molsidomine has been researched along with Alzheimer Disease in 6 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramos-Fernández, E | 1 |
| Tajes, M | 1 |
| Palomer, E | 1 |
| Ill-Raga, G | 1 |
| Bosch-Morató, M | 1 |
| Guivernau, B | 1 |
| Román-Dégano, I | 1 |
| Eraso-Pichot, A | 1 |
| Alcolea, D | 1 |
| Fortea, J | 1 |
| Nuñez, L | 1 |
| Paez, A | 1 |
| Alameda, F | 1 |
| Fernández-Busquets, X | 1 |
| Lleó, A | 1 |
| Elosúa, R | 1 |
| Boada, M | 1 |
| Valverde, MA | 1 |
| Muñoz, FJ | 1 |
| Buizza, L | 1 |
| Cenini, G | 1 |
| Lanni, C | 1 |
| Ferrari-Toninelli, G | 1 |
| Prandelli, C | 1 |
| Govoni, S | 1 |
| Buoso, E | 1 |
| Racchi, M | 1 |
| Barcikowska, M | 1 |
| Styczynska, M | 1 |
| Szybinska, A | 1 |
| Butterfield, DA | 1 |
| Memo, M | 1 |
| Uberti, D | 1 |
| Huang, HM | 1 |
| Zhang, H | 1 |
| Ou, HC | 1 |
| Chen, HL | 1 |
| Gibson, GE | 1 |
| Bastianetto, S | 1 |
| Zheng, WH | 1 |
| Quirion, R | 1 |
| Jonnala, RR | 1 |
| Buccafusco, JJ | 1 |
| Williamson, KS | 1 |
| Gabbita, SP | 1 |
| Mou, S | 1 |
| West, M | 1 |
| Pye, QN | 1 |
| Markesbery, WR | 1 |
| Cooney, RV | 1 |
| Grammas, P | 1 |
| Reimann-Philipp, U | 1 |
| Floyd, RA | 1 |
| Hensley, K | 1 |
6 other studies available for molsidomine and Alzheimer Disease
| Article | Year |
|---|---|
Posttranslational nitro-glycative modifications of albumin in Alzheimer's disease: implications in cytotoxicity and amyloid-β peptide aggregation.
Topics: Aged; Albumins; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cells, Cultured; Dose-Response Rela | 2014 |
Conformational altered p53 as an early marker of oxidative stress in Alzheimer's disease.
Topics: Adult; Age of Onset; Alzheimer Disease; Biomarkers; Case-Control Studies; Demography; Female; Glutat | 2012 |
alpha-keto-beta-methyl-n-valeric acid diminishes reactive oxygen species and alters endoplasmic reticulum Ca(2+) stores.
Topics: Alzheimer Disease; Animals; Apoptosis; Calcium; Cell Line; Endoplasmic Reticulum; Fluoresceins; Free | 2004 |
The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C.
Topics: Alkaloids; Alzheimer Disease; Animals; Antioxidants; Azoles; Benzophenanthridines; Brain Ischemia; C | 2000 |
Inhibition of nerve growth factor signaling by peroxynitrite.
Topics: Acetylcholine; Alzheimer Disease; Animals; Brain; Cell Survival; Dose-Response Relationship, Drug; H | 2001 |
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Brain; Female; gamma-Tocopherol; Humans; K | 2002 |