct size in vivo.
Topics: Animals; Arrhythmias, Cardiac; Creatine Kinase; Drug Synergism; Electrocardiography; Hemodynamics; I | 1999 |
Molsidomine prevents post-ischaemic ventricular fibrillation in dogs.
Topics: Adenosine Diphosphate; Animals; Arrhythmias, Cardiac; Cardiac Output; Coronary Disease; Dogs; Electr | 1986 |