Page last updated: 2024-10-31

molsidomine and Age-Related Memory Disorders

molsidomine has been researched along with Age-Related Memory Disorders in 7 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
" In a first dose-response study, L-NAME, at 30 but not at 10 mg/kg impaired the animals' performance, whereas at 60 mg/kg, it induced side-effects."1.31Molsidomine attenuates N(omega)-nitro-L-argininemethylester-induced deficits in a memory task in the rat. ( Cella, SG; Muller, EE; Pitsikas, N; Rigamonti, AE, 2002)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Katsanou, L1
Fragkiadaki, E1
Kampouris, S1
Konstanta, A1
Vontzou, A1
Pitsikas, N5
Schaefer, ML1
Wang, M1
Perez, PJ1
Coca Peralta, W1
Xu, J1
Johns, RA1
Hernández-Melesio, MA1
Alcaraz-Zubeldia, M1
Jiménez-Capdeville, ME1
Martínez-Lazcano, JC1
Santoyo-Pérez, ME1
Quevedo-Corona, L1
Gerónimo-Olvera, C1
Sánchez-Mendoza, A1
Ríos, C1
Pérez-Severiano, F1
Boultadakis, A1
Liakos, P1
Rigamonti, AE2
Cella, SG2
Muller, EE2
Sakellaridis, N1

Other Studies

7 other studies available for molsidomine and Age-Related Memory Disorders

ArticleYear
The Nitric Oxide (NO) Donor Molsidomine Counteract Social Withdrawal and Cognition Deficits Induced by Blockade of the NMDA Receptor in the Rat.
    International journal of molecular sciences, 2023, Apr-06, Volume: 24, Issue:7

    Topics: Animals; Clozapine; Cognition; Cognitive Dysfunction; Ketamine; Memory Disorders; Molsidomine; Nitri

2023
Nitric Oxide Donor Prevents Neonatal Isoflurane-induced Impairments in Synaptic Plasticity and Memory.
    Anesthesiology, 2019, Volume: 130, Issue:2

    Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Disease Models, Animal; Female; Isoflurane; Male

2019
Nitric oxide donor molsidomine promotes retrieval of object recognition memory in a model of cognitive deficit induced by 192 IgG-saporin.
    Behavioural brain research, 2019, 07-02, Volume: 366

    Topics: Acetylcholine; Animals; Antibodies, Monoclonal; Choline O-Acetyltransferase; Cholinergic Neurons; Co

2019
The nitric oxide (NO) donor molsidomine antagonizes scopolamine and L-NAME-induced performance deficits in a spatial memory task in the rat.
    Behavioural brain research, 2009, Jun-08, Volume: 200, Issue:1

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory

2009
The nitric oxide-releasing derivative of ferulic acid NCX 2057 antagonized delay-dependent and scopolamine-induced performance deficits in a recognition memory task in the rat.
    Progress in neuro-psychopharmacology & biological psychiatry, 2010, Feb-01, Volume: 34, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Butanes; Coumaric Acids; Disease Models, Animal; Dr

2010
Molsidomine attenuates N(omega)-nitro-L-argininemethylester-induced deficits in a memory task in the rat.
    European journal of pharmacology, 2002, Sep-27, Volume: 452, Issue:1

    Topics: Amnesia; Animals; Cognition; Discrimination, Psychological; Enzyme Inhibitors; Male; Memory Disorder

2002
The nitric oxide donor molsidomine antagonizes age-related memory deficits in the rat.
    Neurobiology of aging, 2005, Volume: 26, Issue:2

    Topics: Age Factors; Aging; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Dose-Respon

2005