modafinil has been researched along with Postpoliomyelitis Syndrome in 3 studies
Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.
Postpoliomyelitis Syndrome: A syndrome characterized by new neuromuscular symptoms that occur at least 15 years after clinical stability has been attained in patients with a prior history of symptomatic poliomyelitis. Clinical features include new muscular weakness and atrophy of the limbs, bulbar innervated musculature, and muscles of respiration, combined with excessive fatigue, joint pain, and reduced stamina. The process is marked by slow progression and periods of stabilization. (From Ann NY Acad Sci 1995 May 25;753:68-80)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to test whether modafinil is effective in alleviating the symptoms of fatigue in postpolio patients, because it has been helpful for such symptoms in other neurologic disorders." | 9.12 | Randomized controlled trial of modafinil for the treatment of fatigue in postpolio patients. ( Allidina, A; Chan, KM; Rydz, D; Shuaib, A; Strohschein, FJ; Westbury, CF, 2006) |
| "To determine if modafinil can improve fatigue in patients with post-polio syndrome." | 9.12 | Modafinil for treatment of fatigue in post-polio syndrome: a randomized controlled trial. ( Campbell, WW; Dalakas, MC; Halstead, LS; Jabbari, B; Kelley, KF; Livornese, K; Olsen, CH; Prokhorenko, OA; Salajegheh, MK; Vasconcelos, OM; Vo, AH, 2007) |
| "The purpose of this study was to test whether modafinil is effective in alleviating the symptoms of fatigue in postpolio patients, because it has been helpful for such symptoms in other neurologic disorders." | 5.12 | Randomized controlled trial of modafinil for the treatment of fatigue in postpolio patients. ( Allidina, A; Chan, KM; Rydz, D; Shuaib, A; Strohschein, FJ; Westbury, CF, 2006) |
| "To determine if modafinil can improve fatigue in patients with post-polio syndrome." | 5.12 | Modafinil for treatment of fatigue in post-polio syndrome: a randomized controlled trial. ( Campbell, WW; Dalakas, MC; Halstead, LS; Jabbari, B; Kelley, KF; Livornese, K; Olsen, CH; Prokhorenko, OA; Salajegheh, MK; Vasconcelos, OM; Vo, AH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, KM | 1 |
| Strohschein, FJ | 1 |
| Rydz, D | 1 |
| Allidina, A | 1 |
| Shuaib, A | 1 |
| Westbury, CF | 1 |
| Vasconcelos, OM | 1 |
| Prokhorenko, OA | 1 |
| Salajegheh, MK | 1 |
| Kelley, KF | 1 |
| Livornese, K | 1 |
| Olsen, CH | 1 |
| Vo, AH | 1 |
| Dalakas, MC | 1 |
| Halstead, LS | 1 |
| Jabbari, B | 1 |
| Campbell, WW | 1 |
| Rison, RA | 1 |
2 trials available for modafinil and Postpoliomyelitis Syndrome
| Article | Year |
|---|---|
Randomized controlled trial of modafinil for the treatment of fatigue in postpolio patients.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Double-Blind Method; Fatigue; Female; Human | 2006 |
Modafinil for treatment of fatigue in post-polio syndrome: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Benzhydryl Compounds; Central Nervous System Stimulants; Cross-Over Studies | 2007 |
1 other study available for modafinil and Postpoliomyelitis Syndrome
| Article | Year |
|---|---|
Re: Modafinil for treatment of fatigue in post-polio syndrome: a randomized controlled trial.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Comorbidity; Diagnosis, Differential; Fatig | 2008 |