molsidomine has been researched along with Allergic Encephalomyelitis in 5 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Uric acid (UA) is a purine metabolite that selectively inhibits peroxynitrite-mediated reactions implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative diseases." | 7.71 | Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors. ( Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV, 2002) |
| "Molsidomine (Mol) is a drug used for the treatment of coronary artery disease." | 5.32 | Molsidomine ameliorates experimental allergic encephalomyelitis in Lewis rats. ( Choi, BM; Chung, HT; Jang, SI; Jung, S; Kwak, HJ; Oh, GS; Pae, HO, 2003) |
| "Uric acid (UA) is a purine metabolite that selectively inhibits peroxynitrite-mediated reactions implicated in the pathogenesis of multiple sclerosis (MS) and other neurodegenerative diseases." | 3.71 | Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors. ( Hooper, DC; Kean, RB; Koprowski, H; Mikheeva, T; Scott, GS; Spitsin, SV, 2002) |
| "Molsidomine (Mol) is a drug used for the treatment of coronary artery disease." | 1.32 | Molsidomine ameliorates experimental allergic encephalomyelitis in Lewis rats. ( Choi, BM; Chung, HT; Jang, SI; Jung, S; Kwak, HJ; Oh, GS; Pae, HO, 2003) |
| "The role of NO in the pathogenesis of experimental allergic encephalomyelitis (EAE) is controversial." | 1.31 | SIN-1, a nitric oxide donor, ameliorates experimental allergic encephalomyelitis in Lewis rats in the incipient phase: the importance of the time window. ( Link, H; Xiao, BG; Xu, LY; Yang, JS, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spitsin, SV | 2 |
| Scott, GS | 2 |
| Mikheeva, T | 2 |
| Zborek, A | 1 |
| Kean, RB | 2 |
| Brimer, CM | 1 |
| Koprowski, H | 2 |
| Hooper, DC | 2 |
| Kwak, HJ | 1 |
| Pae, HO | 1 |
| Oh, GS | 1 |
| Choi, BM | 1 |
| Jang, SI | 1 |
| Jung, S | 1 |
| Chung, HT | 1 |
| van der Veen, RC | 1 |
| Roberts, LJ | 1 |
| Xu, LY | 1 |
| Yang, JS | 1 |
| Link, H | 1 |
| Xiao, BG | 1 |
5 other studies available for molsidomine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Comparison of uric acid and ascorbic acid in protection against EAE.
Topics: Albumins; Animals; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Cell Line; Encephalomyelitis, A | 2002 |
Therapeutic intervention in experimental allergic encephalomyelitis by administration of uric acid precursors.
Topics: Administration, Oral; Animals; Biotransformation; Chromatography, High Pressure Liquid; Drug Evaluat | 2002 |
Molsidomine ameliorates experimental allergic encephalomyelitis in Lewis rats.
Topics: Animals; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Immunohisto | 2003 |
Contrasting roles for nitric oxide and peroxynitrite in the peroxidation of myelin lipids.
Topics: Animals; Central Nervous System; Dinoprost; Encephalomyelitis, Autoimmune, Experimental; F2-Isoprost | 1999 |
SIN-1, a nitric oxide donor, ameliorates experimental allergic encephalomyelitis in Lewis rats in the incipient phase: the importance of the time window.
Topics: Adjuvants, Immunologic; Amino Acid Sequence; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antig | 2001 |