Page last updated: 2024-10-31

modafinil and Sarcoidosis

modafinil has been researched along with Sarcoidosis in 2 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.

Research Excerpts

ExcerptRelevanceReference
"This was a double-blind, placebo-controlled, crossover study of sarcoidosis patients followed up in one sarcoidosis clinic Sarcoidosis patients with fatigue received either armodafinil or placebo with eight weeks of therapy for each arm and a two week washout period before crossover to the other treatment."9.17Armodafinil for sarcoidosis-associated fatigue: a double-blind, placebo-controlled, crossover trial. ( Baughman, RP; Lower, EE; Malhotra, A; Surdulescu, V, 2013)
"This was a double-blind, placebo-controlled, crossover study of sarcoidosis patients followed up in one sarcoidosis clinic Sarcoidosis patients with fatigue received either armodafinil or placebo with eight weeks of therapy for each arm and a two week washout period before crossover to the other treatment."5.17Armodafinil for sarcoidosis-associated fatigue: a double-blind, placebo-controlled, crossover trial. ( Baughman, RP; Lower, EE; Malhotra, A; Surdulescu, V, 2013)
"Trial evidence for treating fatigue as a manifestation of sarcoidosis is limited and requires further investigation."2.55Managing fatigue in sarcoidosis - A systematic review of the evidence. ( Atkins, C; Wilson, AM, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atkins, C1
Wilson, AM1
Lower, EE1
Malhotra, A1
Surdulescu, V1
Baughman, RP1

Reviews

1 review available for modafinil and Sarcoidosis

ArticleYear
Managing fatigue in sarcoidosis - A systematic review of the evidence.
    Chronic respiratory disease, 2017, Volume: 14, Issue:2

    Topics: Adalimumab; Antirheumatic Agents; Benzhydryl Compounds; Central Nervous System Stimulants; Exercise

2017

Trials

1 trial available for modafinil and Sarcoidosis

ArticleYear
Armodafinil for sarcoidosis-associated fatigue: a double-blind, placebo-controlled, crossover trial.
    Journal of pain and symptom management, 2013, Volume: 45, Issue:2

    Topics: Adult; Benzhydryl Compounds; Central Nervous System Stimulants; Cross-Over Studies; Dose-Response Re

2013