modafinil has been researched along with Smoking Cessation in 5 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Smoking Cessation: Discontinuing the habit of SMOKING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred and fifty-seven treatment-seeking smokers received brief smoking cessation counseling and were randomized to: (1) 8 weeks of modafinil (200mg/day), or (2) 8 weeks of placebo." | 5.13 | A placebo-controlled trial of modafinil for nicotine dependence. ( Berrettini, W; Dackis, C; Gariti, P; Heitjan, DF; Leone, F; Lerman, C; Perkins, KA; Pinto, A; Schnoll, RA; Siegel, S; Wileyto, EP, 2008) |
| "These results indicate that therapeutics which may be useful for smoking cessation via selective inhibition of α4β2* or α6β2* nAChRs, or DAT inhibition, may not be sufficient to treat EtOH and nicotine co-use." | 3.88 | Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats. ( Bardo, MT; Baxter, TA; Bell, RL; Crooks, P; Dwoskin, LP; Maggio, SE; Newman, AH; Nixon, K; Prendergast, MA; Saunders, MA; Slack, RD; Zheng, G, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maggio, SE | 1 |
| Saunders, MA | 1 |
| Baxter, TA | 1 |
| Nixon, K | 1 |
| Prendergast, MA | 1 |
| Zheng, G | 1 |
| Crooks, P | 1 |
| Dwoskin, LP | 1 |
| Slack, RD | 1 |
| Newman, AH | 1 |
| Bell, RL | 1 |
| Bardo, MT | 1 |
| Perkins, KA | 2 |
| Lerman, C | 2 |
| Karelitz, JL | 1 |
| Jao, NC | 1 |
| Chengappa, KN | 1 |
| Sparks, GM | 1 |
| Martin, CA | 1 |
| Lile, J | 1 |
| Guenthner, G | 1 |
| Anestis, JC | 1 |
| Batten, SR | 1 |
| Kelly, TH | 1 |
| Schnoll, RA | 1 |
| Wileyto, EP | 1 |
| Pinto, A | 1 |
| Leone, F | 1 |
| Gariti, P | 1 |
| Siegel, S | 1 |
| Dackis, C | 1 |
| Heitjan, DF | 1 |
| Berrettini, W | 1 |
| Sofuoglu, M | 1 |
| Waters, AJ | 1 |
| Mooney, M | 1 |
3 trials available for modafinil and Smoking Cessation
| Article | Year |
|---|---|
Behavioral effects of modafinil and nicotine, alone and in combination, in tobacco-deprived young adult smokers.
Topics: Adolescent; Benzhydryl Compounds; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therap | 2014 |
A placebo-controlled trial of modafinil for nicotine dependence.
Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Double-Blind Method; Female; Humans; | 2008 |
Modafinil and nicotine interactions in abstinent smokers.
Topics: Adult; Benzhydryl Compounds; Blood Pressure; Central Nervous System Stimulants; Cross-Over Studies; | 2008 |
2 other studies available for modafinil and Smoking Cessation
| Article | Year |
|---|---|
Effects of the nicotinic agonist varenicline, nicotinic antagonist r-bPiDI, and DAT inhibitor (R)-modafinil on co-use of ethanol and nicotine in female P rats.
Topics: Alcohol Drinking; Animals; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, | 2018 |
Sensitivity and specificity of a procedure for early human screening of novel smoking cessation medications.
Topics: Adult; Benzhydryl Compounds; Bupropion; Carbon Monoxide; Cross-Over Studies; Dopamine Uptake Inhibit | 2013 |