mogroside-v and Skin-Neoplasms

mogroside-v has been researched along with Skin-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for mogroside-v and Skin-Neoplasms

Article	Year
Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori. Cancer letters, 2003, Jul-30, Volume: 198, Issue:1 To search for cancer chemopreventive agents from natural resources, many phytochemicals and food additives have been screened. Consequently, two natural sweeteners, mogroside V and 11-oxo-mogroside V isolated from the fruits of Momordica grosvenori, exhibited strong inhibitory effect on the primary screening test indicated by the induction of Epstein-Barr virus early antigen (EBV-EA) by a tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA). These sweet glycosides, having cucurbitane triterpenoid aglycon, exhibited the significant inhibitory effects on the two-stage carcinogenesis test of mouse skin tumors induced by peroxynitrite (ONOO-) as an initiator and TPA as a promoter. Further, 11-oxo-mogroside V also exhibited the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin tumor induced by 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter. Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cells, Cultured; Cocarcinogenesis; Female; Lymphocytes; Mice; Mice, Inbred ICR; Momordica; Peroxynitrous Acid; Skin Neoplasms; Sweetening Agents; Tetradecanoylphorbol Acetate; Triterpenes	2003

Article

Year

Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori.

Cancer letters, 2003, Jul-30, Volume: 198, Issue:1

To search for cancer chemopreventive agents from natural resources, many phytochemicals and food additives have been screened. Consequently, two natural sweeteners, mogroside V and 11-oxo-mogroside V isolated from the fruits of Momordica grosvenori, exhibited strong inhibitory effect on the primary screening test indicated by the induction of Epstein-Barr virus early antigen (EBV-EA) by a tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA). These sweet glycosides, having cucurbitane triterpenoid aglycon, exhibited the significant inhibitory effects on the two-stage carcinogenesis test of mouse skin tumors induced by peroxynitrite (ONOO-) as an initiator and TPA as a promoter. Further, 11-oxo-mogroside V also exhibited the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin tumor induced by 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter.

Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cells, Cultured; Cocarcinogenesis; Female; Lymphocytes; Mice; Mice, Inbred ICR; Momordica; Peroxynitrous Acid; Skin Neoplasms; Sweetening Agents; Tetradecanoylphorbol Acetate; Triterpenes

2003