molsidomine has been researched along with Anesthesia in 9 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have recently reported that halothane (Hal) anesthesia attenuates the pulmonary vasodilator responses to both bradykinin (BK) and sodium nitroprusside (SNP) compared with responses measured in the conscious state." | 7.69 | Endothelium-dependent pulmonary vasodilation is selectively attenuated during isoflurane anesthesia. ( Fujiwara, Y; Gambone, LM; Murray, PA, 1997) |
| "We have recently reported that halothane (Hal) anesthesia attenuates the pulmonary vasodilator responses to both bradykinin (BK) and sodium nitroprusside (SNP) compared with responses measured in the conscious state." | 3.69 | Endothelium-dependent pulmonary vasodilation is selectively attenuated during isoflurane anesthesia. ( Fujiwara, Y; Gambone, LM; Murray, PA, 1997) |
| "Pretreatment with tamoxifen (TAM) 10 micromol/L, an inhibitor of estrogen receptor, did not block the effect of E2 on CBA." | 1.31 | 17 beta-Estradiol inhibits carotid sinus baroreceptor activity in anesthetized male rats. ( Fan, ZZ; He, RR; Wang, S, 2001) |
| "When nitroglycerin (NTG) was used as the reference compound at 1." | 1.29 | Effect of ITF 296 on total effective vascular compliance in the anesthetized dog under autonomic blockade. ( Bassenge, E; Cereda, R; Fink, B, 1995) |
| "Molsidomine treatment 15 min prior to repeated intracoronary LTD4 application attenuated vasoconstrictor response to LTD4 and the subsequent elevation in total coronary vascular resistance." | 1.27 | Molsidomine on cardiovascular leukotriene D4 actions. ( Abram, TS; Fiedler, VB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takakura, K | 1 |
| Xiaohong, W | 1 |
| Takeuchi, K | 1 |
| Yasuda, Y | 1 |
| Fukuda, S | 1 |
| Fiedler, VB | 3 |
| Göbel, H | 1 |
| Nitz, RE | 1 |
| Buchheim, S | 1 |
| Scholtholt, J | 1 |
| Barnes, CS | 1 |
| Coker, SJ | 1 |
| Fink, B | 1 |
| Cereda, R | 1 |
| Bassenge, E | 1 |
| Gambone, LM | 1 |
| Fujiwara, Y | 1 |
| Murray, PA | 1 |
| Arnolda, LF | 1 |
| McKitrick, DJ | 1 |
| Llewellyn-Smith, IJ | 1 |
| Minson, JB | 1 |
| Wang, S | 1 |
| Fan, ZZ | 1 |
| He, RR | 1 |
| Abram, TS | 1 |
9 other studies available for molsidomine and Anesthesia
| Article | Year |
|---|---|
Deactivation of norepinephrine by peroxynitrite as a new pathogenesis in the hypotension of septic shock.
Topics: Anesthesia; Animals; Aorta, Thoracic; Binding, Competitive; Blood Pressure; Hydrogen-Ion Concentrati | 2003 |
Effects of dihydroergotamine on hemodynamic molsidomine actions in anesthetized dogs.
Topics: Anesthesia; Animals; Cardiac Output; Cardiovascular Diseases; Dihydroergotamine; Dogs; Drug Interact | 1984 |
The effects of molsidomine on intracranial pressure in anaesthetized dogs.
Topics: Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Female; Intracranial Pressure; Male; Mo | 1982 |
Failure of nitric oxide donors to alter arrhythmias induced by acute myocardial ischaemia or reperfusion in anaesthetized rats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cyclic AMP; Cyclic GMP; Hemodynam | 1995 |
Effect of ITF 296 on total effective vascular compliance in the anesthetized dog under autonomic blockade.
Topics: Anesthesia; Animals; Autonomic Nerve Block; Benzoxazines; Blood Pressure; Dogs; Female; Hemodynamics | 1995 |
Endothelium-dependent pulmonary vasodilation is selectively attenuated during isoflurane anesthesia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Anesthesia; Animals; Blood Press | 1997 |
Nitric oxide limits pressor responses to sympathetic activation in rat spinal cord.
Topics: Anesthesia; Animals; Arginine; Calcium; Enzyme Activation; Enzyme Inhibitors; Male; Molsidomine; N-M | 2000 |
17 beta-Estradiol inhibits carotid sinus baroreceptor activity in anesthetized male rats.
Topics: Anesthesia; Animals; Carotid Sinus; Estradiol; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nit | 2001 |
Molsidomine on cardiovascular leukotriene D4 actions.
Topics: Anesthesia; Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Hemodynamics; Male; Molsido | 1985 |