Page last updated: 2024-10-31

modafinil and Stevens-Johnson Syndrome

modafinil has been researched along with Stevens-Johnson Syndrome in 4 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research Excerpts

ExcerptRelevanceReference
"We present the case of a 21-year-old woman in whom Stevens-Johnson syndrome (SJS) developed after initiation of armodafinil."7.88Stevens-Johnson Syndrome After Armodafinil Use. ( Holfinger, S; Roy, A; Schmidt, M, 2018)
"We present the case of a 21-year-old woman in whom Stevens-Johnson syndrome (SJS) developed after initiation of armodafinil."3.88Stevens-Johnson Syndrome After Armodafinil Use. ( Holfinger, S; Roy, A; Schmidt, M, 2018)
"Modafinil is a nonamphetamine nootropic drug with an increasingly therapeutic interest due to its different sites of action and behavioral effects in comparison to cocaine or amphetamine."2.66Pharmacokinetic and pharmacodynamic of the cognitive enhancer modafinil: Relevant clinical and forensic aspects. ( Dinis-Oliveira, RJ; Sousa, A, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Sousa, A1
Dinis-Oliveira, RJ1
Prince, V1
Philippidou, M1
Walsh, S1
Creamer, D1
Holfinger, S1
Roy, A1
Schmidt, M1
Broadbent, K1

Reviews

1 review available for modafinil and Stevens-Johnson Syndrome

ArticleYear
Pharmacokinetic and pharmacodynamic of the cognitive enhancer modafinil: Relevant clinical and forensic aspects.
    Substance abuse, 2020, Volume: 41, Issue:2

    Topics: Anxiety; Diarrhea; Drug Eruptions; Drug Interactions; Erythema Multiforme; Forensic Sciences; Headac

2020

Other Studies

3 other studies available for modafinil and Stevens-Johnson Syndrome

ArticleYear
Stevens-Johnson syndrome induced by modafinil.
    Clinical and experimental dermatology, 2018, Volume: 43, Issue:2

    Topics: Adult; Female; Humans; Modafinil; Skin; Stevens-Johnson Syndrome; Wakefulness-Promoting Agents

2018
Stevens-Johnson Syndrome After Armodafinil Use.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018, 05-15, Volume: 14, Issue:5

    Topics: Female; Humans; Idiopathic Hypersomnia; Modafinil; Skin; Stevens-Johnson Syndrome; Wakefulness-Promo

2018
A surprising presentation of blistering mouth ulcers.
    Australian family physician, 2016, Volume: 45, Issue:3

    Topics: Adult; Benzhydryl Compounds; Blister; Diagnosis, Differential; Humans; Male; Modafinil; Oral Ulcer;

2016