Page last updated: 2024-10-31

modafinil and Obesity

modafinil has been researched along with Obesity in 5 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that wakefulness-promoter armodafinil would improve driving task performance over placebo in patients undergoing weight loss."9.27Does Armodafinil Improve Driving Task Performance and Weight Loss in Sleep Apnea? A Randomized Trial. ( Cayanan, EA; Chapman, JL; Comas, M; Grunstein, RR; Hoyos, CM; Marshall, NS; Serinel, Y; Wong, KKH; Yee, BJ, 2018)
"We hypothesized that wakefulness-promoter armodafinil would improve driving task performance over placebo in patients undergoing weight loss."5.27Does Armodafinil Improve Driving Task Performance and Weight Loss in Sleep Apnea? A Randomized Trial. ( Cayanan, EA; Chapman, JL; Comas, M; Grunstein, RR; Hoyos, CM; Marshall, NS; Serinel, Y; Wong, KKH; Yee, BJ, 2018)
" Modafinil may be well suited for the treatment of obesity, although further studies with repeated dosing in overweight populations are warranted."2.71Wake-promoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity. ( Frederich, RC; Kelly, TH; Makris, AP; Rush, CR, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, JL1
Cayanan, EA1
Hoyos, CM1
Serinel, Y1
Comas, M1
Yee, BJ1
Wong, KKH1
Grunstein, RR1
Marshall, NS1
Andrade, C1
Makris, AP1
Rush, CR1
Frederich, RC1
Kelly, TH1
Plazzi, G1
Parmeggiani, A1
Mignot, E1
Lin, L1
Scano, MC1
Posar, A1
Bernardi, F1
Lodi, R1
Tonon, C1
Barbiroli, B1
Montagna, P1
Cicognani, A1
Carl, D1
Sica, DA1

Reviews

1 review available for modafinil and Obesity

ArticleYear
Obstructive sleep apnea, hypertension, and wakefulness-promoting agents.
    Current hypertension reports, 2007, Volume: 9, Issue:4

    Topics: Benzhydryl Compounds; Blood Pressure; Central Nervous System Stimulants; Circadian Rhythm; Heart Rat

2007

Trials

2 trials available for modafinil and Obesity

ArticleYear
Does Armodafinil Improve Driving Task Performance and Weight Loss in Sleep Apnea? A Randomized Trial.
    American journal of respiratory and critical care medicine, 2018, 10-01, Volume: 198, Issue:7

    Topics: Adult; Australia; Automobile Driving; Combined Modality Therapy; Diet, Reducing; Double-Blind Method

2018
Wake-promoting agents with different mechanisms of action: comparison of effects of modafinil and amphetamine on food intake and cardiovascular activity.
    Appetite, 2004, Volume: 42, Issue:2

    Topics: Adult; Amphetamine; Benzhydryl Compounds; Blood Pressure; Cardiovascular Physiological Phenomena; Ce

2004

Other Studies

2 other studies available for modafinil and Obesity

ArticleYear
Modafinil and armodafinil in schizophrenia.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:8

    Topics: Antipsychotic Agents; Benzhydryl Compounds; Central Nervous System Stimulants; Cytochrome P-450 CYP1

2012
Narcolepsy-cataplexy associated with precocious puberty.
    Neurology, 2006, May-23, Volume: 66, Issue:10

    Topics: Aspartic Acid; Benzhydryl Compounds; Cataplexy; Child; Creatine; Cyclohexanols; Disorders of Excessi

2006