molsidomine has been researched along with Alloxan Diabetes in 7 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results highlight the rationale behind the repositioning of molsidomine therapy for the management of diabetic erectile dysfunction." | 7.88 | Repositioning of molsidomine for its efficacy in diabetes induced erectile dysfunction in rats: In silico, in vitro and in vivo approach. ( Minaz, N; Pathak, L; Razdan, R, 2018) |
| "The results highlight the rationale behind the repositioning of molsidomine therapy for the management of diabetic erectile dysfunction." | 3.88 | Repositioning of molsidomine for its efficacy in diabetes induced erectile dysfunction in rats: In silico, in vitro and in vivo approach. ( Minaz, N; Pathak, L; Razdan, R, 2018) |
| "• To investigate whether sustained long-term separate treatments of diabetic inducible nitric oxide synthase knockout (iNOSKo) mice with allopurinol, an antioxidant inhibiting xanthine oxidoreductase, decorin, a transforming growth factor-β1 (TGFβ1) -binding antagonist, and molsidomine, a long-life nitric oxide donor, prevent the processes of diabetes-induced cavernosal fibrosis." | 3.78 | Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-β1 therapies in inducible nitric oxide synthase-deficient mice. ( Ferrini, MG; Gonzalez-Cadavid, NF; Moon, J; Rajfer, J; Rivera, S, 2012) |
| "Treatment with molsidomine significantly improved motor coordination, paw withdrawal threshold, mechanical threshold, and nerve conduction velocity." | 1.62 | Molsidomine ameliorates diabetic peripheral neuropathy complications in Wistar rats. ( Minaz, N; Nayak B, P; Pasha, K, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Nayak B, P | 1 |
| Minaz, N | 2 |
| Pasha, K | 1 |
| Razdan, R | 1 |
| Pathak, L | 1 |
| Ferrini, MG | 1 |
| Moon, J | 1 |
| Rivera, S | 1 |
| Rajfer, J | 1 |
| Gonzalez-Cadavid, NF | 1 |
| Witte, MB | 1 |
| Kiyama, T | 1 |
| Barbul, A | 1 |
| Cukiernik, M | 1 |
| Mukherjee, S | 1 |
| Downey, D | 1 |
| Chakabarti, S | 1 |
| Tasatargil, A | 1 |
| Sadan, G | 1 |
| González, E | 1 |
| Jawerbaum, A | 1 |
| Sinner, D | 1 |
| Pustovrh, C | 1 |
| Xaus, C | 1 |
| Peralta, C | 1 |
| Gómez, G | 1 |
| Roselló-Catafau, J | 1 |
| Gelpi, E | 1 |
| Gimeno, M | 1 |
7 other studies available for molsidomine and Alloxan Diabetes
| Article | Year |
|---|---|
Molsidomine ameliorates diabetic peripheral neuropathy complications in Wistar rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Molsidomine; Oxidative Stress | 2021 |
Repositioning of molsidomine for its efficacy in diabetes induced erectile dysfunction in rats: In silico, in vitro and in vivo approach.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Diabetes Mellitus, Experimental; Drug Repositioning | 2018 |
Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-β1 therapies in inducible nitric oxide synthase-deficient mice.
Topics: Allopurinol; Animals; Antioxidants; Apoptosis; Decorin; Diabetes Mellitus, Experimental; Enzyme Inhi | 2012 |
Nitric oxide enhances experimental wound healing in diabetes.
Topics: Animals; Blotting, Northern; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimen | 2002 |
Heme oxygenase in the retina in diabetes.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothel | 2003 |
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; D | 2004 |
Evolution of streptozotocin-pancreatic damage in the rat: modulatory effect of endothelins on the nitridergic and prostanoid pathway.
Topics: Animals; Arachidonic Acid; Diabetes Mellitus, Experimental; Dinoprost; Dinoprostone; Endothelin-1; E | 1999 |