molsidomine has been researched along with Alcoholic Cirrhosis in 5 studies
Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2 [34-67] years) with cirrhosis of the liver of various aetiologies to determine whether molsidomine, which selectively reduces pre-load with-out the development of tolerance, effects portal and cardiac haemodynamics in liver cirrhosis and portal hypertension." | 7.68 | [The effect of molsidomine on portal and cardiac hemodynamics in liver cirrhosis]. ( Barmeyer, J; Hüppe, D; Jäger, D; May, B; Tromm, A; Tunn, S, 1991) |
| " The aim of the present study was to assess the hemodynamic effects of molsidomine, an antianginal agent, which does not induce tolerance and has little effect on arterial pressure in patients with normal liver, in 13 patients with alcoholic cirrhosis." | 7.68 | Hemodynamic evaluation of molsidomine: a vasodilator with antianginal properties in patients with alcoholic cirrhosis. ( Calés, P; Combis, JM; Desmorat, H; Monnin, JL; Pascal, JP; Vinel, JP, 1990) |
| "The pharmacokinetics of molsidomine were investigated in six healthy volunteers and in seven patients with alcoholic cirrhosis." | 5.07 | Pharmacokinetics of molsidomine and its active metabolite, linsidomine, in patients with liver cirrhosis. ( Advenier, C; Andrieu, J; Cordonnier, P; Doll, J; Dutot, C; Grandjean, N; Pays, M; Spreux-Varoquaux, O, 1991) |
| "2 [34-67] years) with cirrhosis of the liver of various aetiologies to determine whether molsidomine, which selectively reduces pre-load with-out the development of tolerance, effects portal and cardiac haemodynamics in liver cirrhosis and portal hypertension." | 3.68 | [The effect of molsidomine on portal and cardiac hemodynamics in liver cirrhosis]. ( Barmeyer, J; Hüppe, D; Jäger, D; May, B; Tromm, A; Tunn, S, 1991) |
| " The aim of the present study was to assess the hemodynamic effects of molsidomine, an antianginal agent, which does not induce tolerance and has little effect on arterial pressure in patients with normal liver, in 13 patients with alcoholic cirrhosis." | 3.68 | Hemodynamic evaluation of molsidomine: a vasodilator with antianginal properties in patients with alcoholic cirrhosis. ( Calés, P; Combis, JM; Desmorat, H; Monnin, JL; Pascal, JP; Vinel, JP, 1990) |
| "When molsidomine was added, TAV was further decreased (-17." | 2.67 | [Evaluation of the effects of molsidomine and propranolol-molsidomine combination on portal hemodynamics by pulsed Doppler ultrasound]. ( Blanc, F; Bruel, JM; Ciurana, AJ; Le Quellec, A; Michel, H; Monnin, JL; Pascal, JP; Taourel, P; Vinel, JP, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Combis, JM | 2 |
| Vinel, JP | 3 |
| Badia, P | 1 |
| Barange, K | 1 |
| Payen, JL | 1 |
| Combis, F | 1 |
| Desmorat, H | 2 |
| Pascal, JP | 3 |
| Monnin, JL | 2 |
| Le Quellec, A | 1 |
| Taourel, P | 1 |
| Bruel, JM | 1 |
| Blanc, F | 1 |
| Michel, H | 1 |
| Ciurana, AJ | 1 |
| Spreux-Varoquaux, O | 1 |
| Doll, J | 1 |
| Dutot, C | 1 |
| Grandjean, N | 1 |
| Cordonnier, P | 1 |
| Pays, M | 1 |
| Andrieu, J | 1 |
| Advenier, C | 1 |
| Hüppe, D | 1 |
| Jäger, D | 1 |
| Tromm, A | 1 |
| Tunn, S | 1 |
| Barmeyer, J | 1 |
| May, B | 1 |
| Calés, P | 1 |
2 trials available for molsidomine and Alcoholic Cirrhosis
| Article | Year |
|---|---|
[Evaluation of the effects of molsidomine and propranolol-molsidomine combination on portal hemodynamics by pulsed Doppler ultrasound].
Topics: Adult; Aged; Blood Flow Velocity; Drug Therapy, Combination; Female; Humans; Hypertension, Portal; L | 1992 |
Pharmacokinetics of molsidomine and its active metabolite, linsidomine, in patients with liver cirrhosis.
Topics: Adult; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Molsidomine; Reference Values | 1991 |
3 other studies available for molsidomine and Alcoholic Cirrhosis
| Article | Year |
|---|---|
Haemodynamic effects of molsidomine and propranolol in patients with cirrhosis.
Topics: Adrenergic beta-Antagonists; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; Humans | 1996 |
[The effect of molsidomine on portal and cardiac hemodynamics in liver cirrhosis].
Topics: Adult; Aged; Female; Heart; Hemodynamics; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Live | 1991 |
Hemodynamic evaluation of molsidomine: a vasodilator with antianginal properties in patients with alcoholic cirrhosis.
Topics: Hemodynamics; Humans; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Molsidomine; Splanchnic Circ | 1990 |