Page last updated: 2024-10-31

modafinil and Neuralgia

modafinil has been researched along with Neuralgia in 3 studies

Modafinil: A benzhydryl acetamide compound, central nervous system stimulant, and CYP3A4 inducing agent that is used in the treatment of NARCOLEPSY and SLEEP WAKE DISORDERS.
modafinil : A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
2-[(diphenylmethyl)sulfinyl]acetamide : A sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group.

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
" On the contrary, suppression of EEG delta power using a wake-promoting agent modafinil significantly attenuated mechanical allodynia."3.96High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice. ( Ge, J; Hong, ZY; Huang, ZL; Lazarus, M; Li, YD; Luo, YJ; Qu, WM; Wang, J; Xu, W, 2020)
"We assessed prescription patterns for four top-selling orphan drugs: lidocaine patch (Lidoderm) approved for post-herpetic neuralgia, modafinil (Provigil) approved for narcolepsy, cinacalcet (Sensipar) approved for hypercalcemia of parathyroid carcinoma, and imatinib (Gleevec) approved for chronic myelogenous leukemia and gastrointestinal stromal tumor."3.78The prevalence and cost of unapproved uses of top-selling orphan drugs. ( Avorn, J; Kesselheim, AS; Levin, R; Myers, JA; Solomon, DH; Winkelmayer, WC, 2012)
"Pre-treatment with modafinil prevented sensorimotor neuropathy by raising latencies, MNCV and excitation, reducing TRPA1, TNF-α and IL-1β levels."1.56The protective effect of modafinil on vincristine-induced peripheral neuropathy in rats: A possible role for TRPA1 receptors. ( Abdollahi, A; Amirkhanloo, F; Dehpour, AR; Karimi, G; Roohbakhsh, A; Yousefi-Manesh, H, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Li, YD1
Ge, J1
Luo, YJ1
Xu, W1
Wang, J1
Lazarus, M1
Hong, ZY1
Qu, WM1
Huang, ZL1
Amirkhanloo, F1
Karimi, G1
Yousefi-Manesh, H1
Abdollahi, A1
Roohbakhsh, A1
Dehpour, AR1
Kesselheim, AS1
Myers, JA1
Solomon, DH1
Winkelmayer, WC1
Levin, R1
Avorn, J1

Other Studies

3 other studies available for modafinil and Neuralgia

ArticleYear
High cortical delta power correlates with aggravated allodynia by activating anterior cingulate cortex GABAergic neurons in neuropathic pain mice.
    Pain, 2020, Volume: 161, Issue:2

    Topics: Adrenergic Uptake Inhibitors; Animals; Cerebral Cortex; Cholinergic Antagonists; Cortical Synchroniz

2020
The protective effect of modafinil on vincristine-induced peripheral neuropathy in rats: A possible role for TRPA1 receptors.
    Basic & clinical pharmacology & toxicology, 2020, Volume: 127, Issue:5

    Topics: Animals; Cytokines; Gabapentin; Hyperalgesia; Interleukin-1beta; Modafinil; Neural Conduction; Neura

2020
The prevalence and cost of unapproved uses of top-selling orphan drugs.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Benzhydryl Compounds; Cinacalcet; Costs and Cost Analysis; Drug Approval; Humans; Lidocaine; Modafin

2012