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molsidomine and Anaphylactic Reaction

molsidomine has been researched along with Anaphylactic Reaction in 2 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"The modulating effects of exogenous and endogenous nitric oxide (NO) on the cardiac anaphylactic reaction and eicosanoid release were investigated in isolated perfused sensitized guinea-pig hearts using 3-morpholinosydnonimine (SIN-1), the active metabolite of molsidomine, as NO-donor and NG-nitro-L-arginine (NNA) as an inhibitor of NO biosynthesis."3.68Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-L-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts. ( Dembinska-Kiéc, A; Pallapies, D; Peskar, BA; Simmet, T; Thelen, KI, 1992)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thelen, KI1
Dembinska-Kiéc, A2
Pallapies, D2
Simmet, T2
Peskar, BA2
Thelen, K1

Other Studies

2 other studies available for molsidomine and Anaphylactic Reaction

ArticleYear
Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-L-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Anaphylaxis; Animals; Antihypertensive Agents; Arginine; Coronary Circ

1992
Effect of 3-morpholinosydnonimine (SIN-1), NG-nitro-L-arginine (NNA) and NG-monomethyl-L-arginine (NMMA) on isolated anaphylactic guinea-pig hearts.
    Agents and actions. Supplements, 1992, Volume: 37

    Topics: Anaphylaxis; Animals; Arginine; Coronary Circulation; Eicosanoids; Guinea Pigs; Heart; Heart Rate; I

1992