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molsidomine and Absence Seizure

molsidomine has been researched along with Absence Seizure in 1 studies

Molsidomine: A morpholinyl sydnone imine ethyl ester, having a nitrogen in place of the keto oxygen. It acts as NITRIC OXIDE DONORS and is a vasodilator that has been used in ANGINA PECTORIS.
molsidomine : A member of the class of oxadiazoles that is 1,2,3-oxadiazole substituted by morpholin-4-yl and (ethoxycarbonyl)azanidyl groups at positions 3 and 5, respectively. It is used as a vasodilator drug for the treatment of myocardial ischemic syndrome and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"Molsidomine (25 mg kg(-1)), a donor of nitric oxide, commonly used in the treatment of coronary artery disease, enhanced the protective activity of valproate against the clonic phase of pentylenetetrazole-induced seizures in mice, significantly reducing the ED(50) of valproate from 123."7.71Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice. ( Arent, K; Kleinrok, Z; Tutka, P; Wielosz, M; Łuszczki, J, 2002)
"Molsidomine (25 mg kg(-1)), a donor of nitric oxide, commonly used in the treatment of coronary artery disease, enhanced the protective activity of valproate against the clonic phase of pentylenetetrazole-induced seizures in mice, significantly reducing the ED(50) of valproate from 123."3.71Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice. ( Arent, K; Kleinrok, Z; Tutka, P; Wielosz, M; Łuszczki, J, 2002)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tutka, P1
Łuszczki, J1
Kleinrok, Z1
Arent, K1
Wielosz, M1

Other Studies

1 other study available for molsidomine and Absence Seizure

ArticleYear
Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:4

    Topics: Animals; Anticonvulsants; Convulsants; Drug Synergism; Male; Mice; Molsidomine; Pentylenetetrazole;

2002